KR20190037493A - Automatic Smear Apparatus for Liquid Base Cytology - Google Patents

Abstract

The present invention relates to an automatic liquid cell smearing apparatus. The apparatus includes: a test tray part rotated in accordance with a supply position as a container, a pipette, and a filter are stored radially in a line on a plurality of positions; a main grip part placed on a side of left and right lines of the test tray part to be moved to be rotated in every direction, moved in every direction while being gripped on a position, in which the filter in the test tray part is installed, and moved to positions in which the pipette is divided and absorbed by rotation; a pipette operating part placed on a side of the main grip part to be moved along with the main grip part while absorbing and dividing a liquid cell while having the stored pipette attached and detached through pneumatic action; a smearing part placed at the lower part of the main grip part so that the filter moved in the main grip part is inserted into the center, and having the slide supported in the lower part to divide and smear the liquid cell absorbed through the pipette operating part; a slide tray part placed on a side of the smearing part so that the slide before smearing and the slide after smearing are located in divided spaces; and a slide grip part placed on a side of front and rear lines of the smearing part to supply the slide to or collect the same from the smearing part while gripping the slide. Therefore, the present invention is capable of increasing the efficiency of the tests.

Description

Automatic Smear Apparatus for Liquid Base Cytology < RTI ID = 0.0 >

The present invention relates to an automatic liquid cell smearing apparatus, and more particularly, to an automatic liquid cell smearing apparatus which is capable of performing a liquid smear cell slide smear by dispensing a solution container containing a sample and a solution solution, The present invention also relates to an automatic liquid cell smearing apparatus which improves the inspection efficiency as the slide smearing process is automatically and easily performed.

Generally, in order to examine whether or not the body is abnormal, the cells corresponding to the core examination area are collected, the collected cells are stored in a solution container containing the cell solution solution, the cells are attached to the slide, have.

According to this method, after having a separate solution container for dispersing the cells in the solution in the solution, the solution container is shaken to pour the solution into another container while the cells are sufficiently spread in the liquid, When the container is separated from the main body so as to approach the slide, the mixed liquid remaining in the container is poured down by gravity and is lost. do.

However, since the process of transferring the cells from the solution container to the slide must be performed manually by the user, it is time consuming and the contaminants or impurities may be transferred from the user's hand to the slide, There was a problem.

In addition, foreign substances may be contained in cells other than the cells collected in the solution container. In this case, since separation of foreign substances and cells is not easy, separate tools for separation are required.

In the automatic liquid cell smearing apparatus of the prior art, a device for sucking and dispensing the solution at a position where the solution is supplied from a different location, The apparatus is complicated in structure and requires a device to be transported by each position, thereby causing a problem of occupying a large number of devices.

DISCLOSURE Technical Problem The present invention has been conceived to solve the above-mentioned problems, and an object of the present invention is to provide a method and apparatus for supplying a solution container, a filter, and a suction pipette containing a specimen and a solution solution at the same time, The present invention also provides an automatic liquid cell smearing apparatus in which the slide is smoothened automatically after the smear process is performed.

The objects of the present invention are not limited to the above-mentioned objects, and other objects not mentioned can be clearly understood from the following description.

In order to achieve the above object, the automatic liquid cell smashing apparatus according to an embodiment of the present invention comprises a container for containing liquid cells containing a test cell and a solution, which is sucked and divided by a pipette, filtered by a filter, The apparatus comprising: an inspection tray unit which is arranged in a row at a plurality of positions in a radial direction, the inspection tray unit being rotated according to a supply position; The inspection tray unit is disposed on one side on the left and right sides of the inspection tray unit and moves up and down, left and right, and rotates while being gripped to a position where the filter stored in the inspection tray unit is gripped A main grip portion adapted to be moved to a position where the pipette is sucked and dispensed; A pipette operation part disposed at one side of the main grip part and moving together with the main grip part to suck and dispense liquid cells while the pipette housed by the action of air pressure is dismounted and attached; The main body includes a main grip portion and a main grip portion. The main grip portion is disposed at a lower portion of one side of the main grip portion. The filter is movably inserted in the main grip portion. A smear unit supported by the smear; A slide tray unit disposed on one side of the smear unit and configured to receive and slide the slide to be gripped by the smear unit, the slide tray being positioned in the divided space before the smear and the smear after being smoked; And a slider which is disposed on one side of the front and rear of the smear unit and moves back and forth and up and down in a state of gripping the slide received in the slide tray unit so as to be supported by the smear unit by rotation, And a slide grip portion provided to be retracted to the slide tray portion in a gripped state.

The inspection tray portion has a container storage groove in which the container and the filter are housed and housed and in which the container is inserted and housed so as to be housed in a row at a plurality of radial positions, A main tray body having a disc shape having a filter receiving groove in which a filter is housed and having a tray space which is a space in which the pipette is housed in the center; A sub tray body disposed at the center of the main tray body and having a pipette receiving groove into which the pipette is inserted and stored at a plurality of radial positions so as to be in line with the container receiving groove and the filter receiving groove; A rotary plate disposed at the lower portion of the main tray body and the sub tray body and supporting the main tray body and the sub tray body to rotate together; A tray rotating shaft disposed at a lower portion of the rotating plate and provided in a shaft shape to transmit power to be rotated to the rotating plate; And a tray rotating motor disposed below the tray rotating shaft and providing power for rotating the tray rotating shaft.

The main grip portion is disposed on the rear side of the left and right movement lines of the inspection tray portion and moves from the upper portion of the inspection tray portion to the upper portion of the smear portion in the left and right direction according to the conveying position of the container, A left and right feed module provided to feed the left and right feed modules; A left and right conveying body disposed on a front surface of the left and right conveying modules and being provided in a bracket shape fixed to the left and right conveying modules and conveyed to the left and right; A vertical transfer module disposed on a front surface of the left and right transfer bodies and configured to move up and down at a position of the left and right transfer bodies moved left and right by the operation of the left and right transfer modules; A vertical transfer body disposed on a front surface of the upper transfer module and having a pipette operation part which is fixed to the upper transfer module and is vertically conveyed in a bracket shape and which is vertically and horizontally moved together; A rotatable supporter disposed at the center of the front surface of the upper body and supporting the supporter rotatably in a horizontal direction at a lower portion thereof; A rotary motor disposed on the upper portion of the rotary support and providing power to be rotated horizontally at a lower portion thereof; A rotary shaft projecting from a lower portion of the rotary motor and transmitting rotational force to the lower portion through the rotary support body; A main gripper driving body supported at a lower portion of the rotation shaft and rotated by operation of the rotation motor while providing a gripping force for adjusting the distance from the center to both sides; And a plurality of grippers disposed at a lower portion of the main gripper drive body for gripping the cylindrical container and the filter at radial positions and being spaced apart from each other by the operation of the main gripper drive body while being horizontally, And a main gripper for performing a grip operation while being adjusted.

The pipette actuating part is disposed on one side of the main grip part and supports the main grip part in a fixed state so as to be moved left and right and up and down together with the main grip part. A pipette support ring which is movably supported by the pipette support body so as to be movable up and down and which is hollow in shape so as to apply air pressure to the inside of the pipette support while moving together with the main grip portion, A pipette insertion body for sucking the liquid cells of the container while dispensing by the insertion of the pipette placed at the injection port and dispensing the liquid cells at the injection port position; A pipette uprising module disposed at one side of the main grip part and fixed to the pipette insert at one side of the pipette support body to move up and down the pipette support module; A pneumatic connection tube connected to an upper portion of the pipette insert to connect the pipette insert to supply air pressure for sucking and discharging the pipette insert; A pneumatic cylinder disposed at one side of the main grip portion and connected to the pneumatic connection tube to generate an air pressure sucked or discharged; A pneumatic piston disposed inside the pneumatic cylinder and reciprocating to adjust a pressure to be sucked or discharged according to a moving direction while moving in the pneumatic cylinder; A piston transfer block disposed at one side of the pneumatic piston and connected to the pneumatic piston and transferred together therewith; And a piston motor fixed to the piston transfer block and providing a reciprocating power of the pneumatic piston to move the piston transfer block.

The smear unit may include a smear body disposed at a lower side of the main grip unit and having a filter insertion hole positioned at one side of the inspection tray unit and inserted into the center of the filter unit, the filter being inserted into the main grip unit; A fastening protrusion disposed inside the smear body and protruding in a spiral direction from the inner wall of the filter insertion hole toward the center and fastened and disassembled by rotation of the filter; And a smear support disposed at a lower portion of the smear body and supporting the slides to be transported by the slide grip portion to a lower portion of the filter insertion hole to smear liquid cells having passed through the filter .

In addition, the slide tray portion is disposed on the front surface of the smearing portion, and has an interior space having an upper portion opened to house the slide, and a partitioning partition wall dividing the space into the center of the interior space A slide tray body on which one of the slides is installed before the smearing and the slide is placed on the other side after smearing; And a slide housing body disposed inside the slide tray body and having slide insertion grooves at a plurality of positions so that both ends of the slide are positioned and positioned on opposite sides of the housing space, have.

The slide grip section is disposed forward of the back and forth movement line of the smear section and is configured to move in the forward and backward directions from the position where the slide is stored to the slide position of the smear section. A slide conveying body disposed on the right side of the forward / backward conveying module, the slide conveying body being fixed to the forward / backward conveying module and being provided in the form of a bracket for forward / backward conveyance; A vertical transfer means disposed on a right side of the slide transfer body and adapted to transfer the transfer material from the right side of the slide transfer body up and down; A vertical conveying unit disposed on a right side of the upper conveying unit and having a bracket shape fixed to the upper conveying unit and vertically conveyed; A gripper rotating motor which is disposed on a right side of the upper sheet conveying body and which is fixed to the upper sheet conveying body and provides a rotating force to be vertically rotated while being fed together; A gripper support disposed on a right side surface of the gripper rotation motor and having a bracket shape fixed to the gripper rotation motor and rotated in a vertical direction; A gripper actuating body which is disposed on one side of the gripper support body and is fixed to the gripper support body so as to be moved back and forth, up and down, and rotated, and which provides a grip force adjusting the gap from the center to both sides; And a pair of grippers operatively disposed on opposite sides of the gripper operating body, gripping the slide while controlling the gap by the operation of the gripper operating body, and transferring the slide to the smearing unit, And a slide gripper for recovering the slide.

BRIEF DESCRIPTION OF THE DRAWINGS The above and other objects, features and advantages of the present invention will be more apparent from the following detailed description taken in conjunction with the accompanying drawings, in which: FIG.

It should be understood, however, that the invention is not limited to the disclosed embodiments, but may be embodied in many different forms and should not be construed as being limited to the embodiments set forth herein, It is provided to fully inform the owner of the scope of the invention.

According to one of the above-mentioned objects of the present invention, an automatic liquid cell smashing apparatus according to an embodiment of the present invention is characterized in that, when performing slide smear of a liquid sample, a solution container containing a sample and a solution solution, And the slide is smoothed after the smear is supplied and the slide smearing process is automatically and easily performed. Thus, the inspection efficiency is improved.

Also, the automatic liquid cell smashing apparatus according to the embodiment of the present invention is a system in which a plurality of filters, a container, and a pipette are simultaneously supplied to a side surface of a smear unit, The present invention provides an effect of improving the inspection efficiency by simplifying the process of sucking and dispensing liquid cells according to the storage box by dividing the pre-sack and post-sack, and transferring the slides to the process of sacking.

1 is a perspective view showing an automatic liquid cell smearing apparatus according to an embodiment of the present invention.
2 is a partially cutaway perspective view showing the automatic liquid cell smearing apparatus of FIG.
3 is a plan view showing an inspection tray unit which is a main part of the automatic liquid cell smashing apparatus of FIG.
FIG. 4 is a front view showing a test tray unit which is a main part of the automatic liquid cell smearing apparatus of FIG. 1; FIG.
5 is a front view showing a main grip part and a pipette operation part which are main parts of the automatic liquid cell smashing device of FIG.
FIG. 6 is a perspective view of the main grip portion and the pipette operating portion, which are essential portions of the automatic liquid cell smearing apparatus of FIG.
FIG. 7 is a state diagram showing a state in which the filter is gripped and moved to the upper part of the smear unit in the automatic liquid cell smearing apparatus of FIG. 1;
FIG. 8 is a state diagram showing a state in which the pipette operation portion of the automatic liquid cell smashing apparatus of FIG. 1 is operated in stages.
FIG. 9 is a configuration diagram showing a part of the pipette operation unit which is a main part of the automatic liquid cell smashing apparatus of FIG. 1;
Fig. 10 is a use state diagram showing a state in which a filter of the automatic liquid cell smearing apparatus of Fig. 1 is installed in the smear unit; Fig.
FIG. 11 is a perspective view showing a slide tray portion and a slide grip portion, which are essential portions of the automatic liquid cell smearing apparatus of FIG.
FIG. 12 is a state diagram showing a state in which the slide of the automatic liquid cell smashing apparatus of FIG. 11 is rotated and mounted on the smear unit;

While the invention is susceptible to various modifications and alternative forms, specific embodiments thereof are shown by way of example in the drawings and will herein be described in detail. It should be understood, however, that the invention is not intended to be limited to the particular embodiments, but includes all modifications, equivalents, and alternatives falling within the spirit and scope of the invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings. In addition, numerals (e.g., first, second, etc.) used in the description of the present invention are merely an identifier for distinguishing one component from another.

Also, in this specification, when an element is referred to as being "connected" or "connected" with another element, the element may be directly connected or directly connected to the other element, It should be understood that, unless an opposite description is present, it may be connected or connected via another element in the middle.

The suffix "module" and " part "for the components used in the following description are given or mixed in consideration of ease of specification, and do not have their own meaning or role. Further, in order to clearly explain the present invention, parts not related to the description are omitted in the drawings, and the width, length, thickness, etc. of the components may be exaggerated for convenience. Like reference numerals refer to like elements throughout the specification.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

FIG. 1 is a perspective view showing an automatic liquid cell smearing apparatus according to an embodiment of the present invention, FIG. 2 is a partially cutaway perspective view showing the automatic liquid cell smashing apparatus of FIG. 1, FIG. 4 is a front view showing an inspection tray unit which is a main part of the automatic liquid cell smearing apparatus of FIG. 1, and FIG. 5 is a plan view showing a main portion of the automatic liquid cell- And FIG. 6 is a perspective view showing the operation state of the main grip portion and the pipette operating portion which are the main portions of the automatic liquid cell smashing apparatus of FIG. 1, and FIG. 7 is a cross- FIG. 8 is a view showing the state of use of the automatic liquid cell smearing apparatus of FIG. 1, FIG. 9 is a configuration diagram showing a part of the pipette operation part which is a main part of the automatic liquid cell smashing apparatus of FIG. 1, and FIG. 10 is a schematic view showing a part of the automatic liquid cell smearing apparatus of FIG. FIG. 11 is a perspective view showing a slide tray portion and a slide grip portion, which are the main parts of the automatic liquid cell smashing apparatus of FIG. 1, and FIG. And the slide of the cell smearing apparatus is rotated and mounted on the smear unit.

1 to 12, an automatic liquid cell smashing apparatus 100 according to an embodiment of the present invention includes a pipette 30 in a container 10 containing liquid cells containing a test cell and a solution solution, Filtered and filtered by the filter 20, and then applied to the slide 40.

The automated liquid cell smearing apparatus 100 includes an inspection tray unit 110 in which the container 10, the pipette 30 and the filter 20 are accommodated, a main grip unit 120, a pipette operation unit 130, A slide tray unit 150, and a slide grip unit 160. The slide tray unit 150 includes:

The inspection tray unit 110 includes a container 10, a pipette 30, and a filter 20 housed in a row at a plurality of positions in a radial direction, and is rotatable according to a supply position.

The inspection tray unit 110 includes a main tray body 111, a sub tray body 115, a rotation plate 117, a tray rotation shaft 118, and a tray 110 on which the container 10 and the filter 20 are accommodated. And a rotation motor 119.

The main tray body 111 is arranged so that the container 10 and the filter 20 are accommodated and housed and the container 10 is placed so that the container 10 and the filter 20 are housed in a row at a plurality of positions in a radial direction (114) which is a space in which a pipette (30) is accommodated in the center and has a disc shape having a filter storage groove (113) in which a filter (20) do.

That is, the main tray body 111 has a radial position in which the container 10 and the filter 20 are housed in a radial direction aligned in the center by rotation in consideration of the transfer position of the main grip portion 120, The container holding groove 112 and the filter receiving groove 113 are formed in the shape of a circular plate so that the container 10 and the filter 20 are inserted and positioned.

The sub tray body 115 is disposed at the center of the main tray body 111 and the pipette 30 is inserted and stored at a plurality of radial positions so as to be aligned with the container receiving groove 112 and the filter receiving groove 113 And has a pipette receiving groove 116. That is, the pipetting body 115 is provided with the filter 20 and the pipette 30 independently from the vessel 10 at a position apart from the vessel 10 as the pipette 30 is pressed to be inserted and removed by the operation of the pipette operation part 130. [ The pipette receiving grooves 116 are formed at a plurality of radial positions so as to be disposed in the same column as the plurality of vessels 10 and the filter 20 positioned in the insertion direction.

The rotation plate 117 is disposed below the main tray body 111 and the sub tray body 115 and supports the main tray body 111 and the sub tray body 115 so as to rotate together.

The tray rotating shaft 118 is disposed at a lower portion of the rotating plate 117 and is provided in a shaft shape to transmit the rotating power to the rotating plate 117.

The tray rotating motor 119 is disposed below the tray rotating shaft 118 and is provided to provide power for rotating the tray rotating shaft 118. Here, when the container 10, the filter 20, and the pipette 30 are transported for smearing by setting the rotation angle of the tray rotation motor 119 to an angle aligned with one of the plurality of radial columns, And a stepping motor that rotates stepwise to rotate the vessel 10, the filter 20, and the pipette 30 in a row.

The main grip part 120 is disposed on one side of the left and right sides of the inspection tray part 110. The main grip part 120 moves to the right, left, up and down, and rotates to a position where the filter 20 stored in the inspection tray part 110 is installed, And is driven to be installed by rotation, and is moved to a position where the pipette 30 is sucked and a position where it is dispensed.

The main grip portion 120 includes a left and right feed module 121, a left and right feed body 122, an upper feed module 123, a vertical feed module 122, A rotary support 125, a rotary motor 126, a rotary shaft 127, a main gripper drive unit 128, and a main gripper 129. The main gripper 129,

The left and right conveying modules 121 are disposed on the left rear side of the main tray body 111 and extend from the upper portion of the main tray body 111 to the upper portion of the smear portion 140, And the transfer position of the pipette 30 in the left and right directions.

The left and right conveying body 122 is disposed on the front surface of the left and right conveying module 121 and is provided in the form of a bracket fixed to the left and right conveying module 121 and conveyed to the left and right.

The upper and lower transfer modules 123 are disposed on the front surface of the left and right transfer bodies 122 and are provided to move up and down at the positions of the left and right transfer bodies 122 moved left and right by the operation of the left and right transfer module 121 .

The upper and lower shipment bodies 124 are disposed on the front surface of the upper and lower feeding modules 123 and are fixed to the upper and lower feeding modules 123 and are provided in the form of brackets to be vertically conveyed. (130).

The rotary support 125 is disposed at the center of the front surface of the upper transfer body 124 and is adapted to support the rotation of the lower portion in the horizontal direction.

The rotary motor 126 is disposed on the upper portion of the rotary support 125 and is installed to provide power to rotate horizontally in the lower portion.

The rotary shaft 127 protrudes from the lower portion of the rotary motor 126 and is configured to transmit the rotational force to the lower portion through the rotary support 125.

The main gripper driving body 128 is supported at a lower portion of the rotating shaft 127 and is provided to be rotated by the operation of the rotating motor 126 while providing a gripping force for adjusting the distance from the center to both sides.

The main gripper 129 is disposed at a lower portion of the main gripper driving body 128 and includes a plurality of main gripper driving bodies 128 for gripping cylindrical vessels and filters at radial positions, So as to perform the grip operation.

The filter 20 placed on the main tray body 111 is lowered by the operation of the vertical transfer module 123 when the filter 20 is positioned on the main tray body 111 by the operation of the left and right feed module 121, The main gripper 129 grips the upper portion of the filter 20. After the filter 20 is gripped, the upper transfer module 123 is operated to lift the upper part, and then the upper transfer module 123 is transferred to the upper part of the smear part 140 by the operation of the left and right transfer module 121, And the filter 20 is installed on the smear part 140 while descending and rotating by the operation of the motor 126.

Here, the pipette operation part 130 may include a position where the pipette 30 housed in the sub tray body 115 is inserted and supported, a position where the liquid cell is sucked in the container 10, a filter installed in the smear part 140, The left and right feed module 121 and the up and down feed module 123 move left and right and upward and downward to move the liquid cell to the position where the liquid cell is dispensed to the pipette 20 and to the position where the pipette 30 inserted after dispensing the liquid cell is removed And is fixed to one side of the upper transfer body 124.

The pipette actuating part 130 is disposed on one side of the main grip part 120. The pipette 30 accommodated by the action of the air pressure while being moved together with the main grip part 120 is detached and attached to suck and dispense liquid cells .

The pipette actuating part 130 includes a pipette support 131, a pipette insert 132, a pipette up and down transfer module 134, a pneumatic connection tube 135 A pneumatic cylinder 136, a pneumatic piston 137, a piston transfer block 138, and a piston motor 139. As shown in FIG.

The pipette support body 131 is disposed at one side of the upper and lower transfer bodies 124 and is fixedly supported to be moved left and right and upward and downward together with the upper and lower transfer bodies 124.

The pipette insert 132 is supported on the pipette support 131 so as to be movable up and down together with the upper and lower transfer bodies 124. The pipette insert 132 is provided in a hollow shape so that air pressure is applied to the pipette insert 132, A pipette support ring 133 is inserted and supported so as to be detachable by insertion of the pipette 30 placed on the sub tray body 115 and sucks the liquid cells of the vessel 10 to be supplied to the smear unit 140, Position.

The pipette up and down transfer module 134 is disposed on one side of the upper transfer body 124 and is fixed to one side of the pipette support 131 and installed to move up and down the pipette insertion body 132.

8, the pipette insert 132 shown in FIG. 8A is moved upward and downward by the operation of the left and right feed module 121 and the vertical feed module 123, And moves to the upper portion of the pipette 30 housed in the sub-tray body 115 in a state of being supported by the sub-tray body 115. The pipette insertion body 132 moves to the upper portion of the pipette 30 and then the pipette 30 is lowered by the operation of the pipette lifting module 134 while the pipette 30 is inserted and supported, As shown in FIG. When the pipetting insert 132 in which the pipette 30 is inserted into the upper part of the vessel 10 is positioned by the operation of the left and right feed module 121 and the vertical feed module 123, The pipette 30 is lowered and transferred to the suction position. After the liquid cells are sucked, they are transferred to the position of the smear unit 140 where the filter 20 is provided, and are dispensed into liquid cells. After the dispensing of the liquid cells is completed, the pipette 30 is transported to a position where the pipette 30 is removed in a reverse order to the operation sequence of the pipette operating part 132 shown in the figure, and then discharged and discharged to the outside by air pressure.

The pneumatic connection tube 135 is connected to the upper portion of the pipette insert 132 and connects to supply the air pressure to suck and discharge the pipette insert 132.

The pneumatic cylinder 136 is disposed at one side of the upper transfer body 124 and is connected to the pneumatic connection tube 135 to generate air pressure to suck or discharge the air.

The pneumatic piston 137 is disposed inside the pneumatic cylinder 136 and is provided to adjust the reciprocating motion of the pressure sucked or discharged according to the moving direction while moving in the pneumatic cylinder 136. [

The piston transfer block 138 is disposed at one side of the pneumatic piston 137 and is connected to the pneumatic piston 137 to be transferred together.

The piston motor 139 is fixed to the piston transfer block 138 and is provided to move the piston transfer block 138 by providing reciprocating power of the pneumatic piston 137.

The pneumatic cylinder 136 connected to the pipette insertion body 132 and the pneumatic connection tube 135 provides a pressure to be sucked or discharged by the operation of the pneumatic piston 137, And a pneumatic piston 137 supported by the piston transfer block 138 by the operation of the piston motor 139 to adjust the strength of the air pressure for ejecting the pipette 30 inserted into the pipette insert 132 ) To adjust the moving distance.

The smear end portion 140 is disposed at a lower portion of one side of the main gripper 129. The filter 20 is gripped by the main gripper 129 at the center and inserted therein. And the slide 40 is supported so as to perform a smear operation.

The smear unit 140 includes an smear body 141, a fastening protrusion 143, and an smear support 144 on which the liquid cells are dispensed on the left side of the main tray body 111 for smearing.

The smear body 141 is disposed at a lower portion of one side of the main gripper 129. The smear body 141 is positioned at the left side of the main tray body 111 and is inserted into the main gripper 129, And has a filter insertion hole 142.

The fastening protrusion 143 is disposed inside the smear body 141 and protrudes spirally from the inner wall of the filter insertion hole 142 toward the center so as to be fastened and disassembled by rotation of the filter 20.

The smear support 144 is disposed at a lower portion of the smear body 141. The slides 40 to be gripped by the slide grip portions 160 are positioned below the filter insertion holes 142, So that the liquid-phase cells are smudged.

The slide tray unit 150 is disposed on the front surface of the smear support member 144 and is configured to receive and slide the slide 40 to be gripped by the smear support member 144, 40 in the divided spaces.

The slide tray unit 150 includes a slide tray body 151 in which the slide 40 is housed and housed, and a slide housing 154.

The slide tray body 151 is disposed on the front surface of the smear support body 144. The slide tray body 151 has an interior space 152 which is open with its top opened to receive the slide 40, A partition wall 153 dividing a space into a central portion of the partition wall 153 is provided and divided so that the slide 40 is placed on the one side and the slide 40 is placed on the other side.

The slide inner body 154 is disposed inside the slide tray body 151 and is disposed on each of opposite sides of the inner space 152 so as to be slid in a plurality of positions so that both ends of the slide 40 are inserted, And has an insertion groove 155. The slide inner body 154 is inserted and supported in the slide insertion groove 155 so as to maintain a gap at which the plurality of slides 40 in the form of a glass can be gripped by the slide grip portion 160, So that the efficiency of storage can be improved.

The slide grip portion 160 is disposed on one side of the front and rear of the smear portion 140. The slide grip portion 160 is moved up and down in the state of gripping the received slide 40 and is supplied to be supported by the smear portion 140 by rotation , And when the slide is completed, the slide 40 is retracted to a position where it is held in a gripped state.

The slide grip portion 160 includes a front and rear conveyance module 161 for conveying the slide 40 forward and backward, a slide conveyance body 162, an upper and lower conveyance means 163, a vertical conveyance support member 164, a gripper rotation motor 165, A support 166, a gripper actuating member 167, and a slide gripper 168.

The back and forth conveying module 161 is disposed in front of the back and forth moving lines of the smear support body 144 so as to move in the forward and backward directions from the position where the slide 40 is housed to the slide seat position of the smear support body 144 Respectively.

The slide conveying body 162 is disposed on the right side of the forward / backward conveying module 161 and is provided in a bracket shape fixed to the forward / backward conveying module 161 and conveyed back and forth.

The upper and lower feeding means 163 are disposed on the right side of the slide conveying body 162 and are provided so as to be vertically conveyed from the right side of the slide conveying body 162.

The upper conveying unit 164 is disposed on the right side of the upper conveying unit 163 and is provided in the form of a bracket fixed to the upper conveying unit 163 and vertically conveyed.

The gripper rotating motor 165 is disposed on the right side of the upper conveyance support body 164 and is installed to provide a rotational force which is fixed to the upper conveyance support body 164 and is vertically rotated while being fed together.

The gripper support body 166 is disposed on the right side of the gripper rotation motor 165 and is provided in the form of a bracket fixed to the gripper rotation motor 165 and rotated in the vertical direction.

The gripper actuating member 167 is disposed on one side of the gripper support 166 and is fixed to the gripper support 166 for forward, backward, up and down, and to be rotated, and is provided to provide a gripping force to adjust the distance from the center to both sides.

The slide gripper 168 is disposed on one side of the gripper operating body 167 and is provided as a pair facing each other. The slide gripper 168 grips the slide 40 while adjusting the gap by the operation of the gripper operating body 167, 144, and is provided to recover the smear slide 40 from the smear support 144.

It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the essential characteristics thereof.

Therefore, the embodiments disclosed in the present invention are intended to illustrate rather than limit the scope of the present invention, and the scope of the technical idea of the present invention is not limited by these embodiments.

The scope of protection of the present invention should be construed according to the following claims, and all technical ideas within the scope of equivalents should be construed as falling within the scope of the present invention.

Description of the Related Art
100: smearing apparatus 110: inspection tray unit
111: main tray body 112: container storage groove
113: filter storage groove 114: tray space
115: sub tray body 116: pipette storage groove
117: rotation plate 118: tray rotation axis
119: tray rotation motor 120: main grip part
121: right and left feed module 122: left and right feed body
123: Shanghai Song module 124: Shanghai Song body
125: rotary support 126: rotary motor
127: rotational shaft 128: main gripper drive body
129: main gripper 130: pipette operation part
131: pipette holder 132: pipette holder
133: pipette support ring 134: pipette up and down transfer module
135: Pneumatic connecting tube 136: Pneumatic cylinder
137: Pneumatic piston 138: Piston transfer block
139: Piston motor 140:
141: smear body 142: filter insertion hole
143: fastening protrusion 144: smear support
150: slide tray part 151: slide tray body
152: Ante space 153: Split bulkhead
154: slide inner body 155: slide insertion groove
160: slide grip part 161: forward / backward feed module
162: slide conveying body 163: upper and lower conveying means
164: Shanghai conveyance delay 165: Gripper rotation motor
166: gripper support body 167: gripper operation body
168: Slide gripper

Claims (7)

An automatic liquid cell smearing apparatus in which a liquid containing a test cell and a solution liquid is sucked and divided by a pipette into a container, filtered with a filter, and then applied to a slide,
An inspection tray portion which is arranged in a row at a plurality of positions in a radial direction of the container, the pipette, and the filter, and is rotated according to a supply position;
The inspection tray unit is disposed on one side on the left and right sides of the inspection tray unit and moves up and down, left and right, and rotates while being gripped to a position where the filter stored in the inspection tray unit is gripped A main grip portion adapted to be moved to a position where the pipette is sucked and dispensed;
A pipette operation part disposed at one side of the main grip part and moving together with the main grip part to suck and dispense liquid cells while the pipette housed by the action of air pressure is dismounted and attached;
The main body includes a main grip portion and a main grip portion. The main grip portion is disposed at a lower portion of one side of the main grip portion. The filter is movably inserted in the main grip portion. A smear unit supported by the smear;
A slide tray unit disposed on one side of the smear unit and configured to receive and slide the slide to be gripped by the smear unit, the slide tray being positioned in the divided space before the smear and the smear after being smoked; And
The slide is stored in the slide tray unit so that the slide is moved up and down in a state where the slide is gripped and supplied so as to be supported by the smear unit by rotation, And a slide grip part installed to be returned to the slide tray part in a state
Automatic liquid cell smearing device.
The method according to claim 1,
The inspection tray unit
A container storage groove in which the container and the filter are accommodated and housed and in which the container is inserted and housed so that the container and the filter are housed in a row at a plurality of positions in a radial direction, And a tray space which is a space in which the pipette is housed in a center thereof;
A sub tray body disposed at the center of the main tray body and having a pipette receiving groove into which the pipette is inserted and stored at a plurality of radial positions so as to be in line with the container receiving groove and the filter receiving groove;
A rotary plate disposed at the lower portion of the main tray body and the sub tray body and supporting the main tray body and the sub tray body to rotate together;
A tray rotating shaft disposed at a lower portion of the rotating plate and provided in a shaft shape to transmit power to be rotated to the rotating plate; And
And a tray rotating motor disposed below the tray rotating shaft to provide power for rotating the tray rotating shaft
Automatic liquid cell smearing device.
The method according to claim 1,
The main grip portion includes:
A left and right transporting module disposed on a left rear side of the inspection tray section and adapted to move leftward and rightward according to a transport position of the container, the filter, and the pipette from an upper portion of the inspection tray section to an upper portion of the smear section, ;
A left and right conveying body disposed on a front surface of the left and right conveying modules and being provided in a bracket shape fixed to the left and right conveying modules and conveyed to the left and right;
A vertical transfer module disposed on a front surface of the left and right transfer bodies and configured to move up and down at a position of the left and right transfer bodies moved left and right by the operation of the left and right transfer modules;
A vertical transfer body disposed on a front surface of the upper transfer module and having a pipette operation part which is fixed to the upper transfer module and is vertically conveyed in a bracket shape and which is vertically and horizontally moved together;
A rotatable supporter disposed at the center of the front surface of the upper body and supporting the supporter rotatably in a horizontal direction at a lower portion thereof;
A rotary motor disposed on the upper portion of the rotary support and providing power to be rotated horizontally at a lower portion thereof;
A rotary shaft projecting from a lower portion of the rotary motor and transmitting rotational force to the lower portion through the rotary support body;
A main gripper driving body supported at a lower portion of the rotation shaft and rotated by operation of the rotation motor while providing a gripping force for adjusting the distance from the center to both sides; And
A main gripper driving body disposed below the main gripper driving body and having a plurality of cylinders in a radial position for gripping the cylindrical filter and the filter, And a main gripper for performing a grip operation
Automatic liquid cell smearing device.
The method according to claim 1,
Wherein the pipette operation part comprises:
A pipette support disposed at one side of the main grip portion and supporting the main grip portion in a fixed state so as to be moved left and right and up and down together with the main grip portion;
A pipette support ring which is movably supported by the pipette support body so as to be movable up and down and which is hollow in shape so as to apply air pressure to the inside of the pipette support while moving together with the main grip portion, A pipette insertion body for sucking the liquid cells of the container while dispensing by the insertion of the pipette placed at the injection port and dispensing the liquid cells at the injection port position;
A pipette up / down module disposed at one side of the main grip part and fixed to one side of the pipette support body to move the pipette insert up and down;
A pneumatic connection tube connected to an upper portion of the pipette insert to connect the pipette insert to supply air pressure for sucking and discharging the pipette insert;
A pneumatic cylinder disposed at one side of the main grip portion and connected to the pneumatic connection tube to generate an air pressure sucked or discharged;
A pneumatic piston disposed inside the pneumatic cylinder and reciprocating to adjust a pressure to be sucked or discharged according to a moving direction while moving in the pneumatic cylinder;
A piston transfer block disposed at one side of the pneumatic piston and connected to the pneumatic piston and transferred together therewith; And
And a piston motor fixedly mounted on the piston transfer block and providing a reciprocating power of the pneumatic piston to move the piston transfer block
Automatic liquid cell smearing device.
The method according to claim 1,
In the smearing section,
A smear body disposed at a lower side of the main grip portion and having a filter insertion hole located at one side of the inspection tray portion and inserted into the center of the main grip portion to receive the filter;
A fastening protrusion disposed inside the smear body and protruding in a spiral direction from the inner wall of the filter insertion hole toward the center and fastened and disassembled by rotation of the filter; And
And a smear support disposed at a lower portion of the smear body and supporting the slides to be transported by the slide grip portion to a lower portion of the filter insertion hole to smear liquid cells having passed through the filter,
Automatic liquid cell smearing device.
The method according to claim 1,
The slide tray unit includes:
A partition wall which divides a space at the center of the cushioning space is provided, and one side of the cushion is divided into two parts, A slide tray body on which the slide is placed and the slide is placed on the other side; And
And a slide housing body disposed inside the slide tray body and having slide insertion grooves at a plurality of positions so that both ends of the slide are respectively inserted and positioned on opposite sides of the seat space,
Automatic liquid cell smearing device.
The method according to claim 1,
The slide-
A front and rear conveying module disposed in front of a back and forth movement line of the smear section and configured to move in a forward and backward direction from a position where the slide is housed to the slide seat position of the smear section;
A slide conveying body disposed on the right side of the forward / backward conveying module, the slide conveying body being fixed to the forward / backward conveying module and being provided in the form of a bracket for forward / backward conveyance;
A vertical transfer means disposed on a right side of the slide transfer body and adapted to transfer the transfer material from the right side of the slide transfer body up and down;
A vertical conveying unit disposed on a right side of the upper conveying unit and having a bracket shape fixed to the upper conveying unit and vertically conveyed;
A gripper rotating motor which is disposed on a right side of the upper sheet conveying body and which is fixed to the upper sheet conveying body and provides a rotating force to be vertically rotated while being fed together;
A gripper support disposed on a right side surface of the gripper rotation motor and having a bracket shape fixed to the gripper rotation motor and rotated in a vertical direction;
A gripper actuating body which is disposed on one side of the gripper support body and is fixed to the gripper support body so as to be moved back and forth, up and down, and rotated, and which provides a grip force adjusting the gap from the center to both sides; And
The gripper operating body is provided with a pair of facing each other and grips the slide while the gap is adjusted by the operation of the gripper operating body to transfer the grip to the smearing part, And a slide gripper
Automatic liquid cell smearing device.

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