KR20180078529A - a functional antiseptic composite for wet wipes - Google Patents

Abstract

The present invention relates to an antiseptic composition for wet wipes, and more specifically, to an antiseptic composition for functional wet wipes comprised of disodium EDTA, sodium benzoate, polysorbate, citric acid, etc., which is harmless to the skin and has an enhanced antiseptic property. The present invention provides an antiseptic composition for functional wet wipes comprising disodium EDTA, sodium benzoate, polysorbate, citric acid, and purified water. Also, the present invention provides an antiseptic composition for functional wet wipes which is produced by further adding ethyl hexyl glycerin. Also, the present invention provides an antiseptic composition for functional wet wipes which is produced by further adding hexandiol. Also, the present invention provides an antiseptic composition for functional wet wipes which is produced by further adding antiseptic aid ingredients to markedly improve the product′s antiseptic property.

Description

A functional antiseptic composite for wet wipes < RTI ID = 0.0 >

The present invention relates to a preservative composition for a wet tissue, and more particularly to a preservative composition for a functional wet tissue having no harmfulness to skin and high antimicrobial activity including disodium dithiae, sodium benzoate, polysorbate, citric acid and the like.

In general, personal hygiene products such as cosmetics are easily contaminated by bacteria and fungi. To prevent such contamination, personal care products such as most cosmetics include preservatives that are essential to prevent common microbial contamination of all uses.

Unfortunately, most preservatives added to cosmetics are known to be toxic and can irritate or infect the skin.

In particular, the cosmetic industry uses a wide variety of preservative materials. One of the oldest and most commonly used preservatives in the cosmetics industry for a long time is esters of para-hydroxybenzoic acid, collectively known as parabens.

Because of the high toxicity of parabens, the cosmetics industry is simultaneously working on (i) a preservative system to replace the conventional paraben mixture, and (ii) various low toxicity combinations designed to enhance the efficacy of preservatives.

Thus, the need for non-toxic and non-irritating biocides that effectively destroy or inhibit the growth of microorganisms such as bacteria, yeast and fungi is still not met. The list of preservative materials produced in 2005 includes a limited number of preservative materials, leading to methyl- and propyl-paraben. An incomplete list of other preservative materials commonly used in the cosmetics industry is as follows: imidazolidinyl urea, phenoxyethanol, formaldehyde, quaternium 15, methylchloroisothiazolinone, methylisothiazolinone, and polyaminopropyl bar The synergistic combination of isoguanid (MTB), methyl isothiazolinone and chlorphenesin (MTC), methyl isothiazolinone and urethropropyl butyl carbamate (MTI), urethropropyl butyl Carbamate (IPBC), Rock conical ND, which is a combination of benzoic acid and dehydroacetic acid in phenoxyethanol, Rochonasal BSB, a combination of benzoic acid and sorbic acid in benzyl alcohol, Australian plum oil, Usninic acid, JM ActiCare / Water / sulfosuccinate gelatin suspension of titanium dioxide composite particles, polyaminopropyl bi-guanide, and the like.

Typical preservatives, particularly certain classes of preservatives, have been criticized over the past few years and some manufacturers have already chosen to re-formulate. The cosmetics industry knows that a significant number of consumers are reluctant to preserve. There is also a potential conflict between the need for non-polluting products and the need for zoological safety. Today, cosmetics can only use a limited number of preservatives (EPC Guideline 94/62 / EC), which are selected from the positive list, eg Volume VI of the Cosmetic Handbook, Volume VI, which also limits the maximum acceptable level and area of use.

In the case of wet tissues used as personal hygiene products, preservatives that act as preservatives used in cosmetics are used. Presently used preservatives are chloromethyl isothiazolinone and methyl isothiazolinone (Methyl Isothiazolinone) is used as a preservative. However, the preservative is excellent in buoyancy, but the problem due to skin irritation has arisen, and its use is limited in advanced countries such as the United States, Japan, and Europe.

Thus, in the face of safety evaluators who are concerned about the inclusion of preservatives even when mixed with common preservatives, in particular the consumer's rejection of some of them, and the levels of use and practices set forth in the Cosmetic Guidelines, There is still a need for innovative, safe and much more acceptable alternative methods.

In order to solve the above-mentioned problems, the present invention provides a preservative composition for skin hypo-allergenic wipes, which is disclosed in Patent Document 10-1431090 (hereinafter referred to as " antiseptic composition for skin hypo-allergenic wipes, A preservative composition for a wet tissue comprising any one of Cetylpyridinium chloride and Polyhexamethylene biguanide, Methhlparaben or Isopropyl methylphenol has been proposed.

The above-mentioned prior art is a cause of chemical burns such as skin damage, eczema and the like due to strong skin irritation of a preservative for wet tissue containing isothiazolinone compound used, and the present invention aims to provide a preservative that solves the above problem.

In addition, the prior art described above is still insufficient in prevention of chemical burns such as skin damage and eczema, and is insufficient in skin hypoallergenic, anti-fungal, anti-bacterial, etc. The present invention is characterized in that a preservative for a functional wet tissue Composition.

In order to solve the above problems and needs,

Disodium EDTA, sodium benzoate, polysorbate, citric acid, preservative compositions for functional wipes are provided. The disodium EDTA, disodium EDTA, sodium benzoate, polysorbate, citric acid and the like.

The present invention provides a preservative composition for a functional wet tissue comprising disodium EDTA, sodium benzoate, polysorbate, citric acid, and purified water.

The present invention also provides a preservative composition for a functional wet tissue prepared by further adding ethylhexyl glycerin.

The present invention also provides a preservative composition for a functional wet tissue prepared by further adding hexanediol.

Further, the present invention provides a preservative composition for a functional wet tissue in which antimicrobial auxiliary components are further added to significantly improve antimicrobial activity.

The preservative composition for a functional wet tissue according to the present invention has an effect that no chemical burns such as skin damage and eczema occur at all.

In addition, the preservative composition for a functional wet tissue according to the present invention exhibits remarkably high effect in skin hypoallergenic, anti-fungal, anti-bacterial,

In particular, the present invention is eco-friendly because it contains natural ingredients, thereby remarkably reducing irritation to the skin and exhibiting excellent effects in terms of antibacterial activity.

Hereinafter, the present invention will be described in detail.

The present invention provides a preservative composition for use in a personal hygiene product such as a wet tissue, which is excellent in preservative effect, has little skin irritation, and has excellent antibacterial and antibacterial properties.

The present invention provides a preservative composition for a functional wet tissue comprising Disodium EDTA, Sodium Benzoate, Polysorbate, and Citric.

The present invention also provides a preservative composition for functional wipes comprising Disodium EDTA, Sodium Benzoate, Polysorbate, Citric, and Purified Water.

Preferably, 100 parts by weight of disodium EDTA is added to 100 to 1000 parts by weight of sodium benzoate, 1 to 150 parts by weight of polysorbate, citric acid, 1 to 150 parts by weight of a preservative composition for a functional wet tissue.

Preferably, the disodium EDTA is added to 100 parts by weight of disodium EDTA, 100 to 1000 parts by weight of sodium benzoate, 1 to 150 parts by weight of polysorbate, ) 1 to 150 parts by weight of water and 3,000 to 30,000 parts by weight of purified water to prepare a preservative composition for a functional wet tissue.

The preservative composition for a functional wet tissue composed of the above-mentioned weight portion of the present invention has no skin irritation and does not cause problems of chemical burns such as skin damage and eczema.

In addition, the present invention exhibits significantly higher characteristics than other preservatives in antifungal and antibacterial properties.

Disodium EDTA is a component that prevents small amount of metal substances in cosmetics from being catalyzed to the skin. It is used to prevent discoloration. It is located at the rear side when entering into cosmetics, and a small amount .

The above-mentioned sodium benzoate performs the function of a corrosion inhibitor, a sterilizing preservative, and a flavoring agent.

The above-mentioned polysorbate is an additive used for uniformly dispersing a liquid or solid which is not well mixed with each other in a liquid. Emulsifiers and dispersants.

In particular, polysorbate 20 is a yellow to yellowish brown liquid with a slight peculiar smell and unpleasant but slightly bitter taste. Polysorbate 20 is a partial ester mixture of sorbitol condensed with ethylene oxide at approximately 20 M and lauric acid, a sorbitol anhydride, for 1 M of 1 or 2 anhydrides of sorbitol or sorbitol. It dissolves in water, ethanol, methanol, ethyl acetate, dioxane, but does not dissolve in petroleum ether. The o / w type emulsifier has an HLB value of 13.3. The daily allowable daily intake (ADI) of the FAO / WHO Expert Committee is 0.0 to 25.0 mg / kg. Used as an emulsifier and dispersant

Citric acid refers to tricarboxylic acid C3H4 (OH) (COOH) 3 with one OH group.

Tangerine, lemon and many other plants. It is also called citric acid. Citizen is the nickname of citron citron. Citric acid, an English name, is derived from citrus, a Greek word for citrus. Crystallization in water produces large columnar crystals with a single crystal number. When heated, it becomes an anhydride (anhydride), which has a melting point of 153 ° C. Higher temperatures result in aconitic acid at 175 ° C and at higher temperatures itaconic anhydride and citraconic acid anhydride and acetone dicarboxylic acid as disulfide products. It dissolves well in water and ethanol. When a microorganism is cultured using a saccharide as a substrate, citric acid accumulates in the culture liquid, which is referred to as citric acid fermentation. Various cultivation methods have been studied and now 90% of the total amount of citric acid produced in the world is produced by this fermentation process. Citric acid is usually obtained by fermentation at acidic (pH 2 ~ 3) at about 30 ℃ for 7 ~ 10 days. In addition, as a component of the TCA circuit, citric acid plays an important role in the metabolism of higher animals, and is known to promote calcium absorption in the body. Biologically it is used as a reagent for the analysis of metal ions in the citric acid circuit, and as a practical additive to soft drinks. Calcium ions are needed for blood coagulation. Citrate is used as a blood coagulation inhibitor because it captures calcium ions.

A technical feature of the present invention is to provide a preservative composition for a functional wet tissue, which is prepared by further adding ethylhexyl glycerin to the above composition.

The present invention provides a preservative composition for a functional wet tissue, which is obtained by further mixing 30 to 900 parts by weight of ethylhexyl glycerin based on 100 parts by weight of disodium EDTA.

The above-mentioned ethylhexyl glycerin of the present invention acts as a solvent for making skin vitality and dissolving other ingredients, and also enhances the antimicrobial power of preservatives, thereby reducing the amount of preservatives used.

The technical feature of the present invention also provides a preservative composition for a functional wet tissue prepared by further adding hexanediol to the above composition.

The present invention provides a preservative composition for a functional wet tissue comprising 100 to 1000 parts by weight of hexanediol based on 100 parts by weight of disodium EDTA.

The above-mentioned hexanediol of the present invention performs the function of antiseptic and antimicrobial properties, and has a characteristic of having excellent functions even in moisturizing, and has a characteristic of being excellent in compatibility with water (purified water), alcohol and the like.

A technical feature of the present invention is to provide a preservative composition for a functional wet tissue in which antimicrobial auxiliary components are added to the above composition to significantly improve antimicrobial activity.

The present invention provides a preservative composition for a functional wet tissue comprising 5 to 20 parts by weight of an antimicrobial auxiliary component based on 100 parts by weight of disodium EDTA.

The antimicrobial auxiliary component of the present invention refers to a composition prepared by using natural herbs and extracted with a mixture of Sanso, yellow pear, persimmon, ginseng, white pear, gosam, mandarin orange, white pear bloom, sake, and ginseng.

The antimicrobial auxiliary component is added to 100 parts by weight of the antimicrobial auxiliary component in an amount of 80 to 120 parts by weight, 80 to 120 parts by weight, 80 to 120 parts by weight, 80 to 120 parts by weight, 80-120 parts by weight, 80-120 parts by weight, , 80-120 parts by weight of white sugar, 80-120 parts by weight of white sugar, 80-120 parts by weight of sweet sugar, and 80-120 parts by weight of black sugar.

The method for extracting the antibacterial auxiliary component means that 100 to 10,000 parts by weight of water is mixed with 100 parts by weight of the raw material mixed by the above-mentioned weight, and the mixture is extracted by heating.

As a method for extracting the above-mentioned antimicrobial auxiliary components, 1,000 parts by weight of 80% [mass%] ethanol is added to 100 parts by weight of the raw material mixture, refluxed for 3 hours and the filtrate is concentrated under reduced pressure using a rotary evaporator Method.

When 1000 parts by weight of water is mixed with 100 parts by weight of the raw material and extracted, about 800 to 1000 parts by weight of the extract is obtained.

Allium hookeri of the present invention is a medicinal plant belonging to Alliaceae, and its roots and taste resemble ginseng, so that it has three flavors, or bitter taste, spicy taste and sweet taste,菜) is also called. Currently, it is cultivated and sold in Korea, and most of it is consumed for edible purposes. On the homepage of the Korea Food and Drug Administration, sulfur compounds as main ingredients are introduced as sulfur compounds. These sulfur compounds have anti-inflammation, antioxidant, As a component, it is said to be about six times as many as garlic.

According to the present invention, the whiteness of the whiteness is derived from the bark of the whitewood tree to the pharmacopeia, and it is also called the whitish bloom. It is a deciduous broad-leaved arboreous tree with a height of 10m. The shell has developed cork and the inner skin is yellow. Leaves are opposite to each other, with double leaf petiole, 5 ~ 13 petioles, egg-shaped lanceolate or long round. There are small sawtooth and soft hairs on the edge of the leaf, and there are some long hairs on the base of the middle vein. Yellow flowers bloom in May-June, which is a monotony of diatoms. The conical shape is a long circular shape, the male flower has 5 stamens, and the female flower has degenerated stamens. It has 5 chambers, style is short and stigma is divided into 5 branches. The fruit has a lot of flesh of 黄果 相 (果果 状), it has a hard core in the center, and when it is cooked in round shape, it has a black color. It is distributed in all regions except Jeju and Jeonnam regions in Korea. It is distributed in Japan, Manchuria, China, Amur, and Sochi, and grows in forests or mountain valleys.

The perennial herb of the present invention is a perennial plant of Saururus chinensis, whose leaves are alternate phyllotaxis, wide ovate heart shape and 3-8 cm long.

The fruit is seed vessel, and the seed is light brown. Use the plants before the flowering as a diuretic and insect repellent, and apply the leaves when they are bitten by boils and insects. In the private sector, it is used for swelling, pneumonia and hemorrhoids. In one room, plants are used for gonorrhea, enteritis, urinary tract infections, pneumonia and bronchitis. Leaves are similar to leaves of buckwheat and are called medicinal plants because they are medicinal plants. It is distributed in Korea (Ulleungdo, Anmyeondo, Geoje Island), Japan, China, Himalaya, Java.

The present invention is a flower bud of a L. japonica Thunb. Belonging to genus lonicera, or a flower which starts to bloom, in the Caprifoliaceae. China also uses the buds and flowers of L. japonica Thunb. As originals of gold eurows in Korea. In addition, there are also L. macranthoides, L. hypoglauca, (L. confusa), and L. fulvotomentosa.

The white paper of the present invention is a medicinal product made by drying the root of Angelica dahurica Bentham et Hooker or its variant (Korea). In China, only the prairie is used. In Japan, the prairie and the Angelica dahurica formosana (臺灣 当归) are used in Japan.

The gosam of the present invention is also referred to as a sperm tree of a staff, a rodent, a snakes, and a snake of a thief. It grows in a sunny grass. It is green with a height of 80 ~ 100cm, but it is black when it is young. The stem is straight, leaves are alternate, odd numbered compound leaf. Small leaves are 15 ~ 40, long oval or long ovate, 2 ~ 4cm long, 7 ~ 15mm butterfly. The petiole is long and the edge is flat.

In one room, dried roots are called roasted roasted roasted roasted roasted roasted roasted roasted ginseng. In the private sector, it is also used as an insecticide by dying stem or leaf. They are the same plants and have mountain peaks. They look very similar. They are distributed in Korea, Japan, China, and Siberia.

In the present invention, dried roots are preferably used, but leaves and stems may be used.

The buckwheat of the present invention means a seed of buckwheat, which is an annual herbaceous plant belonging to the genus Lepidoptera.

The seeds are made from buckwheat rice, which is cooked and cooked. It is a starchy crop, but it has a high protein content and contains vitamin B1 · B2 and nicotinic acid. Powder has become a raw material for making confectionery and cotton. In Korea, I ate mexican and cold noodles for a long time. It has a high fiber content and contains rutin, which is used as an antiparasitic or hypotensive agent. It is also grown for the purpose of producing this routine.

The vinegar in the present invention means the above-mentioned buckwheat seed and is used.

The white pine skin of the present invention refers to the root bark of the white pike (Dictamnus dasycarpus Turcz.) In Korea. In China, it was the same as our country, and in Japan, it was not treated as a process medicine.

It is also used for seawater, throat drying, and alternating swelling due to skin rash, skin eruption, eczema, rubella, itching, allergic dermatitis, nervous dermatitis and jaundice caused by acute hepatitis,

The antipyretic action and skin fungicide inhibitory action were reported by the pharmacological action of white blood.

The present invention means a bananas.

The bananas grow in the grass or the rice fields. The roots fall from the node with the vine hanging sideways. Leaves are alternate, leaves on roots are leaves with 3 small leaves, small leaves are egg-shaped or egg-shaped, 2 ~ 3.5cm long, 1 ~ 3cm wide. This shape has serrations on the edges of the leaves and long hairs on the back. The stipule is egg-shaped and the edge is flat.

The flower blooms from April to May in yellow and long flower stalks are emerging from the axil side, and one flower hangs at the end. Calyx is ovate, calyx is divided into 5 pieces and again divides into 3 shallows. The petals are wide ovate and 5 ~ 10mm long. Fruits are achene, ripened in June, round, rounded to 1cm in diameter and can be eaten. It is distributed in Korea, China, Japan, Malaysia and India.

The fruit of the present invention is mainly fruit, but leaves or stems may be used.

The ginseng of the present invention means ginseng, which is called ginseng (ginseng), ginseng (ginseng), ginseng (ginseng), ginseng (ginseng) and ginsams. . The name "Sansan" is white, and it is a name that is well known and adhered to in the sand. There are many white juices in the roots, and these people also called onions.

The ginseng replenishes the essence to soften the lungs, to cool the fever, to get rid of the feces and to dry it, dry cough, sputum, seawater and asthma. It is used for symptom of constipation which dry mouth is dry and throat is dry due to shortage of forgery.

The pharmacological effects of gadam work, antimicrobial action, hemolytic action, and cardiac action have been reported.

The technical feature of the present invention is to provide a preservative composition for a functional wet tissue, which is obtained by adding a detoxifying neutralizing component to the above-described composition to significantly reduce the toxicity of the skin.

The present invention provides a preservative composition for a functional wet tissue comprising 3 to 15 parts by weight of a decontamination neutralizing component based on 100 parts by weight of disodium EDTA.

The detoxification neutralizing component of the present invention can be extracted by mixing gold and green tea, licorice, wheat and vinegar with distilled water and heating.

Also, it means a composition obtained by mixing a mixture of gold, green tea, licorice, astringent and vinegar, using an alcohol extraction method.

The detoxification neutralizing component functions to detoxify or neutralize toxic components contained in the antimicrobial composition and to help the antibacterial composition to be coated on the filter portion.

The detoxifying neutralizing component is prepared by mixing 80-120 parts by weight of green tea, 80-120 parts by weight of licorice, 80-120 parts by weight of silkworm, and 80-120 parts by weight of vinegar with 300-1,000 parts by weight of distilled water in 100 parts by weight of gold, .

300 to 800 parts by weight of the detoxification neutralizing component obtained by heating and extracting by the above weight unit is extracted.

The gold mentioned above refers to a medicament made from roots of Scutellaria baicalensis GEORGE, a perennial herbaceous plant belonging to the family Lamiaceae.

The above-mentioned green tea means a tea for producing an ordinary green tea, and the stem, root, and leaf of green tea can be used.

The above licorice means normal licorice.

Licorice root is reddish brown, deeply penetrates into the ground, and the stem grows and grows about 1m straight. Also, the white hairs are dense and appear grayish white, and glandular dots are scattered. Leaves are alternate and odd numbered double leaf. Small leaves are 7 ~ 17 eggs, egg shaped and pointed end. The length of small leaf is 2 ~ 5cm, butterfly is l ~ 3cm and there are white feathers on both sides and there is no sawtooth.

In Japan, the root of the Achyranthes japonica Nakai or Achyranthes bidentata Blume is the Acridanthes bidentata Blume and the Achyranthes fauriei H. Lev . & Vaniot) is used. China recognizes only the Achyranthes bidentata Blume (牛 膝).

The above-mentioned bait is also called a strong peony. It grows in deep mountains. It is 40 ~ 50cm in height. The roots are thick and fleshy, and the bottom is covered with scaly leaves. Leaves are 3 ~ 4 slices and split 3 ~ 2 times. The small leaf is long oval or the egg is turned upside down. The edge is flat and has no hair.

The flowers bloom in June and are 4 ~ 5cm in diameter and run one at the end of the main stem. Calyx is ovate, 3, petals are inverted, 5 ~ 7. There are several operations and three or four ovaries. The fruit appears as a stigma and a red seed grows less red, and a mature black seed appears inside

The present invention provides a preservative composition for a functional wet tissue comprising the above composition.

<Examples>

1. Example

(1) A functional antiseptic composition was prepared by mixing the following components (this composition is referred to as Victory Bio 70).

Disodium iodide; EDTA, 1 N A, 1 g

Sodium benzoate; Purox S, 3g

Polysorbate 20: Tween 20, 0.3 g

Citric Acid, Citric Acid, 0.3 g

Ethylhexyl glycerin: Ethylhexylglycerin, 3 g

To prepare 7.6 g of a preservative composition (A) for a functional wet tissue.

(2) A functional antiseptic composition was prepared by mixing the following components (this composition is referred to as Victory Bio 71).

Disodium iodide; EDTA, 1 N A, 1 g

Sodium benzoate; Purox S, 3g

Polysorbate 20: Tween 20, 0.3 g

Citric Acid, Citric Acid, 0.3 g

Hexanediol: hexanediol, 4 g

To prepare 8.6 g of a preservative composition (B) for a functional wet tissue.

2. Experimental results

(1) The preservative compositions (A) and (B) of the functional wet tissue of the present invention prepared as described above were diluted into 1000 g of distilled water to prepare an aqueous solution. The water was then added to the wet tissue, (Escherichia coli) and Staphylococcus (Staphylococcus) were added to a trypticase soy agar plate culture medium at a concentration of 10 cfu / ml, and the cells were incubated with a phosphate buffer for 10 minutes. ml and incubated at 35 ± 1 ° C for 48 hours in an incubator.

The strains immediately after and 5 minutes after the injection of the strain were measured,

As a result of the above experiment, it can be seen that the present invention has no bacterial proliferation and thus has excellent antimicrobial activity.

(2) Also tested for antibacterial, bactericidal, skin irritation and moisturizing.

The skin irritation and moisturizing properties were evaluated in 35 adult men and women who were treated with the wet tissue (A) and (B) by diluting them with aqueous preservative composition (A) and (B) It was measured 10 days for 6 minutes of rubbing on the back of the hand and leg for 2 minutes per day.

Composition (A) Composition (B) Control group (C) Antimicrobial activity Great Great usually Sterilization Great Great usually Skin irritation none none has exist Moisturizing property Great Great usually

As shown in Table 1, it can be seen that the wipes using the compositions (A) and (B) of the present invention are excellent in antibacterial and bactericidal properties, have no irritation to the skin, and have a remarkably high moisture retention.

The present invention provides a preservative composition for a functional wet tissue having the above-described constitution and function.

The present invention is very useful in an industry for producing, manufacturing, selling, distributing and researching a composition relating to preservatives.

In particular, the present invention is very useful for an industry that produces, manufactures, sells, distributes and researches a preservative composition for a wet tissue.

Claims (4)

A preservative composition for a functional wet tissue comprising Disodium EDTA, Sodium Benzoate, Polysorbate, Citric Acid.
The method according to claim 1,
A preservative composition for a functional wet tissue prepared by further adding ethylhexyl glycerin.
The method according to claim 1,
A preservative composition for a functional wet tissue prepared by further adding hexanediol.
4. The method according to any one of claims 1 to 3,
A preservative composition for a functional wet tissue wherein antimicrobial auxiliary components are further added to improve antimicrobial activity.