KR20170123329A - 단백질병증을 치료하기 위한 방법 - Google Patents
단백질병증을 치료하기 위한 방법 Download PDFInfo
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- KR20170123329A KR20170123329A KR1020177027604A KR20177027604A KR20170123329A KR 20170123329 A KR20170123329 A KR 20170123329A KR 1020177027604 A KR1020177027604 A KR 1020177027604A KR 20177027604 A KR20177027604 A KR 20177027604A KR 20170123329 A KR20170123329 A KR 20170123329A
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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| US62/131,071 | 2015-03-10 | ||
| PCT/US2016/021512 WO2016145046A1 (en) | 2015-03-10 | 2016-03-09 | Methods for treating proteinopathies |
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| CN110891565A (zh) * | 2017-06-19 | 2020-03-17 | 凯诺斯医药公司 | α-突触核蛋白的调控剂 |
| TWI644673B (zh) * | 2017-07-27 | 2018-12-21 | 百朗克股份有限公司 | 頭孢曲松的用途 |
| SG11202107844UA (en) * | 2019-02-04 | 2021-08-30 | Genzyme Corp | Methods for treating symptoms and disorders associated with lysosomal storage diseases |
| PT3920912T (pt) | 2019-02-04 | 2025-09-09 | Genzyme Corp | Tratamento de ciliopatias usando inibidores da glucosilceramida sintase (gcs) |
| ES3058346T3 (es) * | 2019-11-15 | 2026-03-10 | Yuhan Corp | Derivados que tienen un resto 2,3-dihidro-1H-indeno o 2,3-dihidrobenzofurano o una sal farmacéuticamente aceptable de mismo y composiciones farmacéuticas que comprenden los mismos |
| IL295255A (en) * | 2020-02-03 | 2022-10-01 | Genzyme Corp | Methods for treating neurological symptoms associated with lysosomal storage diseases |
| EP4110317B1 (en) | 2020-02-28 | 2025-11-19 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| US12624011B2 (en) * | 2020-03-17 | 2026-05-12 | Sumitomo Pharma Co., Ltd. | Oxadiazole derivative |
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| US20230372313A1 (en) * | 2020-07-30 | 2023-11-23 | Genzyme Corporation | Methods for reducing glycosphingolipid concentration in brain tissue and methods of treatment of neurodegenerative diseases involving the same |
| US11773088B2 (en) | 2020-11-02 | 2023-10-03 | Praxis Precision Medicines, Inc. | KCNT1 inhibitors and methods of use |
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| US3538214A (en) | 1969-04-22 | 1970-11-03 | Merck & Co Inc | Controlled release medicinal tablets |
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| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| LT2685986T (lt) * | 2011-03-18 | 2020-03-10 | Genzyme Corporation | Gliukozilceramido sintazės slopiklis |
| AU2012272815B2 (en) * | 2011-06-22 | 2017-09-07 | The General Hospital Corporation | Treatment of proteinopathies |
| MA37975B2 (fr) * | 2012-09-11 | 2021-03-31 | Genzyme Corp | Inhibiteurs de synthase de glucosylcéramide |
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| HK1244217A1 (zh) | 2018-08-03 |
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| TW201642855A (zh) | 2016-12-16 |
| JP2021119185A (ja) | 2021-08-12 |
| EP3267983A1 (en) | 2018-01-17 |
| PL3267983T3 (pl) | 2024-05-13 |
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| EP4349408A2 (en) | 2024-04-10 |
| JP2018507886A (ja) | 2018-03-22 |
| MX2017011598A (es) | 2017-12-20 |
| PT3267983T (pt) | 2024-03-12 |
| WO2016145046A1 (en) | 2016-09-15 |
| IL254393A0 (en) | 2017-11-30 |
| CA2978883A1 (en) | 2016-09-15 |
| ES2973101T3 (es) | 2024-06-18 |
| US20180036295A1 (en) | 2018-02-08 |
| CN107872976A (zh) | 2018-04-03 |
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