KR20190124852A - Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component - Google Patents

Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component Download PDF

Info

Publication number
KR20190124852A
KR20190124852A KR1020180048820A KR20180048820A KR20190124852A KR 20190124852 A KR20190124852 A KR 20190124852A KR 1020180048820 A KR1020180048820 A KR 1020180048820A KR 20180048820 A KR20180048820 A KR 20180048820A KR 20190124852 A KR20190124852 A KR 20190124852A
Authority
KR
South Korea
Prior art keywords
seed oil
composition
skin
citron seed
collagen
Prior art date
Application number
KR1020180048820A
Other languages
Korean (ko)
Inventor
박이경
김광상
최다인
김민숙
김민지
김화진
유병조
Original Assignee
주식회사 하이솔
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 하이솔 filed Critical 주식회사 하이솔
Priority to KR1020180048820A priority Critical patent/KR20190124852A/en
Publication of KR20190124852A publication Critical patent/KR20190124852A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/318—Foods, ingredients or supplements having a functional effect on health having an effect on skin health and hair or coat

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Botany (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a composition for skin anti-wrinkle effect containing citron seed oil and peptides for collagen activation as an active ingredient. More particularly, since a mixture of citron seed oil and GHK peptides or a mixture of citron seed oil and Cu-GHK peptides is effective for reducing skin wrinkles, the composition of the present invention containing the citron seed oil and peptides for collagen activation as an active ingredient can be usefully used as a material of functional cosmetics or functional health food for skin anti-wrinkle.

Description

유자씨 오일 및 콜라겐 활성 펩티드를 유효성분으로 함유하는 피부 주름개선용 조성물{Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component}Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component

본 발명은 유자씨 오일 및 콜라겐 활성 펩티드 혼합물을 유효성분으로 함유하는 피부 주름개선용 조성물에 관한 것이다.The present invention relates to a composition for improving skin wrinkles containing a mixture of citron seed oil and collagen active peptide as an active ingredient.

피부 노화는 나이가 들어가면서 피부에 나타나게 되는 유형과 무형상의 변화를 통틀어 일컫는다. 피부노화는 연령이 증가함에 따라 생체의 생리적인 기능이 저하되어 자연적으로 유발되는 내인성 생리적 노화와 장기간 자외선 노출에 의해 진행되는 외인성 광노화(photoaging)로 구분될 수 있다. 내인성 피부 노화의 임상적 특징은 피부가 얇아지고, 탄력성이 감소하는 것이다. 또한, 조직학적 소견으로는, 표피 및 진피의 두께가 얇아지고, 혈관이 감소되며, 진피 내의 섬유아세포의 수가 감소하게 되는 것이다. 또한, 외인성 피부 노화인 광노화의 임상적 특징은, 피부가 거칠고 탄력성이 없어지며, 불규칙한 색소 침착이 발생되고, 깊은 주름살이 증가되는 것이다. Skin aging refers to the type and intangible changes that appear on the skin as it ages. Skin aging can be classified into endogenous physiological aging caused by deterioration of physiological function of the living body with age and exogenous photoaging due to prolonged ultraviolet exposure. The clinical feature of endogenous skin aging is thinning of the skin and decreased elasticity. In addition, histological findings include thinning of the epidermis and dermis, decreased blood vessels, and decreased number of fibroblasts in the dermis. In addition, the clinical characteristics of photoaging, which is exogenous skin aging, is that the skin becomes rough and elastic, irregular pigmentation occurs, and deep wrinkles increase.

주름의 생성 원인으로는 여러 가지가 보고되고 있는데, 우선 피부가 과다한 자외선에 노출되면 피부 구성성분인 콜라겐(collagen) 분해가 촉진되어 피부가 탄력을 잃고 주름이 생성될 수 있다. 또한, 피부가 과도한 온도변화 및 습도저하나 바람 등에 의해 지나치게 건조해지면 외부에 대한 방어벽으로서의 피부 기능이 저하되어 주름이 생기기도 한다. 그리고 피부가 활성 산소종이나 자유 라디칼에 노출되면 산화 작용에 의해 과산화 지질이 생성되고 그로 인해 콜라겐 등의 피부 구성 단백질이 변형되어 주름이 생성될 수 있다. 이러한 외부적 요인과 내부적 요인에 의한 주름 발생을 억제하고자 다양한 화장품 조성물이 연구되고 있다. 특히 화학성분이 함유된 기능성 화장품의 경우, 피부 자극을 유발하여 민감성 피부에 적합하지 않은 문제점이 있는 바, 피부에 자극이 적고 친환경적인 천연 식물 유래의 기능성 화장품에 대한 관심이 집중되고 있다.Various causes of wrinkles have been reported. First, when the skin is exposed to excessive ultraviolet rays, the decomposition of collagen (collagen), which is a skin component, is accelerated, and the skin may lose elasticity and wrinkles may be generated. In addition, when the skin becomes excessively dry due to excessive temperature change, low humidity or wind, the skin function as a protective barrier against the outside is degraded and wrinkles may occur. When the skin is exposed to reactive oxygen species or free radicals, lipid peroxide is produced by oxidative action, and as a result, skin component proteins such as collagen may be modified to generate wrinkles. Various cosmetic compositions have been studied to suppress the occurrence of wrinkles caused by such external and internal factors. Particularly, in the case of functional cosmetics containing chemical components, there is a problem that is not suitable for sensitive skin by causing skin irritation, attention is focused on functional cosmetics derived from environmentally friendly natural plants with less irritation to the skin.

한편, 유자는 유자나무의 열매로 껍질이 울퉁불퉁하고 신맛이 특징이다. 주요성분으로 비타민 C가 레몬보다 3배나 많이 들어있어 감기와 피부미용에 좋고, 노화와 피로를 방지하는 유기산이 많이 들어있다. 그밖에 비타민 B와 당질·단백질 등이 다른 감귤류 과일보다 많고 모세혈관을 보호하는 헤스페리딘이 들어있어 뇌혈관 장애와 풍을 막아준다. 또 배농 및 배설작용을 해서 몸 안에 쌓여 있는 노폐물을 밖으로 내보낸다. Yuzu, on the other hand, is a fruit of a citron and has a bumpy bark and a sour taste. Vitamin C contains three times more vitamin C than lemon, which is good for colds and skin care, and contains many organic acids that prevent aging and fatigue. In addition, vitamin B, sugars, and proteins are more than other citrus fruits, and hesperidin protects capillaries and prevents cerebrovascular disorders and wind. In addition, drainage and excretion is to send out the waste accumulated in the body.

또한, 유자씨는 유자 중량의 10 내지 20 중량%를 차지하며, 바이오플라보노이드, 리모노이드 등의 유효성분이 풍부하고, 항산화성을 가진 물질도 함유하고 있어 다양한 기능성 소재로의 개발이 가능하다. 그러나 유자씨의 플라보노이드는 다량의 지질과 혼재되어 있을 뿐만 아니라 플라보노이드가 배당체 형태로 존재하여 특유의 쓴맛을 나타내므로 식품에 사용하기는 어려운 점이 있어, 유자차 제조시 부산물로 대부분 사용되지 못하고 폐기되는 실정이다.In addition, the citron seeds account for 10 to 20% by weight of the citron weight, is rich in active ingredients such as bioflavonoids, limonoids, and also contains substances with antioxidant properties, and thus can be developed into various functional materials. However, not only the citron flavonoids are mixed with a large amount of lipids, but also flavonoids are present in glycosides and thus have a characteristic bitter taste, making them difficult to use in foods. .

한편, 콜라겐 활성 펩티드인 GHK는 글아이신(Gly)-히스티딘(His)-라이신(Lys)으로 구성된 트리 펩티드(tripeptide)로, 주로 조직을 보호하고 조직 손상에 따른 염증을 막아주는 것으로 알려져 있으며, 손상된 단백질을 재생시키는 과정과 손상조직을 정상조직으로 대체시키는 조직 재건축의 신호탄 역할을 한다. 또한, GHK에 구리가 결합된 Cu-GHK 역시 GHK와 유사한 콜라겐 생성 효과가 있는 것으로 알려져 있다. On the other hand, GHK, a collagen active peptide, is a tripeptide composed of Gly-Histidine (His) -Lysine (Lys), which is known to mainly protect tissues and prevent inflammation due to tissue damage. It serves as a signal for tissue rebuilding, in which protein is regenerated and damaged tissue is replaced with normal tissue. In addition, Cu-GHK in which copper is bound to GHK is also known to have a collagen production effect similar to that of GHK.

본 발명자들은 안전한 물질인 천연물 유래의 유자씨 오일과 콜라겐 활성 펩티드를 혼합하여 주름개선 효과를 보다 증진시키고자 하였다.The present inventors attempted to further enhance the effect of wrinkle improvement by mixing a citron seed oil and a collagen active peptide derived from a natural substance, which is a safe substance.

한편, 한국공개특허 제2009-0078202호에는 AHK, GHK 및 Cu-GHK로 이루어진 군에서 선택되는 어느 하나의 트리펩티드를 포함하는 피부 노화방지제가 개시되어 있으나, 본 발명의 유자씨 오일 및 콜라겐 활성 펩티드 혼합물을 유효성분으로 함유하는 피부 주름개선용 조성물은 개시된 바 없다.On the other hand, Korean Patent Publication No. 2009-0078202 discloses a skin anti-aging agent comprising any one of the peptides selected from the group consisting of AHK, GHK and Cu-GHK, citron oil and collagen active peptide of the present invention Skin wrinkle improvement composition containing the mixture as an active ingredient has not been disclosed.

본 발명은 유자씨 오일 및 콜라겐 활성 펩티드 혼합물을 유효성분으로 함유하는 피부 주름개선용 화장료 조성물에 관한 것이다.The present invention relates to a cosmetic composition for improving skin wrinkles containing a mixture of citron seed oil and collagen active peptide as an active ingredient.

본 발명의 콜라겐 활성 펩티드는 글아이신(Gly)-히스티딘(His)-라이신(Lys)으로 구성된 트리 펩티드(tripeptide)인 GHK 또는 구리가 추가 결합된 Cu-GHK이다. The collagen active peptide of the present invention is a tripeptide consisting of Gly-His-Lysine (Lys), GHK or Cu-GHK with copper further bound.

본 발명의 일 구현 예에서, 본 발명의 화장료 조성물은 당업계에서 통상적으로 제조되는 어떠한 제형으로도 제조될 수 있으며, 예를 들어, 용액, 현탁액, 유탁액, 페이스트, 겔, 크림, 로션, 파우더, 오일, 분말 파운데이션, 유탁액 파운데이션, 왁스 파운데이션 및 스프레이 등으로 제형화될 수 있고, 보다 상세하게는, 스킨, 스킨 소프트너, 스킨토너, 아스트린젠트, 로션, 밀크로션, 모이스쳐로션, 영양로션, 마사지크림, 영양크림, 아이 크림, 모이스쳐 크림, 핸드크림, 에센스, 영양에센스, 팩, 클렌징폼, 클렌징 워터, 클렌징 로션, 클렌징 크림, 바디로션, 바디클렌져, 비누 및 파우더의 화장품 제형으로 제조될 수 있으나 이에 한정하는 것은 아니다. In one embodiment of the present invention, the cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders , Oils, powder foundations, emulsion foundations, wax foundations, sprays, and the like, and more specifically, skins, skin softeners, skin toners, astringents, lotions, milk lotions, moisturizers, nutrition lotions, massages Cream, nutrition cream, eye cream, moisturizing cream, hand cream, essence, nutrition essence, pack, cleansing foam, cleansing water, cleansing lotion, cleansing cream, body lotion, body cleanser, soap and powder It is not limited to this.

본 발명의 화장료 조성물의 제형이 페이스트, 크림 또는 겔인 경우에는 담체 성분으로서 동물성유, 식물성유, 왁스, 파라핀, 전분, 트라칸트, 셀룰로오스 유도체, 폴리에틸렌 글리콜, 실리콘, 벤토나이트, 실리카, 탈크 또는 산화아연 등이 이용될 수 있다.When the formulation of the cosmetic composition of the present invention is a paste, cream or gel, the carrier component is animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide. This can be used.

본 발명의 화장료 조성물의 제형이 파우더 또는 스프레이인 경우에는 담체 성분으로서 락토스, 탈크, 실리카, 알루미늄 히드록시드, 칼슘 실리케이트 또는 폴리아미드 파우더가 이용될 수 있고, 특히 스프레이인 경우에는 추가적으로 클로로플루오로 히드로카본, 프로판/부탄 또는 디메틸 에테르와 같은 추진체를 포함할 수 있다.When the formulation of the cosmetic composition of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as the carrier component, and in particular, in the case of a spray, additionally chlorofluoro hydro Propellant such as carbon, propane / butane or dimethyl ether.

본 발명의 화장료 조성물의 제형이 용액 또는 유탁액인 경우에는 담체 성분으로서 용매, 용해화제 또는 유탁화제가 이용되고, 예컨대 물, 에탄올, 이소프로판올, 에틸 카보네이트, 에틸 아세테이트, 벤질 알코올, 벤질 벤조에이트, 프로필렌글리콜, 1,3-부틸글리콜 오일, 글리세롤 지방족 에스테르, 폴리에틸렌 글리콜 또는 소르비탄의 지방산 에스테르가 있다.When the formulation of the cosmetic composition of the present invention is a solution or emulsion, a solvent, solubilizing agent or emulsifying agent is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene. Fatty acid esters of glycol, 1,3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

본 발명의 화장료 조성물의 제형이 현탁액인 경우에는 담체 성분으로서 물, 에탄올 또는 프로필렌글리콜과 같은 액상의 희석제, 에톡실화 이소스테아릴 알코올, 폴리옥시에틸렌 소르비톨 에스테르 및 폴리옥시에틸렌 소르비탄 에스테르와 같은 현탁제, 미소결정성 셀룰로오스, 알루미늄 메타히드록시드, 벤토나이트, 아가 또는 트라칸트 등이 이용될 수 있다.When the formulation of the cosmetic composition of the present invention is a suspension, a liquid diluent such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester as carrier components , Microcrystalline cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

본 발명의 화장료 조성물에는 상기 유효성분 이외에 화장품 조성물에 통상적으로 이용되는 성분들을 포함하며, 예컨대 지방 물질, 유기 용매, 용해제, 농축제 및 겔화제, 연화제, 항산화제, 현탁화제, 안정화제, 발포제(foaming agent), 방향제, 계면활성제, 물, 이온형 또는 비이온형 유화제, 충전제, 금속이온 봉쇄제 및 킬레이트화제, 보존제, 비타민, 차단제, 습윤화제, 필수 오일, 염료, 안료, 친수성 또는 친유성 활성제, 지질 소낭과 같은 통상적인 보조제, 그리고 담체를 포함한다.The cosmetic composition of the present invention includes components conventionally used in cosmetic compositions in addition to the active ingredient, and include, for example, fatty substances, organic solvents, solubilizers, thickeners and gelling agents, softeners, antioxidants, suspending agents, stabilizers, foaming agents ( foaming agents), fragrances, surfactants, water, ionic or nonionic emulsifiers, fillers, metal ion sequestrants and chelating agents, preservatives, vitamins, blockers, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents , Conventional adjuvants such as lipid vesicles, and carriers.

또한, 본 발명은 유자씨 오일 및 콜라겐 활성 펩티드 혼합물을 유효성분으로 함유하는 피부 주름개선용 건강기능식품 조성물에 관한 것이다.The present invention also relates to a dietary supplement for skin wrinkles containing citron seed oil and collagen active peptide mixture as an active ingredient.

상기 건강기능식품 조성물은 분말, 과립, 환, 정제, 캡슐, 캔디, 시럽 및 음료의 제형으로 제조할 수 있으나 이에 제한되지 않는다. The dietary supplement composition may be prepared in the form of powders, granules, pills, tablets, capsules, candy, syrups and beverages, but is not limited thereto.

본 발명의 건강기능식품 조성물을 식품첨가물로 사용하는 경우, 상기 건강기능식품 조성물을 그대로 첨가하거나 다른 식품 또는 식품성분과 함께 사용될 수 있고, 통상적인 방법에 따라 적절하게 사용될 수 있다. 유효성분의 양은 그의 사용 목적에 따라 적절하게 사용될 수 있다. 일반적으로, 식품 또는 음료의 제조시 본 발명의 건강기능식품 조성물은 원료에 대하여 15 중량부 이하, 바람직하게는 10 중량부 이하의 양으로 첨가된다. 그러나 건강을 목적으로 장기간 섭취하는 경우에는 상기 양은 상기 범위 이하일 수 있으며, 안전성 면에서 아무런 문제가 없는 범위 내에서 상기 범위 이상의 양으로 사용될 수 있다.When the health functional food composition of the present invention is used as a food additive, the health functional food composition may be added as it is or used with other foods or food ingredients, and may be appropriately used according to a conventional method. The amount of the active ingredient may be appropriately used depending on the purpose of use thereof. In general, in the preparation of food or beverages, the nutraceutical composition of the present invention is added in an amount of 15 parts by weight or less, preferably 10 parts by weight or less with respect to the raw material. However, in the case of long-term intake for health purposes, the amount may be below the above range, and may be used in an amount above the above range within no problem in terms of safety.

상기 건강기능식품의 종류에 특별한 제한은 없다. 상기 건강기능식품 조성물을 첨가할 수 있는 식품의 예로는 육류, 소시지, 빵, 초콜릿, 캔디류, 스낵류, 과자류, 피자, 라면, 기타 면류, 껌류, 아이스크림류를 포함한 낙농제품, 각종 스프, 음료수, 차 드링크제, 알콜 음료 및 비타민 복합제 등이 있으며, 통상적인 의미에서의 건강식품을 모두 포함한다.There is no particular limitation on the type of dietary supplement. Examples of foods to which the health functional food composition may be added include meat, sausage, bread, chocolate, candy, snacks, confectionery, pizza, ramen, other noodles, gums, dairy products, including ice cream, various soups, drinks, tea Drinks, alcoholic beverages, vitamin complexes, and the like, and include all health foods in the conventional sense.

또한, 본 발명의 건강기능식품 조성물은 식품, 특히 기능성 식품으로 제조될 수 있다. 본 발명의 기능성 식품은 식품 제조 시에 통상적으로 첨가되는 성분을 포함하며, 예를 들어, 단백질, 탄수화물, 지방, 영양소 및 조미제를 포함한다. 예컨대, 드링크제로 제조되는 경우에는 유효성분 이외에 천연 탄수화물 또는 향미제를 추가 성분으로서 포함시킬 수 있다. 상기 천연 탄수화물은 모노사카라이드(예컨대, 글루코오스, 프럭토오스 등), 디사카라이드(예컨대, 말토스, 수크로오스 등), 올리고당, 폴리사카라이드(예컨대, 덱스트린, 시클로덱스트린 등) 또는 당알코올(예컨대, 자일리톨, 소르비톨, 에리쓰리톨 등)인 것이 바람직하다. 상기 향미제는 천연 향미제(예컨대, 타우마틴, 스테비아 추출물 등)와 합성 향미제(예컨대, 사카린, 아스파르탐 등)를 이용할 수 있다.In addition, the nutraceutical composition of the present invention may be prepared as a food, in particular a functional food. Functional foods of the present invention include ingredients that are commonly added in food production, and include, for example, proteins, carbohydrates, fats, nutrients and seasonings. For example, when prepared with a drink, natural carbohydrates or flavors may be included as additional ingredients in addition to the active ingredient. The natural carbohydrates may be monosaccharides (e.g. glucose, fructose, etc.), disaccharides (e.g. maltose, sucrose, etc.), oligosaccharides, polysaccharides (e.g., dextrins, cyclodextrins, etc.) or sugar alcohols (e.g. , Xylitol, sorbitol, erythritol and the like). The flavourant may be a natural flavourant (eg, taumartin, stevia extract, etc.) and a synthetic flavourant (eg, saccharin, aspartame, etc.).

상기 건강기능식품 조성물 이외에 여러 가지 영양제, 비타민, 전해질, 풍미제, 착색제, 펙트산 및 그의 염, 알긴산 및 그의 염, 유기산, 보호성 콜로이드 증점제, pH 조절제, 안정화제, 방부제, 글리세린, 알콜, 탄산음료에 사용되는 탄산화제 등을 더 함유할 수 있다. Various nutritional supplements, vitamins, electrolytes, flavors, coloring agents, pectic acid and salts thereof, alginic acid and salts thereof, organic acids, protective colloid thickeners, pH regulators, stabilizers, preservatives, glycerin, alcohols, carbonic acid Carbonation agent etc. which are used for a drink can be contained further.

Claims (1)

유자씨 오일 및 콜라겐 활성 펩티드 혼합물을 유효성분으로 함유하는 피부 주름개선용 화장료 조성물.Cosmetic composition for improving skin wrinkles containing a mixture of citron seed oil and collagen active peptide as an active ingredient.
KR1020180048820A 2018-04-27 2018-04-27 Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component KR20190124852A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020180048820A KR20190124852A (en) 2018-04-27 2018-04-27 Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020180048820A KR20190124852A (en) 2018-04-27 2018-04-27 Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component

Publications (1)

Publication Number Publication Date
KR20190124852A true KR20190124852A (en) 2019-11-06

Family

ID=68541580

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020180048820A KR20190124852A (en) 2018-04-27 2018-04-27 Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component

Country Status (1)

Country Link
KR (1) KR20190124852A (en)

Similar Documents

Publication Publication Date Title
JP4887499B2 (en) Active oxygen scavenger and moisturizer containing wild watermelon extract
KR20220164865A (en) Low molecule collagen peptide for anti-glycosylation and anti-aging in skin
KR101907921B1 (en) Composition for preventing or ameliorating skin wrinkle comprising Schisandra chinensis extract as effective component
KR20190125775A (en) Composition for promoting hair growth or preventing hair loss comprising oil from plant as effective component
KR20190124855A (en) Composition for skin anti-wrinkle effect comprising oil from plant and peptide for collagen activation as effective component
KR101914628B1 (en) Composition for skin anti-wrinkle effect comprising oil from plant as effective component
KR101474998B1 (en) Composition comprising extracts of white tea for the care of skin wrinkle
KR101914623B1 (en) Composition for moisturizing skin comprising oil from plant as effective component
KR20210119680A (en) Composition for enhancing skin barrier comprising eggshell membrane powder
KR101855989B1 (en) Method for producing buckwheat seed extract with increased effective component using water adding solubilizer as extraction solvent and buckwheat seed extract produced by the same
JP2006321730A (en) Antioxidant, antiaging agent, skin cosmetics, and food or drink
KR101907919B1 (en) Composition for preventing or improving skin wrinkle comprising Siraitia grosvenori residual extract as effective component
KR102406037B1 (en) Composition for antiaging comprising hydrolysates from Scomberomorus niphonius
KR102570987B1 (en) A composition comprising extract of Lilium hansonii
KR20190124852A (en) Composition for skin anti-wrinkle effect comprising citron seed oil and peptide for collagen activation as effective component
JP2004149729A (en) Antioxidant
KR20170078259A (en) Composition for improving skin conditions comprising Isosteviol
KR20160053192A (en) Cosmetic compositions comprising a Vin Chaud extract
KR20200064319A (en) Composition for skin anti-wrinkle comprising mixture of Ulmus davidiana var. japonica extract and Cornus officinalis extract as effective component
KR102299417B1 (en) Composition for inducing alteration of surrounding environment of a aged cell
KR101964967B1 (en) Composition for skin moisturizing comprising di-O-methyltetrahydrofuriguaiacin B as effective component
KR20190124853A (en) Composition for preventing hair loss or stimulating hair growth comprising citron seed oil and peptide for collagen activation as effective component
CN101543525A (en) Beauty composition containing vaccinium vitis-idaea extract and application thereof
KR101967919B1 (en) Composition for preventing, improving or treating skin wrinkle comprising hexane fraction of Clerodendrum trichotomum extract or compound isolated from Clerodendrum trichotomum extract as effective component
KR20170080069A (en) Composition for improving skin conditions comprising esculentoside A