KR20200012823A - 이뇨제 내성의 치료 - Google Patents

이뇨제 내성의 치료 Download PDF

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Publication number
KR20200012823A
KR20200012823A KR1020197025663A KR20197025663A KR20200012823A KR 20200012823 A KR20200012823 A KR 20200012823A KR 1020197025663 A KR1020197025663 A KR 1020197025663A KR 20197025663 A KR20197025663 A KR 20197025663A KR 20200012823 A KR20200012823 A KR 20200012823A
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KR
South Korea
Prior art keywords
antibody
leu
ser
val
patient
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Ceased
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KR1020197025663A
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English (en)
Korean (ko)
Inventor
제프리 테스타니
비나 라오
라훌 카카르
매드하브 엔 데발라라자
치헝 로
Original Assignee
예일 유니버시티
코비디아 테라퓨틱스, 인크.
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Application filed by 예일 유니버시티, 코비디아 테라퓨틱스, 인크. filed Critical 예일 유니버시티
Priority to KR1020257005525A priority Critical patent/KR20250029283A/ko
Publication of KR20200012823A publication Critical patent/KR20200012823A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020197025663A 2017-02-01 2018-02-01 이뇨제 내성의 치료 Ceased KR20200012823A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257005525A KR20250029283A (ko) 2017-02-01 2018-02-01 이뇨제 내성의 치료

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762453257P 2017-02-01 2017-02-01
US62/453,257 2017-02-01
PCT/US2018/016508 WO2018144773A1 (en) 2017-02-01 2018-02-01 Treatment of diuretic resistance

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020257005525A Division KR20250029283A (ko) 2017-02-01 2018-02-01 이뇨제 내성의 치료

Publications (1)

Publication Number Publication Date
KR20200012823A true KR20200012823A (ko) 2020-02-05

Family

ID=63040146

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020197025663A Ceased KR20200012823A (ko) 2017-02-01 2018-02-01 이뇨제 내성의 치료
KR1020257005525A Pending KR20250029283A (ko) 2017-02-01 2018-02-01 이뇨제 내성의 치료

Family Applications After (1)

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KR1020257005525A Pending KR20250029283A (ko) 2017-02-01 2018-02-01 이뇨제 내성의 치료

Country Status (12)

Country Link
US (2) US11203636B2 (https=)
EP (1) EP3576790A4 (https=)
JP (3) JP7630906B2 (https=)
KR (2) KR20200012823A (https=)
CN (1) CN110913900A (https=)
AU (2) AU2018214554C1 (https=)
CA (1) CA3051865C (https=)
IL (2) IL268294B2 (https=)
MX (1) MX390722B (https=)
SG (2) SG10201912128SA (https=)
TW (2) TWI850514B (https=)
WO (1) WO2018144773A1 (https=)

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Publication number Publication date
CN110913900A (zh) 2020-03-24
AU2018214554A1 (en) 2019-09-19
IL268294A (en) 2019-09-26
TW201832780A (zh) 2018-09-16
TW202130366A (zh) 2021-08-16
US12600773B2 (en) 2026-04-14
SG11201906852XA (en) 2019-08-27
IL268294B2 (en) 2023-07-01
KR20250029283A (ko) 2025-03-04
AU2018214554B2 (en) 2022-06-02
JP2024164113A (ja) 2024-11-26
IL281274A (en) 2021-04-29
TWI850514B (zh) 2024-08-01
TW202444416A (zh) 2024-11-16
US11203636B2 (en) 2021-12-21
US20220195033A1 (en) 2022-06-23
MX390722B (es) 2025-03-21
IL268294B1 (en) 2023-03-01
WO2018144773A1 (en) 2018-08-09
JP2020506190A (ja) 2020-02-27
EP3576790A1 (en) 2019-12-11
AU2018214554C1 (en) 2022-12-15
JP7630906B2 (ja) 2025-02-18
CA3051865C (en) 2023-01-17
EP3576790A4 (en) 2020-12-23
TWI716668B (zh) 2021-01-21
SG10201912128SA (en) 2020-02-27
AU2022221557A1 (en) 2022-11-24
CA3051865A1 (en) 2018-08-09
JP2023002563A (ja) 2023-01-10
US20200079846A1 (en) 2020-03-12

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