KR20170042605A - 알킬화된 인플루엔자 백신 - Google Patents

알킬화된 인플루엔자 백신 Download PDF

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Publication number
KR20170042605A
KR20170042605A KR1020177004533A KR20177004533A KR20170042605A KR 20170042605 A KR20170042605 A KR 20170042605A KR 1020177004533 A KR1020177004533 A KR 1020177004533A KR 20177004533 A KR20177004533 A KR 20177004533A KR 20170042605 A KR20170042605 A KR 20170042605A
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KR
South Korea
Prior art keywords
influenza
alkylating agent
influenza virus
influenza vaccine
hemagglutinin
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KR1020177004533A
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English (en)
Korean (ko)
Inventor
브룩 밀너
조나단 헤인즈
스티븐 하우저
자네트 포리
Original Assignee
사노피 파스퇴르 인코포레이티드
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Publication of KR20170042605A publication Critical patent/KR20170042605A/ko
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16061Methods of inactivation or attenuation
    • C12N2760/16063Methods of inactivation or attenuation by chemical treatment

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020177004533A 2014-08-18 2015-08-18 알킬화된 인플루엔자 백신 Withdrawn KR20170042605A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462038753P 2014-08-18 2014-08-18
US62/038,753 2014-08-18
PCT/US2015/045689 WO2016028776A1 (en) 2014-08-18 2015-08-18 Alkylated influenza vaccines

Publications (1)

Publication Number Publication Date
KR20170042605A true KR20170042605A (ko) 2017-04-19

Family

ID=54008038

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177004533A Withdrawn KR20170042605A (ko) 2014-08-18 2015-08-18 알킬화된 인플루엔자 백신

Country Status (9)

Country Link
US (1) US10124056B2 (enExample)
EP (1) EP3182998A1 (enExample)
JP (1) JP2017525766A (enExample)
KR (1) KR20170042605A (enExample)
CN (1) CN106794241A (enExample)
AU (1) AU2015305690A1 (enExample)
CA (1) CA2957570A1 (enExample)
SG (1) SG11201701279VA (enExample)
WO (1) WO2016028776A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7403733B2 (ja) * 2017-09-04 2023-12-25 国立感染症研究所長 インフルエンザhaスプリットワクチンの製造方法
WO2019045090A1 (ja) * 2017-09-04 2019-03-07 公益財団法人ヒューマンサイエンス振興財団 インフルエンザhaスプリットワクチンの製造方法
CN111511800B (zh) 2017-10-30 2023-11-28 武田药品工业株式会社 灭活脂包膜病毒的环境相容性去污剂
TW202011986A (zh) 2018-07-23 2020-04-01 公益財團法人日本健康科學振興財團 包含流感疫苗之組合物
PH12021552094A1 (en) 2019-03-04 2022-05-30 Japan As Represented By Director General Of Nat Institute Of Infectious Diseases Method for preparing influenza ha split vaccine
CN112618709B (zh) * 2019-09-24 2023-11-03 华南理工大学 一种猪口服接种疫苗缓释佐剂及其制备方法与应用
CN112708599B (zh) * 2019-10-25 2022-02-18 中国农业大学 一株禽流感病毒疫苗株及其应用
US12428372B2 (en) 2022-04-14 2025-09-30 Saudi Arabian Oil Company ODSO acid medium, ODSO acid mixture medium, and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62221636A (ja) 1986-03-20 1987-09-29 Chemo Sero Therapeut Res Inst B型肝炎ウイルス抗原蛋白の可溶化方法
FR2773156B1 (fr) * 1997-12-26 2000-03-31 Biovacs Inc Nouveaux immunogenes anti-retroviraux (toxoides), nouveaux procedes de preparation et application a la prevention et au traitement du sida
JPWO2003014338A1 (ja) 2001-08-02 2004-11-25 アンジェスMg株式会社 不活性化ウイルスエンベロープの製造方法
EP1481985A1 (en) 2003-05-28 2004-12-01 Innogenetics N.V. Modified hepatitis C virus (HCV) NS3 for medical treatment
DK1725581T3 (da) * 2004-03-17 2008-11-10 Crucell Holland Bv Ny assay til adskillelse og kvantificering af hæmagglutinin-antigener
GB0502901D0 (en) * 2005-02-11 2005-03-16 Nat Inst Biological Standards & Control New detoxification method
CN101161285A (zh) * 2007-09-06 2008-04-16 上海荣盛生物技术有限公司 流感病毒裂解疫苗
CN102858961A (zh) 2010-05-03 2013-01-02 葛兰素史密丝克莱恩生物有限公司 新方法
WO2011154976A2 (en) 2010-06-08 2011-12-15 Panacea Biotec Limited Improved influenza vaccine
CN102406931B (zh) * 2011-11-25 2014-02-05 成都康华生物制品有限公司 大流行流感病毒裂解疫苗

Also Published As

Publication number Publication date
US20160045590A1 (en) 2016-02-18
CA2957570A1 (en) 2016-02-25
WO2016028776A1 (en) 2016-02-25
SG11201701279VA (en) 2017-03-30
EP3182998A1 (en) 2017-06-28
JP2017525766A (ja) 2017-09-07
US10124056B2 (en) 2018-11-13
CN106794241A (zh) 2017-05-31
AU2015305690A1 (en) 2017-03-02

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Date Code Title Description
PA0105 International application

Patent event date: 20170217

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination