KR20180050750A - 이식에 사용하기 위한 중간엽 줄기 세포(msc)의 증식 방법 - Google Patents

이식에 사용하기 위한 중간엽 줄기 세포(msc)의 증식 방법 Download PDF

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KR20180050750A
KR20180050750A KR1020187011049A KR20187011049A KR20180050750A KR 20180050750 A KR20180050750 A KR 20180050750A KR 1020187011049 A KR1020187011049 A KR 1020187011049A KR 20187011049 A KR20187011049 A KR 20187011049A KR 20180050750 A KR20180050750 A KR 20180050750A
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cells
fasl
inducing agent
apoptosis inducing
mesenchymal stem
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Korean (ko)
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탈 알모그
샤이 야르코니
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셀렉트 바이오테라퓨틱스 리미티드
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/25Tumour necrosing factors [TNF]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • C12N2501/48Regulators of apoptosis

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  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020187011049A 2015-09-24 2016-09-22 이식에 사용하기 위한 중간엽 줄기 세포(msc)의 증식 방법 Withdrawn KR20180050750A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562222853P 2015-09-24 2015-09-24
US62/222,853 2015-09-24
PCT/IL2016/051053 WO2017051421A1 (en) 2015-09-24 2016-09-22 Methods for propagating mesenchymal stem cells (msc) for use in transplantation

Publications (1)

Publication Number Publication Date
KR20180050750A true KR20180050750A (ko) 2018-05-15

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KR1020187011049A Withdrawn KR20180050750A (ko) 2015-09-24 2016-09-22 이식에 사용하기 위한 중간엽 줄기 세포(msc)의 증식 방법

Country Status (10)

Country Link
US (1) US11578306B2 (https=)
EP (1) EP3353286A1 (https=)
JP (1) JP7011827B2 (https=)
KR (1) KR20180050750A (https=)
CN (1) CN108138142A (https=)
AU (1) AU2016327285A1 (https=)
CA (1) CA2999140A1 (https=)
IL (1) IL258267B (https=)
RU (1) RU2018112710A (https=)
WO (1) WO2017051421A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201604304D0 (en) * 2016-03-14 2016-04-27 Tigenix S A U Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease
CA3081768A1 (en) * 2017-11-06 2019-05-09 King's College London Therapeutic substances, their preparation and diagnostic procedure
AU2019264974A1 (en) * 2018-05-08 2020-10-29 Cellect Biotherapeutics Ltd. Methods for expanding adipose-derived stem cells
CN113943705B (zh) * 2021-11-01 2023-09-19 北京大学口腔医学院 一种凋亡微囊泡及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68218A (en) 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5851832A (en) 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5736396A (en) 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
EP0893493A3 (de) 1997-07-21 2002-12-04 Aventis Pharma Deutschland GmbH Genetisch veränderte Zellen und deren Verwendung in der Prophylaxe oder Therapie von Erkrankungen
CA2653881C (en) * 2006-05-31 2016-08-23 Styx Llc Methods of selecting stem cells and uses thereof
CN105530946A (zh) * 2013-09-11 2016-04-27 南加利福尼亚大学 具有高度表达的fas配体的干细胞组合物

Also Published As

Publication number Publication date
CA2999140A1 (en) 2017-03-30
EP3353286A1 (en) 2018-08-01
JP2018528782A (ja) 2018-10-04
WO2017051421A1 (en) 2017-03-30
AU2016327285A1 (en) 2018-04-12
JP7011827B2 (ja) 2022-02-10
IL258267A (en) 2018-05-31
RU2018112710A (ru) 2019-10-24
IL258267B (en) 2022-05-01
CN108138142A (zh) 2018-06-08
US20180340144A1 (en) 2018-11-29
US11578306B2 (en) 2023-02-14

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Patent event date: 20180419

Patent event code: PA01051R01D

Comment text: International Patent Application

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