KR20180010200A - 현탁 세포용 소규모 배양 방법 - Google Patents

현탁 세포용 소규모 배양 방법 Download PDF

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KR20180010200A
KR20180010200A KR1020177034153A KR20177034153A KR20180010200A KR 20180010200 A KR20180010200 A KR 20180010200A KR 1020177034153 A KR1020177034153 A KR 1020177034153A KR 20177034153 A KR20177034153 A KR 20177034153A KR 20180010200 A KR20180010200 A KR 20180010200A
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cell
culture
culture medium
cells
small
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KR1020177034153A
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English (en)
Korean (ko)
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슈테펜 고레트
라이너 슈타흔
슈테펜 크레예
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글리코토페 게엠베하
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Application filed by 글리코토페 게엠베하 filed Critical 글리코토페 게엠베하
Publication of KR20180010200A publication Critical patent/KR20180010200A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00—Cells for large scale production

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020177034153A 2015-05-29 2016-05-25 현탁 세포용 소규모 배양 방법 KR20180010200A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
LU92727 2015-05-29
LU92727 2015-05-29
EP16151811.3 2016-01-19
EP16151811 2016-01-19
PCT/EP2016/061763 WO2016193083A1 (en) 2015-05-29 2016-05-25 Small scale cultivation method for suspension cells

Publications (1)

Publication Number Publication Date
KR20180010200A true KR20180010200A (ko) 2018-01-30

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ID=56108615

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177034153A KR20180010200A (ko) 2015-05-29 2016-05-25 현탁 세포용 소규모 배양 방법

Country Status (10)

Country Link
US (1) US20180135091A1 (de)
EP (1) EP3303557B1 (de)
JP (1) JP6737813B2 (de)
KR (1) KR20180010200A (de)
CN (1) CN108138128A (de)
AU (1) AU2016272566A1 (de)
BR (1) BR112017023624A2 (de)
CA (1) CA2985435A1 (de)
RU (1) RU2730656C2 (de)
WO (1) WO2016193083A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017023624A2 (pt) 2015-05-29 2018-07-17 Glycotope Gmbh método de cultivo em pequena escala para células em suspensão
EP3472338B1 (de) 2016-06-20 2024-05-22 Octapharma AG Vorrichtung und verfahren zur modifizierung multipler allele
WO2018062358A1 (ja) * 2016-09-29 2018-04-05 Ｃｏａｉｄｏ株式会社 災害緊急用地域一斉架電システム
JP7317466B2 (ja) 2017-12-12 2023-07-31 株式会社日立製作所 細胞株及び培養条件のスクリーニング方法、及びその装置
CN111139216B (zh) * 2018-11-01 2024-09-03 上海药明生物技术有限公司 高通量、自动化的细胞连续培养方法及其应用
WO2020201296A1 (en) * 2019-04-01 2020-10-08 The Automation Partnership (Cambridge) Ltd. Operation process for a cell cultivation system
JP2022531464A (ja) * 2019-05-08 2022-07-06 ザイマージェン インコーポレイテッド より大きなスケールにおけるパフォーマンスの予測を改善するように小さなスケールでの微生物用の実験およびプレートモデルをデザインするためのパラメータのダウンスケーリング
CN118064651A (zh) * 2024-03-11 2024-05-24 上海迈邦生物科技有限公司 一种细胞灌流培养体系维持稳态的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5320963A (en) * 1992-11-25 1994-06-14 National Research Council Of Canada Bioreactor for the perfusion culture of cells
JP2997771B2 (ja) * 1998-06-29 2000-01-11 金沢大学長 細胞の懸濁培養方法
US20040185535A1 (en) 2003-03-21 2004-09-23 Giles Wilson Industrial-scale serum-free production of recombinant FVII in mammalian cells
US20040185534A1 (en) * 2000-10-02 2004-09-23 Knudsen Ida Molgaard Industrial-scale serum-free production of recombinant proteins in mammalian cells
WO2007071072A1 (en) 2005-12-22 2007-06-28 Corporation De L'ecole Polytechnique De Montreal High-rate perfusion bioreactor
CN101490239A (zh) * 2006-07-14 2009-07-22 帝斯曼知识产权资产管理有限公司 改进的细胞培养方法
EP2014760A1 (de) 2007-06-13 2009-01-14 CMC Biopharmaceuticals A/S Methode zur Produktion eines Biopolymers (z.B. eines Polypeptides) in einem kontinuierlichen Fermentationsprozess
EP3255153A1 (de) * 2009-11-17 2017-12-13 E. R. Squibb & Sons, L.L.C. Verfahren für erhöhte proteinproduktion
WO2012085162A1 (en) * 2010-12-21 2012-06-28 Glycotope Gmbh Methods for culturing human myeloid leukaemia cells and cells derived therefrom
EP2599651A1 (de) 2011-12-01 2013-06-05 Magna E-Car Systems GmbH & Co OG Heiz-/Kühlsystem für eine Batterie eines Kraftfahrzeugs sowie Betriebsverfahren hierfür
CN102690781B (zh) * 2012-04-28 2014-04-30 苏州金盟生物技术有限公司 一种灌流式细胞培养的培养基更换方法
CN104195187B (zh) 2014-08-01 2018-02-16 润科生物工程（福建）有限公司 沉降‑逆灌流‑放流偶联制备富含dha油脂的方法及其专用细胞沉降槽
BR112017023624A2 (pt) 2015-05-29 2018-07-17 Glycotope Gmbh método de cultivo em pequena escala para células em suspensão

Also Published As

Publication number Publication date
EP3303557B1 (de) 2021-05-05
RU2017140920A3 (de) 2019-07-17
RU2017140920A (ru) 2019-07-01
JP6737813B2 (ja) 2020-08-12
JP2018516077A (ja) 2018-06-21
US20180135091A1 (en) 2018-05-17
EP3303557A1 (de) 2018-04-11
CA2985435A1 (en) 2016-12-08
CN108138128A (zh) 2018-06-08
AU2016272566A1 (en) 2017-11-23
BR112017023624A2 (pt) 2018-07-17
WO2016193083A1 (en) 2016-12-08
RU2730656C2 (ru) 2020-08-24

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