KR102027970B1 - Automatic Smear Apparatus for Liquid Base Cytology - Google Patents

Abstract

The present invention relates to an automatic liquid cell smearing device, comprising: an inspection tray unit accommodating a container, a pipette, and a filter in a plurality of positions on a radial basis and rotating in accordance with a supply position; The pipette is moved up, down, left and right while being disposed to one side on the left and right lines of the inspection tray part and moved to the left, right, up and down, and rotated while being gripped to the position where the filter housed in the inspection tray is installed. A main grip part provided to be moved to a suction position and a dispensing position; A pipette operating part disposed on one side of the main grip part to move and move together with the main grip part to inhale and dispense the liquid cells while the pipette received and detached by the action of air pressure is removed; It is disposed on the lower side of one side of the main grip portion is provided to insert the filter moved in the main grip portion in the center, the slide is supported on the lower portion to dispense the liquid cells sucked from the pipette operation unit to perform smear work Smeared portion; A slide tray part disposed at one side of the smear part and provided to position the slide before smearing and the slide after smearing respectively in a divided space; And a slide grip part disposed on one side of the front and rear lines of the smear part and installed to supply and retrieve the slide part in a state in which the slide is gripped.

Description

Automatic Smear Apparatus for Liquid Base Cytology

The present invention relates to an automatic liquid cell smearing device, and more particularly, when performing a liquid smearing of a liquid sample, a solution container containing a sample and a solution solution, a filter, and a suction pipette are simultaneously supplied and moved to a smeared position. The present invention relates to an automatic liquid cell smearing device for improving inspection efficiency as the slide smearing process is easily and automatically performed after the smearing is performed after feeding the slide in a gripped state.

In general, to check for abnormalities in the body, cells corresponding to the body examination site are collected, the collected cells are preserved in a solution container containing the cell solution solution, and the cells are attached to the slide and then examined under a microscope. have.

According to this method, after having a separate solution container for dispersing the cells in the solution liquid to the liquid, shake the solution container and pour the liquid into another container while the cells are sufficiently spread in the liquid and the suction device under the filter The fluid is sucked in contact with the filter, and the cells filtered by the filter are rubbed onto the slide. The cells and the body are separated to access the slide from the filtered membrane, and the mixed liquid left in the container is poured down by gravity to be lost. do.

However, the process of transferring the cells from the solution container to the slide is time-consuming because it must be done manually by the user, and contaminants or impurities can be transferred from the user's hand to the slide, thereby reducing the accuracy of the cell test. There was a problem.

In addition, foreign matter may be contained in addition to the cells collected in the solution container, in which case it is not easy to separate the foreign matter and cells, a separate tool for separation was required.

The automatic liquid cell smearing device of the prior art is provided with a device for feeding and dispensing the container and the filter containing the solution liquid and the cells at different locations to inhale and dispense at the location where the container is supplied, in order to smear the slide. As the device is supplied from the supplied position to the smeared position, the structure is complicated, and the device to be transported by each position takes a lot of devices.

The present invention has been made to solve the above problems, an object of the present invention is to move to a smeared position by simultaneously supplying a solution container, a filter, and a suction pipette containing a sample and a solution solution when performing a slide smear of a liquid sample While dispensing, feeding the slide in a gripped state and then recovering after smearing, the slide smearing process is easily and automatically performed, thereby providing an automatic liquid cell smearing device that improves test efficiency.

The objects of the present invention are not limited to the above-mentioned objects, and other objects that are not mentioned will be clearly understood from the following description.

In order to achieve the above object, the automatic liquid cell smearing device according to an embodiment of the present invention is aspirated by a pipette in a container containing a liquid cell containing a test cell and a solution solution, filtered by a filter and smeared on a slide An automatic liquid cell smear apparatus, comprising: an inspection tray part accommodating the container, the pipette and the filter in a plurality of positions in a radial position, and rotating according to a supply position; It is disposed on one side on the left and right lines of the inspection tray portion, and moved to the left and right, up and down, and rotated so as to be installed by rotating by moving up, down, left and right in a state where the filter accommodated in the inspection tray is installed. A main grip part driven to move to a position where the pipette is sucked and a dispensed position; A pipette operation part disposed on one side of the main grip part and configured to suck and dispense liquid cells while the pipette is detached and detached by the action of air pressure while being moved together with the main grip part; The slide is disposed at one lower side of the main grip part, and the filter is inserted into and mounted at the center of the main grip part, and the slide is disposed at the lower part so as to dispense the liquid cells sucked from the pipette operation part to perform smearing. Smear portion is supported; A slide tray part disposed at one side of the smearing part and provided to receive the slide to be grip-moved to the smearing part, and arranged to position the slide before smearing and the slide after smearing in a divided space; And one side on the front and rear lines of the smear part, and moves up and down in the state of gripping the slide housed in the slide tray part and supplied to be supported by the smear part by rotation. And a slide grip part installed to recover the slide tray part again in a gripped state.

The inspection tray may include a container storage groove in which the container and the filter are disposed to be accommodated, and the container is inserted and stored to accommodate the container and the filter in a row at a plurality of radial positions. A main tray body having a tray space in the center of a disk shape having a filter housing groove in which a filter is accommodated; A sub tray body disposed at the center of the main tray body and having a pipette storage groove in which the pipette is inserted and received at a plurality of radial positions so as to be aligned with the container storage groove and the filter storage groove; A rotation plate disposed below the main tray body and the sub tray body and supporting the main tray body and the sub tray body to rotate together; A tray rotating shaft disposed below the rotating plate, the tray rotating shaft being provided in an axial form to transmit power to the rotating plate; And a tray rotating motor disposed under the tray rotating shaft and providing power for rotating the tray rotating shaft.

The main grip part is disposed at a rear surface of the test tray part on the left and right moving lines, and moves from the upper part of the test tray part to the upper part of the smear part in the left and right directions according to the transfer positions of the container, the filter, and the pipette. Left and right transfer module provided to make; It is disposed on the front of the left and right transfer module, the left and right transfer body provided in the form of a bracket fixed to the left and right transfer module to be transferred to the left and right; A shanghai transport module disposed on the front of the left and right transport bodies and provided to move up and down at a position of the left and right transport bodies moved left and right by the operation of the left and right transport modules; A shanghai song body disposed on the front side of the shanghai song module, provided in a bracket shape fixed to the shanghai song module and transported up and down, and installed with the pipette operating part on one side to move together up, down, left and right; Rotation support is disposed in the center of the front surface of the shanghai Song body, and supported to rotate in the horizontal direction from the bottom; A rotation motor disposed on an upper portion of the rotatable support and providing power to be rotated in a horizontal direction at a lower portion thereof; A rotating shaft protruding from the lower portion of the rotating motor and transmitting a rotating force to the lower portion through the rotating support; A main gripper driving body which is supported by the lower part of the rotating shaft and is rotated by the operation of the rotating motor while providing a grip force for adjusting the gap from the center to both sides; And a lower portion of the main gripper driver, and provided in plural in order to grip the cylindrical container and the filter in a radial position, the gap being moved by the operation of the main gripper driver while being moved left, right, up and down. It may include; main gripper for performing the grip operation while being adjusted.

In addition, the pipette operating portion is disposed on one side of the main grip portion, the pipette support for supporting in a fixed state to move left and right and up and down with the main grip portion; The pipette support is supported to be movable up and down, and is provided in a hollow form so that pneumatic pressure is applied to the inside while moving together with the main grip part, and a pipette support ring is installed to support the pipette downward. A pipette insert which is detached by insertion of the pipette placed in and sucks the liquid cells of the container and dispenses at the smeared position; A pipette vertical transfer module disposed on one side of the main grip part and fixed to the pipette insert on one side of the pipette support to move up and down; A pneumatic connecting tube connected to an upper portion of the pipette insert, and connected to supply air pressure to suck and discharge the pipette insert; A pneumatic cylinder disposed on one side of the main grip part and connected to the pneumatic connection tube to generate air pressure for suction or discharge; A pneumatic piston disposed in the pneumatic cylinder and reciprocating to adjust the pressure of suction or discharge according to a moving direction while moving in the pneumatic cylinder; A piston transfer block disposed on one side of the pneumatic piston and connected to the pneumatic piston; And a piston motor fixed to the piston transfer block and providing a reciprocating power of the pneumatic piston to move the piston transfer block.

In addition, the smear unit is disposed on one side lower portion of the main grip portion, the smear body having a filter insertion hole which is located on one side of the inspection tray portion is a through-hole through which the filter is transferred to the main grab portion; A fastening protrusion disposed inside the smear body, the fastening protrusion protruding in a spiral from the inner wall of the filter inserting hole in a center direction to be fastened and disassembled by rotation of the filter; And a smear supporter disposed under the smear body, the smear support supporting the liquid cell passing through the filter by placing the slide transferred to the slide grip part under the filter inserting hole. .

In addition, the slide tray portion is disposed on the front surface of the smear portion, the upper portion is opened therein has a settling space to be settled in the state in which the slide is accommodated, the partition partition partitioning the space into the center of the settling space One side of the installed and partitioned slide tray body is placed before the slide is placed, the other side the slide is placed after the smear; And a slide settle body disposed inside the slide tray body and disposed on both sides of the settle space facing each other and having slide inserting grooves in a plurality of positions such that both ends of the slide are inserted and settled. have.

The slide grip part may include a front and rear transfer module which is disposed in front of the forward and backward line of the smear portion and is provided to move along the front and rear direction from the position in which the slide is accommodated to the slide settle position of the smear portion; A slide transfer body disposed on the right side of the front and rear transfer module and provided in a bracket shape fixed to the front and rear transfer module and transferred back and forth; Shanghai conveying means is disposed on the right side of the slide transfer body, provided to move up and down on the right side of the slide transfer body; Is disposed on the right side of the Shanghai transport means, the Shanghai transport support is fixed to the Shanghai transport means and provided in the form of a bracket to be transported up and down; A gripper rotating motor disposed on a right side of the shanghai conveying support, the gripper rotating motor being fixed to the shanghai conveying support and being fed together; A gripper support body disposed on a right side of the gripper rotation motor and provided in a bracket shape fixed to the gripper rotation motor and rotating in a vertical direction; A gripper actuator disposed on one side of the gripper support member and fixed to the gripper support member so as to be rotated back and forth, up and down, and rotated, the gripper actuator providing a grip force for adjusting a gap from the center to both sides; And a pair disposed on one side of the gripper actuator to face each other, the grip being transferred to the smearing part while the gap is adjusted by the operation of the gripper actuator, and the smearing finish on the smearing part. A slide gripper for recovering the slide; may include.

Specific details for achieving the above object will be apparent with reference to the embodiments described below in detail with the accompanying drawings.

However, the present invention is not limited to the embodiments disclosed below, but may be configured in a variety of different forms, the present embodiments to ensure that the disclosure of the present invention is complete and the container knowledge in the technical field to which the present invention belongs It is provided to fully inform those who have the scope of the invention.

According to one of the aforementioned problem solving means of the present invention, the automatic liquid cell smearing device according to an embodiment of the present invention, when performing the liquid smearing of the liquid sample, at the same time the solution container containing the sample and the solution solution, the filter, and the suction pipette Dispensing is carried out while feeding and moving to the location to be smeared, and after supplying the slide in a gripped state, it is recovered after the smearing, and the slide smearing process is easily and automatically performed, thereby providing an effect of improving inspection efficiency.

In addition, the automatic liquid cell smearing device according to an embodiment of the present invention is supplied by feeding a plurality of filters, containers, pipettes to the side at the center of the smearing portion at the same time by suction dispensing while transferring to a single device, the slide portion in the state By dividing before and after smearing, the process of inhaling and dispensing liquid cells and simplifying the process of transporting and smearing slides provide an effect of improving inspection efficiency.

1 is a perspective view showing an automatic liquid cell smear device according to an embodiment of the present invention.
FIG. 2 is a partially cutaway perspective view of the automatic liquid cell smear device of FIG. 1. FIG.
3 is a plan view showing an inspection tray which is a main part of the automatic liquid cell smearing apparatus of FIG. 1.
FIG. 4 is a front view showing an inspection tray which is a main part of the automatic liquid cell smearing apparatus of FIG. 1.
FIG. 5 is a front view illustrating a main grip part and a pipette operation part which are main parts of the automatic liquid cell smearing apparatus of FIG. 1.
FIG. 6 is a perspective view illustrating a state in which the main grip part and the pipette operating part which are main parts of the automatic liquid cell smearing device of FIG. 1 are operated.
FIG. 7 is a diagram illustrating a state of use of the automatic liquid cell smear apparatus of FIG. 1, which is moved to an upper portion of the smear unit while the filter is gripped.
8 is a use state diagram showing a state in which the pipette operating portion of the automatic liquid cell smearing apparatus of FIG.
9 is a block diagram showing a part of the configuration of the pipette operating portion of the main portion of the automatic liquid cell smear device of FIG.
10 is a use state diagram showing a state in which the filter of the automatic liquid cell smear device of FIG. 1 is installed in the smear unit.
FIG. 11 is a perspective view illustrating a state of use of a slide tray part and a slide grip part, which are main parts of the automatic liquid cell smear apparatus of FIG. 1.
FIG. 12 is a use state diagram illustrating a state in which the slide of the automatic liquid cell smear apparatus of FIG. 11 is rotated and mounted on the smear unit.

DETAILED DESCRIPTION The present invention may be modified in various ways and may have various embodiments. Specific embodiments are illustrated in the drawings and described in detail with reference to the accompanying drawings. However, this is not intended to limit the present invention to specific embodiments, it should be understood to include all modifications, equivalents, and substitutes included in the spirit and scope of the present invention.

In describing the present invention, when it is determined that the detailed description of the related known technology may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted. In addition, numerals (eg, first, second, etc.) used in the description process of the present specification are merely identification symbols for distinguishing one component from another component.

In addition, in the present specification, when one component is referred to as "connected" or "connected" with another component, the one component may be directly connected or directly connected to the other component, but in particular It is to be understood that, unless there is an opposite substrate, it may be connected or connected via another component in the middle.

The suffixes "module" and "unit" for components used in the following description are given or used in consideration of ease of specification, and do not have distinct meanings or roles from each other. In addition, in order to clearly describe the present invention, parts irrelevant to the description are omitted in the drawings, and the width, length, thickness, etc. of the components in the drawings may be exaggerated for convenience. Like reference numerals denote like elements throughout the specification.

Hereinafter, with reference to the accompanying drawings will be described in detail for the practice of the present invention.

1 is a perspective view showing an automatic liquid cell smear device according to an embodiment of the present invention, Figure 2 is a partially cutaway perspective view showing the automatic liquid cell smear device of Figure 1, Figure 3 is an automatic liquid cell smear device of Figure 1 4 is a plan view illustrating a test tray part, which is a main part of FIG. 1, and FIG. 4 is a front view showing a test tray part, which is a main part of the automatic liquid cell smear device of FIG. 1, and FIG. 5 is a main grip part of a main part of the automatic liquid cell smear device of FIG. 6 is a front view showing a pipette operating part, and FIG. 6 is a perspective view of a main grip part and a pipette operating part which are main parts of the automatic liquid cell smearing device of FIG. 1, and FIG. Fig. 8 is a use state diagram showing a state in which the filter is gripped and moved to an upper portion of the smear unit. Fig. 9 is a configuration diagram showing a part of the pipette operating part, which is a main part of the automatic liquid cell smearing apparatus of Fig. 1, and FIG. 10 is an automatic liquid cell smearing apparatus of Fig. 1. Fig. 11 is a use state diagram showing a state in which the filter is installed in the smearing portion, and Fig. 11 is a perspective view showing the use of the slide tray and the slide grip portion, which are main parts of the automatic liquid cell smearing apparatus of Fig. It is a use state diagram which shows the state in which the slide of a cell smear apparatus is rotated and attached to a smear part.

1 to 12, the automatic liquid cell smearing device 100 according to an embodiment of the present invention is a pipette 30 from a container 10 containing liquid cells including test cells and a solution solution. It is a device that spreads on the slide 40 after the suction is dispensed and filtered by the filter 20.

The automatic liquid cell smearing device 100 includes a test tray unit 110, a main grip unit 120, a pipette operating unit 130, a smear containing a container 10, a pipette 30, and a filter 20. The unit 140, a slide tray unit 150, and a slide grip unit 160 are included.

The inspection tray unit 110 is accommodated in a row in the container 10, the pipette 30 and the filter 20 in a plurality of radial positions, respectively, and provided to rotate in accordance with the supply position.

The inspection tray unit 110 includes a main tray body 111, a sub tray body 115, a rotating plate 117, a tray rotating shaft 118, and a tray in which the container 10 and the filter 20 are placed. Rotating motor 119 is included.

The main tray body 111 is disposed so that the container 10 and the filter 20 are accommodated therein, and the container 10 is arranged to receive the container 10 and the filter 20 in a row at a plurality of radial positions. It has a container storage groove 112 to be inserted and received, and has a tray shape 114 in a disk shape having a filter housing groove 113 in which the filter 20 is accommodated, the space in which the pipette 30 is accommodated. do.

That is, the main tray body 111 is radially aligned in the center by the rotation in consideration of the transfer position of the main grip unit 120 in which the radial position in which the container 10 and the filter 20 are received is transferred to the left and right sides. The container housing groove 112 and the filter housing groove 113 are provided to be in the position of the container 10 and the filter 20 is formed in the shape of a disc to be placed.

The sub tray body 115 is disposed in the center of the main tray body 111 and the pipette 30 is inserted and received at a plurality of radial positions so as to be aligned with the container storage groove 112 and the filter storage groove 113. It has a pipette receiving groove 116. That is, as the pipette 30 is pressed to the sub-tray body 115 by the operation of the pipette operating unit 130, the pipette 30 is independently separated from the filter 20 and the container 10 at a position apart from the filter 10. The pipette storage groove 116 is formed at a plurality of radial positions so as to be placed in the same row as the plurality of vessels 10 and filters 20 which are placed and placed.

The rotation plate 117 is disposed below the main tray body 111 and the sub tray body 115, and is provided to support the main tray body 111 and the sub tray body 115 to rotate together.

The tray rotating shaft 118 is disposed below the rotating plate 117, and is provided in a shaft form to transmit power that is rotated to the rotating plate 117.

The tray rotating motor 119 is disposed below the tray rotating shaft 118 and is provided to provide power for rotating the tray rotating shaft 118. Here, the tray rotation motor 119 is set to the angle to be rotated to one of the plurality of radial rows to be aligned so that the container 10, the filter 20, and the pipette 30 is transferred for smearing the next Rows of vessel 10, filter 20, and pipette 30 may be provided with a stepping motor that rotates step by step to be positioned.

The main grip part 120 is disposed on one side on the left and right lines of the test tray part 110 and is gripped to a position where the filter 20 accommodated in the test tray part 110 is installed while moving to the left, right, up and down, and rotated. It is driven to move up, down, left and right in one state and installed by rotation, and is provided to move to a position where the pipette 30 is suctioned and dispensed.

The main grip part 120 includes a left and right transport module 121 for transporting the container 10, the filter 20, and the pipette 30 from side to side, the left and right transport body 122, the Shanghai transport module 123, and the Shanghai transport body. 124, the rotation support 125, the rotation motor 126, the rotation shaft 127, the main gripper driver 128, and the main gripper 129.

The left and right transfer module 121 is disposed on the rear of the left and right moving line of the main tray body 111, the container 10, the filter 20 from the upper portion of the main tray body 111 to the upper portion of the smearing portion 140 And it is provided to move in the left and right direction according to the transport position of the pipette (30).

The left and right conveying body 122 is disposed on the front of the left and right conveying module 121, is fixed to the left and right conveying module 121 is provided in the form of a bracket which is transferred to the left and right.

Shanghai transport module 123 is disposed on the front of the left and right transport body 122, it is provided to move up and down at the position of the left and right transport body 122 moved to the left and right by the operation of the left and right transport module 121. .

Shanghai Song body 124 is disposed on the front of the Shanghai Song module 123, is fixed to the Shanghai Song module 123 is provided in the form of a bracket to be transported up and down, pipette operation unit to move together up, down, left and right on one side 130 is installed.

The rotary support 125 is disposed in the center of the front surface of the shanghai Song body 124, it is provided to support the rotation in the horizontal direction from the bottom.

The rotary motor 126 is disposed above the rotary support 125 and is installed to provide power to be rotated in the horizontal direction at the bottom thereof.

The rotating shaft 127 protrudes from the lower portion of the rotating motor 126 and is provided to transmit the rotating force to the lower portion through the rotating support 125.

The main gripper driver 128 is supported at the lower portion of the rotation shaft 127 and is provided to be rotated by the operation of the rotation motor 126 while providing a grip force to adjust the gap from the center to both sides.

The main gripper 129 is disposed below the main gripper driver 128 and is provided in plural in order to grip the cylindrical container and the filter in the radial position. The gap is adjusted by the operation of the) is provided to perform the grip operation.

When the filter 20 placed in the main tray body 111 is positioned above the main tray body 111 by the operation of the left and right transport module 121, the filter 20 is lowered by the operation of the shanghai transport module 123 to maintain the main gripper driving body. An operation of 128 causes the main gripper 129 to grip the upper portion of the filter 20. When the filter 20 is gripped, the Shanghai transport module 123 is operated to lift the upper portion, and then the upper and lower portions of the smear 140 are moved by the left and right transport module 121 and then rotated with the Shanghai transport module 123. The filter 20 is installed in the smear section 140 while lowering and rotating by the operation of the motor 126.

Here, the pipette operation unit 130 is a position in which the pipette 30 placed in the sub-tray body 115 is inserted and supported, a position to suck the liquid cells from the container 10, a filter installed in the smear unit 140 after the suction 20 is moved left and right, up and down to the left and right transport module 121 and the Shanghai transport module 123 to move to the position for dispensing the liquid cells, and the position to remove the inserted pipette 30 after dispensing the liquid cells. It is fixedly installed on one side of the shanghai Song body 124.

Pipette operation unit 130 is disposed on one side of the main grip portion 120, while moving along with the main grip portion 120, the pipette 30 received by the action of the air pressure is removed by the suction and dispensing the liquid cells It is provided to.

Pipette operation unit 130 is installed on one side of the shanghai body 124 pipette support 131, pipette inserting body 132, pipette up and down transport module 134 to be conveyed together up, down, left and right, pneumatic connection tube 135 ), A pneumatic cylinder 136, a pneumatic piston 137, a piston transfer block 138, and a piston motor 139.

Pipette support 131 is disposed on one side of the Shanghai Song body 124, and is provided to support in a fixed state to move left and right and up and down with the Shanghai Song body 124.

The pipette insert 132 is supported by the pipette support 131 so as to be movable up and down, and is provided in a hollow form so that pneumatic pressure is applied to the inside while moving up, down, left and right with the shanghai body 124. The pipette support ring 133 is inserted into the support 30 is inserted and detached by the insertion of the pipette 30 placed in the sub-tray body 115 while sucking the liquid cells of the container 10 to the smear portion 140 It is arranged to dispense in position.

Pipette vertical transfer module 134 is disposed on one side of the shanghai Song body 124, is fixed to one side of the pipette support 131 is installed to move up and down on the pipette insert (132).

Referring to Figure 8, the pipette insert 132 shown in (a) by the operation of the left and right transfer module 121 and the Shanghai transport module 123, as shown in (b), Shanghai Song body 124 ) Is moved to the upper part of the pipette 30 accommodated in the sub-tray body 115 in a state of being supported. After the pipette insert 132 is moved to the top of the pipette 30, the pipette 30 is lowered by the operation of the pipette up and down module 134, and as shown in (c), the pipette 30 is inserted and supported and lifted upwards. In one state it is positioned to the top of the container (10). When the pipette insert 132 in which the pipette 30 is inserted into the upper portion of the container 10 is positioned by the left and right transport module 121 and the shanghai transport module 123, the pipette vertical transport module 134 operates. The pipette 30 is lowered and transferred to the suction position. After inhaling the liquid cells, the filter 20 is transferred to the smear section 140 where the filter 20 is installed and dispensed into the liquid cells. After dispensing the liquid cells, the pipette 30 is transferred to a position in which the pipette 30 is removed in the reverse order of the operation of the pipette operation unit 132 shown in FIG.

The pneumatic connection tube 135 is connected to the upper portion of the pipette insert 132, and is connected to supply the air pressure to the suction and discharge of the pipette insert (132).

The pneumatic cylinder 136 is disposed on one side of the shanghai body 124, is connected to the pneumatic connection tube 135 is provided to generate the air pressure to suck or discharge.

The pneumatic piston 137 is disposed inside the pneumatic cylinder 136, and is provided to adjust the suction or discharge pressure according to the movement direction while moving in the pneumatic cylinder 136 by a reciprocating motion.

The piston transfer block 138 is disposed on one side of the pneumatic piston 137, is connected to the pneumatic piston 137 is provided to be transferred together.

The piston motor 139 is fixed to the piston transfer block 138 and is provided to move the piston transfer block 138 by providing reciprocating power of the pneumatic piston 137.

The pneumatic cylinder 136 connected to the pipette insert 132 and the pneumatic connecting tube 135 provides a pressure to be sucked or discharged by the operation of the pneumatic piston 137, the suction rate and the rate of dispensing the liquid cells , And the pneumatic piston 137 supported by the piston transfer block 138 by the operation of the piston motor 139 to adjust the strength of the pneumatic pressure ejected when removing the pipette 30 inserted into the pipette insert 132. Adjust the travel distance.

The smear unit 140 is disposed below one side of the main gripper 129, and is provided to insert and insert the filter 20, which is gripped and transported by the main gripper 129 at the center thereof, and is sucked by the pipette operation unit 130. The slide 40 is installed at the lower portion so as to dispense the liquid cells, thereby performing smear work.

The smear unit 140 includes a smear body 141, a fastening protrusion 143, and a smear support body 144 in which liquid cells are dispensed for smearing on the left side of the main tray body 111.

The smear body 141 is disposed on the lower side of one side of the main gripper 129, is located on the left side of the main tray body 111 is a through-hole that is inserted into the filter 20 to be transferred to the main gripper 129 in the center It has a filter insertion hole 142.

The fastening protrusion 143 is disposed inside the smear body 141 and protrudes in a spiral from the inner wall of the filter insertion hole 142 in the center direction to be fastened and disassembled by the rotation of the filter 20.

The smear support 144 is disposed below the smear body 141 and slides 40 which are grip-transferred to the slide grip part 160 to the lower part of the filter inserting hole 142 to pass through the filter 20. It is provided to support the liquid cells to smear.

The slide tray 150 is disposed on the front surface of the smear support 144 and is provided to accommodate the slide 40 which is grip-moved by the smear support 144, and the slide 40 before smearing and the slide after smearing ( 40) are provided to be located in each divided space.

The slide tray unit 150 includes a slide tray body 151 in which the slide 40 is housed, and a slide settled body 154.

The slide tray body 151 is disposed on the front surface of the smear support 144 and has an upper space therein and a settling space 152 which is settled in a state where the slide 40 is accommodated, and settled space 152. The partition partition 153 for dividing the space into the center of the partition is installed so that one side of the pre-slide slide 40 is placed, the other side is provided so that the slide 40 after the smear.

The slide settled body 154 is disposed inside the slide tray body 151 and is disposed on both sides of the settled space 152 facing each other so that both ends of the slide 40 are inserted and placed in a plurality of positions. It is provided to have an insertion groove 155. The slide settlement body 154 is inserted into and supported in the slide insertion groove 155 so as to maintain a gap in which a plurality of slides 40 having a glass shape can be gripped by the slide grip part 160. Easily withdrawal and withdrawal can improve storage efficiency.

The slide grip part 160 is disposed on one side of the front and rear lines of the smearing part 140, and is supplied to be supported by the smearing part 140 by rotation by moving up and down and up and down while the received slide 40 is gripped. After the smearing, the slide 40 is installed to be recovered again to the position where it is stored in the gripped state.

The slide grip unit 160 includes a front and rear transfer module 161, a slide transfer body 162, a shanghai transport means 163, a shanghai transport support 164, a gripper rotary motor 165, and a gripper for transporting the slide 40 back and forth. A support 166, a gripper actuator 167, and a slide gripper 168.

The front and rear transfer module 161 is disposed in front of the forward and backward movement line of the smear support 144 and moves along the front and rear direction from the position in which the slide 40 is received to the slide settle position of the smear support 144. It is provided.

The slide transfer body 162 is disposed on the right side of the front and rear transfer module 161 and is provided in the form of a bracket fixed to the front and rear transfer module 161 and transferred back and forth.

Shanghai conveying means 163 is disposed on the right side of the slide transfer body 162, it is provided to transfer up and down on the right side of the slide transfer body 162.

Shanghai transport support 164 is disposed on the right side of the Shanghai transport means 163, is fixed to the Shanghai transport means 163 is provided in the form of a bracket that is transported up and down.

The gripper rotary motor 165 is disposed on the right side of the shanghai conveying support 164 and is fixed to the shanghai conveying support 164 and installed to provide a rotational force that is rotated in a vertical direction.

The gripper support 166 is disposed on the right side of the gripper rotary motor 165 and is provided in the form of a bracket fixed to the gripper rotary motor 165 to be rotated in the vertical direction.

The gripper actuator 167 is disposed on one side of the gripper support 166 and is fixed to the gripper support 166 so as to be rotated back, front, up, and down, and is installed to provide a grip force that adjusts a gap from the center to both sides.

The slide gripper 168 is disposed on one side of the gripper actuator 167 and is provided as a pair facing each other to grip the slide 40 while adjusting the gap by the operation of the gripper actuator 167. 144 and the slide support 144 is installed to recover the finished slide 40.

The above description is merely illustrative of the technical idea of the present invention, and those skilled in the art to which the present invention pertains may make various modifications and changes without departing from the essential characteristics of the present invention.

Therefore, the embodiments disclosed in the present invention are not intended to limit the technical idea of the present invention but to describe the present invention, and the scope of the technical idea of the present invention is not limited by these embodiments.

The protection scope of the present invention should be interpreted by the following claims, and all technical ideas within the equivalent scope should be interpreted as being included in the scope of the present invention.

<Description of the symbols for the main parts of the drawings>
100: smear device 110: inspection tray
111: main tray body 112: container storage groove
113: filter storage groove 114: tray space
115: sub tray body 116: pipette receiving groove
117: rotating plate 118: tray rotating shaft
119: tray rotation motor 120: main grip
121: left and right transfer module 122: left and right transfer body
123: Shanghai Song module 124: Shanghai Song body
125: rotating support 126: rotating motor
127: rotation axis 128: main gripper drive body
129: main gripper 130: pipette operating part
131: pipette support 132: pipette insert
133: pipette support ring 134: pipette vertical transfer module
135: pneumatic connection tube 136: pneumatic cylinder
137: pneumatic piston 138: piston feed block
139: piston motor 140: smear
141: smear body 142: filter insertion hole
143: fastening protrusion 144: smear support
150: slide tray unit 151: slide tray body
152: settled space 153: partition bulkhead
154: slide settlement 155: slide insertion groove
160: slide grip 161: front and rear transfer module
162: slide conveying body 163: Shanghai transport means
164: Shanghai Song support 165: gripper rotary motor
166: gripper support 167: gripper actuator
168: Slide Gripper

Claims (7)

In the automatic liquid cell smearing device, which is aspirated by a pipette in a container containing a test cell and a liquid cell containing a solution solution, filtered by a filter, and then smeared on a slide,
An inspection tray part accommodating the container, the pipette and the filter in a plurality of positions in a radial position, and rotating according to a supply position;
It is disposed on one side on the left and right lines of the inspection tray portion, and moved to the left and right, up and down, and rotated so as to be installed by rotating by moving up, down, left and right in a state where the filter accommodated in the inspection tray is installed. A main grip part driven to move to a position where the pipette is sucked and a dispensed position;
A pipette operation part disposed on one side of the main grip part and configured to suck and dispense liquid cells while the pipette is detached and detached by the action of air pressure while being moved together with the main grip part;
The slide is disposed at one lower side of the main grip part, and the filter is inserted into and mounted at the center of the main grip part, and the slide is disposed at the lower part so as to dispense the liquid cells sucked from the pipette operation part to perform smearing. Smear portion is supported;
A slide tray part disposed at one side of the smearing part and provided to receive the slide to be grip-moved to the smearing part, and arranged to position the slide before smearing and the slide after smearing in a divided space; And
It is disposed on one side on the front and back line of the smearing part, and moves up and down vertically in a state in which the slide housed in the slide tray part is gripped to be supplied to be supported by the smearing part by rotation. Including a slide grip unit installed to recover the slide tray in one state; including,
The smear unit,
A smear body disposed at one lower side of the main grip part and having a filter inserting hole which is located on one side of the inspection tray part and is a through hole in which the filter is transferred to the main grip part in the center;
A fastening protrusion disposed inside the smear body, the fastening protrusion protruding in a spiral from the inner wall of the filter inserting hole in a center direction to be fastened and disassembled by rotation of the filter; And
It is disposed on the lower portion of the smear body, a smear support for supporting the liquid cell passed through the filter is placed in the slide that is transferred to the slide grip portion to the lower portion of the filter insertion hole;
Automatic liquid cell smear device.
The method of claim 1,
The inspection tray unit,
The container and the filter are arranged to be accommodated in the housing, and the container and the container receiving groove into which the container is inserted and housed so as to receive the container and the filter in a row in a plurality of radial positions, respectively, the filter storage groove in which the filter is accommodated A main tray body having a tray space that is a space in which the pipette is accommodated in a disk shape having a center;
A sub tray body disposed at the center of the main tray body and having a pipette storage groove in which the pipette is inserted and received at a plurality of radial positions so as to be aligned with the container storage groove and the filter storage groove;
A rotation plate disposed below the main tray body and the sub tray body and supporting the main tray body and the sub tray body to rotate together;
A tray rotating shaft disposed below the rotating plate, the tray rotating shaft being provided in an axial form to transmit power to the rotating plate; And
It is disposed below the tray rotating shaft, the tray rotating motor for providing power for rotating the tray rotating shaft; including
Automatic liquid cell smear device.
The method of claim 1,
The main grip portion,
It is disposed on the rear of the left and right moving line of the inspection tray portion, and the left and right transfer module is provided to move in the left and right direction according to the transfer position of the container, the filter, and the pipette from the upper portion of the inspection tray portion to the upper portion of the smearing portion. ;
It is disposed on the front of the left and right transfer module, the left and right transfer body provided in the form of a bracket fixed to the left and right transfer module to be transferred to the left and right;
A shanghai transport module disposed on the front of the left and right transport bodies and provided to move up and down at a position of the left and right transport bodies moved left and right by the operation of the left and right transport modules;
A shanghai song body disposed on the front side of the shanghai song module, provided in a bracket shape fixed to the shanghai song module and transported up and down, and installed with the pipette operating part on one side to move together up, down, left and right;
Rotation support is disposed in the center of the front surface of the shanghai Song body, and supported to rotate in the horizontal direction from the bottom;
A rotation motor disposed on an upper portion of the rotatable support and providing power to be rotated in a horizontal direction at a lower portion thereof;
A rotating shaft protruding from the lower portion of the rotating motor and transmitting a rotating force to the lower portion through the rotating support;
A main gripper driving body which is supported by the lower part of the rotating shaft and is rotated by the operation of the rotating motor while providing a grip force for adjusting the gap from the center to both sides; And
It is disposed under the main gripper driving body, and provided in plurality in a radial position to grip the container and the filter in a radial position, the gap is adjusted by the operation of the main gripper driving body while moving left, right, up and down. Comprising a main gripper for performing a grip operation;
Automatic liquid cell smear device.
The method of claim 1,
The pipette operating portion,
A pipette support member which is disposed on one side of the main grip part and supports the fixed part so as to move left and right and up and down together with the main grip part;
The pipette support is supported to be movable up and down, and is provided in a hollow form so that pneumatic pressure is applied to the inside while moving together with the main grip part, and a pipette support ring is installed to support the pipette downward. A pipette insert which is detached by insertion of the pipette placed in and sucks the liquid cells of the container and dispenses at the smeared position;
A pipette vertical transfer module disposed on one side of the main grip part and fixed to one side of the pipette support to move the pipette insert up and down;
A pneumatic connecting tube connected to an upper portion of the pipette insert, and connected to supply air pressure to suck and discharge the pipette insert;
A pneumatic cylinder disposed on one side of the main grip part and connected to the pneumatic connection tube to generate air pressure for suction or discharge;
A pneumatic piston disposed in the pneumatic cylinder and reciprocating to adjust the pressure of suction or discharge according to a moving direction while moving in the pneumatic cylinder;
A piston transfer block disposed on one side of the pneumatic piston and connected to the pneumatic piston; And
And a piston motor fixed to the piston transfer block and providing a reciprocating power of the pneumatic piston to move the piston transfer block.
Automatic liquid cell smear device.
delete The method of claim 1,
The slide tray unit,
It is disposed on the front surface of the smearing portion, the upper portion is opened therein has a settled space is settled in the received state, the partition partition partitioning the space into the center of the settled space is installed and divided one side A slide tray body in which the slide is settled on the other side and the slide is settled on the other side; And
It is disposed inside the slide tray body, the slide settle body having a slide insertion groove in a plurality of positions so that both ends of the slide are respectively placed on both sides of the settle space is inserted into the settle;
Automatic liquid cell smear device.
The method of claim 1,
The slide grip portion,
It is disposed in front of the forward and backward movement line of the smear portion, and the front and rear transfer module is provided to move in the front and rear direction from the position where the slide is accommodated to the slide settled position of the smear portion;
A slide transfer body disposed on the right side of the front and rear transfer module and provided in a bracket shape fixed to the front and rear transfer module and transferred back and forth;
Shanghai conveying means is disposed on the right side of the slide transfer body, provided to move up and down on the right side of the slide transfer body;
Is disposed on the right side of the Shanghai transport means, the Shanghai transport support is fixed to the Shanghai transport means and provided in the form of a bracket to be transported up and down;
A gripper rotating motor disposed on a right side of the shanghai conveying support, the gripper rotating motor being fixed to the shanghai conveying support and being fed together;
A gripper support body disposed on a right side of the gripper rotation motor and provided in a bracket shape fixed to the gripper rotation motor and rotating in a vertical direction;
A gripper actuator disposed on one side of the gripper support member and fixed to the gripper support member so as to be rotated back and forth, up and down, and rotated, the gripper actuator providing a grip force for adjusting a gap from the center to both sides; And
The slide is disposed on one side of the gripper actuator, and provided in a pair facing each other, the slide is gripped and transferred to the smearing part while the gap is adjusted by the operation of the gripper actuator, and the slide finishes the smearing on the smearing part. Comprising; a slide gripper for recovering
Automatic liquid cell smear device.

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