CA3033971A1 - Ppar.gamma. agonist for treatment of bone disorders - Google Patents

Ppar.gamma. agonist for treatment of bone disorders Download PDF

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Publication number
CA3033971A1
CA3033971A1 CA3033971A CA3033971A CA3033971A1 CA 3033971 A1 CA3033971 A1 CA 3033971A1 CA 3033971 A CA3033971 A CA 3033971A CA 3033971 A CA3033971 A CA 3033971A CA 3033971 A1 CA3033971 A1 CA 3033971A1
Authority
CA
Canada
Prior art keywords
subject
int131
therapeutically effective
effective amount
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3033971A
Other languages
English (en)
French (fr)
Inventor
Dennis Lanfear
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intekrin Therapeutics Inc
Original Assignee
Intekrin Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intekrin Therapeutics Inc filed Critical Intekrin Therapeutics Inc
Publication of CA3033971A1 publication Critical patent/CA3033971A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
CA3033971A 2016-08-18 2017-08-18 Ppar.gamma. agonist for treatment of bone disorders Pending CA3033971A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662376732P 2016-08-18 2016-08-18
US62/376,732 2016-08-18
PCT/US2017/047584 WO2018035449A1 (en) 2016-08-18 2017-08-18 Pparϒ agonist for treatment of bone disorders

Publications (1)

Publication Number Publication Date
CA3033971A1 true CA3033971A1 (en) 2018-02-22

Family

ID=61197122

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3033971A Pending CA3033971A1 (en) 2016-08-18 2017-08-18 Ppar.gamma. agonist for treatment of bone disorders

Country Status (11)

Country Link
US (1) US20190167660A1 (enExample)
EP (1) EP3500269A4 (enExample)
JP (2) JP2019524889A (enExample)
KR (1) KR20190065252A (enExample)
CN (1) CN109843292A (enExample)
AU (1) AU2017313842A1 (enExample)
BR (1) BR112019003133A2 (enExample)
CA (1) CA3033971A1 (enExample)
EA (1) EA201990513A1 (enExample)
SG (2) SG10202101500WA (enExample)
WO (1) WO2018035449A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107683135A (zh) 2015-03-09 2018-02-09 因特克林医疗有限公司 用于治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy
JP2024013883A (ja) * 2022-07-21 2024-02-01 株式会社三洋物産 遊技機
JP2024013885A (ja) * 2022-07-21 2024-02-01 株式会社三洋物産 遊技機
JP2024013886A (ja) * 2022-07-21 2024-02-01 株式会社三洋物産 遊技機

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL357678A1 (en) * 2000-04-28 2004-07-26 Sankyo Company, Limited Ppargamma modulators
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
CA2555914A1 (en) * 2004-03-08 2005-09-22 Amgen Inc. Therapeutic modulation of ppar (gamma) activity
HK1218510A1 (zh) * 2013-01-30 2017-02-24 Intekrin Therapeutics, Inc. 用於治療多發性硬化症的PPARγ激動劑
PL3203999T3 (pl) * 2014-10-10 2020-07-27 Liminal Biosciences Limited Podstawione związki aromatyczne i kompozycje farmaceutyczne do zapobiegania i leczenia osteoporozy

Also Published As

Publication number Publication date
AU2017313842A1 (en) 2019-03-07
US20190167660A1 (en) 2019-06-06
CN109843292A (zh) 2019-06-04
SG11201901328VA (en) 2019-03-28
EP3500269A1 (en) 2019-06-26
JP2019524889A (ja) 2019-09-05
EP3500269A4 (en) 2020-04-15
JP2022116294A (ja) 2022-08-09
WO2018035449A1 (en) 2018-02-22
EA201990513A1 (ru) 2019-08-30
KR20190065252A (ko) 2019-06-11
BR112019003133A2 (pt) 2019-05-21
SG10202101500WA (en) 2021-03-30

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Effective date: 20220817