KR20200018438A - 향상된 용해도의 약물-함유 제형 - Google Patents

향상된 용해도의 약물-함유 제형 Download PDF

Info

Publication number
KR20200018438A
KR20200018438A KR1020197036432A KR20197036432A KR20200018438A KR 20200018438 A KR20200018438 A KR 20200018438A KR 1020197036432 A KR1020197036432 A KR 1020197036432A KR 20197036432 A KR20197036432 A KR 20197036432A KR 20200018438 A KR20200018438 A KR 20200018438A
Authority
KR
South Korea
Prior art keywords
acid
drug
acids
composition
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020197036432A
Other languages
English (en)
Korean (ko)
Inventor
마이클 레어드 허리
드라젠 오스토빅
피터 노이머
Original Assignee
스테디메드 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스테디메드 리미티드 filed Critical 스테디메드 리미티드
Publication of KR20200018438A publication Critical patent/KR20200018438A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020197036432A 2017-05-11 2018-05-10 향상된 용해도의 약물-함유 제형 Ceased KR20200018438A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762504546P 2017-05-11 2017-05-11
US62/504,546 2017-05-11
PCT/IL2018/050511 WO2018207188A1 (en) 2017-05-11 2018-05-10 Enhanced solubility drug-containing formulations

Publications (1)

Publication Number Publication Date
KR20200018438A true KR20200018438A (ko) 2020-02-19

Family

ID=62599659

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197036432A Ceased KR20200018438A (ko) 2017-05-11 2018-05-10 향상된 용해도의 약물-함유 제형

Country Status (9)

Country Link
US (1) US11672863B2 (enExample)
EP (1) EP3621591A1 (enExample)
JP (1) JP2020519593A (enExample)
KR (1) KR20200018438A (enExample)
CN (1) CN110869000A (enExample)
AU (1) AU2018265624A1 (enExample)
CA (1) CA3063322A1 (enExample)
IL (1) IL271673A (enExample)
WO (1) WO2018207188A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200018438A (ko) 2017-05-11 2020-02-19 스테디메드 리미티드 향상된 용해도의 약물-함유 제형
JP7190077B2 (ja) * 2019-08-01 2022-12-14 インカーダ セラピューティクス, インコーポレイテッド 抗不整脈製剤

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910260A (en) 1972-03-01 1975-10-07 Survival Technology Method and apparatus of treating heart attack patients prior to the establishment of qualified direct contact personal care
US4004577A (en) 1972-12-04 1977-01-25 Survival Technology, Inc. Method of treating heart attack patients prior to the establishment of qualified direct contact personal care
US3941130A (en) 1975-03-18 1976-03-02 Tibbs Robert C Sequential trigger release for injection device
US4261358A (en) 1979-10-01 1981-04-14 Walter Vargas Automatic syringe plunger
US4795433A (en) 1985-05-20 1989-01-03 Survival Technology, Inc. Automatic injector for emergency treatment
US4689042A (en) 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4902692A (en) * 1988-03-18 1990-02-20 Iolab Corporation Method and composition for ophthalmic anesthesia using rodocaine
US5085642A (en) 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use autoinjector
US5102393A (en) 1989-07-17 1992-04-07 Survival Technology, Inc. Autoinjector converted from intramuscular to subcutaneous mode of injection
US5092843A (en) 1990-04-12 1992-03-03 Survival Technology, Inc. Dispersion multichamber auto-injector
US5267963A (en) 1992-08-21 1993-12-07 Nicholas Bachynsky Medication injection device
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5618563A (en) * 1992-09-10 1997-04-08 Children's Medical Center Corporation Biodegradable polymer matrices for sustained delivery of local anesthetic agents
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
US5747060A (en) * 1996-03-26 1998-05-05 Euro-Celtique, S.A. Prolonged local anesthesia with colchicine
EP1014946B1 (en) * 1997-09-18 2010-04-07 Pacira Pharmaceuticals, Inc. Sustained-release liposomal anesthetic compositions
US6149626A (en) 1997-10-03 2000-11-21 Bachynsky; Nicholas Automatic injecting syringe apparatus
SE9803662D0 (sv) 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab Autoinjector
JP4775807B2 (ja) * 2004-12-02 2011-09-21 株式会社 メドレックス 局所麻酔薬物含有ゼリー剤
US20060270708A1 (en) * 2005-05-25 2006-11-30 Navinta Llc Novel process for preparation of isotonic aqueous injection of ropivacaine
JP5535623B2 (ja) 2006-06-30 2014-07-02 アッヴィ バイオテクノロジー リミテッド 自動注射装置
CN101744760A (zh) * 2008-12-18 2010-06-23 梁颖 用于难溶性或易分解性药物的缓释体
CN102106806B (zh) * 2009-12-29 2013-04-17 上海中西制药有限公司 一种固体制剂的制备方法及所得固体制剂
EP3169316A4 (en) * 2014-07-15 2018-01-24 Isa Odidi Compositions and methods for reducing overdose
AU2016352007B2 (en) * 2015-11-12 2022-03-17 Terumo Kabushiki Kaisha Sustained-release topically administered agent
KR20200018438A (ko) 2017-05-11 2020-02-19 스테디메드 리미티드 향상된 용해도의 약물-함유 제형

Also Published As

Publication number Publication date
CA3063322A1 (en) 2018-11-15
IL271673A (en) 2020-02-27
JP2020519593A (ja) 2020-07-02
US11672863B2 (en) 2023-06-13
EP3621591A1 (en) 2020-03-18
US20200054754A1 (en) 2020-02-20
CN110869000A (zh) 2020-03-06
AU2018265624A1 (en) 2019-12-05
WO2018207188A1 (en) 2018-11-15

Similar Documents

Publication Publication Date Title
US11304913B2 (en) Analgesic compositions
JP5185488B2 (ja) 2−(4−イソブチルフェニル)プロピオン酸の医薬組成物
CN115804771A (zh) 一种具有长效缓释作用的脂质释药系统及其制备方法
US11672863B2 (en) Enhanced solubility drug-containing formulations
AU2011273064A1 (en) Pharmaceutical compositions comprising paracetamol and process for preparing the same
WO2017132243A1 (en) Aqueous pharmaceutical formulation comprising propofol
WO2007022609A1 (en) Pharmaceutical composition of morphine in ready-to-use injectable solution form and single dosage form of morphine for epidural or intrathecal administration
WO2011047639A1 (zh) 一种含有螯合剂的紫杉烷类药物溶液及其制备方法
US20220378719A1 (en) Analgesic compositions comprising halogenated volatile compounds
KR102118227B1 (ko) 척추 투여용 과포화 아세타미노펜 주사 용액
CA2994748A1 (en) Pharmaceutical composition comprising sumatripan for treating migraine
TWI472340B (zh) Taxanes containing solution and a preparation method of the co-solvent
WO2011047636A1 (zh) 一种含有助溶剂的紫杉烷类药物溶液及其制备方法

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20191210

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20210507

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20230520

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20230828

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20230520

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I