KR20190065252A - 골 질환 치료용 PPARγ 작용제 - Google Patents

골 질환 치료용 PPARγ 작용제 Download PDF

Info

Publication number
KR20190065252A
KR20190065252A KR1020197007605A KR20197007605A KR20190065252A KR 20190065252 A KR20190065252 A KR 20190065252A KR 1020197007605 A KR1020197007605 A KR 1020197007605A KR 20197007605 A KR20197007605 A KR 20197007605A KR 20190065252 A KR20190065252 A KR 20190065252A
Authority
KR
South Korea
Prior art keywords
int131
subject
therapeutically effective
effective amount
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020197007605A
Other languages
English (en)
Korean (ko)
Inventor
데니스 랜피어
Original Assignee
인테크린 테라퓨틱스, 아이엔씨.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 인테크린 테라퓨틱스, 아이엔씨. filed Critical 인테크린 테라퓨틱스, 아이엔씨.
Publication of KR20190065252A publication Critical patent/KR20190065252A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
KR1020197007605A 2016-08-18 2017-08-18 골 질환 치료용 PPARγ 작용제 Ceased KR20190065252A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662376732P 2016-08-18 2016-08-18
US62/376,732 2016-08-18
PCT/US2017/047584 WO2018035449A1 (en) 2016-08-18 2017-08-18 Pparϒ agonist for treatment of bone disorders

Publications (1)

Publication Number Publication Date
KR20190065252A true KR20190065252A (ko) 2019-06-11

Family

ID=61197122

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197007605A Ceased KR20190065252A (ko) 2016-08-18 2017-08-18 골 질환 치료용 PPARγ 작용제

Country Status (11)

Country Link
US (1) US20190167660A1 (enExample)
EP (1) EP3500269A4 (enExample)
JP (2) JP2019524889A (enExample)
KR (1) KR20190065252A (enExample)
CN (1) CN109843292A (enExample)
AU (1) AU2017313842A1 (enExample)
BR (1) BR112019003133A2 (enExample)
CA (1) CA3033971A1 (enExample)
EA (1) EA201990513A1 (enExample)
SG (2) SG10202101500WA (enExample)
WO (1) WO2018035449A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107683135A (zh) 2015-03-09 2018-02-09 因特克林医疗有限公司 用于治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy
JP2024013883A (ja) * 2022-07-21 2024-02-01 株式会社三洋物産 遊技機
JP2024013885A (ja) * 2022-07-21 2024-02-01 株式会社三洋物産 遊技機
JP2024013886A (ja) * 2022-07-21 2024-02-01 株式会社三洋物産 遊技機

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL357678A1 (en) * 2000-04-28 2004-07-26 Sankyo Company, Limited Ppargamma modulators
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
CA2555914A1 (en) * 2004-03-08 2005-09-22 Amgen Inc. Therapeutic modulation of ppar (gamma) activity
HK1218510A1 (zh) * 2013-01-30 2017-02-24 Intekrin Therapeutics, Inc. 用於治療多發性硬化症的PPARγ激動劑
PL3203999T3 (pl) * 2014-10-10 2020-07-27 Liminal Biosciences Limited Podstawione związki aromatyczne i kompozycje farmaceutyczne do zapobiegania i leczenia osteoporozy

Also Published As

Publication number Publication date
AU2017313842A1 (en) 2019-03-07
US20190167660A1 (en) 2019-06-06
CN109843292A (zh) 2019-06-04
SG11201901328VA (en) 2019-03-28
EP3500269A1 (en) 2019-06-26
JP2019524889A (ja) 2019-09-05
EP3500269A4 (en) 2020-04-15
CA3033971A1 (en) 2018-02-22
JP2022116294A (ja) 2022-08-09
WO2018035449A1 (en) 2018-02-22
EA201990513A1 (ru) 2019-08-30
BR112019003133A2 (pt) 2019-05-21
SG10202101500WA (en) 2021-03-30

Similar Documents

Publication Publication Date Title
Henriksen et al. Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2
JP2022116294A (ja) 骨疾患の治療のためのPPARγアゴニスト
RU2746000C2 (ru) Состав для ингибирования образования агонистов 5-ht2b и способы его применения
Orwoll et al. Evaluation of teriparatide treatment in adults with osteogenesis imperfecta
JP5984674B2 (ja) サイトカインアンタゴニスト及びコルチコステロイドを有する併用製剤
JP2018162321A (ja) X連鎖副腎白質ジストロフィーの処置におけるソベチロムの使用
JP2557779B2 (ja) 2成分型骨粗鬆症用薬剤
Conover et al. Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis
John et al. AXT914 a novel, orally-active parathyroid hormone-releasing drug in two early studies of healthy volunteers and postmenopausal women
Xu et al. Effects of different dosages of parathyroid hormone-related protein 1–34 on the bone metabolism of the ovariectomized rat model of osteoporosis
JP3771280B2 (ja) オステオポローシスの治療方法およびそのための組成物
Wensel et al. Effects of denosumab on bone mineral density and bone turnover in postmenopausal women
US20050032698A1 (en) Stabilized formulation of parathyroid hormone
Ebeling et al. Teriparatide (rhPTH 1–34) for the treatment of osteoporosis
JP2020530031A (ja) 前立腺癌治療における新しいアジュバント療法
JP2005526022A5 (ja) 関節リウマチの処置
JP6279529B2 (ja) 虚弱を治療する方法
Cosman Parathyroid hormone and abaloparatide treatment for osteoporosis
Cosman Teriparatide and abaloparatide treatment for osteoporosis
CN114096269A (zh) 高浓度胰岛素制剂
El Miedany Geroscience and management of osteoporosis in older adults
Dejaeger et al. Pharmacological treatment of osteoporosis in older patients
Nass et al. Growth hormone supplementation in the elderly
Klipping et al. Mireille GF Gerrits, Pharm. D., Hester Kramer, Ph. D., Rachid el Galta, Ph. D., Geertje van Beerendonk, Ph. D., Rob Hanssen, Ph. D., Khalid Abd-Elaziz, MD, c
Cusano et al. Newer Adult Bone Drugs

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20190315

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20200818

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20221205

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20230211

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20221205

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I