KR20180055824A - 항 메소텔린 완전 인간 항체 및 메소텔린을 타겟팅하는 면역효과 세포 - Google Patents
항 메소텔린 완전 인간 항체 및 메소텔린을 타겟팅하는 면역효과 세포 Download PDFInfo
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- KR20180055824A KR20180055824A KR1020187007893A KR20187007893A KR20180055824A KR 20180055824 A KR20180055824 A KR 20180055824A KR 1020187007893 A KR1020187007893 A KR 1020187007893A KR 20187007893 A KR20187007893 A KR 20187007893A KR 20180055824 A KR20180055824 A KR 20180055824A
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510519214.4 | 2015-08-21 | ||
| CN201510519214 | 2015-08-21 | ||
| PCT/CN2016/096292 WO2017032293A1 (zh) | 2015-08-21 | 2016-08-22 | 抗间皮素全人抗体以及靶向间皮素的免疫效应细胞 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180055824A true KR20180055824A (ko) | 2018-05-25 |
Family
ID=58099641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187007893A Ceased KR20180055824A (ko) | 2015-08-21 | 2016-08-22 | 항 메소텔린 완전 인간 항체 및 메소텔린을 타겟팅하는 면역효과 세포 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10793641B2 (https=) |
| EP (1) | EP3339326A4 (https=) |
| JP (1) | JP6994456B2 (https=) |
| KR (1) | KR20180055824A (https=) |
| CN (1) | CN106467573B (https=) |
| AU (1) | AU2016312015A1 (https=) |
| BR (1) | BR112018003339A8 (https=) |
| CA (1) | CA2996060A1 (https=) |
| CL (1) | CL2018000457A1 (https=) |
| HK (1) | HK1251948A1 (https=) |
| IL (1) | IL257563A (https=) |
| NZ (1) | NZ740855A (https=) |
| RU (1) | RU2748281C2 (https=) |
| SG (1) | SG11201801351RA (https=) |
| WO (1) | WO2017032293A1 (https=) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022030730A1 (ko) * | 2020-08-04 | 2022-02-10 | 주식회사 셀렌진 | 메소텔린에 특이적으로 결합하는 항-메소텔린 키메릭 항원 수용체 |
| WO2023277361A1 (ko) * | 2021-06-30 | 2023-01-05 | (주)이노베이션바이오 | 메소텔린 특이적 항체 및 이의 용도 |
| US11795215B2 (en) | 2020-08-04 | 2023-10-24 | Cellengene Inc | Anti-mesothelin chimeric antigen receptor specifically binding to mesothelin |
| WO2024096592A1 (ko) * | 2022-11-02 | 2024-05-10 | 주식회사 셀렌진 | 메소텔린에 대한 친화도가 상승된 키메릭 항원 수용체 및 이의 용도 |
| WO2024101962A1 (ko) * | 2022-11-11 | 2024-05-16 | 주식회사 유씨아이테라퓨틱스 | 유전자 조작된 세포 및 이의 용도 |
| WO2025063790A1 (ko) * | 2023-09-20 | 2025-03-27 | 주식회사 유씨아이테라퓨틱스 | 항-메소텔린 항체 및 이의 용도 |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| KR102211837B1 (ko) | 2013-01-14 | 2021-02-03 | 젠코어 인코포레이티드 | 신규한 이형이량체 단백질 |
| US10858417B2 (en) | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
| US10259887B2 (en) | 2014-11-26 | 2019-04-16 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and tumor antigens |
| PE20171324A1 (es) | 2014-11-26 | 2017-09-11 | Xencor Inc | Anticuerpos heterodimericos que se unen a cd3 y a antigenos tumorales |
| EP3223907A2 (en) | 2014-11-26 | 2017-10-04 | Xencor, Inc. | Heterodimeric antibodies that bind cd3 and cd38 |
| CN109715663B (zh) | 2016-06-28 | 2022-11-25 | Xencor股份有限公司 | 结合生长抑素受体2的异源二聚抗体 |
| JP2020531041A (ja) | 2017-08-28 | 2020-11-05 | 上海易楽生物技術有限公司 | ポリペプチドとポリペプチドに結合される抗体 |
| CN107557336B (zh) * | 2017-09-15 | 2020-02-14 | 山东兴瑞生物科技有限公司 | 一种抗muc16安全型嵌合抗原受体修饰的免疫细胞及其应用 |
| CN107488636A (zh) * | 2017-09-30 | 2017-12-19 | 山东兴瑞生物科技有限公司 | 一种携带分子开关的抗her2嵌合抗原受体修饰的免疫细胞及其应用 |
| KR101966362B1 (ko) * | 2017-10-20 | 2019-04-05 | 주식회사 녹십자 | 항-msln 항체 및 이를 포함하는 암 치료용 약학적 조성물 |
| JP6339283B1 (ja) | 2017-10-31 | 2018-06-06 | 国立大学法人 岡山大学 | Dna、ポリペプチド、抗メソセリン抗体、腫瘍イメージング剤及び複合体 |
| JP2021502100A (ja) | 2017-11-08 | 2021-01-28 | ゼンコア インコーポレイテッド | 新規抗pd−1配列を用いた二重特異性および単一特異性抗体 |
| CN109971717B (zh) * | 2017-12-28 | 2023-06-20 | 上海细胞治疗研究院 | 共表达cd40抗体与间皮素特异性嵌合抗原受体的t细胞及其用途 |
| CN109971714B (zh) * | 2017-12-28 | 2023-06-20 | 上海细胞治疗研究院 | 自表达pd-1抗体并靶向间皮素的嵌合抗原受体修饰t细胞及其用途 |
| CN109608549B (zh) * | 2017-12-29 | 2022-02-18 | 郑州大学第一附属医院 | 基于人源间皮素抗体的嵌合抗原受体、慢病毒表达载体及其应用 |
| EP3747433A4 (en) | 2018-02-02 | 2021-12-22 | Cafa Therapeutics Limited | COMBINATION OF CELL IMMUNOTHERAPY |
| MX2020009272A (es) * | 2018-03-06 | 2021-01-08 | Univ Pennsylvania | Receptores de antígeno quimérico del antígeno de membrana específico de próstata y métodos de uso de los mismos. |
| JP2021523090A (ja) | 2018-03-09 | 2021-09-02 | 科済生物医薬(上海)有限公司Carsgen Therapeutics Co.,Ltd. | 腫瘍を治療するための方法および組成物 |
| MX2020010241A (es) | 2018-03-28 | 2020-10-16 | Cero Therapeutics Inc | Composiciones de inmunoterapia celular y usos de las mismas. |
| EP3774906A1 (en) * | 2018-03-28 | 2021-02-17 | Cero Therapeutics, Inc. | Chimeric tim4 receptors and uses thereof |
| CA3096052A1 (en) | 2018-04-04 | 2019-10-10 | Xencor, Inc. | Heterodimeric antibodies that bind fibroblast activation protein |
| US20220127570A1 (en) | 2018-05-03 | 2022-04-28 | Cafa Therapeutics Limited | Immune effector cell and use thereof |
| CA3100446A1 (en) | 2018-05-15 | 2019-11-21 | Carsgen Therapeutics Co., Ltd. | Genetically engineered cell and application thereof |
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- 2016-08-22 CN CN201610704504.0A patent/CN106467573B/zh active Active
- 2016-08-22 KR KR1020187007893A patent/KR20180055824A/ko not_active Ceased
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- 2016-08-22 CA CA2996060A patent/CA2996060A1/en not_active Abandoned
- 2016-08-22 NZ NZ740855A patent/NZ740855A/en not_active IP Right Cessation
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| WO2022030730A1 (ko) * | 2020-08-04 | 2022-02-10 | 주식회사 셀렌진 | 메소텔린에 특이적으로 결합하는 항-메소텔린 키메릭 항원 수용체 |
| US11795215B2 (en) | 2020-08-04 | 2023-10-24 | Cellengene Inc | Anti-mesothelin chimeric antigen receptor specifically binding to mesothelin |
| WO2023277361A1 (ko) * | 2021-06-30 | 2023-01-05 | (주)이노베이션바이오 | 메소텔린 특이적 항체 및 이의 용도 |
| WO2024096592A1 (ko) * | 2022-11-02 | 2024-05-10 | 주식회사 셀렌진 | 메소텔린에 대한 친화도가 상승된 키메릭 항원 수용체 및 이의 용도 |
| WO2024101962A1 (ko) * | 2022-11-11 | 2024-05-16 | 주식회사 유씨아이테라퓨틱스 | 유전자 조작된 세포 및 이의 용도 |
| WO2025063790A1 (ko) * | 2023-09-20 | 2025-03-27 | 주식회사 유씨아이테라퓨틱스 | 항-메소텔린 항체 및 이의 용도 |
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| NZ740855A (en) | 2022-04-29 |
| BR112018003339A2 (pt) | 2018-11-21 |
| CN106467573A (zh) | 2017-03-01 |
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| RU2748281C2 (ru) | 2021-05-21 |
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| US10793641B2 (en) | 2020-10-06 |
| RU2018107802A3 (https=) | 2019-09-23 |
| SG11201801351RA (en) | 2018-03-28 |
| BR112018003339A8 (pt) | 2022-10-18 |
| CL2018000457A1 (es) | 2018-08-24 |
| EP3339326A1 (en) | 2018-06-27 |
| EP3339326A4 (en) | 2019-01-09 |
| JP2018529327A (ja) | 2018-10-11 |
| IL257563A (en) | 2018-04-30 |
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