KR20190046144A - Method of manufacturing food additive - Google Patents
Method of manufacturing food additive Download PDFInfo
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- KR20190046144A KR20190046144A KR1020170139367A KR20170139367A KR20190046144A KR 20190046144 A KR20190046144 A KR 20190046144A KR 1020170139367 A KR1020170139367 A KR 1020170139367A KR 20170139367 A KR20170139367 A KR 20170139367A KR 20190046144 A KR20190046144 A KR 20190046144A
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- food additive
- bean
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Images
Classifications
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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Abstract
Description
본 발명은 한방소재가 조합된 식품 첨가물의 제조방법 및 상기 방법으로 제조된 식품 첨가물에 관한 것으로서, 보다 상세하게는 유근피, 차조기, 나복자, 병풍 등을 포함하는 한방소재 혼합물을 발효 후 농축 추출한 다음 나노처리하여 식품 첨가물을 제조하는 방법, 및 상기 방법으로 나노화되어 항균 및 소화력이 향상된 식품 첨가물에 관한 것이다.More particularly, the present invention relates to a method for producing a food additive in which a one-sided material is combined and a food additive prepared by the method. More particularly, the present invention relates to a method for producing a food additive, And a food additive which is nanoized by the above method and has improved antibacterial and digestive power.
한약재는 일반적으로 탕제의 형태로 이용된다. 탕제는 보통 용기에 약재와 정제수를 혼합하여 넣은 후 가열하여 한약재가 우러난 약물을 일컫는다. 이러한 탕제는 한약재를 가열처리하여 조제되므로 유효성분의 추출이 용이할 뿐만 아니라 흡수되기 쉽고, 부작용이 적으며, 반응이 빠르다. 그러나 이러한 탕제는 한의사나 한약사로부터 직접 처방을 받아 조제하고 있으므로, 처방비 및 조제비 등이 상당히 고가여서 경제적인 부담이 커 대중화하기엔 많은 어려움이 있다.Herbal medicines are generally used in the form of herbal medicines. It is a medicinal herb that is mixed with medicinal materials and purified water in a container and then heated to heat up the herbal medicines. Since the herbal medicines are prepared by heating the herbal medicines, the active ingredients are easily extracted and easily absorbed, the side effects are small, and the reaction is fast. However, since such medicine is prepared directly from oriental medicine or herbal medicine, prescription fee and preparation cost are very expensive, and there is a great deal of economic burden and it is difficult to popularize it.
이와 같은 단점을 해결하기 위해서는 추출물(extracts)을 이용한 엑스제가 개발되었다. 엑스제란 한약재를 물 등의 용매로 추출하고 추출액을 전부 또는 대부분 농축, 건조하여 반고체 또는 고체형으로 만든 제제를 말한다. 그러나 종래의 엑스제는 부피가 작고, 사용하기 편리한 장점이 있다. 그러나 이런 엑스제도 상기 탕제와 마찬가지로 한의사나 한약사 등의 받아 조제하고 있으므로 이를 대중화하기엔 어려움이 있고, 한약재 성분 특유의 냄새를 제거할 수 없어 일반식품과는 별도로 복용하여야 하므로 일상생활에서 정기적으로 이를 섭취하기에는 많은 불편함이 있다. 또한, 상기 엑스제는 모두 한약재라는 선입견이 강해 복용하는 사람에 따라 특히 어린이들이나 비위가 약한 사람에게는 복용, 섭취에 상당한 거부감을 느끼게 되는 문제점이 있다.Extracts have been developed to solve these drawbacks. Exogen is a preparation made by extracting herbal medicines with a solvent such as water and concentrating all or most of the extract solution and drying it into semi-solid or solid form. However, the conventional extrusion is advantageous in that it is small in volume and easy to use. However, since the X-ray system is similar to the above-mentioned tablet, it is difficult to popularize it because it is prepared by taking a Chinese medicine or Chinese medicine, etc., and since it can not remove the characteristic odor of herbal medicine ingredient, it should be taken separately from general food. Therefore, There are a lot of inconveniences. In addition, all of the above-mentioned agents have a preconceived notion that they are herbal medicines.
이에, 한약재를 일상생활에서도 편리하게 복용가능하고, 일반 조미료와 같은 방법으로 일반식품에 첨가하여 복용하게 함으로써, 누구든지 어느 때나 부담감을 느끼지 않고 한방소재의 효능과 기능을 갖는 음식물을 섭취할 수 있게 하기 위한 한방소재 식품첨가제 및 한방소재 기능성 식품을 개발하는 것이 요구된다.Accordingly, the herb medicine can be conveniently taken in everyday life, and can be added to the general food in the same manner as a general seasoning, so that anyone can take food with the effect and function of herbal ingredients without any burden at any time It is required to develop a one-component food additive and a one-component functional food.
한편, 아토피 피부염(atopic dermatitis)이란 아토피성 체질인 사람에게 일어나는 가려움이 매우 심한 습진이다. 아토피 피부염은 유발원인이 아직까지 확실하게 규명되지 못한 유전적 질환으로서, 그 발증과 악화에는 환경인자가 크게 관여하고 있는 것으로 알려져 있다. 그 외에 건조한 피부, 정상인에 비해 쉽게 피부 가려움증을 느끼는 특성, 세균·바이러스·곰팡이 등에 의한 감염, 정서적 요인, 환경적 요인 등이 서로 복합적으로 작용하여 일어나는 것으로 보인다. 최근 수십년 동안 발병률이 상승하고 있으며, 우리나라 또한 그 환자수가 크게 늘고 있는 현실이다.On the other hand, atopic dermatitis (atopic dermatitis) is a very severe itching that occurs in people with atopic dermatitis. Atopic dermatitis is a genetic disorder in which the cause of the disease has not yet been clearly identified. It is known that environmental factors are involved in the onset and deterioration of the disease. In addition, it seems to occur due to the combination of dry skin, the characteristics of skin itching easily compared with normal people, infections caused by bacteria, viruses, molds, emotional factors, and environmental factors. In recent decades, the incidence has been rising, and the number of patients in Korea is increasing.
종래의 아토피성 피부염 관련 기능성 식품 등에 관련된 한방소재 관련 기술로는, 한국특허공개 제2006-0058530호에 가려움증 완화 효과를 나타내는 우엉, 신이화, 엉겅퀴, 울금, 오미자의 혼합 추출물이 기재되어 있고, 한국특허공개 제2007-0095588호에 아토피성 피부질환 치료용 특수 한방 조성물 및 그 제조공법에 관한 금은화를 포함하는 어성초, 당귀, 약쑥, 천궁, 신선초, 홰나무, 솔싹, 박하, 녹두, 살구씨, 송진, 상황버섯, 생강, 현삼, 조피, 녹차, 금잔화, 도라지, 검은콩의 조성물이 기재되어 있고, 한국특허공개 제2006-0074038호에 아토피성 피부염의 예방효과를 가지는 조성물에 금은화, 당귀, 부평초, 우슬, 금잔화, 알로에, 황금의 혼합추출물이 기재되어 있고, 한국특허공개 제2006-0092373호에 화분, 백강잠, 동충하초, 사상자를 주성분으로 하고, 선택적 성분으로서 금은화, 질려, 사삼, 또는 포공영을 더욱 포함하는 조성물로서 소아 아토피 피부염의 예방 및 개선작용이 기재되어 있고, 한국특허공개 제2007-0110589호에는 쑥에서 분리된 산성 다당류를 함유하는 피부여드름 간균과 아토피 황색 포도상 구균의 인체 세포결합 저해용 조성물의 적용이 기재되어 있고, 한국 특허공개 제2001-0003116호에는 청자소엽과 적자소엽의 물 추출액과 소금을 포함하는 아토피성 피부염 치료용 기능성 식품이 기재되어 있다.Korean Patent Laid-Open Publication No. 2006-0058530 discloses a mixed extract of burdock, Shinhwa, thistle, urogum, and omija, which exhibits an itching relieving effect, in Korean Patent Application No. 2006-0058530, which is related to conventional oriental ingredients related to functional foods related to atopic dermatitis. Japanese Patent Application Laid-Open No. 2007-0095588 discloses a specific herbal composition for treating atopic skin diseases and a method for producing the herb composition comprising at least one selected from the group consisting of Ganoderma lucidum, Angelica gigas, Angelica keiskei koidz., Astragalus membranaceus, Mushroom, ginger, ginseng, joppy, green tea, marigold, bellflower, black bean, and Korean Patent Publication No. 2006-0074038 discloses a composition having a preventive effect against atopic dermatitis, A mixture of marigold, aloe, and gold is disclosed. In Korean Patent Laid-Open Publication No. 2006-0092373, pollen, white mackerel, caterpillar fungus, and casualties are the main components, Korean Patent Laid-Open No. 2007-0110589 discloses a composition for preventing and improving pediatric atopic dermatitis as a composition further comprising ginseng, ginger, ginseng, or porphyry. In Korean Patent Publication No. 2007-0110589, a skin acne bacterium containing an acidic polysaccharide isolated from mugwort Korean Patent Laid-Open Publication No. 2001-0003116 discloses a functional food for the treatment of atopic dermatitis, which comprises a celia lobule, a water extract of defoliated lobules, and salt, have.
상기 한방소재들은 그 효과가 단시간 내에 나타나 효과가 미미하여 사용하기 부적절하였다. 또한, 기존의 의학적 처방제인 스테로이드제에는 여러 가지 부작용도 나타나고 있으므로, 이러한 문제를 해소시키기 위해서는 아토피 피부염 증상을 줄이면서 부작용 없이 안심하고 사용할 수 있는 새로운 한방소재 조성물 개발이 절실히 요구되는 있는 실정이다.The above-mentioned one-way materials were inadequate to use because their effects appeared in a short time and their effect was negligible. In addition, since steroid drugs, which are conventional medical prescription drugs, exhibit various side effects, there is a desperate need to develop a new herbal composition which can reduce the symptoms of atopic dermatitis and reliably use without any side effects.
본 발명의 목적은 유근피(또는 차가버섯, 제비콩), 차조기(또는 표고버섯, 포공영), 나복자(또는 산사, 맥아, 우방자) 및 병풍(또는 황정, 옥죽) 등의 여러 가지 기능과 효과를 갖는 다수의 한방재료를 혼합하여 발효 농축 추출한 후, 나노처리함으로써, 항균 등의 한방소재의 기능을 향상시키고, 소화력을 향상시키는 효과를 갖는 나노화된 한방소재 식품첨가제 및 이의 제조방법을 제공하는데 그 목적이 있다.It is an object of the present invention to provide a method and apparatus for the production of a variety of products having various functions and effects such as yugi (or chaga mushroom, lotus beans), chaga (or shiitake mushroom, It is an object of the present invention to provide a nanoized one-component food additive having a function of enhancing the function of a herbal ingredient such as antibacterial agent by mixing and culturing a large number of herbal materials, have.
본 발명의 또다른 목적은 유근피(또는 차가버섯, 제비콩), 차조기(또는 표고버섯, 포공영), 나복자(또는 산사, 맥아, 우방자) 및 병풍(또는 황정, 옥죽) 등의 기능성 한방소재들을 일반 조미료와 같은 방법으로 일반식품에 첨가하여 복용하게 함으로써, 누구든지 어느 때나 부담감을 느끼지 않고 상기 한방소재들의 향상된 효능 및 소화력을 갖는 음식물을 섭취할 수 있게 하기 위한 나노화된 한방소재 식품첨가제 및 이의 제조방법을 제공하는데 그 목적이 있다.Another object of the present invention is to provide functional herbal materials such as yugi (or chaga mushroom, lotus bean), chaga (or shiitake mushroom, porcupine), napalm (or hermaphrodite, malt, The present invention relates to a food additive for nano-sized herbal ingredients and a method for producing the same, in which a food having improved potency and digestive power of the herbal ingredients can be consumed without any burden at any time by allowing them to be added to ordinary foods in the same manner as a seasoning The purpose is to provide.
상기 목적을 달성하기 위하여, 본 발명은 In order to achieve the above object,
유근피, 차가버섯 및 제비콩으로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제1 소재; 차조기, 표고버섯 및 포공영으로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제2 소재; 나복자, 산사, 맥아 및 우방자로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제3 소재; 및, 병품, 황정 및 옥죽으로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제4 소재;를 혼합 및 발효하는 제1 단계;A first material comprising at least one selected from the group consisting of carnauba, rhizome, and bean curd; A second material comprising at least one selected from the group consisting of a shaker, a shiitake mushroom and a porpoise; A third material comprising at least one selected from the group consisting of napkins, hornbills, malt, and strangers; And a fourth material containing at least one selected from the group consisting of a pathogen, a hornbeam, and an oak seed;
상기 제1 단계에서 얻어진 발효 처리된 혼합소재를 농축 추출하는 제2 단계; A second step of concentrating and extracting the fermented mixed material obtained in the first step;
상기 제2 단계에서 얻어진 농축 추출물을 동결건조하여 분말을 얻는 제3 단계;A third step of lyophilizing the concentrated extract obtained in the second step to obtain a powder;
상기 제3 단계에서 얻어진 농축 추출물을 나노처리하여 용액을 얻는 제4 단계; 및A fourth step of nano-treating the concentrated extract obtained in the third step to obtain a solution; And
상기 제3 단계에서 얻어진 동결건조 분말 및 상기 제4 단계에서 얻어진 나노처리용액을 혼합하는 단계를 포함하는 식품 첨가물의 제조방법을 제공한다.And a step of mixing the lyophilized powder obtained in the third step and the nanoprocessed solution obtained in the fourth step.
또한, 본 발명은 상기 본 발명에 따른 제조방법에 따라 제조된 식품 첨가물을 제공한다.The present invention also provides a food additive prepared according to the process of the present invention.
또한, 본 발명은 상기 본 발명에 따른 식품 첨가물을 포함하는 천연 기능성 식품을 제공한다.The present invention also provides a natural functional food comprising the food additive according to the present invention.
아울러, 본 발명은 상기 본 발명에 따른 식품 첨가물을 유효성분으로 함유하는 아토피를 포함한 염증성 피부질환 개선 또는 완화용 건강식품을 제공한다.In addition, the present invention provides a health food for improving or alleviating inflammatory skin diseases, including atopic diseases, containing the food additive according to the present invention as an active ingredient.
본 발명에 따른 한방소재가 조합된 식품 첨가제, 그 제조 방법과 이를 첨가한 천연 기능성 식품은 다음과 같은 효과가 있다.The food additives according to the present invention in combination with herbal ingredients, the production method thereof, and the natural functional foods to which they are added have the following effects.
(1) 한방 소재로 식품 첨가제를 제조하므로, 인체 안에서 생길 수 있는 부작용을 최소화할 수 있다.(1) Since the food additive is manufactured from herbal ingredients, the side effects that may occur in the human body can be minimized.
(2) 한방 소재를 저분자로 제조하여 사용하므로, 위장의 자극을 최소화할 수있을 뿐만 아니라 위장에서 쉽게 소화 흡수가 이루어지게 하여 위장의 부담을 줄이면서 장막 보호화 장내 환경의 정상화를 유도하여 아토피 등 염증성 피부질환에 유효하게 작용한다.(2) Since the herbal material is manufactured by using low-molecular material, it can minimize stomach irritation and easily digestion and absorption in the stomach, thereby reducing the burden of stomach and inducing normalization of the intestinal protective environment. It is effective for inflammatory skin diseases.
(3) 한방 소재로 식품 첨가제를 제조할 때나 식품을 제조할 때 해양 심층수를 사용하므로, 해양 심층수에 함유된 4대 필수미네랄을 인체에 함께 공급할 수 있어 인체에서의 알레르기 반응과 가려움 유발을 줄일 수 있다.(3) It is possible to supply the four essential minerals contained in deep seawater to the human body, so that allergic reaction and itching induction in the human body can be reduced. have.
(4) 또한, 이처럼 저분자 형태로 이루어진 영양성분은 소화 흡수를 빠르게 하여 위장에 부담을 줄일 뿐 아니라 에너지 대사에 도움을 주어 만성 피로를 개선하는데 유효하다.(4) In addition, the nutritional ingredient made in the form of low molecular weight not only reduces burden on the stomach by accelerating digestion and absorption, but also helps to improve energy metabolism, thereby improving chronic fatigue.
도 1은 본 발명의 따른 식품첨가물의 아토피 피부염에 대한 증상 완화 효과를 확인하기 위해, 11세 남자 청소년을 대상으로 한 복용 전후 임상시험 사진이다.
도 2는 본 발명의 따른 식품첨가물의 아토피 피부염에 대한 증상 완화 효과를 확인하기 위해, 63세 남자 노인을 대상으로 한 복용 전후 임상시험 사진이다.FIG. 1 is a photograph of an 11-year-old male adolescent before and after the administration of a food additive according to the present invention in order to confirm the symptom relief effect on atopic dermatitis.
FIG. 2 is a photograph of a 63-year-old male patient before and after the administration of the food additive according to the present invention in order to confirm the symptom relief effect on atopic dermatitis.
이하, 본 발명을 상세히 설명한다.Hereinafter, the present invention will be described in detail.
본 명세서 및 청구범위에 사용된 용어나 단어는 통상적이거나 사전적인 의미로 한정해서 해석되어서는 안 되며, 발명자는 그 자신의 발명을 최고의 방법으로 설명하기 위해 용어의 개념을 적절하게 정의할 수 있다는 원칙에 따라 본 발명의 기술적 사상에 부합하는 의미와 개념으로 해석되어야만 한다.The terms and words used in the present specification and claims should not be construed as limited to ordinary or preliminary meaning and the inventor can define the concept of a term appropriately to describe its own invention in the best way Should be construed in accordance with the meaning and concept consistent with the technical idea of the present invention.
따라서 본 명세서에 기재된 실시예와 도면에 도시된 구성은 본 발명의 가장 바람직한 일 실시예에 불과할 뿐이고 본 발명의 기술적 사상을 모두 대변하는 것은 아니므로, 본 출원 시점에서 이들을 대체할 수 있는 다양한 균등물과 변형례가 있을 수 있음을 이해하여야 한다.Therefore, the embodiments described in the present specification and the configurations shown in the drawings are merely the most preferred embodiments of the present invention and are not intended to represent all of the technical ideas of the present invention. Thus, various equivalents And variations may be present.
본 발명은 The present invention
유근피, 차가버섯 및 제비콩으로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제1 소재; 차조기, 표고버섯 및 포공영으로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제2 소재; 나복자, 산사, 맥아 및 우방자로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제3 소재; 및, 병품, 황정 및 옥죽으로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제4 소재;를 혼합 및 발효하는 제1 단계;A first material comprising at least one selected from the group consisting of carnauba, rhizome, and bean curd; A second material comprising at least one selected from the group consisting of a shaker, a shiitake mushroom and a porpoise; A third material comprising at least one selected from the group consisting of napkins, hornbills, malt, and strangers; And a fourth material containing at least one selected from the group consisting of a pathogen, a hornbeam, and an oak seed;
상기 제1 단계에서 얻어진 발효 처리된 혼합소재를 농축 추출하는 제2 단계; A second step of concentrating and extracting the fermented mixed material obtained in the first step;
상기 제2 단계에서 얻어진 농축 추출물을 동결건조하여 분말을 얻는 제3 단계;A third step of lyophilizing the concentrated extract obtained in the second step to obtain a powder;
상기 제3 단계에서 얻어진 농축 추출물을 나노처리하여 용액을 얻는 제4 단계; 및A fourth step of nano-treating the concentrated extract obtained in the third step to obtain a solution; And
상기 제3 단계에서 얻어진 동결건조 분말 및 상기 제4 단계에서 얻어진 나노처리용액을 혼합하는 단계를 포함하는 식품 첨가물의 제조방법을 제공한다.And a step of mixing the lyophilized powder obtained in the third step and the nanoprocessed solution obtained in the fourth step.
상기 제조방법에 있어서, 상기 단계 1)에서 제1 소재, 제2 소재, 제3 소재 및 제4 소재의 함량은 각각 전체 혼합물 100 중량부 대비, 30 내지 50 중량부, 10 내지 30 중량부, 5 내지 15 중량부, 및 0.5 내지 5 중량부인 것이 바람직하다.In the above manufacturing method, the content of the first material, the second material, the third material and the fourth material in the step 1) is 30 to 50 parts by weight, 10 to 30 parts by weight, 5 to 30 parts by weight, To 15 parts by weight, and from 0.5 to 5 parts by weight.
상기 혼합물은 영지버섯, 지황, 당귀, 작약, 석창포, 소합향, 녹용, 생강, 계지 및 아가리쿠스로 구성된 군으로부터 선택된 하나 또는 둘 이상을 포함하는 제5 소재를 더 포함할 수 있다. 이때, 상기 제5 소재의 함량은 전체 혼합물 100 중량부 대비, 0.1 내지 10 중량부인 것이 바람직하다.The mixture may further comprise a fifth material comprising one or more selected from the group consisting of Ganoderma lucidum, Rhizoma, Angelica keiskei, Peony root, Seokchangpo, Soybean, Deer, Ginger, Seed and Agaricus. At this time, the content of the fifth material is preferably 0.1 to 10 parts by weight relative to 100 parts by weight of the whole mixture.
상기 혼합물은 어성초, 삼백초, 인삼, 황기, 감초, 봉밀, 창이자, 용안육, 신국, 곡아, 상엽, 국화, 갈근, 근대, 대황, 차가버섯, 자소엽, 백지, 녹차, 동충하초, 차조기, 사상자, 토사자, 호도인, 합개, 황금, 대황, 대두황권, 백합, 맥문동, 구기자, 상심자 ,흑지마, 육계, 호초, 소회향, 향유, 감초, 진창미, 율무(의이인), 팥(적소두), 복령, 옥미수, 택사 및 동과피로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제6 소재를 더 포함할 수 있다. 이때, 상기 제6 소재의 함량은 전체 혼합물 100 중량부 대비, 0.1 내지 10 중량부인 것이 바람직하다.The mixture contains at least one compound selected from the group consisting of Rhizoctonia spp., Saururus chinensis, Ginseng, Hwanggi, Licorice, Bongil, Changjia, Yonggak, New country, (Red pepper), red bean (red pepper), red pepper, red lentil, red lentil, red lentil, black lentil, broiler, And a sixth material including at least one selected from the group consisting of oxime, oxazole, phthalocyanine, copper and copper. At this time, the content of the sixth material is preferably 0.1 to 10 parts by weight based on 100 parts by weight of the whole mixture.
상기 한방소재 혼합물은 발효 전에 세척, 절단 및 건조하는 것이 바람직하며, 이때 한방소재를 깨끗하게 씻어서 미리 정한 크기, 예를 들어서 5 ~ 10 ㎜로 잘라서 후술할 발효 후 추출 과정에서 추출 효과를 높일 수 있게 하는 것이 바람직하다.It is preferable to wash, cut and dry the mixture before the fermentation. In this case, the one-side material may be cleaned and cut to a predetermined size, for example, 5 to 10 mm to increase the extraction effect in the extraction process after the fermentation .
상기 한방소재 혼합물은 발효 전에 살균하는 것이 바람직하며, 한방소재를 미리 정한 온도에서 미리 정한 시간 동안 살균 소독하는 것이 바람직하다. 이때, 살균 온도는 대부분의 미생물과 세균을 제거할 수 있는 온도 예를 들어서 60 ~ 110℃ 온도 범위에서 이루어지게 하고, 이때의 살균 시간은 0.5 ~ 2시간 동안 살균하는 것이 바람직하고, 버섯류는 저온 60℃ 이하 저온살균, 한방소재는 105℃ 1시간 이상 살균하는 것이 바람직하다.It is preferable that the one-way material mixture is sterilized before fermentation, and the one-way material is preferably sterilized at a predetermined temperature for a predetermined time. At this time, the sterilization temperature is set at a temperature at which most microorganisms and bacteria can be removed, for example, at a temperature range of 60 to 110 DEG C, and sterilization time is preferably sterilized for 0.5 to 2 hours, ℃ pasteurization, one-sided material is preferably sterilized for more than one hour at 105 ℃.
상기 제조방법에 있어서, 상기 단계 1)에서 혼합 후 자연발효시키는 것이 바람직하다. 이때, 발효를 위해 살균 소독한 천연 소재에 혼합 유산균주를 접종한다. 여기서, 혼합 유산균주는 당류를 발효하여 에너지를 획득하고 다량의 락트산을 생성하는 통상의 세균주를 혼합한 것으로, 예를 들어서 유산간균, 유산구균, 및 비피더스균 중에서 적어도 하나 이상을 포함하게 구성할 수 있으며, 특히 락토바실러스 속의 루테리 및 플란타럼, 비피도박테리움 속의 락티스 및 인판티스를 포함한 12종의 혼합균주를 발효 접종균으로 사용하는 것이 바람직하다. 이때, 자연 발효는 혼합 유산균주가 발효할 수 있는 조건, 예를 들어서 37 ~ 42℃ 온도에서 22 ~ 26시간 동안 자연 발효하게 한다.In the above-mentioned production method, it is preferable to naturally ferment after mixing in step 1). At this time, mixed lactic acid bacteria are inoculated into a natural material sterilized for fermentation. Herein, the mixed lactic acid bacteria is a mixture of common bacterial strains which ferment a saccharide to obtain energy and produce a large amount of lactic acid. For example, it may comprise at least one of lactic acid bacterium, lactic acid bacteria and bifid bacteria In particular, it is preferable to use 12 kinds of mixed strains including Lacterium and Plutarum in Lactobacillus genus, Lactis and Phosphatus in Bifidobacterium as fermentation inoculum. At this time, the natural fermentation is carried out under the condition that the mixed lactic acid bacteria can ferment, for example, at 37 to 42 ° C for 22 to 26 hours.
상기 발효는 혼합 유산균주에 효모 건조물, 당화균(고초균), 라이조(황국균), 김치스티터(MG865), 브루어스 이스트파우터(맥주효모) 및 클로렐라균를 혼합하여 사용될 수 있다.The fermentation can be carried out by mixing a yeast product, a saccharification bacteria (Bacillus subtilis), a rizoo (Hwang Kuk-gyun), Kimchi steer (MG865), a brewers yeast paste (brewer's yeast) and chlorella.
상기 발효는 체리세이지, 감국, 원추리, 달맞이, 민들레 또는 익모초 중 어느 하나 이상을 포함하는 자연발효액을 더 첨가하여 발효시킬 수 있다.The fermentation can be carried out by adding a natural fermentation broth containing at least one of cherry sage, ham, gruel, moon cake, dandelion or motherwort.
상기 제조방법에 있어서, 상기 단계 2)는 추출물을 얻는 단계이다. 이때, 추출 조건은 한방소재에 함유된 유효 성분을 충분히 추출할 수 있는 조건, 예를 들어서 90 ~ 100℃ 온도로 10 ~ 20시간 동안 추출하는 것이 바람직하다.In the above production method, the step (2) is a step of obtaining an extract. At this time, it is preferable that the extraction condition is extracted for 10 to 20 hours under a condition capable of sufficiently extracting the active ingredient contained in the herbal material, for example, at 90 to 100 ° C.
상기 제조방법에 있어서, 상기 단계 3)은 분말화하는 단계로서, 분말화는 추출물을 건조하여 분말화하게 되며, 이때의 건조는 동결 건조로서, 그 조건은 -22 ~ -26℃ 온도에서 2 ~ 5일 동안 건조하는 것이 바람직하다.In the above method, the step 3) is a step of pulverizing, and the pulverization is carried out by drying the extract to powder. The lyophilization is carried out at a temperature of -22 to -26 < It is preferable to dry for 5 days.
상기 단계 4) 및 5)는 이온수를 생산하여 혼합하는 단계로서, 우선, 1차로 해양심층수에 +, -의 전극을 건 후, 이온결합 즉 수소와 산소로 분리되고 해양심층수에는 다양한 미네랄이 용해되어 있고 음이온가 양이온으로 분리되어 집적되게 하고, 2차로 이온교환 수지를 통과하여 이온수를 생산하며, 3차로 생산된 이온수를 기 생산된 한방소재 혼합물과 1 : 100 ~ 1000의 비율로 혼합하는 것이 바람직하다. 이는 한방소재를 저분화할 수 있게 구성하므로, 장 내에서도 소화 흡수가 잘 이루어지게 하여 아토피 등에도 유효한 작용을 하게 한다.The above steps 4) and 5) are steps of producing and mixing ionized water. Firstly, + and - electrodes are attached to the deep sea water firstly, and then ionic bond, that is, hydrogen and oxygen is separated, and various minerals are dissolved in the deep ocean water It is preferable to mix the ionized water with the one-way material mixture produced at the ratio of 1: 100-1000. The ionized water is produced by passing the ionized water through the ion exchange resin. This makes it possible to divide the herbal materials so that digestion and absorption can be performed well even in the intestine, and thus, the atopy and the like can be effectively performed.
또한, 본 발명은 상기 본 발명에 따른 제조방법에 따라 제조된 식품 첨가물을 제공한다.The present invention also provides a food additive prepared according to the process of the present invention.
상기 식품 첨가물에 있어서, 상기 제1 소재, 제2 소재, 제3 소재 및 제4 소재의 함량은 각각 전체 혼합물 100 중량부 대비, 30 내지 50 중량부, 10 내지 30 중량부, 5 내지 15 중량부, 및 0.5 내지 5 중량부인 것이 바람직하다.The content of the first material, the second material, the third material and the fourth material in the food additive is 30 to 50 parts by weight, 10 to 30 parts by weight, 5 to 15 parts by weight , And 0.5 to 5 parts by weight.
상기 식품 첨가물에 있어서, 영지버섯, 지황, 당귀, 작약, 석창포, 소합향, 녹용, 생강, 계지 및 아가리쿠스로 구성된 군으로부터 선택된 하나 또는 둘 이상을 포함하는 제5 소재를 더 포함할 수 있다. 이때, 상기 제5 소재의 함량은 전체 혼합물 100 중량부 대비, 0.1 내지 10 중량부인 것이 바람직하다.The food additive may further include a fifth material comprising one or more selected from the group consisting of Ganoderma lucidum, Rhizoma, Angelica keiskei, Peony root, Seokchangpo, Soybean, Deer, Ginger, Seed and Agaricus. At this time, the content of the fifth material is preferably 0.1 to 10 parts by weight relative to 100 parts by weight of the whole mixture.
상기 식품 첨가물에 있어서, 어성초, 삼백초, 인삼, 황기, 감초, 봉밀, 창이자, 용안육, 신국, 곡아, 상엽, 국화, 갈근, 근대, 대황, 차가버섯, 자소엽, 백지, 녹차, 동충하초, 차조기, 사상자, 토사자, 호도인, 합개, 황금, 대황, 대두황권, 백합, 맥문동, 구기자, 상심자 ,흑지마, 육계, 호초, 소회향, 향유, 감초, 진창미, 율무(의이인), 팥(적소두), 복령, 옥미수, 택사 및 동과피로 구성된 군으로부터 선택되는 하나 이상을 포함하는 제6 소재를 더 포함할 수 있다. 이때, 상기 제6 소재의 함량은 전체 혼합물 100 중량부 대비, 0.1 내지 10 중량부인 것이 바람직하다.In the above-mentioned food additives, it is preferable to use a food additive which is selected from the group consisting of Horseshoe, Saururus chinensis, Ginseng, Hwanggi, Licorice, Bongil, (Red, white, red, blue, red, white, red, blue, red, white, red, blue, , And a sixth material including at least one selected from the group consisting of bamboo, jade bean, liquor, and copper and copper. At this time, the content of the sixth material is preferably 0.1 to 10 parts by weight based on 100 parts by weight of the whole mixture.
또한, 본 발명은 상기 본 발명에 따른 식품 첨가물을 포함하는 천연 기능성 식품을 제공한다.The present invention also provides a natural functional food comprising the food additive according to the present invention.
아울러, 본 발명은 상기 본 발명에 따른 식품 첨가물을 유효성분으로 함유하는 아토피를 포함한 염증성 피부질환 개선 또는 완화용 건강식품을 제공한다.In addition, the present invention provides a health food for improving or alleviating inflammatory skin diseases, including atopic diseases, containing the food additive according to the present invention as an active ingredient.
<실시예 1> 식품 첨가물의 제조≪ Example 1 > Preparation of food additives
본 발명자들은 다음과 같은 방법으로 식품첨가물을 제조하였다.The present inventors prepared food additives in the following manner.
상기 재료를 세척 및 건조한 후, 열수 살균소독을 수행하였다(버섯류는 60℃ 이하에서 저온 살균하였고, 한방소재는 105℃ 1시간 이상 살균하였다). 그런 다음, 자연 온도(25 ~ 42℃)에서 락토바실러스 속의 루테리, 플란타럼, 및 비피도박테리움 속의 락티스, 인판티스를 포함한 혼합균주를 접종한 후 24시간 동안 자연 발효시켰다. 그런 다음, 한방소재 및 버섯류를 혼합 후 60 ~ 99℃의 온도에서 8 ~ 72시간 추출 및 농축을 병행하였다. 그런 다음, 상기 추출 농축물을 -22 ~ -26℃의 온도로 2 ~ 5일간 동결건조하여 분말화하였다. 그런 다음, 1차로 해양심층수에 +, -의 전극을 건 후, 이온결합 즉 수소와 산소로 분리되고 해양심층수에는 다양한 미네랄이 용해되어 있고 음이온가 양이온으로 분리되어 집적되게 한 다음, 2차로 이온 교환 수지를 통과하여 이온수를 생산한 후, 3차로 생산된 이온수를 기 생산된 한방소재 혼합물과 1: 100 ~ 1000의 비율로 혼합하고 포장하였다.The material was washed and dried, followed by hydrothermal disinfection (mushrooms were pasteurized at 60 ° C or lower and the herbal material was sterilized at 105 ° C for 1 hour or more). Then, a mixed strain including Lacterium, Lacterium, Pterantorum and Lactobacillus species of Lactobacillus and Lactobacillus sp. Bacterium was inoculated at a natural temperature (25 to 42 ° C), followed by spontaneous fermentation for 24 hours. Then, the herbal materials and the mushrooms were mixed and then extracted and concentrated at a temperature of 60 to 99 ° C for 8 to 72 hours. Then, the extracted concentrate was lyophilized at a temperature of -22 to -26 DEG C for 2 to 5 days to be powdered. Then, firstly, the electrodes of + and - are applied to the deep ocean water, and the ionic bonds, ie, hydrogen and oxygen, are separated. In the deep ocean water, various minerals are dissolved, the anions are separated into cations, To produce ionized water. Then, the ionized water produced in the third order was mixed with the mixture of the herbal materials produced at the ratio of 1: 100-1000 and packed.
<실시예 2> 식품 첨가물을 첨가한 식품의 제조Example 2 Preparation of Food Added with Food Additives
본 발명자들은 다음과 같은 방법으로 식품첨가물을 이용한 음용수를 제조하였다.The present inventors prepared drinking water using food additives in the following manner.
지방산에스터Sucroose
Fatty acid ester
미역, 다시마, 멸치, 보리새우, 명태 등
현미, 백태콩, 조, 수수, 귀리 등의 잡곡Apple, grape, orange, lemon, grape, mango etc. fruit juice
Seaweed, kelp, anchovy, barley shrimp, pollack, etc.
Brown rice, white beans, mackerel, sorghum and oats
여기서, 쌀은 통상의 쌀을 사용할 수 있으나, 바람직하게는 진창미(陳倉米)를 사용하는 것이 좋다. 동의보감에 따르면, 진창미는 밥이나 죽 또는 미음 형태로 쑤어 먹을 수 있고 장과 위를 수렴시키고 또 위의 기를 조화시키는 기능이 있는 것으로 알려졌다.Herein, rice can be used as ordinary rice, but it is preferable to use Jinjiang rice. According to Donguibogam, it can be squeezed in the form of rice, porridge or mise, and it is known to converge on the bowels and harmonize the above.
또한, 상기 정제수는 일반 수돗물이나 정수 등을 사용할 수도 있으나, 바람직하게는 해양 심층수를 이용하는 것이 좋다. 해양 심층수는 그 안에 함유된 4대 필수미네랄을 인체에 함께 공급할 수 있어 인체에서의 알레르기 반응과 가려움 유발을 줄일 수 있기 때문이다.The purified water may be ordinary tap water or purified water, but it is preferable to use deep sea water. Deep sea water can supply the four essential minerals contained in it to the human body, thus reducing allergic reactions and itching in the body.
상기 재료를 세척 및 건조한 후, 열수 살균소독을 수행하였다(버섯류는 60℃ 이하에서 저온 살균하였고, 한방소재는 105℃ 1시간 이상 살균하였다). 그런 다음, 자연 온도(25 ~ 42℃)에서 락토바실러스 속의 루테리, 플란타럼, 및 비피도박테리움 속의 락티스, 인판티스를 포함한 혼합균주를 접종한 후 24시간 동안 자연 발효시켰다. 그런 다음, 한방소재 및 버섯류를 혼합 후 60 ~ 99℃의 온도에서 8 ~ 72시간 추출 및 농축을 병행하였다. 그런 다음, 상기 추출 농축물을 -22 ~ -26℃의 온도로 2 ~ 5일간 동결건조하여 분말화하였다. 그런 다음, 1차로 해양심층수에 +, -의 전극을 건 후, 이온결합 즉 수소와 산소로 분리되고 해양심층수에는 다양한 미네랄이 용해되어 있고 음이온가 양이온으로 분리되어 집적되게 한 다음, 2차로 이온 교환 수지를 통과하여 이온수를 생산한 후, 3차로 생산된 이온수를 기 생산된 한방소재 혼합물과 1: 100 ~ 1000의 비율로 혼합하고 포장하였다.The material was washed and dried, followed by hydrothermal disinfection (mushrooms were pasteurized at 60 ° C or lower and the herbal material was sterilized at 105 ° C for 1 hour or more). Then, a mixed strain including Lacterium, Lacterium, Pterantorum and Lactobacillus species of Lactobacillus and Lactobacillus sp. Bacterium was inoculated at a natural temperature (25 to 42 ° C), followed by spontaneous fermentation for 24 hours. Then, the herbal materials and the mushrooms were mixed and then extracted and concentrated at a temperature of 60 to 99 ° C for 8 to 72 hours. Then, the extracted concentrate was lyophilized at a temperature of -22 to -26 DEG C for 2 to 5 days to be powdered. Then, firstly, the electrodes of + and - are applied to the deep ocean water, and the ionic bonds, ie, hydrogen and oxygen, are separated. In the deep ocean water, various minerals are dissolved, the anions are separated into cations, To produce ionized water. Then, the ionized water produced in the third order was mixed with the mixture of the herbal materials produced at the ratio of 1: 100-1000 and packed.
<실시예 3> 아토피 피부염의 증상 완화 효과 확인<Example 3> Confirmation of symptom relief effect of atopic dermatitis
본 발명자들은 상기 <실시예 2>에서 제조된 음용수를 이용하여 아토피 피부염의 증상 완화 효과를 확인하기 위해, 아토피 피부염을 앓고 있는 11세의 청소년(남)과 63세의 노인(남)을 대상으로 각각 4개월 및 2개월간 하루 한 잔씩 복용(300 ml)한 후, 복용 전후 진행결과를 관찰하였다.In order to confirm the symptom relief effect of atopic dermatitis using the drinking water prepared in the above <Example 2>, the present inventors conducted an examination of an 11-year old adolescent (male) and a 63-year- After taking one cup per day (300 ml) for 4 months and 2 months, the progress was observed before and after the administration.
그 결과, 도 1 및 도 2에 나타난 바와 같이, 아토피 피부염의 증상이 현저히 완화 된 것을 확인하였다(도 1 및 도 2).As a result, it was confirmed that symptoms of atopic dermatitis were remarkably alleviated as shown in Figs. 1 and 2 (Fig. 1 and Fig. 2).
Claims (10)
상기 제1 단계에서 얻어진 발효 처리된 혼합소재를 농축 추출하는 제2 단계;
상기 제2 단계에서 얻어진 농축 추출물을 동결건조하여 분말을 얻는 제3 단계;
상기 제3 단계에서 얻어진 농축 추출물을 나노처리하여 용액을 얻는 제4 단계; 및
상기 제3 단계에서 얻어진 동결건조 분말 및 상기 제4 단계에서 얻어진 나노처리용액을 혼합하는 단계를 포함하는 식품 첨가물의 제조방법.
A first material comprising at least one selected from the group consisting of carnauba, rhizome, and bean curd; A second material comprising at least one member selected from the group consisting of alfalfa, shiitake, and baby leaf; A third material comprising at least one selected from the group consisting of napkins, hornbills, malt, and strangers; And a fourth material containing at least one selected from the group consisting of a pathogen, a hornbeam, and an oak seed;
A second step of concentrating and extracting the fermented mixed material obtained in the first step;
A third step of lyophilizing the concentrated extract obtained in the second step to obtain a powder;
A fourth step of nano-treating the concentrated extract obtained in the third step to obtain a solution; And
And mixing the freeze-dried powder obtained in the third step and the nanoprocessed solution obtained in the fourth step.
상기 제4 단계는 12종 혼합 유산균, 효모 건조물, 당화균(고초균), 라이조(황국균), 김치스티터(MG865), 브루어스 이스트파우터(맥주효모) 및 클로렐라균을 포함하는 혼합균주를 이용하여 이루어지는 것을 특징으로 하는 식품 첨가물의 제조방법.
The method according to claim 1,
The fourth step is a step of using a mixed strain comprising 12 kinds of mixed lactic acid bacteria, yeast dried product, saccharification bacteria (Bacillus subtilis), Rizzo (Hwang Kuk Kyun), Kimchi steer (MG865), Brewers yeast fowl (brewer's yeast) ≪ / RTI >
상기 제4 단계는 체리세이지, 감국, 원추리, 달맞이, 민들레 및 익모초를 포함하는 자연발효액을 첨가하여 이루어지는 것을 특징으로 하는 식품 첨가물의 제조방법.
The method according to claim 1,
Wherein the fourth step comprises adding a natural fermentation broth containing cherry sage, sweet potato, semicircular bean, dalmatia, and motherwort.
제1 소재, 제2 소재, 제3 소재 및 제4 소재의 함량은 각각 전체 혼합물 100 중량부 대비, 30 내지 50 중량부, 10 내지 30 중량부, 5 내지 15 중량부, 및 0.5 내지 5 중량부인 것을 특징으로 하는 식품 첨가물의 제조방법.
The method according to claim 1,
The content of the first material, the second material, the third material and the fourth material is 30 to 50 parts by weight, 10 to 30 parts by weight, 5 to 15 parts by weight, and 0.5 to 5 parts by weight, ≪ / RTI >
제1 단계에서 영지버섯, 지황, 당귀, 작약, 석창포, 소합향, 녹용, 생강, 계지, 및 아가리쿠스 중의 하나 이상을 포함하는 제5 소재를 더 첨가하는 것을 특징으로 하는 식품 첨가물의 제조방법.
The method according to claim 1,
Wherein a fifth material comprising at least one of Ganoderma lucidum, Rhodiola, Angelica keiskei, Peony root, Seokchangpo, Soybean curd, Deer, Ginger, Glue and Agaricus is further added in the first step.
제5 소재의 함량은 전체 혼합물 100 중량부 대비, 0.1 내지 10 중량부인 것을 특징으로 하는 식품 첨가물의 제조방법.
6. The method of claim 5,
Wherein the content of the fifth material is 0.1 to 10 parts by weight based on 100 parts by weight of the total mixture.
제1 단계에서 어성초, 삼백초, 인삼, 황기, 감초, 봉밀, 창이자, 용안육, 신국, 곡아, 상엽, 국화, 갈근, 근대, 대황, 차가버섯, 자소엽, 백지, 녹차, 동충하초, 차조기, 사상자, 토사자, 호도인, 합개, 황금, 대황, 대두황권, 백합, 맥문동, 구기자, 상심자 ,흑지마, 육계, 호초, 소회향, 향유, 감초, 진창미, 율무(의이인), 팥(적소두), 복령, 옥미수, 택사 및 동과피로 구성된 군으로부터 하나 이상을 포함하는 제6 소재를 더 첨가하는 것을 특징으로 하는 식품 첨가물의 제조방법.
The method according to claim 1,
In the first step, it is found that in the first step, there is a tendency that, in the first step, the ginseng root, saury, ginseng, hwanggi, licorice, (Red), red liquor, mulmongdong, gugija, longevity, black bean, broiler, horyu, small scent, ointment, licorice, mulberry, yulmu, red bean Wherein the sixth material is at least one selected from the group consisting of amorphous silicon, amorphous silicon, amorphous silicon, tantalum, and copper and tantalum.
제6 소재의 함량은 전체 혼합물 100 중량부 대비, 0.1 내지 10 중량부인 것을 특징으로 하는 식품 첨가물의 제조방법.
8. The method of claim 7,
Wherein the content of the sixth material is 0.1 to 10 parts by weight relative to 100 parts by weight of the total mixture.
A food additive prepared according to the process of any one of claims 1 to 8.
A natural functional food comprising a food additive prepared according to the process of any one of claims 1 to 8.
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