BR112018067602A2 - ambrisentan para uso no tratamento de insuficiência renal aguda - Google Patents
ambrisentan para uso no tratamento de insuficiência renal agudaInfo
- Publication number
- BR112018067602A2 BR112018067602A2 BR112018067602A BR112018067602A BR112018067602A2 BR 112018067602 A2 BR112018067602 A2 BR 112018067602A2 BR 112018067602 A BR112018067602 A BR 112018067602A BR 112018067602 A BR112018067602 A BR 112018067602A BR 112018067602 A2 BR112018067602 A2 BR 112018067602A2
- Authority
- BR
- Brazil
- Prior art keywords
- ambrisentan
- treatment
- renal failure
- acute renal
- acute
- Prior art date
Links
- 208000009304 Acute Kidney Injury Diseases 0.000 title abstract 2
- 208000033626 Renal failure acute Diseases 0.000 title abstract 2
- 201000011040 acute kidney failure Diseases 0.000 title abstract 2
- 208000012998 acute renal failure Diseases 0.000 title abstract 2
- OUJTZYPIHDYQMC-LJQANCHMSA-N ambrisentan Chemical compound O([C@@H](C(OC)(C=1C=CC=CC=1)C=1C=CC=CC=1)C(O)=O)C1=NC(C)=CC(C)=N1 OUJTZYPIHDYQMC-LJQANCHMSA-N 0.000 title abstract 2
- 229960002414 ambrisentan Drugs 0.000 title abstract 2
- 206010047139 Vasoconstriction Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000025033 vasoconstriction Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
Abstract
a presente invenção refere-se a ambrisentan e formulações do mesmo para uso no tratamento e na prevenção de insuficiência renal aguda associada à vasoconstricção renal.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662310221P | 2016-03-18 | 2016-03-18 | |
EP16166046.9A EP3235496A1 (en) | 2016-04-19 | 2016-04-19 | Treatment of acute renal failure |
US201662437949P | 2016-12-22 | 2016-12-22 | |
PCT/EP2017/056476 WO2017158199A1 (en) | 2016-03-18 | 2017-03-20 | Ambrisentan for use in the treatment of acute renal failure |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018067602A2 true BR112018067602A2 (pt) | 2019-01-08 |
Family
ID=55808404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018067602A BR112018067602A2 (pt) | 2016-03-18 | 2017-03-20 | ambrisentan para uso no tratamento de insuficiência renal aguda |
Country Status (17)
Country | Link |
---|---|
US (3) | US10870021B2 (pt) |
EP (3) | EP3235496A1 (pt) |
JP (1) | JP7237362B2 (pt) |
KR (1) | KR20180121539A (pt) |
CN (1) | CN109069443A (pt) |
AU (1) | AU2017235618B2 (pt) |
BR (1) | BR112018067602A2 (pt) |
CA (1) | CA3015432A1 (pt) |
CL (1) | CL2018002638A1 (pt) |
DK (1) | DK3429566T3 (pt) |
ES (1) | ES2856960T3 (pt) |
HK (1) | HK1259616A1 (pt) |
IL (1) | IL261457B (pt) |
MX (1) | MX2018011222A (pt) |
SG (1) | SG11201808009SA (pt) |
WO (1) | WO2017158199A1 (pt) |
ZA (1) | ZA201805562B (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3639827A1 (en) * | 2018-10-19 | 2020-04-22 | Noorik Biopharmaceuticals AG | Use of ambrisentan for the treatment of portal hypertension and cirrhosis |
WO2021219671A1 (en) * | 2020-04-28 | 2021-11-04 | Noorik Biopharmaceuticals Ag | Treatment of pulmonary complications of coronavirus infections |
US20230165856A1 (en) * | 2020-04-29 | 2023-06-01 | Astrazeneca Ab | Dapagliflozin and ambrisentan for the prevention and treatment of covid-19 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19533023B4 (de) | 1994-10-14 | 2007-05-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
AU2008282773B8 (en) * | 2007-07-31 | 2013-03-07 | Gilead Sciences, Inc. | Metabolites and derivatives of ambrisentan |
US9255931B2 (en) * | 2010-06-24 | 2016-02-09 | Morehouse School Of Medicine | Method and compositions for the treatment and detection of endothelin-1 related kidney diseases |
CN104136038A (zh) * | 2012-02-29 | 2014-11-05 | 东丽株式会社 | 体腔积液抑制剂 |
BR112015020788A2 (pt) * | 2013-03-08 | 2017-10-10 | Abbvie Inc | métodos de tratamento da lesão renal aguda |
CA2910601A1 (en) * | 2013-04-26 | 2014-10-30 | La Jolla Pharmaceutical Company | Compositions and methods for treating renal failure |
WO2015069839A1 (en) * | 2013-11-06 | 2015-05-14 | Gilead Sciences, Inc. | Combination therapy for treating pulmonary hypertension |
-
2016
- 2016-04-19 EP EP16166046.9A patent/EP3235496A1/en not_active Withdrawn
-
2017
- 2017-03-20 EP EP17711211.7A patent/EP3429566B1/en active Active
- 2017-03-20 BR BR112018067602A patent/BR112018067602A2/pt not_active Application Discontinuation
- 2017-03-20 AU AU2017235618A patent/AU2017235618B2/en active Active
- 2017-03-20 US US16/084,340 patent/US10870021B2/en active Active
- 2017-03-20 ES ES17711211T patent/ES2856960T3/es active Active
- 2017-03-20 KR KR1020187026495A patent/KR20180121539A/ko not_active Application Discontinuation
- 2017-03-20 EP EP20175547.7A patent/EP3878439B1/en active Active
- 2017-03-20 CA CA3015432A patent/CA3015432A1/en active Pending
- 2017-03-20 DK DK17711211.7T patent/DK3429566T3/da active
- 2017-03-20 MX MX2018011222A patent/MX2018011222A/es active IP Right Grant
- 2017-03-20 JP JP2019500021A patent/JP7237362B2/ja active Active
- 2017-03-20 CN CN201780017563.3A patent/CN109069443A/zh active Pending
- 2017-03-20 WO PCT/EP2017/056476 patent/WO2017158199A1/en active Application Filing
- 2017-03-20 SG SG11201808009SA patent/SG11201808009SA/en unknown
-
2018
- 2018-08-21 ZA ZA2018/05562A patent/ZA201805562B/en unknown
- 2018-08-29 IL IL261457A patent/IL261457B/en unknown
- 2018-09-14 CL CL2018002638A patent/CL2018002638A1/es unknown
-
2019
- 2019-01-31 HK HK19101803.4A patent/HK1259616A1/zh unknown
-
2020
- 2020-10-07 US US17/065,097 patent/US11642307B2/en active Active
-
2023
- 2023-03-31 US US18/129,516 patent/US20230233454A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP7237362B2 (ja) | 2023-03-13 |
IL261457A (en) | 2018-10-31 |
EP3429566A1 (en) | 2019-01-23 |
WO2017158199A1 (en) | 2017-09-21 |
US20210046332A1 (en) | 2021-02-18 |
AU2017235618B2 (en) | 2021-02-25 |
JP2019515942A (ja) | 2019-06-13 |
EP3878439A1 (en) | 2021-09-15 |
EP3878439B1 (en) | 2023-10-04 |
US20190083820A1 (en) | 2019-03-21 |
CA3015432A1 (en) | 2017-09-21 |
HK1259616A1 (zh) | 2019-12-06 |
AU2017235618A1 (en) | 2018-09-27 |
SG11201808009SA (en) | 2018-10-30 |
NZ746140A (en) | 2022-03-25 |
KR20180121539A (ko) | 2018-11-07 |
MX2018011222A (es) | 2019-01-10 |
CL2018002638A1 (es) | 2019-01-18 |
US20230233454A1 (en) | 2023-07-27 |
US10870021B2 (en) | 2020-12-22 |
IL261457B (en) | 2021-09-30 |
ES2856960T3 (es) | 2021-09-28 |
ZA201805562B (en) | 2019-06-26 |
EP3429566B1 (en) | 2021-01-27 |
US11642307B2 (en) | 2023-05-09 |
DK3429566T3 (da) | 2021-03-29 |
CN109069443A (zh) | 2018-12-21 |
EP3235496A1 (en) | 2017-10-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SV2017005426A (es) | Derivados de feniltriazol sustituido con hidroxialquilo y sus usos | |
CO2019001193A2 (es) | Métodos y composiciones para el tratamiento de trastornos epilépticos | |
SV2018005610A (es) | Derivados de oxopiridina sustituidos | |
CL2015002891A1 (es) | Deaza-purinonas macrocíclicas para el tratamiento de infecciones virales. | |
BR112018072401A2 (pt) | combinações de linagliptina e metformina | |
BR112015023207A2 (pt) | uso de c1-inh no tratamento de desordens associadas à deficiência de inibidor de c1 esterase | |
CO2019008103A2 (es) | Composiciones farmacéuticas para terapia de combinación | |
BR112017007414A2 (pt) | combinações compreendendo siponimod e laquinimod para o tratamento de esclerose múltipla | |
BR112019009172A2 (pt) | formulações para radioterapia e diagnóstico por imagem. | |
CL2015002180A1 (es) | Terapia de combinación para el tratamiento de neumonía nosocomial | |
BR112017015159A2 (pt) | preparação e uso de produtos plaquetários | |
CL2016002151A1 (es) | Derivados de piridazina para uso en la prevención o el tratamiento de un trastorno atáxico | |
BR112018012313A2 (pt) | composições que compreendem 15-hepe e métodos para uso das mesmas | |
BR112017011168A2 (pt) | medicamentos para retardar a doença de parkinson | |
BR112016017620A2 (pt) | Composto esteroidal para uso no tratamento da encefalopatia hepática | |
CO2017011295A2 (es) | Piroglutamato de vortioxetina | |
BR112017009000A2 (pt) | apilimod para uso no tratamento de melanoma | |
BR112018067602A2 (pt) | ambrisentan para uso no tratamento de insuficiência renal aguda | |
CL2018000403A1 (es) | Compuestos para uso en aplicaciones antibacterianas. | |
BR112018005299A2 (pt) | 1,1-difeniletilenos substituídos com alquenilfenoxi, processos para sua preparação e seu uso | |
BR112017011685A2 (pt) | composições compreendendo 15-hepe e métodos de tratamento ou prevenção da fibrose usando as mesmas | |
UY36434A (es) | Nuevas formas cristalinas de la sal de monosodio del foramsulfurón | |
BR112017012400A2 (pt) | processo para fabricação de partículas de resinato de fenilefrina; partículas de resinato de fenilefrina e uso de partículas de resinato de fenilefrina em formulações farmacêuticas | |
AR114030A1 (es) | Triterpenos pentacíclicos en el tratamiento de una patología oral-dental | |
BR112016011554A2 (pt) | Uso de brometo para minimizar ou prevenir a indução de inanição relacionada ao estresse ou inanição relacionada à ansiedade em um animal durante, ou em conclusão de, uma prática de comercialização ou gestão |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |