KR20190017767A - C-raf 억제제의 치료적 용도 - Google Patents
C-raf 억제제의 치료적 용도 Download PDFInfo
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- KR20190017767A KR20190017767A KR1020187035219A KR20187035219A KR20190017767A KR 20190017767 A KR20190017767 A KR 20190017767A KR 1020187035219 A KR1020187035219 A KR 1020187035219A KR 20187035219 A KR20187035219 A KR 20187035219A KR 20190017767 A KR20190017767 A KR 20190017767A
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| CN110494166B (zh) | 2017-05-02 | 2022-11-08 | 诺华股份有限公司 | 组合疗法 |
| EP3965710A4 (en) | 2019-03-08 | 2023-04-05 | Auris Health, Inc. | TILT MECHANISMS FOR MEDICAL SYSTEMS AND APPLICATIONS |
| KR102881316B1 (ko) | 2019-05-13 | 2025-11-05 | 노파르티스 아게 | 암 치료를 위한 raf 억제제로서의 n-(3-(2-(2-하이드록시에톡시)-6-모르폴리노피리딘-4-일)-4-메틸페닐)-2 (트리플루오로메틸)이소니코틴아미드의 새로운 결정질 형태 |
| PH12022550976A1 (en) | 2019-10-24 | 2023-09-25 | Kinnate Biopharma Inc | Inhibitors of raf kinases |
| US20230046018A1 (en) * | 2019-12-06 | 2023-02-16 | Medshine Discovery Inc. | Biaryl compound as pan-raf kinase inhibitor |
| CN113912591B (zh) * | 2020-07-08 | 2023-10-20 | 齐鲁制药有限公司 | 联芳基化合物 |
| TWI812259B (zh) * | 2021-06-04 | 2023-08-11 | 大陸商齊魯製藥有限公司 | Raf激酶抑制劑的晶型及其製備方法 |
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| WO2025255438A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
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| AR090151A1 (es) * | 2012-03-07 | 2014-10-22 | Lilly Co Eli | Compuestos inhibidores de raf |
| US9242969B2 (en) * | 2013-03-14 | 2016-01-26 | Novartis Ag | Biaryl amide compounds as kinase inhibitors |
| TWI681969B (zh) * | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對pd-1的人類抗體 |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| EP3102605B1 (en) * | 2014-02-04 | 2018-11-14 | Pfizer Inc | Combination of a pd-1 antagonist and a vegfr inhibitor for treating cancer |
| CA2954508A1 (en) * | 2014-07-15 | 2016-01-21 | Genentech, Inc. | Compositions for treating cancer using pd-1 axis binding antagonists and mek inhibitors |
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2017
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- 2017-06-08 EP EP17733028.9A patent/EP3468595A1/en not_active Withdrawn
- 2017-06-08 US US16/307,920 patent/US20190175609A1/en not_active Abandoned
- 2017-06-08 BR BR112018075371-8A patent/BR112018075371A2/pt not_active Application Discontinuation
- 2017-06-08 KR KR1020187035219A patent/KR20190017767A/ko not_active Ceased
- 2017-06-08 RU RU2018146886A patent/RU2018146886A/ru not_active Application Discontinuation
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- 2017-06-08 MX MX2018015353A patent/MX2018015353A/es unknown
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- 2017-06-08 CA CA3026876A patent/CA3026876A1/en not_active Abandoned
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| JP2019517549A (ja) | 2019-06-24 |
| IL262961A (en) | 2018-12-31 |
| AU2017279046B2 (en) | 2020-07-02 |
| RU2018146886A (ru) | 2020-07-10 |
| US20190175609A1 (en) | 2019-06-13 |
| WO2017212442A1 (en) | 2017-12-14 |
| CA3026876A1 (en) | 2017-12-14 |
| AU2017279046A1 (en) | 2018-12-06 |
| RU2018146886A3 (enExample) | 2020-10-15 |
| CL2018003530A1 (es) | 2019-02-15 |
| BR112018075371A2 (pt) | 2019-03-19 |
| MX2018015353A (es) | 2019-09-09 |
| EP3468595A1 (en) | 2019-04-17 |
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