KR20180100251A - 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료 - Google Patents

태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료 Download PDF

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KR20180100251A
KR20180100251A KR1020187024573A KR20187024573A KR20180100251A KR 20180100251 A KR20180100251 A KR 20180100251A KR 1020187024573 A KR1020187024573 A KR 1020187024573A KR 20187024573 A KR20187024573 A KR 20187024573A KR 20180100251 A KR20180100251 A KR 20180100251A
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cells
placental
stem cells
isolated
specific embodiment
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Korean (ko)
Inventor
스튜어트 애보트
제임스 더블유. 에딩거
알렉잔다르 프란키
블라디미르 얀코비치
알렉산드르 카플루노브스키
크리스텐 라바쪼
에릭 로우
비타오 리앙
로버트 제이. 하리리
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안트로제네시스 코포레이션
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
KR1020187024573A 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료 Ceased KR20180100251A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061424559P 2010-12-17 2010-12-17
US61/424,559 2010-12-17
PCT/US2011/065170 WO2012083024A1 (en) 2010-12-17 2011-12-15 Treatment of spinal cord injury and traumatic brain injury using placental stem cells

Related Parent Applications (1)

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KR1020137018583A Division KR20130128437A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

Related Child Applications (1)

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KR1020197021890A Division KR20190090882A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

Publications (1)

Publication Number Publication Date
KR20180100251A true KR20180100251A (ko) 2018-09-07

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KR1020187024573A Ceased KR20180100251A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020217026195A Ceased KR20210107144A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020237025647A Ceased KR20230116964A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌손상의 치료
KR1020197021890A Ceased KR20190090882A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020137018583A Ceased KR20130128437A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020207027962A Ceased KR20200116546A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020227023531A Ceased KR20220103812A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

Family Applications After (6)

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KR1020217026195A Ceased KR20210107144A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020237025647A Ceased KR20230116964A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌손상의 치료
KR1020197021890A Ceased KR20190090882A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020137018583A Ceased KR20130128437A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020207027962A Ceased KR20200116546A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020227023531A Ceased KR20220103812A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

Country Status (9)

Country Link
US (1) US20120156230A1 (https=)
EP (1) EP2651451A4 (https=)
JP (1) JP2014507390A (https=)
KR (7) KR20180100251A (https=)
CN (1) CN103501822A (https=)
AU (1) AU2011343739A1 (https=)
CA (1) CA2821818A1 (https=)
MX (1) MX2013006595A (https=)
WO (1) WO2012083024A1 (https=)

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ES2666503T3 (es) * 2012-05-16 2018-05-04 Becton, Dickinson And Company Características distintivas de superficie celular para aislar neuronas de cultivos celulares derivados de células madre pluripotentes
EP2863927A4 (en) * 2012-06-26 2015-12-02 Rusty Property Holdings Pty Ltd COMPOSITIONS AND METHODS FOR REDUCING THE FREQUENCY AND / OR INTENSITY OF THE CEPHALA
WO2014022427A1 (en) * 2012-08-02 2014-02-06 Bioaxone Biosciences Inc. Inhibition of rho and or rock and cell transplantation
US20160120909A1 (en) * 2013-05-10 2016-05-05 Cell-Innovations Ip Pty Ltd Compositions And Methods For The Treatment Of Tinnitus
US10058572B2 (en) * 2013-08-15 2018-08-28 The Regents Of The University Of California Placenta-derived multipotent stem cells
BR112016029624A2 (pt) 2014-06-18 2017-10-24 Csl Behring Gmbh terapia usando um inibidor do fator xii em um distúrbio neurotraumático
US10493105B2 (en) * 2014-09-11 2019-12-03 Taiwan Mitochondrion Applied Technology Co., Ltd Isolated adipose-derived mesenchymal stem cells treated with angelica extract or butylidenephthalide, and wherein the cells have an increased mitochondrial membrane potential and a decreased level of IL-8, and methods for treating parkinson's disease
GB201518263D0 (en) * 2015-10-15 2015-12-02 Oxford Bioelectronics Ltd Method
EP3423070B1 (en) * 2016-03-03 2022-05-04 Henry Ford Health System 3-d collagen scaffold-generated exosomes and uses thereof
EA201991371A1 (ru) * 2016-12-05 2019-12-30 Селулэрити, Инк. Лечение лимфедемы и связанных состояний с использованием плацентарных адгезивных клеток
US20200246386A1 (en) * 2017-04-24 2020-08-06 Pluristem Ltd. Methods and compositions for treating neurological disorders
US20180322956A1 (en) * 2017-05-05 2018-11-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Time Window-Based Platform for the Rapid Stratification of Blunt Trauma Patients into Distinct Outcome Cohorts
TW201910511A (zh) 2017-05-30 2019-03-16 美商維泰克斯製藥公司 C3融合蛋白以及其製備及使用方法
CN107227521B (zh) * 2017-08-09 2023-03-14 青岛金汇丰机械有限公司 一种五轴毛纺粗纱机
KR20190048894A (ko) 2017-10-31 2019-05-09 경상대학교산학협력단 Jnk 활성 억제제를 유효성분으로 포함하는 퇴행성 신경질환의 예방 또는 치료용 약학적 조성물
CN108413478A (zh) * 2018-02-11 2018-08-17 广东美的环境电器制造有限公司 一种控制方法、装置及计算机可读存储介质
KR102070403B1 (ko) 2019-09-06 2020-01-28 경상대학교 산학협력단 Jnk 활성 억제제를 유효성분으로 포함하는 외상성 뇌손상의 치료용 약학적 조성물
CN114561355B (zh) * 2022-01-23 2023-04-11 四川大学华西医院 一种脊髓瘢痕组织细胞急性快速分离方法
CN117274869B (zh) * 2023-09-25 2024-03-26 北方工业大学 一种基于形变场提取的细胞形变动态分类方法及系统

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US20080152629A1 (en) * 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
PL2471907T3 (pl) * 2005-12-29 2019-07-31 Celularity, Inc. Populacje komórek macierzystych łożyska
WO2008036374A2 (en) * 2006-09-21 2008-03-27 Medistem Laboratories, Inc. Allogeneic stem cell transplants in non-conditioned recipients
NZ612888A (en) * 2007-02-12 2015-02-27 Anthrogenesis Corp Treatment of inflammatory diseases using placental stem cells
US20090214484A1 (en) * 2008-02-22 2009-08-27 Nikolay Mironov Stem cell therapy for the treatment of central nervous system disorders
CA2734237C (en) * 2008-08-20 2019-07-02 Anthrogenesis Corporation Treatment of stroke using isolated placental cells
RU2015130665A (ru) * 2008-11-19 2018-12-24 Антродженезис Корпорейшн Амниотические адгезивные клетки

Also Published As

Publication number Publication date
EP2651451A4 (en) 2014-05-21
KR20230116964A (ko) 2023-08-04
KR20210107144A (ko) 2021-08-31
KR20190090882A (ko) 2019-08-02
KR20130128437A (ko) 2013-11-26
AU2011343739A1 (en) 2013-05-02
CN103501822A (zh) 2014-01-08
KR20220103812A (ko) 2022-07-22
EP2651451A1 (en) 2013-10-23
MX2013006595A (es) 2014-04-07
WO2012083024A1 (en) 2012-06-21
JP2014507390A (ja) 2014-03-27
WO2012083024A8 (en) 2013-08-01
KR20200116546A (ko) 2020-10-12
CA2821818A1 (en) 2012-06-21
US20120156230A1 (en) 2012-06-21

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