KR20180121539A - 급성 신부전의 치료에 사용하기 위한 암브리센탄 - Google Patents

급성 신부전의 치료에 사용하기 위한 암브리센탄 Download PDF

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Publication number
KR20180121539A
KR20180121539A KR1020187026495A KR20187026495A KR20180121539A KR 20180121539 A KR20180121539 A KR 20180121539A KR 1020187026495 A KR1020187026495 A KR 1020187026495A KR 20187026495 A KR20187026495 A KR 20187026495A KR 20180121539 A KR20180121539 A KR 20180121539A
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KR
South Korea
Prior art keywords
subject
administered
rti
ambriscentan
kidney
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Ceased
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KR1020187026495A
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English (en)
Korean (ko)
Inventor
이케르 나바로
사티시 칸나
Original Assignee
누리크 바이오파마슈티칼스 아게
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Publication of KR20180121539A publication Critical patent/KR20180121539A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
KR1020187026495A 2016-03-18 2017-03-20 급성 신부전의 치료에 사용하기 위한 암브리센탄 Ceased KR20180121539A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662310221P 2016-03-18 2016-03-18
US62/310,221 2016-03-18
EP16166046.9 2016-04-19
EP16166046.9A EP3235496A1 (en) 2016-04-19 2016-04-19 Treatment of acute renal failure
US201662437949P 2016-12-22 2016-12-22
US62/437,949 2016-12-22
PCT/EP2017/056476 WO2017158199A1 (en) 2016-03-18 2017-03-20 Ambrisentan for use in the treatment of acute renal failure

Publications (1)

Publication Number Publication Date
KR20180121539A true KR20180121539A (ko) 2018-11-07

Family

ID=55808404

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187026495A Ceased KR20180121539A (ko) 2016-03-18 2017-03-20 급성 신부전의 치료에 사용하기 위한 암브리센탄

Country Status (17)

Country Link
US (3) US10870021B2 (enExample)
EP (3) EP3235496A1 (enExample)
JP (1) JP7237362B2 (enExample)
KR (1) KR20180121539A (enExample)
CN (1) CN109069443A (enExample)
AU (1) AU2017235618B2 (enExample)
BR (1) BR112018067602A2 (enExample)
CA (1) CA3015432A1 (enExample)
CL (1) CL2018002638A1 (enExample)
DK (1) DK3429566T3 (enExample)
ES (2) ES2966638T3 (enExample)
HK (1) HK1259616A1 (enExample)
IL (1) IL261457B (enExample)
MX (1) MX374534B (enExample)
SG (1) SG11201808009SA (enExample)
WO (1) WO2017158199A1 (enExample)
ZA (1) ZA201805562B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3639827A1 (en) 2018-10-19 2020-04-22 Noorik Biopharmaceuticals AG Use of ambrisentan for the treatment of portal hypertension and cirrhosis
EP4142731A1 (en) * 2020-04-28 2023-03-08 Noorik Biopharmaceuticals AG Treatment of pulmonary complications of coronavirus infections
WO2021219691A1 (en) * 2020-04-29 2021-11-04 Astrazeneca Ab Dapagliflozin and ambrisentan for the prevention and treatment of covid-19

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19533023B4 (de) 1994-10-14 2007-05-16 Basf Ag Neue Carbonsäurederivate, ihre Herstellung und Verwendung
CA2695259C (en) * 2007-07-31 2016-05-24 Gilead Colorado, Inc. Metabolites and derivatives of ambrisentan
US9255931B2 (en) * 2010-06-24 2016-02-09 Morehouse School Of Medicine Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
KR20140130705A (ko) * 2012-02-29 2014-11-11 도레이 카부시키가이샤 체강액 저류 억제제
CA2901922A1 (en) * 2013-03-08 2014-09-12 Abbvie Inc. Methods of treating acute kidney injury
EP2988770A4 (en) * 2013-04-26 2016-12-14 La Jolla Pharma Co COMPOSITIONS AND METHOD FOR TREATING KIDNEY FAILURES
WO2015069839A1 (en) * 2013-11-06 2015-05-14 Gilead Sciences, Inc. Combination therapy for treating pulmonary hypertension

Also Published As

Publication number Publication date
US10870021B2 (en) 2020-12-22
AU2017235618A1 (en) 2018-09-27
IL261457A (en) 2018-10-31
DK3429566T3 (da) 2021-03-29
EP3429566A1 (en) 2019-01-23
US20210046332A1 (en) 2021-02-18
CA3015432A1 (en) 2017-09-21
ZA201805562B (en) 2019-06-26
SG11201808009SA (en) 2018-10-30
CL2018002638A1 (es) 2019-01-18
IL261457B (en) 2021-09-30
WO2017158199A1 (en) 2017-09-21
BR112018067602A2 (pt) 2019-01-08
AU2017235618B2 (en) 2021-02-25
US20190083820A1 (en) 2019-03-21
CN109069443A (zh) 2018-12-21
MX2018011222A (es) 2019-01-10
EP3878439A1 (en) 2021-09-15
EP3878439B1 (en) 2023-10-04
US11642307B2 (en) 2023-05-09
ES2856960T3 (es) 2021-09-28
ES2966638T3 (es) 2024-04-23
MX374534B (es) 2025-03-06
JP7237362B2 (ja) 2023-03-13
EP3429566B1 (en) 2021-01-27
EP3235496A1 (en) 2017-10-25
US20230233454A1 (en) 2023-07-27
HK1259616A1 (zh) 2019-12-06
NZ746140A (en) 2022-03-25
JP2019515942A (ja) 2019-06-13

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