KR20200017386A - 각막 이상증과 관련된 대립유전자의 다중 검출을 위한 방법 - Google Patents

각막 이상증과 관련된 대립유전자의 다중 검출을 위한 방법 Download PDF

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KR20200017386A
KR20200017386A KR1020197032795A KR20197032795A KR20200017386A KR 20200017386 A KR20200017386 A KR 20200017386A KR 1020197032795 A KR1020197032795 A KR 1020197032795A KR 20197032795 A KR20197032795 A KR 20197032795A KR 20200017386 A KR20200017386 A KR 20200017386A
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tgfbi
probe
labeled
seq
reaction mixture
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KR1020197032795A
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KR102701188B1 (ko
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코니 차오-션
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아벨리노 랩 유에스에이, 인크.
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
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    • G01MEASURING; TESTING
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
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  • Health & Medical Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Urology & Nephrology (AREA)
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  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020197032795A 2017-04-10 2018-04-10 각막 이상증과 관련된 대립유전자의 다중 검출을 위한 방법 KR102701188B1 (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201762483588P 2017-04-10 2017-04-10
US62/483,588 2017-04-10
US201762573537P 2017-10-17 2017-10-17
US62/573,537 2017-10-17
US201862624660P 2018-01-31 2018-01-31
US201862624661P 2018-01-31 2018-01-31
US62/624,661 2018-01-31
US62/624,660 2018-01-31
PCT/US2018/026962 WO2018191304A1 (en) 2017-04-10 2018-04-10 Methods for multiplex detection of alleles associated with corneal dystrophy

Publications (2)

Publication Number Publication Date
KR20200017386A true KR20200017386A (ko) 2020-02-18
KR102701188B1 KR102701188B1 (ko) 2024-08-30

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KR1020197032795A KR102701188B1 (ko) 2017-04-10 2018-04-10 각막 이상증과 관련된 대립유전자의 다중 검출을 위한 방법

Country Status (8)

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US (1) US11905560B2 (de)
EP (1) EP3610015A4 (de)
JP (2) JP7303113B2 (de)
KR (1) KR102701188B1 (de)
CN (1) CN110945126B (de)
AU (1) AU2018250570A1 (de)
CA (1) CA3059591A1 (de)
WO (1) WO2018191304A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102241836B1 (ko) * 2019-06-14 2021-04-21 솔젠트 (주) 듀얼 체크 올리고를 이용한 유전자 다형성 검사 방법
CN113848327A (zh) * 2021-09-18 2021-12-28 天津市眼科医院 用于高度近视风险预测以及高度近视辅助诊断的标志物组合物及其应用
CN116024335A (zh) * 2023-02-14 2023-04-28 福建佰孟医学科技有限公司 一种角膜营养不良基因突变检测引物组合物、试剂盒及检测方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070076532A (ko) * 2006-01-18 2007-07-24 메디제네스(주) 각막이영양증 진단용 dna 칩
KR20110018702A (ko) * 2009-08-18 2011-02-24 한국과학기술원 다중 스팟 금속 증착형 나노구조배열 각막이상증 진단용 핵산칩 및 이의 제조방법
KR20160088028A (ko) * 2015-01-15 2016-07-25 정정원 Tgfbi-연관 각막이상증 진단방법 및 키트

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962332A (en) * 1994-03-17 1999-10-05 University Of Massachusetts Detection of trinucleotide repeats by in situ hybridization
US20120208196A1 (en) 2009-10-30 2012-08-16 Mitsuharu Hirai Probe for Detecting Polymorphism in MPL Gene and Use of the Probe
KR101320943B1 (ko) 2010-04-20 2013-10-23 연세대학교 산학협력단 Tgfbi 유전자 변이 각막 이상증의 예방 또는 치료용 약제학적 조성물 및 그의 스크리닝 방법
KR101258166B1 (ko) 2010-09-01 2013-04-25 연세대학교 산학협력단 Tgfbi 유전자 변이 각막 이상증의 예방 또는 치료용 약제학적 조성물 및 그의 스크리닝 방법
KR101125212B1 (ko) 2010-10-01 2012-03-21 (주)아벨리노 아벨리노 각막이상증 진단용 시스템
TWI812047B (zh) 2013-11-15 2023-08-11 美商阿韋利諾美國實驗有限公司 用於多工偵測與眼科病況有關的對偶基因之方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070076532A (ko) * 2006-01-18 2007-07-24 메디제네스(주) 각막이영양증 진단용 dna 칩
KR20110018702A (ko) * 2009-08-18 2011-02-24 한국과학기술원 다중 스팟 금속 증착형 나노구조배열 각막이상증 진단용 핵산칩 및 이의 제조방법
KR20160088028A (ko) * 2015-01-15 2016-07-25 정정원 Tgfbi-연관 각막이상증 진단방법 및 키트

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Invest Ophthalmol Vis Sci,57(13):5407-5414. (2016.10.01.) *

Also Published As

Publication number Publication date
JP7303113B2 (ja) 2023-07-04
CN110945126A (zh) 2020-03-31
US20200040397A1 (en) 2020-02-06
CN110945126B (zh) 2024-04-26
KR102701188B1 (ko) 2024-08-30
CA3059591A1 (en) 2018-10-18
EP3610015A1 (de) 2020-02-19
WO2018191304A1 (en) 2018-10-18
AU2018250570A1 (en) 2019-11-21
JP2023116533A (ja) 2023-08-22
JP2020516280A (ja) 2020-06-11
EP3610015A4 (de) 2021-05-19
US11905560B2 (en) 2024-02-20

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