KR20180039117A - 아릴-치환된 디히드로퀴놀리논, 그의 제조법 및 제약으로서의 그의 용도 - Google Patents
아릴-치환된 디히드로퀴놀리논, 그의 제조법 및 제약으로서의 그의 용도 Download PDFInfo
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- KR20180039117A KR20180039117A KR1020187006580A KR20187006580A KR20180039117A KR 20180039117 A KR20180039117 A KR 20180039117A KR 1020187006580 A KR1020187006580 A KR 1020187006580A KR 20187006580 A KR20187006580 A KR 20187006580A KR 20180039117 A KR20180039117 A KR 20180039117A
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- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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Applications Claiming Priority (5)
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| US201662356579P | 2016-06-30 | 2016-06-30 | |
| US62/356,579 | 2016-06-30 | ||
| PCT/CA2016/050943 WO2017024408A1 (en) | 2015-08-11 | 2016-08-11 | Aryl-substituted dihydroquinolinones, their preparation and their use as pharmaceuticals |
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| KR20180039117A true KR20180039117A (ko) | 2018-04-17 |
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| JP (1) | JP2018527340A (https=) |
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| CN (1) | CN108290856A (https=) |
| AU (1) | AU2016305513A1 (https=) |
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| IL (1) | IL257347A (https=) |
| MX (1) | MX2018001751A (https=) |
| WO (1) | WO2017024408A1 (https=) |
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| WO2020093162A1 (en) * | 2018-11-07 | 2020-05-14 | Neomed Institute | Treatment of bet inhibitor-resistant cancers and other diseases responsive to dual bet and cbp/ep300 inhibition therapy |
| CN113631535B (zh) * | 2019-03-11 | 2024-04-12 | 协同医药发展有限公司 | 治疗铁死亡相关紊乱的杂芳基和双杂环芳基衍生物 |
| CN112239456B (zh) * | 2020-06-09 | 2021-09-07 | 浙江理工大学 | 一种取代2，3-二氢喹诺酮化合物的制备方法 |
| CN114276333B (zh) * | 2020-09-28 | 2023-05-09 | 中国科学院上海药物研究所 | 二氢喹喔啉类溴结构域二价抑制剂 |
| EP4703364A1 (en) * | 2023-04-23 | 2026-03-04 | Horizon Omics Biotech Limited | Quinolone analog and use thereof |
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2016
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2018
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2019
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| EP3334717A1 (en) | 2018-06-20 |
| CA2994472A1 (en) | 2017-02-16 |
| JP2018527340A (ja) | 2018-09-20 |
| EP3334717B1 (en) | 2020-07-01 |
| US10501438B2 (en) | 2019-12-10 |
| MX2018001751A (es) | 2018-08-01 |
| HK1256753A1 (zh) | 2019-10-04 |
| AU2016305513A1 (en) | 2018-03-08 |
| IL257347A (en) | 2018-03-29 |
| WO2017024408A1 (en) | 2017-02-16 |
| US20200299262A1 (en) | 2020-09-24 |
| CN108290856A (zh) | 2018-07-17 |
| US20180230130A1 (en) | 2018-08-16 |
| EP3334717A4 (en) | 2019-02-13 |
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