KR20180022873A - 고리형 rgd 세포-결합 모티프 및 이의 용도 - Google Patents
고리형 rgd 세포-결합 모티프 및 이의 용도 Download PDFInfo
- Publication number
- KR20180022873A KR20180022873A KR1020187002495A KR20187002495A KR20180022873A KR 20180022873 A KR20180022873 A KR 20180022873A KR 1020187002495 A KR1020187002495 A KR 1020187002495A KR 20187002495 A KR20187002495 A KR 20187002495A KR 20180022873 A KR20180022873 A KR 20180022873A
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- KR
- South Korea
- Prior art keywords
- ser
- gly
- ala
- cell
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H1/00—Macromolecular products derived from proteins
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Insects & Arthropods (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Materials Engineering (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Sustainable Development (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15174072.7 | 2015-06-26 | ||
| EP15174072 | 2015-06-26 | ||
| PCT/EP2016/064543 WO2016207281A1 (en) | 2015-06-26 | 2016-06-23 | Cyclic rgd cell-binding motif and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180022873A true KR20180022873A (ko) | 2018-03-06 |
Family
ID=53513980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187002495A Ceased KR20180022873A (ko) | 2015-06-26 | 2016-06-23 | 고리형 rgd 세포-결합 모티프 및 이의 용도 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10316069B2 (https=) |
| EP (1) | EP3313869B1 (https=) |
| JP (1) | JP6863976B2 (https=) |
| KR (1) | KR20180022873A (https=) |
| CN (1) | CN108026152B (https=) |
| CA (1) | CA2990523C (https=) |
| DK (1) | DK3313869T3 (https=) |
| WO (1) | WO2016207281A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3263593A1 (en) * | 2016-07-01 | 2018-01-03 | Anna Rising | Engineered spider silk proteins and uses thereof |
| JP7029748B2 (ja) * | 2018-01-26 | 2022-03-04 | 小島プレス工業株式会社 | 植毛品及びその製造方法 |
| EP3967704A4 (en) * | 2019-06-11 | 2022-08-31 | FUJIFILM Corporation | CYCLIC PEPTIDE, CELL SCAFFOLD MATERIAL, CELL SEPARATOR MATERIAL AND CULTURE MEDIUM |
| GB2588421B (en) * | 2019-10-23 | 2021-11-03 | Neoss Ltd | Surgical membrane |
| MX2023012063A (es) | 2021-04-12 | 2024-02-01 | Biocrine Ab | Organoides de islotes pancreáticos como fábricas de proteínas. |
| CN119923461A (zh) | 2022-08-08 | 2025-05-02 | 思百博技术股份公司 | 从内分泌祖细胞的3d胰岛形成 |
| JPWO2024128081A1 (https=) * | 2022-12-16 | 2024-06-20 | ||
| CN120157740B (zh) * | 2025-05-20 | 2025-08-01 | 广州飞来爱生命科技有限公司 | 一种脐带间充质干细胞制剂及其在治疗卵巢疾病中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1465591A (zh) * | 2002-06-24 | 2004-01-07 | 三九生物科技股份有限公司 | 氨基酸序列精氨酸-甘氨酸-天冬氨酸/纤维素亲和力功能区细胞贴附因子及其制造方法 |
| CN100436477C (zh) * | 2005-03-25 | 2008-11-26 | 复旦大学附属中山医院 | 含精-甘-天冬氨酸序列环肽及其主动靶向脂质体 |
| DK1976868T3 (da) * | 2005-12-30 | 2015-04-20 | Spiber Technologies Ab | Edderkoppesilke-proteiner og fremgangsmåde til fremstilling af edderkoppesilke-proteiner |
| CN101817873A (zh) * | 2010-03-11 | 2010-09-01 | 复旦大学 | 一种促进细胞黏附的多肽及其制备方法 |
| CA2795541C (en) * | 2010-04-12 | 2020-05-26 | Spiber Technologies Ab | Spider silk protein scaffolds for eukaryotic cell culture |
| BR112014030716A2 (pt) * | 2012-06-07 | 2018-06-26 | Dcb Usa Llc | fragmentos de fibronectina modificada ou variantes e usos dos mesmos |
| WO2014027042A2 (en) * | 2012-08-17 | 2014-02-20 | Amsilk Gmbh | Use of self-assembling polypeptides as tissue adhesives |
| WO2015036619A1 (en) * | 2013-09-16 | 2015-03-19 | Spiber Technologies Ab | A method and a cell scaffold material for cell culture |
-
2016
- 2016-06-23 JP JP2018518780A patent/JP6863976B2/ja active Active
- 2016-06-23 WO PCT/EP2016/064543 patent/WO2016207281A1/en not_active Ceased
- 2016-06-23 KR KR1020187002495A patent/KR20180022873A/ko not_active Ceased
- 2016-06-23 EP EP16731887.2A patent/EP3313869B1/en active Active
- 2016-06-23 DK DK16731887.2T patent/DK3313869T3/da active
- 2016-06-23 CA CA2990523A patent/CA2990523C/en active Active
- 2016-06-23 CN CN201680049902.1A patent/CN108026152B/zh active Active
- 2016-06-23 US US15/739,057 patent/US10316069B2/en active Active
-
2019
- 2019-05-06 US US16/403,780 patent/US10662230B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2990523C (en) | 2023-01-24 |
| CA2990523A1 (en) | 2016-12-29 |
| CN108026152B (zh) | 2022-03-01 |
| US20190322710A1 (en) | 2019-10-24 |
| US10662230B2 (en) | 2020-05-26 |
| JP2018527404A (ja) | 2018-09-20 |
| CN108026152A (zh) | 2018-05-11 |
| EP3313869B1 (en) | 2021-02-17 |
| EP3313869A1 (en) | 2018-05-02 |
| JP6863976B2 (ja) | 2021-04-21 |
| US20180170977A1 (en) | 2018-06-21 |
| DK3313869T3 (da) | 2021-05-10 |
| WO2016207281A1 (en) | 2016-12-29 |
| US10316069B2 (en) | 2019-06-11 |
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| EP2844361B1 (en) | Spider silk fusion protein structures incorporating immunoglobulin fragments as affinity ligands | |
| EP2844360B1 (en) | Spider silk fusion protein structures without repetitive fragment for binding to an organic target | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20180125 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| A302 | Request for accelerated examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20210621 Comment text: Request for Examination of Application |
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| PA0302 | Request for accelerated examination |
Patent event date: 20210621 Patent event code: PA03022R01D Comment text: Request for Accelerated Examination |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20211027 Patent event code: PE09021S01D |
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| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20220218 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20211027 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |