KR20180030287A - Cosmetic composition comprising nanoemulsion containing horse oil or camellia oil - Google Patents

Abstract

The present invention relates to a cosmetic composition, and more particularly to a cosmetic composition including a nanoemulsion containing horse oil or camellia oil, which includes the nanoemulsion including 5 to 20 parts by weight of camellia oil or horse oil, 0.5 to 10 parts by weight of an amphiphilic block polymer, 0.5 to 2 parts by weight of lecithin and 60 to 85 parts by weight of water and has a high skin absorption rate without changing a particle size due to dispersion stability.

Description

[0001] The present invention relates to a cosmetic composition comprising nanoemulsion containing horse oil or camellia oil,

The present invention relates to a cosmetic composition, and more particularly, to a cosmetic composition comprising a nanoemulsion containing 5 to 20 parts by weight of camellia oil or talc, 0.5 to 10 parts by weight of an amphiphilic block polymer, 0.5 to 2 parts by weight of lecithin and 60 to 85 parts by weight of water And a nanoemulsion containing horse oil or camellia oil which does not change the particle size due to dispersion stability and is excellent in skin absorption rate.

Mayu is a fat ingredient extracted from the fatty tissue of horses. It has moisturizing, skin protection, promoting cell regeneration, ultraviolet screening and antibacterial effects. Camellia oil obtained from camellia seeds also calms skin troubles and compensates for insufficient skin lipids. Giving contains ingredients. For the above reasons, various forms of cosmetics containing skin or camellia oil or external preparations for skin have been developed. However, it is not easy to penetrate skin with camellia yunuma oil alone. Therefore, a method of using camellia yamma-yu as an emulsifying agent in a cosmetic composition can be considered, as in the following Patent Document, in which an emulsion is used for a cosmetic composition.

<Patent Literature>

Open Patent No. 10-2007-0043449 (published on Apr. 25, 2007) "Nano emulsion skin anti-aging cosmetic composition"

However, in the case of producing an emulsion containing Mayu or camellia oil by the conventional method of manufacturing a nano emulsion, nano-sized droplets collide more and more constantly, so that droplet aggregation or coalescence occurs during the collision, There is a problem that the percutaneous absorption rate of the cosmetic raw material is deteriorated.

The present invention has been made to solve the above problems,

It is an object of the present invention to provide a cosmetic composition comprising nanoemulsion containing horse oil or camellia oil which does not change particle size due to dispersion stability and has excellent skin absorption rate.

In order to achieve the above object, the present invention is implemented by the following embodiments.

According to one embodiment of the present invention, the cosmetic composition according to the present invention comprises a nano emulsion containing 5 to 20 parts by weight of camellia oil or talc, 0.5 to 10 parts by weight of an amphiphilic block polymer, and 60 to 85 parts by weight of water .

According to another embodiment of the present invention, in the cosmetic composition according to the present invention, the nanoemulsion further comprises 0.5 to 2 parts by weight of lecithin.

According to another embodiment of the present invention, a method for producing a cosmetic composition according to the present invention comprises dissolving an amphiphilic block polymer and lecithin in a solvent at a temperature of 30 to 50 ° C, adding liquid milky oil or camellia oil to prepare a mixture Preparing an emulsion by adding water slowly while stirring the mixed solution to produce an emulsion by phase transformation; removing the solvent from the emulsion; And a size adjusting step of reducing the particle size to a nano size range.

According to another embodiment of the present invention, in the method for preparing a cosmetic composition according to the present invention, at least one selected from the group consisting of ethanol, tetrahydrofuran and methylene chloride is used as the solvent in the step of preparing the mixture, In the emulsion preparation step, purified water is added at a rate of 400 to 600 μl / min while stirring the mixed solution at 300 to 400 rpm. In the solvent removal step, the solvent present in the emulsion is removed by distillation under reduced pressure, Characterized in that the emulsion from which the solvent has been removed is treated with an ultrasonic disperser or a high-pressure emulsifier.

According to another embodiment of the present invention, a method for preparing a cosmetic composition according to the present invention further comprises a step of obtaining a liquid phase, wherein the step of purifying the muscle comprises pulverizing horse meat, Extracting the crude fat by heating and then filtering the filtrate and the residue, pressing the separated residue to obtain a pressurized liquid, and distilling the filtrate and the pressurized liquid under reduced pressure to extract the crude fat; A sonic wave treatment step of ultrasonic wave treatment, a chip heating step in which warm water is put into a persimmon skin chip to warm it, a crude fat filter step of filtering the crude fat obtained in the ultrasonic wave processing step through a warmed persimmon chip, After the step, the water layer and the fat layer were separated and the separated fat layer was allowed to stand at room temperature for a certain period of time, Characterized in that it comprises a separation step of separating Mayu.

According to another embodiment of the present invention, in the method for producing a cosmetic composition according to the present invention, the peel chip is obtained by hot-air drying the skin of an immature bean and its persimmon harvested in August and pulverizing the same using a pulverizer .

According to the present invention, the following effects can be obtained by this embodiment.

The present invention has an effect that the particle size is not changed due to the dispersion stability and the skin absorption rate is excellent.

1 is an electron transmission microscope image of a nanoemulsion according to an embodiment of the present invention.
Figure 2 is a diagram illustrating the particle size of the nanoemulsion according to one embodiment of the present invention.
3 is a graph showing changes in particle size after repeated freezing and thawing of a nanoemulsion according to an embodiment of the present invention.
4 is a graph illustrating the skin absorption rate of the nanoemulsion according to an embodiment of the present invention.

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, a cosmetic composition comprising a nanoemulsion containing horse oil or camellia oil according to the present invention will be described in detail with reference to the accompanying drawings. Unless defined otherwise, all terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs and, if conflict with the meaning of the terms used herein, It follows the definition used in the specification. Further, the detailed description of known functions and configurations that may unnecessarily obscure the subject matter of the present invention will be omitted. Throughout the specification, when an element is referred to as "including " an element, it is understood that the element may include other elements as well, without departing from the other elements unless specifically stated otherwise.

The cosmetic composition according to one embodiment of the present invention comprises nanoemulsion containing horse oil or camellia oil. The nanoemulsion is an oil-in-water (O / W) emulsion in the nano size range, preferably having a particle size of 50 to 500 nm. The nanoemulsion comprises 5 to 20 parts by weight of camellia oil or talc, 0.5 to 10 parts by weight of an amphiphilic block polymer, and 60 to 85 parts by weight of water. The nanoemulsion according to another embodiment may further comprise 0.5 to 2 parts by weight of lecithin. The above-mentioned camphor oil is extracted from camellia seeds, and Mayu oil is extracted from horse chestnut. The above-mentioned camellia oil or hemp oil may be used in a commercial product, and may be directly extracted and used by various methods such as known methods. As the amphiphilic block polymer, various known amphiphilic block polymers may be used, but preferably PEO-b-PCL can be used. The lecithin is a kind of phospholipids. The lecithin is produced by extracting from soybean or egg or by further purifying it. The content of phosphatidylcholine may be 30 to 95% by weight, preferably the content of phosphatidylcholine is 70% have. In the present invention, it is preferable that the nanoemulsion is contained in an amount of 0.001 to 30.0% by weight, preferably 0.01 to 10.0% by weight, based on the total weight of the cosmetic composition.

The cosmetic composition of the present invention may further comprise a composition selected from the group consisting of water-soluble vitamins, oiliness vitamins, polymer peptides, polymeric polysaccharides, sphingolipids and seaweed extracts.

As the water-soluble vitamin, any of vitamin B1, vitamin B2, vitamin B6, pyridoxine, pyridoxine hydrochloride, vitamin B12, pantothenic acid, nicotinic acid, nicotinic acid amide, folic acid, vitamin C and vitamin H can be used, And salts thereof (thiamine hydrochloride, sodium ascorbate, etc.) or derivatives (sodium ascorbic acid-2-phosphate, magnesium ascorbic acid-2-phosphate etc.) can also be used as water-soluble vitamins . The water-soluble vitamin can be obtained by a conventional method such as a microorganism conversion method, a purification method from a culture of a microorganism, an enzymatic method, or a chemical synthesis method.

As the above-mentioned useful vitamins, any vitamins A, carotene, vitamin D2, vitamin D3, vitamin E (d1-alpha tocopherol, d-alpha tocopherol, d-alpha tocopherol) , And derivatives thereof (such as palmitic acid ascorbin, stearic acid ascorbic acid, dipalmitic acid ascorbic acid, dl-alpha tocopheryl acetate, dl-alpha tocopherol nicotinic acid vitamin E, DL-pantothenyl alcohol, D-pantothenyl alcohol, Ethyl ether, etc.) and the like are also included in the usable vitamins used in the present invention. The usable vitamin can be obtained by a conventional method such as a microorganism conversion method, a purification method from a culture of a microorganism, an enzyme or a chemical synthesis method.

The polymeric peptide may be any compound as long as it can be compounded in a cosmetic, and preferably collagen, hydrolyzed collagen, gelatin, elastin, hydrolyzed elastin, keratin and the like. The polymeric peptide can be obtained by a conventional method such as purification from a culture broth of a microorganism, an enzymatic method, or a chemical synthesis method, or purified from natural products such as ducks such as pigs and cows and silk fiber of silkworms .

The polymeric polysaccharide may be any compound as long as it can be compounded in cosmetics, and examples thereof include hydroxyethylcellulose, xanthan gum, sodium hyaluronate, chondroitin sulfate or a salt thereof (sodium salt, etc.). For example, chondroitin sulfate or a salt thereof can be usually purified from mammals or fish.

The sphingogly lipid may be any as long as it can be compounded in cosmetics, and preferable examples thereof include ceramides, phytosphingosine and sphingoglycolipids. The sphingogly lipids can be purified from ordinary mammals, fish, shellfish, yeast or plants by a conventional method or can be obtained by chemical synthesis.

The seaweed extract may be any of those which can be compounded in cosmetics, but preferably include algae extract, red tiger extract, green algae extract and the like, and furthermore, coloring guanine, arginic acid, sodium alginate , Potassium alginate, and the like are also included in the seaweed extract used in the present invention. The seaweed extract can be obtained from seaweed by a conventional method.

The cosmetic composition of the present invention may contain other ingredients usually added to the cosmetic composition. For example, it is possible to use various additives such as a preservative, a moisturizer, an emollient, a surfactant, an organic and inorganic pigment, an organic powder, an ultraviolet absorber, an antiseptic, a bactericide, an antioxidant, a plant extract, a pH adjuster, Cold agents, antiperspirants, purified water, and the like.

Examples of the above-mentioned fat-soluble ingredients include ester-based fats, hydrocarbon-based fats, silicon-based fats, fluorine-based fats, animal fats and plant fats and the like. Examples of the ester-based oil include glyceryl tri-2-ethylhexanoate, cetyl 2-ethylhexanoate, isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl stearate, octyl palmitate, isostearyl isostearate, But are not limited to, ethylbutyl, butylbutyl, ethylbutylbutyl, butylbutyl, isobutylbutyl, isobutylbutyl, isobutylisobutyl, isobutylisobutyl, isobutylisobutyl, Trimethylol propane, triisostearic acid trimethylol propane, tetra-2-ethylhexanoic acid pentaerythritol tri (2-ethylhexanoic acid) But are not limited to, tallow, caprylic estersyl, decyl laurate, hexyl laurate, decyl myristate, myristyl myristate, myristine sasyl, stearyl stearate, decyl oleate, Examples of the isocyanates include isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, isophorone diisostearate, Ethylhexanoate, stearyl 2-ethylhexanoate, hexyl isostearate, ethylene glycol dioctanoate, ethylene glycol dioleate, propylene glycol dicaprate, di (capryl, capric acid) propylene glycol , Propylene glycol dicaprylylate, dicapric acid neopentyl glycol, dioctanoic acid neopentyl glycol, tricarboxylic acid glyceryl, triunsaturated acid glyceryl, triisopalmitic acid glyceryl, triisostearic acid glyceryl, neopentanoic acid octyl Dodecylsuccinic acid, octadecanoic acid, octadecanoic acid, octadecanoic acid, octadecanoic acid, octadecanoic acid, octadecanoic acid, Polyglycerin isostearic acid ester, triisocetyl citrate, triisoalkyl citrate, triisooctyl citrate, lauryl lactate, myristyl lactate, cetyl lactate, octyldecyl lactate, octyldecyl lactate, octyldecyl isostearate, polyglycerin oleic acid ester, But are not limited to, triethyl citrate, acetyl triethyl citrate, acetyl tributyl citrate, trioctyl citrate, diisostearyl malate, 2-ethylhexyl hydroxystearate, di-2-ethylhexyl succinate, diisobutyl adipate, Propyl stearate, propyl stearate, propyl stearate, stearyl stearate, stearyl stearate, propyl stearate, stearyl stearate, Stearyl hydroxystearate, stearyl 12-stearoyl hydroxystearate, 12-stearoyl hydroxystearic acid, Allo one hydroxy stearic acid and the like esters such as cetearyl source. Examples of the hydrocarbonaceous oil include hydrocarbons such as squalene, liquid paraffin, alpha-olefin oligomer, isoparaffin, ceresin, paraffin, floating isoparaffin, polybutene, microcrystalline wax and vaseline. Examples of the silicone-based oil include polymethyl silicone, methylphenyl silicone, methyl cyclopolysiloxane, octamethyl polysiloxane, decamethyl polysiloxane, dodecamethyl cyclosiloxane, dimethyl siloxane methyl cetyloxysiloxane copolymer, dimethyl siloxane methyl stearoxysiloxane copolymer, Alkyl-modified silicone oil, and amino-modified silicone oil. Examples of the fluorine-based oil include perfluoropolyether and the like. Examples of the animal or plant oil include avocado oil, almond oil, olive oil, sesame oil, rice bran oil, new flower oil, soybean oil, corn oil, rape oil, apricot kernel oil, palm kernel oil, palm oil, castor oil, The present invention relates to a process for producing a starch-containing starch, which is selected from the group consisting of seed oil, cottonseed oil, palm oil, palm oil, cucumber nut oil, wheat germ oil, rice germ oil, Animal or vegetable fats such as oil, can-pick wax, carnauba wax, liquid lanolin, and hardened castor oil.

Examples of the moisturizing agent include water-soluble low-molecular moisturizing agents, oil-soluble molecular moisturizing agents, water-soluble polymers, and oil-soluble polymers. Examples of the water-soluble low molecular weight moisturizing agent include serine, glutamine, sorbitol, mannitol, sodium pyrrolidone-carboxylate, glycerin, propylene glycol, 1,3-butylene glycol, ethylene glycol, polyethylene glycol B Propylene glycol (polymerization degree n = 2 or more), polyglycerin B (polymerization degree n = 2 or more), lactic acid, lactic acid salt and the like. Examples of the lipid-soluble low-molecular moisturizing agent include cholesterol, cholesterol ester and the like. Examples of the water-soluble polymer include carboxyvinyl polymer, polyaspartic acid salt, tragacanth, xanthan gum, methylcellulose, hydroxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, water-soluble chitin, chitosan, dextrin, . Examples of the oil-soluble polymer include polyvinylpyrrolidone / eicosene copolymer, polyvinylpyrrolidone / hexadecene copolymer, nitrocellulose, dextrin fatty acid ester, and polymer silicone.

Examples of the molient agent include long chain acyl glutamic acid cholesteryl ester, hydroxystearic acid cholesteryl, 12-hydroxystearic acid, stearic acid, rosin acid and lanolin fatty acid cholesteryl ester.

Examples of the surfactant include nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants. Examples of the nonionic surfactant include self emulsifying monostearic acid glycerin, propylene glycol fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester, POE (polyoxyethylene), sorbitan fatty acid ester, POE sorbit fatty acid ester POE glycerin fatty acid ester, POE alkyl ether, POE fatty acid ester, POE hardened castor oil, POE castor oil, POEPOP (polyoxyethylene polyoxypropylene) copolymer, POEPOP alkyl ether, polyether modified silicone, lauric acid alkanolamide , Alkylamine oxides, hydrogenated soybean phospholipids, and the like. Examples of the anionic surfactant include fatty acid soap, alpha-acylsulfonate, alkylsulfonate, alkylallylsulfonate, alkylnaphthalenesulfonate, alkylsulfate, POE alkyl ether sulfate, alkylamide sulfate, alkyl phosphate, POE alkyl ginseng salt, alkyl Amide phosphate, alkyloyl taurine salt, N-acyl amino acid salt, POE alkyl ether carboxylate, alkylsulfosuccinate, sodium alkylsulfoacetate, acylated hydrolyzed collagen peptide salt, perfluoroalkyl phosphate ester and the like . Examples of the cationic surfactant include alkyl trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, stearyl trimethyl ammonium bromide, cetostearyl trimethyl ammonium chloride, distearyl dimethyl ammonium chloride, stearyl dimethyl benzyl ammonium chloride, behenyl trimethyl ammonium bromide, Benzalkonium chloride, diethylaminoethylamide stearate, dimethylaminopropylamide stearate, quaternary ammonium salts of lanolin derivatives, and the like. Examples of the amphoteric surfactant include carboxybetaine, amidebetaine, sulfobetaine, hydroxysulfobetaine, amidosulfobetaine, phosphobetaine, aminocarboxylate, imidazoline derivative, amideamine, etc. , And the like.

Examples of the organic and inorganic pigments include silicic acid, anhydrous silicic acid, magnesium silicate, talc, sericite, mica, kaolin, spinach, clay, bentonite, titanium coated mica, bismuth oxychloride, zirconium oxide, magnesium oxide, Inorganic pigments such as aluminum, calcium sulfate, barium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, iron oxide, chromium oxide, chromium oxide, chromium oxide, But are not limited to, polyamide, polyester, polypropylene, polystyrene, polyurethane, vinyl resin, urea resin, phenol resin, fluororesin, silicon resin, acrylic resin, melamine resin, epoxy resin, polycarbonate resin, Silk powder, cellulose, CI Pigment Yellow, CI Pigment Orange, and composite pigments of inorganic pigments and organic pigments thereof.

Examples of the organic powder include metal soaps such as calcium stearate; Metal salts of alkyl phosphates such as sodium zinc cetylate, zinc laurylate and calcium lauryl laurate; Acylamino acid polyvalent metal salts such as N-lauroyl-beta-alanine calcium, N-lauroyl-beta-alanine zinc and N-lauroylglycine calcium; Amidosulfonic acid multivalent metal salts such as N-lauroyl-taurine calcium and N-palmitoyl-taurine calcium; Such as N-epsilon-lauroyl-L-lysine, N-epsilon-palmitoylidene, N-alpha-paratyylnitine, N-alpha-lauroyl arginine, Acyl basic amino acids; N-acylpolypeptides such as N-lauroylglycylglycine; Alpha-amino fatty acids such as alpha-aminocaprylic acid, alpha-aminoaurauric acid, and the like; Polyethylene, polypropylene, nylon, polymethylmethacrylate, polystyrene, divinylbenzene-styrene copolymer, ethylene tetrafluoride, and the like.

Examples of the ultraviolet absorber include ultraviolet absorbers such as p-aminobenzoic acid, ethyl p-aminobenzoate, amyl paranobenzoate, octyl p-aminobenzoate, ethylene glycol salicylate, phenyl salicylate, benzyl salicylate, benzyl salicylate, butylphenyl salicylate, homomenthyl salicylate, Benzyl, 2-ethoxyethyl methoxycinnamate, octyl methoxycinnamate, mono-2-ethylhexane glyceryl dipyrromethoxycinnamate, isopropyl methoxycinnamate, diisopropyl-diisopropyl cinnamate ester mixture, Dihydroxymethoxybenzophenone sulfonic acid, dihydroxybenzophenone sulfonic acid, dihydroxybenzophenone sulfonic acid and its salt, dihydroxymethoxybenzophenone, sodium dihydroxymethoxybenzophenone disulfonate, dihydroxybenzo Phenanone, tetrahydroxybenzophenone, 4-tert-butyl-4'-methoxydibenzoylmethane, 2,4,6-trianylino-p- (carbo-2'-ethylhexyl- 1,3,5-triazine, 2- (2- And the like can be de-hydroxy-5-methylphenyl) benzotriazole.

Examples of the bactericide include antibiotics such as hinokitiol, trichloroacid, trichlorohydroxydiphenyl ether, crohexidine gluconate, phenoxyethanol, resorcin, isopropylmethylphenol, azulene, salicylic acid, No. 301, mononitro and eicoll sodium, undecylenic acid, and the like.

Examples of the antioxidant include butylhydroxyanisole, gallic acid propyl, and eicosorbic acid.

Examples of the pH adjuster include citric acid, sodium citrate, malic acid, sodium malate, fumaric acid, sodium fumarate, succinic acid, sodium succinate, sodium hydroxide, sodium monohydrogenphosphate and the like.

Examples of the alcohol include higher alcohols such as cetyl alcohol.

In addition, any of the above components may be blended within the range not impairing the object and effect of the present invention, but is preferably 0.01 to 5% by weight based on the total weight, More preferably 0.01 to 3% by weight.

The cosmetic composition of the present invention may take the form of a solution, an emulsion, a viscous mixture or the like.

The ingredients contained in the cosmetic composition of the present invention may contain, as an active ingredient, the ingredients conventionally used in cosmetic compositions in addition to the above-mentioned compounds, for example, conventional additives such as stabilizers, solubilizers, vitamins, And a carrier.

The cosmetic composition of the present invention can be prepared in any formulations conventionally produced in the art, and examples thereof include emulsions, creams, foundations, lotions, essences, and hair cosmetic compositions. Specifically, the cosmetic composition of the present invention can be used as a skin lotion, a skin softener, a moisturizing lotion, a nutritional lotion, a massage cream, a nutrition cream, a hand cream, a moisturizing cream, an essence, a pack, a soap, a lotion, a milk lotion, Cleansing foams, body cleansers, astringents, and spray formulations. When the formulation of the present invention is a paste, cream or gel, animal fiber, plant fiber, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier component . When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In the case of a spray, in particular, / Propane or dimethyl ether. In the case of the solution or emulsion of the present invention, a solvent, a solvent or an emulsifier is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, , 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid esters. When the formulation of the present invention is a suspension, a carrier such as water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used. When the formulation of the present invention is an interfacial active agent-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, linolenic derivatives or ethoxylated glycerol fatty acid esters.

According to another embodiment of the present invention, there is provided a method for preparing a cosmetic composition comprising a nail emulsion containing a horse oil or a camellia oil, comprising dissolving an amphiphilic block polymer (and lecithin) in a solvent at a temperature of 30 to 50 캜, A step of preparing an emulsion by adding water slowly while stirring the mixed solution to produce an emulsion by phase transformation; a solvent removing step of removing the solvent from the emulsion; and a step of removing the solvent from the emulsion And a size adjustment step of reducing the particle size of the emulsion by applying an external force to a range of nano size.

The step of preparing the mixed solution is a step of dissolving the amphiphilic block polymer (and lecithin) in a solvent at a temperature of 30 to 50 DEG C and adding a liquid casein or camellia oil to prepare a mixed solution. Examples of the solvent include ethanol, tetrahydrofuran, Chloride and the like can be used.

The emulsion preparation step is a step of slowly adding water while stirring the mixed solution to prepare an emulsion through phase transformation. For example, purified water is added at a rate of 400 to 600 μl / min while stirring the mixed solution at 300 to 400 rpm .

The solvent removal step is a step of removing the solvent from the emulsion, for example, by distillation under reduced pressure to remove the solvent present in the emulsion.

The size adjustment step is performed by applying an external force to the solvent-removed emulsion to reduce the particle size of the emulsion to a range of nano-size, for example, by treating the solvent-removed emulsion using an ultrasonic disperser or a high-pressure emulsifier.

The method of manufacturing the cosmetic composition may further include a step of obtaining a liquid horse oil. In the step of horse oil purification, horse meat is ground, the water is mixed and heated, and then filtered to remove the filtrate and the residue A crude fat extracting step of extracting crude fat by vacuum distillation of the filtrate and the pressurized liquid to obtain a pressurized liquid by squeezing the separated and separated residues, an ultrasonic wave processing step of ultrasonic wave processing of the crude fat, And a heating step of heating the heated fat in the cooking chamber to warm the cooked fat by passing the heated fat through the warmed peel chips obtained in the ultrasonic wave processing step to remove the water layer and the fat layer after the crude fat filtering step, For a predetermined period of time at room temperature, and separating the liquid into a liquid state liquid and a solid state liquid state. In the step of refining the muscle, the crude lipid obtained by the first purification is passed through the peel chip, so that the liquid lipid can be separated from the liquid lipid layer and the solid lipid layer. Thus, the liquid lipid lipid can be easily obtained without any special operation. Is liquefied and is passed through the peel chip, so that the ultrasonic treatment can be performed in the process of boiling to increase the gain of the liquid phase. The peel chips were formed by pulverizing the peel husks to a size of about 2 × 2 cm using a pulverizer, and inserted into a cylinder-shaped container formed by mesh netting at the lower side and the upper side. The perch peel chips were able to increase the milk yield in the liquid state when prepared using a less ripe root feel than the ripe persimmon.

Hereinafter, the present invention will be described in more detail with reference to Examples. However, these are only for the purpose of illustrating the present invention in more detail, and the scope of the present invention is not limited thereto.

&Lt; Example 1 > Production of nanoemulsion containing camellia oil or horse oil

(1) Nanoemulsion Samples 1 to 7 having component ratios (unit weight%) shown in the following Table 1 were prepared.

(2) More specifically, the amphiphilic block polymer PEO-b-PCL (poly ( ethylene oxide) - b -poly (ε-caprolactone), PCL / PEO = 1.07 / 1, molecular weight = 7.3kDa, Polydispersity index = 1.37) And lecithin (Lipoid S75-3) were dissolved in tetrahydrofuran (THF), and then added with camellia oil (or horse oil) and dissolved at a temperature of 40 ° C to prepare a mixed solution (in the case of sample 7, lecithin was not used ).

(3) Purified water was added at a rate of 500 / / min while stirring the mixture at 330 rpm to prepare an emulsion. The prepared emulsion was distilled under reduced pressure to remove THF, and the emulsion with the solvent removed was dispersed in an ultrasonic disperser (VCX130, Sonic & Materials Inc., USA) for 5 minutes.

PEO-b-PCL lecithin oil water Sample 1 5 One 10 (camellia oil) Balance Sample 2 5 One 15 (camellia oil) Balance Sample 3 5 One 20 (camellia oil) Balance Sample 4 5 One 30 (camellia oil) Balance Sample 5 5 One 40 (camellia oil) Balance Sample 6 5 One 15 (Mayu) Balance Sample 7 5 0 20 (camellia oil) Balance

&Lt; Example 2 > Determination of morphology and particle size of nanoemulsion

(1) Sample 1, sample 3 and sample 4 were measured using an electron transmission microscope (TEM). The results are shown in FIG. 1, and dynamic light scattering was performed on samples 1, 3 to 5 The average particle size was measured using a particle size analyzer (ELS-Z2, Otsuka, Japan) and the results are shown in Fig. 2 (in Figs. 1 and 2, 10% represents sample 1 and 20% represents sample 3 , 30% represents sample 4, and 40% represents sample 5).

(2) It can be seen from FIGS. 1 and 2 that an oil-in-water emulsion having a uniform and nanometer-sized diameter is formed, and that a nano emulsion having a diameter of 300 nm can be obtained at an oil content of 20 wt% or less.

&Lt; Example 3 > Confirmation of stability of nanoemulsion

(1) The stability of the nanoemulsion was confirmed by observing changes in particle size after repeated freezing and thawing for Samples 1 to 3 and 6. One cycle of freezing and thawing was frozen at -20 ° C for 12 hours and then melted at 25 ° C for 4 hours. FIG. 3A shows experimental results for samples 1 to 3, and FIG. 3B shows experimental results for sample 6 (in FIG. 3A, 10% represents sample 1, 15% represents sample 2 , And 20% represents sample 3).

(2) Referring to FIG. 3, it can be seen that there is almost no change in particle size after repeated freeze / thaw test, so that the interfacial film composed of amphiphilic block polymer / lecithin has sufficient physical stress It can be seen that it has both ductility and rigidity to withstand.

&Lt; Example 4 > Evaluation of skin absorption rate of nanoemulsion

(1) Sample 8 was prepared in the same manner as in Sample 3, except that camellia oil containing 0.3% retinol was used. The same procedure as in Sample 7 was repeated except that camellia oil containing 0.3% retinol was used To prepare a sample 9. Each of the samples 8 and 9 was applied to a cosmetic pad (400 μl was applied), and the cosmetic pad was attached to the surface of the inner skin of the arm and absorbed. Then, immediately after application (pre), in the order of 0 h, 0.5 h, 1 h, The Raman peak intensity of retinol absorbed into the horny layer of the skin was measured using a conforcer Raman spectroscope (Model 3510, River Diagnostics, Netherlands) and the results are shown in FIG.

(2) As shown in FIG. 4, it was confirmed that retinol in the nanoemulsion containing lecithin was more absorbed into the skin horny layer. This means that the absorption rate of the nanoemulsion is improved by decreasing the particle size effect and increasing the affinity with the skin due to the addition of lecithin in addition to the spreading power of the nanoemulsion.

Example 5 Preparation of Liquid Phase Oil for Use in Nano Emulsion Production

(1) Method 1

The bark of the sweet persimmon harvested in August (fully raw raw persimmon (immature seeds)) was dried in a hot-air dryer and ground to a size of 2 x 2 cm using a grinder to prepare a scallop chip. 100 g of the scallop chip And inserted into a cylinder-shaped container having a mesh net. 200 g of horse meat fat was pulverized and mixed with 200 ml of water. The mixture was heated to 100 ° C and filtered to separate the filtrate and the residue. The separated residue was compressed using a press to obtain a pressurized liquid, Was distilled under reduced pressure to extract crude fat. The crude fat was subjected to ultrasonic treatment in an ultrasonic disperser for 3 minutes while being stirred at 60 캜 in water, hot water at 70 캜 was flowed through the container into which the persimmon chip was inserted, and then immediately passed through the humidified fat. Thereafter, the contents discharged through the container were stored at room temperature for 12 hours, the separated water was removed, and the contents in which the water was removed were stored at room temperature for 72 hours.

(2) Method 2

The same method as Experimental Method 1 was carried out except that the persimmon leaves harvested in October (a certain degree of ripe persimmon (Wan Sookwae)) was used.

(3) Method 3

The same method as in Experimental Method 1 was carried out except that no ultrasonic treatment was carried out in the course of bathing, to prepare the talc.

(4) Method 4

In the same manner as in Experimental Method 1, except that corn husk was not used for 72 hours at room temperature, ultrasonic treatment crude fat was prepared.

(5) Method 5

The husks of the sweet persimmon harvested in August (completely raw raw persimmon (immature seeds)) were dried in a hot-air dryer and pulverized into 2 × 2 cm size using a pulverizer to prepare persimmon crust chips. 100 g of the persimmon crisps and 100 g of distilled water were added to 0.8 Torr and distilled under reduced pressure at 40 ° C to prepare persimmon extract. 200 g of horse meat fat was pulverized and mixed with 200 ml of water. The mixture was heated to 100 ° C and filtered to separate the filtrate and the residue. The separated residue was compressed using a press to obtain a pressurized liquid, Was distilled under reduced pressure to extract crude fat. The crude fat was ultrasonicated for 3 minutes in an ultrasonic disperser at 60 ° C in water, mixed with 10 ml of persimmon extract, and stored at room temperature for 72 hours to prepare horse oil.

(6) Evaluation of deodorizing effect

The sensory evaluation was carried out on the talc prepared in Examples 1 to 5, and the results are shown in Table 2 below. Sensory evaluation was carried out on odor, and it was evaluated by 5 point scale method for 10 men and women of 20 ~ 40 years, and the lower score was given as the smell was worse. Table 2 below shows that the deodorizing effect of maruyu is excellent when using the persimmon peel chips or the persimmon extract, and it can be seen that there is almost no difference in deodorizing effect between persimmon peel chips and persimmon peel extract.

Method 1 Practice Method 2 Practice Method 3 Practice Method 4 Method 5 smell 3.9 3.7 3.8 1.3 4.0

(7) Evaluation of liquid hemp extraction efficiency

It was confirmed that the liquid phase and solid phase liquid phase separation was performed on the liquid prepared in Examples 1 to 5, and when the liquid phase phase separation was performed, the liquid phase was separated from the solid state phase liquid to obtain the amount of liquid phase And the results are shown in Table 3 below. As shown in Table 3, it was confirmed that the liquid phase was located on the upper side and the solid phase was located on the lower side in the case of the semi-manufactured phase manufactured by the experimental methods 1, 2 and 3. Thus, It can be seen that the liquid separation can be easily obtained without any special operation due to the layer separation. In addition, it was confirmed that Example 1 can obtain more liquid phase oil than Examples 2 and 3, and it can be seen that the liquid phase can be obtained more by using ultrasonic treatment than that of ripened shell chips of ripened and immature. have.

Method 1 Practice Method 2 Practice Method 3 Practice Method 4 Method 5 Whether the layer is separated detach detach detach Not separate Not separate Liquid horsepower (g) 25.4 18.6 19.5

Based on the results of the previous examples, a cosmetic composition containing the nanoemulsion of the present invention is prepared and presented. However, the composition of the present invention is not intended to be limited to the following formulation examples.

&Lt; Formulation Example 1 >

Formulation examples of creams containing camellia oil nanoemulsion were prepared as shown in the following Table 4.

&Lt; Formulation Example 2 >

Formulation examples of the serum containing the camellia oil nanoemulsion were prepared as shown in the following Table 5.

While the present invention has been described in connection with what is presently considered to be practical exemplary embodiments, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, Should be interpreted as belonging to the scope.

Claims (6)

In a cosmetic composition comprising a nanoemulsion,
Wherein the nanoemulsion comprises 5 to 20 parts by weight of camellia oil or talc, 0.5 to 10 parts by weight of an amphiphilic block polymer, and 60 to 85 parts by weight of water. The method of claim 1, wherein the nanoemulsion comprises
And 0.5 to 2 parts by weight of lecithin. A step of preparing a mixed solution by dissolving the amphiphilic block polymer and lecithin in a solvent at a temperature of 30 to 50 DEG C and adding a liquid horse oil or camellia oil to the mixture to prepare a mixed solution; and slowly adding water while stirring the mixed solution to form an emulsion A solvent removing step of removing the solvent from the emulsion; and a size adjusting step of reducing the particle size of the emulsion to a nanosize range by applying an external force to the solvent removed from the emulsion. &Lt; RTI ID = 0.0 &gt; emulsion. &Lt; / RTI &gt; The method of claim 3,
In the step of preparing the mixed solution, at least one selected from the group consisting of ethanol, tetrahydrofuran and methylene chloride is used,
In the emulsion preparation step, purified water is added at a rate of 400 to 600 μl / min while stirring the mixed solution at 300 to 400 rpm,
In the solvent removal step, the solvent present in the emulsion is removed by distillation under reduced pressure,
Wherein the emulsion having the solvent removed is treated with an ultrasonic dispersing machine or a high-pressure emulsifier in the sizing step. 5. The method of claim 4,
The method for producing a cosmetic composition comprising the nanoemulsion further comprises a step of obtaining a liquid phase,
In the step of refining the horse meat, the horse meat is ground, the water is mixed and heated, and the filtrate and the residue are separated by filtration. The separated residue is squeezed to obtain a pressurized liquid. The filtrate and the pressurized liquid are distilled under reduced pressure, An ultrasonic wave processing step of ultrasonic wave processing the supernatant at a high temperature; a chip heating step of adding hot water to the persimmon crisps to warm the confectionery chip; and a step of heating the crude fat obtained in the ultrasonic wave processing step Separating the water layer and the fat layer by separating the water layer and the fat layer after the crude fat filtration step and separating the separated fat layer at a room temperature for a certain period of time to separate the liquid fat into the liquid fat and the solid fat, Wherein the nano-emulsion is in the form of a powder. The method according to claim 5,
A method for producing a cosmetic composition comprising a nano emulsion, characterized in that the skin of the ginseng which has been harvested in August is dried by hot air blowing and pulverized using a pulverizer.

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