CA3026876A1 - Therapeutic uses of a c-raf inhibitor - Google Patents
Therapeutic uses of a c-raf inhibitor Download PDFInfo
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- CA3026876A1 CA3026876A1 CA3026876A CA3026876A CA3026876A1 CA 3026876 A1 CA3026876 A1 CA 3026876A1 CA 3026876 A CA3026876 A CA 3026876A CA 3026876 A CA3026876 A CA 3026876A CA 3026876 A1 CA3026876 A1 CA 3026876A1
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| US201662348720P | 2016-06-10 | 2016-06-10 | |
| US62/348,720 | 2016-06-10 | ||
| PCT/IB2017/053405 WO2017212442A1 (en) | 2016-06-10 | 2017-06-08 | Therapeutic uses of a c-raf inhibitor |
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| CA3026876A1 true CA3026876A1 (en) | 2017-12-14 |
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| WO2018051306A1 (en) * | 2016-09-19 | 2018-03-22 | Novartis Ag | Therapeutic combinations comprising a raf inhibitor and a erk inhibitor |
| EP4272740A1 (en) | 2017-05-02 | 2023-11-08 | Novartis AG | Combination therapy comprising a raf inhibitor and trametinib |
| CN113613612B (zh) | 2019-03-08 | 2022-08-02 | 奥瑞斯健康公司 | 用于医疗系统和应用的倾斜机构 |
| JP2022531969A (ja) | 2019-05-13 | 2022-07-12 | ノバルティス アーゲー | 癌を治療するためのＲａｆ阻害剤としてのＮ－（３－（２－（２－ヒドロキシエトキシ）－６－モルホリノピリジン－４－イル）－４－メチルフェニル）－２－（トリフルオロメチル）イソニコチンアミドの新規な結晶形態 |
| IL292424A (en) | 2019-10-24 | 2022-06-01 | Kinnate Biopharma Inc | Inhibitors of raf kinases |
| JP7214925B2 (ja) * | 2019-12-06 | 2023-01-30 | メッドシャイン ディスカバリー インコーポレイテッド | Ｐａｎ－ＲＡＦキナーゼ阻害剤としてのビアリール化合物 |
| CN113912591B (zh) * | 2020-07-08 | 2023-10-20 | 齐鲁制药有限公司 | 联芳基化合物 |
| WO2022253334A1 (zh) * | 2021-06-04 | 2022-12-08 | 南京明德新药研发有限公司 | 一种raf激酶抑制剂的晶型及其制备方法 |
| TW202508595A (zh) | 2023-05-04 | 2025-03-01 | 美商銳新醫藥公司 | 用於ｒａｓ相關疾病或病症之組合療法 |
| US20250049810A1 (en) | 2023-08-07 | 2025-02-13 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025080946A2 (en) | 2023-10-12 | 2025-04-17 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
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| AR090151A1 (es) * | 2012-03-07 | 2014-10-22 | Lilly Co Eli | Compuestos inhibidores de raf |
| US9242969B2 (en) * | 2013-03-14 | 2016-01-26 | Novartis Ag | Biaryl amide compounds as kinase inhibitors |
| TWI681969B (zh) * | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| US10570202B2 (en) * | 2014-02-04 | 2020-02-25 | Pfizer Inc. | Combination of a PD-1 antagonist and a VEGFR inhibitor for treating cancer |
| SG10202007111TA (en) * | 2014-07-15 | 2020-09-29 | Genentech Inc | Compositions for treating cancer using pd-1 axis binding antagonists and mek inhibitors |
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- 2017-06-08 CN CN201780035192.1A patent/CN109310761A/zh active Pending
- 2017-06-08 MX MX2018015353A patent/MX2018015353A/es unknown
- 2017-06-08 EP EP17733028.9A patent/EP3468595A1/en not_active Withdrawn
- 2017-06-08 BR BR112018075371-8A patent/BR112018075371A2/pt not_active Application Discontinuation
- 2017-06-08 RU RU2018146886A patent/RU2018146886A/ru not_active Application Discontinuation
- 2017-06-08 CA CA3026876A patent/CA3026876A1/en not_active Abandoned
- 2017-06-08 WO PCT/IB2017/053405 patent/WO2017212442A1/en not_active Ceased
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2018
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- 2018-12-07 CL CL2018003530A patent/CL2018003530A1/es unknown
Also Published As
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| RU2018146886A (ru) | 2020-07-10 |
| WO2017212442A1 (en) | 2017-12-14 |
| BR112018075371A2 (pt) | 2019-03-19 |
| CN109310761A (zh) | 2019-02-05 |
| IL262961A (en) | 2018-12-31 |
| RU2018146886A3 (enExample) | 2020-10-15 |
| AU2017279046A1 (en) | 2018-12-06 |
| MX2018015353A (es) | 2019-09-09 |
| US20190175609A1 (en) | 2019-06-13 |
| KR20190017767A (ko) | 2019-02-20 |
| CL2018003530A1 (es) | 2019-02-15 |
| EP3468595A1 (en) | 2019-04-17 |
| JP2019517549A (ja) | 2019-06-24 |
| AU2017279046B2 (en) | 2020-07-02 |
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