KR20170019457A - 땅콩 알레르기의 치료를 위한 핵산 - Google Patents

땅콩 알레르기의 치료를 위한 핵산 Download PDF

Info

Publication number
KR20170019457A
KR20170019457A KR1020177001547A KR20177001547A KR20170019457A KR 20170019457 A KR20170019457 A KR 20170019457A KR 1020177001547 A KR1020177001547 A KR 1020177001547A KR 20177001547 A KR20177001547 A KR 20177001547A KR 20170019457 A KR20170019457 A KR 20170019457A
Authority
KR
South Korea
Prior art keywords
ser
leu
arg
glu
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020177001547A
Other languages
English (en)
Korean (ko)
Inventor
윌리엄 헤알
테리 헤이랜드
Original Assignee
이뮤노믹 쎄라퓨틱스, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이뮤노믹 쎄라퓨틱스, 인크. filed Critical 이뮤노믹 쎄라퓨틱스, 인크.
Publication of KR20170019457A publication Critical patent/KR20170019457A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/06Fusion polypeptide containing a localisation/targetting motif containing a lysosomal/endosomal localisation signal
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/35Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020177001547A 2014-06-23 2015-06-23 땅콩 알레르기의 치료를 위한 핵산 Withdrawn KR20170019457A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462015981P 2014-06-23 2014-06-23
US62/015,981 2014-06-23
PCT/US2015/037240 WO2015200357A2 (en) 2014-06-23 2015-06-23 Nucleic acids for treatment of peanut allergies

Publications (1)

Publication Number Publication Date
KR20170019457A true KR20170019457A (ko) 2017-02-21

Family

ID=53546722

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177001547A Withdrawn KR20170019457A (ko) 2014-06-23 2015-06-23 땅콩 알레르기의 치료를 위한 핵산

Country Status (9)

Country Link
US (2) US20170304432A1 (enExample)
EP (1) EP3157558A2 (enExample)
JP (1) JP2017521064A (enExample)
KR (1) KR20170019457A (enExample)
CN (1) CN106459994A (enExample)
AU (2) AU2015280143A1 (enExample)
BR (1) BR112016030439A2 (enExample)
CA (1) CA2952726A1 (enExample)
WO (1) WO2015200357A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210142000A (ko) * 2019-03-13 2021-11-23 소마젠 인크 알레르기 치료를 위한 에피토프-기반 접근법 및 크론병에 대한 억제제
KR20220063460A (ko) * 2020-11-10 2022-05-17 (주)프로테옴텍 밀가루 유래의 오메가-5-글리아딘의 신규 에피토프 중합체 및 이의 용도

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10143742B2 (en) 2015-02-20 2018-12-04 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10166286B2 (en) 2015-02-20 2019-01-01 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10149904B2 (en) 2015-02-20 2018-12-11 The Board Of Trusteees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US11452774B2 (en) 2015-02-20 2022-09-27 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
WO2017186808A1 (en) * 2016-04-27 2017-11-02 Allergy Therapeutics (Uk) Limited Treatment of peanut allergy
US11826423B2 (en) 2016-11-16 2023-11-28 Immunomic Therapeutics, Inc. Nucleic acids for treatment of allergies
WO2018195527A1 (en) * 2017-04-22 2018-10-25 Immunomic Therapeutics, Inc. Improved lamp constructs
KR20200016224A (ko) 2017-05-02 2020-02-14 이뮤노믹 쎄라퓨틱스, 인크. 암 항원을 포함하는 lamp (리소솜 연관 막 단백질) 구축물
US11382934B2 (en) 2017-07-18 2022-07-12 Before Brands, Inc. Methods for making mixed allergen compositions
CA3099495A1 (en) 2018-05-11 2019-11-14 Astellas Pharma Inc. Nucleic acid for treating mite allergy
WO2019216396A1 (ja) 2018-05-11 2019-11-14 アステラス製薬株式会社 甲殻類アレルギー治療のための核酸
US12398195B2 (en) 2018-05-15 2025-08-26 Immunomic Therapeutics, Inc. Lamp constructs comprising allergens
CN109115737B (zh) * 2018-07-27 2021-03-26 青岛大学 一种三螺旋pH生物传感器及其应用
CA3127337A1 (en) 2019-01-23 2020-07-30 Before Brands, Inc. Methods for making mixed allergen compositions
CN112225815A (zh) * 2020-09-30 2021-01-15 四川携光生物技术有限公司 一种牛奶、小麦、花生及大豆过敏原融合蛋白及其构建方法、应用
CN114438088B (zh) * 2020-11-03 2025-05-23 韩达 一种溶酶体靶向的核酸嵌合体的制备及应用
WO2022099695A1 (en) * 2020-11-16 2022-05-19 Jiangsu Cell Tech Medical Research Institute Co., Ltd. Cd164 fusion and uses thereof
CN115057927B (zh) * 2022-05-30 2024-02-20 南开大学 一种花生过敏原Ara h1特异性纳米抗体及其应用
WO2025199077A1 (en) * 2024-03-19 2025-09-25 Modernatx, Inc. Tolerizing antigen specific immunotherapies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018185A1 (en) * 1992-03-03 1993-09-16 The Salk Institute For Biological Studies Receptor internalization signals
US20060251667A1 (en) * 2002-08-29 2006-11-09 Chua Kaw Y Recombinant nucleic acid useful for inducing protective immune response against allergens
HUE052481T2 (hu) * 2012-06-15 2021-04-28 Immunomic Therapeutics Inc Nukleinsavak, allergiák kezelésére
US9774230B2 (en) * 2015-11-25 2017-09-26 Caterpillar Inc. Generator set having coupling member between flywheel and generator

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210142000A (ko) * 2019-03-13 2021-11-23 소마젠 인크 알레르기 치료를 위한 에피토프-기반 접근법 및 크론병에 대한 억제제
KR20220063460A (ko) * 2020-11-10 2022-05-17 (주)프로테옴텍 밀가루 유래의 오메가-5-글리아딘의 신규 에피토프 중합체 및 이의 용도

Also Published As

Publication number Publication date
JP2017521064A (ja) 2017-08-03
EP3157558A2 (en) 2017-04-26
AU2020204277A1 (en) 2020-07-16
BR112016030439A2 (pt) 2018-07-17
US20190298821A1 (en) 2019-10-03
AU2015280143A1 (en) 2017-01-05
WO2015200357A3 (en) 2016-04-21
US20170304432A1 (en) 2017-10-26
CN106459994A (zh) 2017-02-22
CA2952726A1 (en) 2015-12-30
WO2015200357A2 (en) 2015-12-30

Similar Documents

Publication Publication Date Title
KR20170019457A (ko) 땅콩 알레르기의 치료를 위한 핵산
EP2861240B1 (en) Nucleic acids for treatment of allergies
US7446185B2 (en) Her2/neu target antigen and use of same to stimulate an immune response
US20040258688A1 (en) Enhanced antigen delivery and modulation of the immune response therefrom
US20040242481A1 (en) Use of hmgb1 for the activation of dendritic cells
JP2001503741A (ja) アレルギー性肺疾患を治療するための方法
KR101195400B1 (ko) 암배아 항원 융합물 및 이의 용도
WO2014187743A1 (en) Gastrin peptide immunogenic composition
US20060251667A1 (en) Recombinant nucleic acid useful for inducing protective immune response against allergens
EP2412811B1 (en) Dna vaccine for alzheimer's disease
JP6353510B2 (ja) アレルギー治療のための核酸
US20240287166A1 (en) Dna antibody constructs for use against plasmodium parasites
CZ20022192A3 (cs) Konstrukt pro vakcinaci nukleovými kyselinami a vakcina
CA3238159A1 (en) Sars cov-2 vaccine, associated polynucleotides, and methods of use
HK1243732A1 (zh) 编码hnp-1或hnp-2或hnp-3的dna质粒、细菌生产者、镇痛剂(变体)
CN114630675A (zh) 乙型肝炎病毒(hbv)疫苗和抗pd-1或抗pd-l1抗体的组合
AU2009273128A1 (en) Constructing a DNA chimera for vaccine development against Leishmaniasis and tuberculosis
JP2015214555A (ja) アレルギー治療のための核酸
HK40075526A (en) Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 or anti-pd-l1 antibody
MXPA06009202A (en) Carcinoembryonic antigen fusions proteins and uses thereof

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20170118

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination