KR20180029044A - 차동 측정에 기반한 이온 센서 - Google Patents
차동 측정에 기반한 이온 센서 Download PDFInfo
- Publication number
- KR20180029044A KR20180029044A KR1020187001495A KR20187001495A KR20180029044A KR 20180029044 A KR20180029044 A KR 20180029044A KR 1020187001495 A KR1020187001495 A KR 1020187001495A KR 20187001495 A KR20187001495 A KR 20187001495A KR 20180029044 A KR20180029044 A KR 20180029044A
- Authority
- KR
- South Korea
- Prior art keywords
- micro
- reservoir
- sensor
- porous material
- channel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000005259 measurement Methods 0.000 title claims abstract description 22
- 239000011148 porous material Substances 0.000 claims abstract description 56
- 239000012088 reference solution Substances 0.000 claims abstract description 55
- 230000005669 field effect Effects 0.000 claims abstract description 15
- 239000012528 membrane Substances 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 10
- 239000000758 substrate Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 7
- 239000011159 matrix material Substances 0.000 claims description 4
- 238000007599 discharging Methods 0.000 claims 1
- 239000000243 solution Substances 0.000 abstract description 29
- 150000002500 ions Chemical class 0.000 description 45
- 239000000499 gel Substances 0.000 description 11
- 238000010586 diagram Methods 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 230000004044 response Effects 0.000 description 5
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 102100026735 Coagulation factor VIII Human genes 0.000 description 2
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 description 2
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000000017 hydrogel Substances 0.000 description 2
- -1 hydrogen ions Chemical class 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000013022 venting Methods 0.000 description 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- HBBGRARXTFLTSG-UHFFFAOYSA-N Lithium ion Chemical compound [Li+] HBBGRARXTFLTSG-UHFFFAOYSA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 108010067973 Valinomycin Proteins 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- FCFNRCROJUBPLU-UHFFFAOYSA-N compound M126 Natural products CC(C)C1NC(=O)C(C)OC(=O)C(C(C)C)NC(=O)C(C(C)C)OC(=O)C(C(C)C)NC(=O)C(C)OC(=O)C(C(C)C)NC(=O)C(C(C)C)OC(=O)C(C(C)C)NC(=O)C(C)OC(=O)C(C(C)C)NC(=O)C(C(C)C)OC1=O FCFNRCROJUBPLU-UHFFFAOYSA-N 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- CWAFVXWRGIEBPL-UHFFFAOYSA-N ethoxysilane Chemical compound CCO[SiH3] CWAFVXWRGIEBPL-UHFFFAOYSA-N 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 229910001416 lithium ion Inorganic materials 0.000 description 1
- 238000001459 lithography Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000013335 mesoporous material Substances 0.000 description 1
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000001139 pH measurement Methods 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229910001414 potassium ion Inorganic materials 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- FCFNRCROJUBPLU-DNDCDFAISA-N valinomycin Chemical compound CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@@H](C(C)C)NC(=O)[C@@H](C(C)C)OC(=O)[C@H](C(C)C)NC(=O)[C@H](C)OC(=O)[C@@H](C(C)C)NC(=O)[C@@H](C(C)C)OC(=O)[C@H](C(C)C)NC(=O)[C@H](C)OC(=O)[C@@H](C(C)C)NC(=O)[C@@H](C(C)C)OC1=O FCFNRCROJUBPLU-DNDCDFAISA-N 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/301—Reference electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/4166—Systems measuring a particular property of an electrolyte
- G01N27/4167—Systems measuring a particular property of an electrolyte pH
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Engineering & Computer Science (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ESP201531018 | 2015-07-13 | ||
| ES201531018A ES2597129B1 (es) | 2015-07-13 | 2015-07-13 | Sensor de iones de medida diferencial |
| PCT/ES2016/070527 WO2017009510A1 (es) | 2015-07-13 | 2016-07-12 | Sensor de iones de medida diferencial |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180029044A true KR20180029044A (ko) | 2018-03-19 |
Family
ID=57104055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187001495A Withdrawn KR20180029044A (ko) | 2015-07-13 | 2016-07-12 | 차동 측정에 기반한 이온 센서 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10254243B2 (https=) |
| EP (1) | EP3324177B1 (https=) |
| JP (1) | JP2018520355A (https=) |
| KR (1) | KR20180029044A (https=) |
| CN (1) | CN107850565B (https=) |
| ES (2) | ES2597129B1 (https=) |
| WO (1) | WO2017009510A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114720538B (zh) * | 2022-04-20 | 2025-02-25 | 陕西科技大学 | 一种水凝胶表面Zeta电位测试装置及其工作方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0155725A1 (en) * | 1984-02-27 | 1985-09-25 | Sentron v.o.f. | Ion concentration measurement system that employs measuring and reference field effect transistor electrodes sensitive to the same ion |
| JPS61237048A (ja) * | 1985-04-12 | 1986-10-22 | Kuraray Co Ltd | 化学物質測定用装置 |
| US4592824A (en) * | 1985-09-13 | 1986-06-03 | Centre Suisse D'electronique Et De Microtechnique S.A. | Miniature liquid junction reference electrode and an integrated solid state electrochemical sensor including the same |
| NL8602669A (nl) | 1986-10-24 | 1988-05-16 | Sentron V O F | Op een chemfet gebaseerde referentie-elektrode. |
| US4874499A (en) * | 1988-05-23 | 1989-10-17 | Massachusetts Institute Of Technology | Electrochemical microsensors and method of making such sensors |
| GB9913946D0 (en) | 1999-06-15 | 1999-08-18 | Dart Sensors Ltd | Carbon monoxide sensor |
| GB0509632D0 (en) * | 2005-05-11 | 2005-06-15 | Dart Sensors Ltd | Electrochemical sensors |
| US8470164B2 (en) * | 2008-06-25 | 2013-06-25 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| CN102854202A (zh) * | 2011-06-30 | 2013-01-02 | 物思科技发展(北京)有限公司 | 静态物质能量测试系统 |
| WO2013036598A1 (en) * | 2011-09-06 | 2013-03-14 | Telecardia, Inc. | Measurement device with sensor array |
| CN103165447B (zh) * | 2011-12-08 | 2016-08-10 | 中芯国际集成电路制造(上海)有限公司 | 鳍式场效应晶体管及其制作方法 |
| US8963216B2 (en) * | 2013-03-13 | 2015-02-24 | Life Technologies Corporation | Chemical sensor with sidewall spacer sensor surface |
| ES2542927R1 (es) | 2014-02-11 | 2015-09-09 | Consejo Superior De Investigaciones Científicas (Csic) | Sensor de iones basado en medida diferencial, método de fabricación y método de medida |
-
2015
- 2015-07-13 ES ES201531018A patent/ES2597129B1/es not_active Expired - Fee Related
-
2016
- 2016-07-12 KR KR1020187001495A patent/KR20180029044A/ko not_active Withdrawn
- 2016-07-12 JP JP2018500661A patent/JP2018520355A/ja active Pending
- 2016-07-12 CN CN201680039437.3A patent/CN107850565B/zh active Active
- 2016-07-12 EP EP16778071.7A patent/EP3324177B1/en active Active
- 2016-07-12 WO PCT/ES2016/070527 patent/WO2017009510A1/es not_active Ceased
- 2016-07-12 ES ES16778071T patent/ES2778650T3/es active Active
- 2016-07-12 US US15/743,923 patent/US10254243B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2597129B1 (es) | 2017-11-08 |
| WO2017009510A1 (es) | 2017-01-19 |
| JP2018520355A (ja) | 2018-07-26 |
| US20180209933A1 (en) | 2018-07-26 |
| ES2778650T3 (es) | 2020-08-11 |
| EP3324177B1 (en) | 2019-12-18 |
| CN107850565A (zh) | 2018-03-27 |
| ES2597129A1 (es) | 2017-01-16 |
| CN107850565B (zh) | 2020-03-20 |
| EP3324177A1 (en) | 2018-05-23 |
| US10254243B2 (en) | 2019-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20180116 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination |