JP7630906B2 - 利尿薬耐性の治療 - Google Patents

利尿薬耐性の治療 Download PDF

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Publication number
JP7630906B2
JP7630906B2 JP2019541430A JP2019541430A JP7630906B2 JP 7630906 B2 JP7630906 B2 JP 7630906B2 JP 2019541430 A JP2019541430 A JP 2019541430A JP 2019541430 A JP2019541430 A JP 2019541430A JP 7630906 B2 JP7630906 B2 JP 7630906B2
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antibody
certain embodiments
patient
diuretic
antagonist
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Japanese (ja)
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JP2020506190A5 (https=
JP2020506190A (ja
Inventor
テスタニ，ジェフリー
ラオ，ヴェーナ
カッカー，レイフル
エヌ． デヴァララジャ，マドハブ
ロ，チー－フン
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Novo Nordisk AS
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Novo Nordisk AS
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Priority to JP2022155644A priority Critical patent/JP2023002563A/ja
Priority to JP2024139009A priority patent/JP2024164113A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019541430A 2017-02-01 2018-02-01 利尿薬耐性の治療 Active JP7630906B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022155644A JP2023002563A (ja) 2017-02-01 2022-09-29 利尿薬耐性の治療
JP2024139009A JP2024164113A (ja) 2017-02-01 2024-08-20 利尿薬耐性の治療

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762453257P 2017-02-01 2017-02-01
US62/453,257 2017-02-01
PCT/US2018/016508 WO2018144773A1 (en) 2017-02-01 2018-02-01 Treatment of diuretic resistance

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2022155644A Division JP2023002563A (ja) 2017-02-01 2022-09-29 利尿薬耐性の治療
JP2024139009A Division JP2024164113A (ja) 2017-02-01 2024-08-20 利尿薬耐性の治療

Publications (3)

Publication Number Publication Date
JP2020506190A JP2020506190A (ja) 2020-02-27
JP2020506190A5 JP2020506190A5 (https=) 2021-12-16
JP7630906B2 true JP7630906B2 (ja) 2025-02-18

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019541430A Active JP7630906B2 (ja) 2017-02-01 2018-02-01 利尿薬耐性の治療
JP2022155644A Withdrawn JP2023002563A (ja) 2017-02-01 2022-09-29 利尿薬耐性の治療
JP2024139009A Pending JP2024164113A (ja) 2017-02-01 2024-08-20 利尿薬耐性の治療

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JP2022155644A Withdrawn JP2023002563A (ja) 2017-02-01 2022-09-29 利尿薬耐性の治療
JP2024139009A Pending JP2024164113A (ja) 2017-02-01 2024-08-20 利尿薬耐性の治療

Country Status (12)

Country Link
US (2) US11203636B2 (https=)
EP (1) EP3576790A4 (https=)
JP (3) JP7630906B2 (https=)
KR (2) KR20200012823A (https=)
CN (1) CN110913900A (https=)
AU (2) AU2018214554C1 (https=)
CA (1) CA3051865C (https=)
IL (2) IL268294B2 (https=)
MX (1) MX390722B (https=)
SG (2) SG10201912128SA (https=)
TW (2) TWI850514B (https=)
WO (1) WO2018144773A1 (https=)

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KR20200012823A (ko) 2017-02-01 2020-02-05 예일 유니버시티 이뇨제 내성의 치료
EP3735421A4 (en) 2018-01-05 2021-09-22 Corvidia Therapeutics, Inc. METHOD OF TREATMENT OF IL-6 MEDIATED INFLAMMATION WITHOUT IMMUNSUPPRESSION
JP7701273B2 (ja) 2019-05-01 2025-07-01 ノヴォ ノルディスク アー／エス 抗ｉｌ－６抗体製剤
CN114375205A (zh) * 2019-06-20 2022-04-19 武田药品工业株式会社 用基于病毒的基因疗法进行治疗的方法
US12441707B2 (en) 2019-12-30 2025-10-14 Tyra Biosciences, Inc. Indazole compounds
AR122933A1 (es) 2020-07-10 2022-10-19 Novo Nordisk As Métodos para tratar la enfermedad cardiovascular
TWI907583B (zh) * 2020-12-11 2025-12-11 大陸商江蘇恒瑞醫藥股份有限公司 Jak抑制劑在腎臟疾病中的應用

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