KR20170010575A - Blood separating vial for extracting PRP easily - Google Patents

Abstract

The present invention relates to a blood separation container ensuring easy extraction of platelet-rich plasma (PRP) from a lateral side. Owing to a PRP suctioning hole provided at a central portion of the blood separation container, a user gets to easily extract PRP after placing a syringe.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood separating vessel for extracting PRP,

More particularly, the present invention relates to a blood separation container that allows a PRP extraction port to be provided at the center of a blood separation container to easily extract PRP .

PRP (platelet-rich plasma, abbreviated as 'PRP' hereinafter) refers to the platelet-rich portion of plasma, which is not a special processing or producing material but a component that can be obtained in the blood of the patient. The PRP obtained through the centrifugal separator using blood from the patient's own blood contains platelets 3 to 8 times as large as the platelet counts contained in plasma in the normal blood.

Platelets function to release growth factors involved in the recovery of injured tissue. These growth factors promote the tissue's natural recovery potential. For example, the composition of the regeneration environment, the promotion of blood vessel formation, the involvement of skin tissue and cell growth, and the promotion of regeneration of connective tissue. Recently, it has been used for cosmetic surgery. It is known that PRP is commonly used for tissue transplantation such as fat or cartilage transplantation, thereby increasing the engraftment rate of tissue. It is also used as an agent for improving skin aging by injecting directly into the skin to cause fine wrinkles. Since these PRPs are autologous blood components, side effects such as infection or rejection during the injection process are rare and have been used through many experiments and validation procedures.

In such a situation, conventionally, when extracting plasma by centrifuging the blood, it is difficult to extract the plasma only at a certain distance from the portion of the plasma that forms the boundary with the red blood cells, and to discard the rest, and to extract the desired amount. Further, since it is difficult to fix the position of the injector to be extracted, it is difficult to accurately extract it, and other components are sometimes extracted together with plasma.

On the other hand, Korean Patent Laid-Open No. 10-2011-0009651 and the like disclose a prior art relating to a blood separation container.

SUMMARY OF THE INVENTION The present invention has been conceived to solve the problems of the prior art as described above, and it is an object of the present invention to provide a PRP extracting port at the center of a blood separation vessel to fix a syringe to a blood separation vessel, It has its purpose.

According to an aspect of the present invention, there is provided a blood separation container comprising: an upper housing for providing a space in which blood components are located when blood is centrifuged; A lower housing providing a space in which blood components are located when the blood is centrifuged; And a PRP extraction pipe connecting the upper housing and the lower housing to form a PRP extraction port for extracting the PRP.

Here, the PRP extraction tube is made of a transparent material, and it is possible to visually confirm that the PRP is extracted.

In addition, the PRP extraction port and the PRP extraction port may be horizontally formed to accommodate a syringe needle inserted into the PRP extraction port.

In addition, a height adjusting means is provided at a lower end of the lower housing to adjust a height at which erythrocytes and PRP are located.

Finally, the apparatus further comprises a magnifying glass for connecting the upper housing and the lower housing together with the PRP extracting tube, and observing the PRP extracted from the PRP extracting tube.

The blood separation container according to the present invention has the following effects.

First, PRP can be extracted as precisely as desired. Among the components of the blood separated by centrifugation, the red blood cells are located at the bottom of the container, the buffy coat and the plasma are sequentially disposed thereon, and the plasma is separated into PRP and PPP (platelet-poor plasma, platelet-poor plasma). In such a situation, since the syringe is positioned in the vertical direction with respect to the paper, the plasma is extracted. Therefore, depending on the position of the syringe needle, PRP and erythrocytes may be extracted at the boundary between PRP and red blood cells. In addition, the position of the syringe needle may be changed due to the fine hand motion of the extracting person. That is, in the vertical direction, it is difficult not only to position the tip of the syringe needle properly at a point intended by the PRP extraction tube but also to maintain the position of the syringe needle unless the hand or arm is supported at any point. However, the blood separation vessel according to the present invention is advantageous in that the PRP is extracted by coupling the syringe at the side. That is, since the syringe needle is inserted from the side, it is easy to place the syringe needle at the intended point of the person extracting from the PRP extraction tube, and when the syringe needle is inserted, the PRP extractor supports the syringe needle, It is also possible to prevent some of the syringe needle from being shaken as compared with the situation where the hand is held in the state without the support means. Therefore, compared to the conventional extraction method, the syringe needle can be precisely positioned at an intended position of the PRP extraction tube, and it is easy to maintain the position, so that only the desired amount of PRP can be accurately extracted.

Second, PRP can be efficiently extracted for a certain amount of blood. Conventionally, in order to prevent the extraction of red blood cells described in the first effect, PRP has to be extracted at a predetermined distance from red blood cells. After this extraction, the PRP adjacent to the red blood cell is not extracted because it is thought that the red blood cells are extracted together. Therefore, it is impossible to extract PRP as much as possible from the amount of extracted blood. However, in the blood separation container according to the present invention, the height adjustment means is provided in the lower housing, so that the PRP is extracted from the side, and the PRP can be extracted again by pushing up the red blood cells and the PRP by the extracted amount. can do.

Third, extraction is easy by fixing the syringe to be extracted. In the present invention, a mounting groove is formed at a horizontal position with respect to the PRP extraction pit outlet. This mounting groove is a groove that allows the needle of the syringe to be attached to the PRP extraction port, and the syringe thus mounted can stably extract the PRP from the blood separation container.

1 is a perspective view of a blood separation container according to an embodiment of the present invention;
FIG. 2 is an exploded perspective view of the blood separation container shown in FIG. 1. FIG.
Fig. 3 is a rear view of the blood separation container shown in Fig. 1; Fig.
FIG. 4 is a perspective view showing a state in which a syringe is combined in the blood separation container shown in FIG. 1. FIG.
Fig. 5 is a view showing the coupling of the height adjusting means coupled to the lower housing in the blood separation container shown in Fig. 1. Fig.
6 is a view showing a state in which PRP is extracted by a syringe after the position of the PRP is adjusted by the height adjusting means after the blood is centrifuged.

Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings. However, some configurations which are not related to the gist of the present invention may be omitted or compressed, but the configurations omitted are not necessarily required for the present invention, and they may be combined by a person having ordinary skill in the art to which the present invention belongs. .

FIG. 1 is a perspective view of a blood separation container according to an embodiment of the present invention, FIG. 2 is an exploded perspective view of the blood separation container shown in FIG. 1, FIG. 3 is a rear view of the blood separation container shown in FIG. 4 is a perspective view showing a state in which a syringe is combined in the blood separation container shown in FIG. 1, and FIG. 5 is a combined view of a height adjustment means coupled to a lower housing in the blood separation container shown in FIG.

1 to 5, a blood separation container (hereinafter, referred to as 'blood separation container') that facilitates PRP extraction in terms of the present invention includes a cap 110, an upper housing 100, a PRP extraction tube A display unit 200, a magnifying glass 210, a mounting groove 220, a lower housing 300, and a height adjusting unit 310.

The cap 110 is located at the top of the blood separation vessel 1 according to the present invention and is connected to the upper housing 100 and seals or opens the blood separation vessel 1 through the sealing means 113. In this cap 110, a blood inlet 111 and an air outlet 112 are formed to inject blood collected from a human with the syringe 400 into the blood inlet 111. At this time, the air outlet 112 is a hole through which the air escapes to the outside so that the blood can be smoothly injected into the lower housing 300 through the upper housing 100.

The upper housing 100 is made of a transparent plastic material capable of observing the inside of the upper housing 100 and is configured such that blood injected from the blood inlet 111 first passes through the upper housing 100. The upper portion of the upper housing 100 includes a cap 110, And the lower part is formed with an upper bottleneck part 101 which is narrowed in accordance with the diameter of the PRP extraction pipe 200.

Like the upper housing 100, the PRP extraction tube 200 is made of a transparent material and its inside can be visually observed. The PRP extraction tube 200 connects the upper bottleneck portion 101 of the upper housing 100 and the lower bottleneck portion 301 of the lower housing 300 to allow the blood injected into the blood inlet 111 to pass through the lower housing 300 ). ≪ / RTI > In addition, a PRP extraction port 201 is formed on a side surface of the PRP extraction tube 200 so that the PRP 500 can be extracted by inserting a needle of the injection device 400. Since the PRP extraction port 201 is made of a soft silicone material, the PRP extraction port 201 can easily be inserted when the syringe needle is plugged into the PRP extraction port 201, and the PRP extraction port 201 is completely wrapped around the needle, Is prevented.

The magnifying glass 210 is horizontally positioned with respect to the PRP extraction tube 200 by enlarging the PRP 500 extracted from the PRP extraction tube 200 to the syringe 400 and allowing the user to more easily observe the extracted PRP 500 with the naked eye. Therefore, the magnifying glass 210 helps the person who extracts the PRP 500 to precisely control the extraction of the PRP 500.

The mounting groove 220 is a place for mounting the needle of the syringe 400 inserted into the PRP extraction tube 200 and the position of the mounted syringe 400 is fixed so that the PRP 500 can be stably extracted. In addition, the mounting groove 220 helps to avoid changing the position of the needle of the syringe 400 when a situation occurs in which the position of the PRP 500 should be raised during the extraction of the PRP 500 by the extracting person . That is, if there is no mounting groove 220 in the process of extraction, one hand will hold the blood separation container 1 while the other hand will hold the syringe 400, unless someone holds the syringe 400. Therefore, it is troublesome to insert the syringe 400 into the PRP extraction port 201 after the height of the PRP 500 is adjusted by the hand holding the syringe 400 by placing the syringe 400 on a safe place. However, in the present invention, since the mounting groove 220 is provided, the position of the PRP 500 can be elevated by using the height adjusting means 310 by holding the syringe 400 and holding the syringe 400, It is possible to facilitate the extraction of the PRP 500 without performing troublesome work of pulling out and then plugging the PRP 500 again.

The lower housing 300 is also made of a transparent plastic material and contains the blood initially injected through the lower bottleneck 301, and the red blood cells 600 are located at the time of centrifugation.

The height adjusting means 310 is coupled to the lower end of the lower housing 300. The height adjusting means 310 can adjust the volume of the lower housing 300 by adjusting the height. That is, the volume of the lower housing 300 changes as the pressing portion 318 is raised or lowered by the adjusting bolt. At this time, the height of the lowered PRP 500 after the PRP 500 is extracted is set to the pressing portion 318 push up the erythrocytes 600 so that the PRP 500 is positioned at a horizontal position with respect to the PRP extraction port 201.

The blood separation container according to the embodiment of the present invention described above will be further described by explaining the use process.

FIG. 6 is a view showing a state in which PRP is extracted by a syringe after adjusting the position of the PRP by the height adjusting means after blood is centrifuged.

6, the blood is first injected into the blood separation container 1 and collected into the upper housing 100 and the lower housing 300. As shown in FIG. That is, the syringe 400 is brought into close contact with the blood injection port 111 formed in the cap 110, and blood drawn from a person is injected. At this time, since the anticoagulant is contained in the syringe 400 in advance, the drawn blood is not solidified. The air outlet 112 formed in the cap 110 discharges the air inside the blood separation vessel 1 during blood injection so that the blood ejected from the syringe 400 is smoothly injected into the blood separation vessel 1 .

The injected blood is divided into individual blood components through a centrifuge. That is, the red blood cells 600 are collected at the lowermost part of the blood separation vessel 1, the buffy coat 700 containing the white blood cells and the plasma partially forms on the red blood cells 600, and the plasma is formed on the buffy coat 700 Respectively. In addition, the plasma again forms a layer with the PRP 500 divided downward and the PPP divided upward. At this time, in order to extract the PRP 500, the adjustment bolt 311 of the height adjusting means 310 is rotated to change the volume of the lower housing 300. The red blood cells 600 pushed up by the pressing portion 318 as the pressing portion 318 rises and the red blood cells 600 pushed up by the pressing portion 318 push the PRP 500 The PRP 500 can be extracted by inserting the injector 400 into the PRP extraction port 201 because the extractor pushes up the PRP extraction pipe 200 to raise it. This can be seen in FIG. If the PRP 500 is not positioned in the PRP extraction tube 200 after the extraction of the PRP 500, the PRP 500 remaining in the blood separation vessel 1 is transferred to the PRP 500 using the height adjustment means 310, So that it can be extracted to the position of the extraction tube 200 to be extracted.

Referring to the structure of the height adjusting means 310, an adjustment bolt 311 for adjusting the height of the liquid in the blood separation container 1 by a user is located at the lowermost part. The adjustment bolt 311 is provided with a snap ring seat 312 on which the snap ring 316 can be seated, and the snap ring 316 is seated upon engagement. The snap ring 316 is positioned between the male screw portion 313 and the stationary bracket 314 and functions to fix the male screw portion 313 to the stationary bracket 314. [

The fixing bracket 314 coupled to the adjustment bolt 311 has a housing coupling protrusion 315 formed around the fixing bolt 311 so as to be inserted into the four bracket fixing grooves 302 formed in the lower housing 300 and fixed to the lower housing 300 do. When the adjustment bolt 311 is rotated, the fixing bracket 314 guides the adjustment bolt 311 to rotate only in the position without changing the position, as the fixing bracket 314 is fixed to the lower housing 300.

Also, the female threaded portion 317 coupled to the male threaded portion 313 of the adjustment bolt 311 is moved around by the pressing portion 318 coupled thereto. That is, when the male screw portion 313 fixed by the fixing bracket 314 is rotated, the male screw portion 313 does not move but moves only by the female screw portion 317 so that it can rise and fall. This movement is the same principle that one of the joints between the existing bolt and the nut is fixed and rotated and the other is loosened or tightened. Therefore, in the present invention, the adjustment bolt 311 is rotated to change the volume of the housing 300 to the pressing portion 318 coupled to the female threaded portion 317, so that the PRP (500) to the PRP extraction tube (200), and extracts the raised PRP (500) to the syringe (400).

As described above in detail, the blood separation vessel 1 according to the present invention can accurately extract PRP 500 by a desired amount. Among the components of the blood separated through centrifugation, the red blood cells 600 are located on the lower side of the vessel, the buffy coat 700 and the plasma are sequentially positioned thereon, and the plasma is separated into PRP 500 and PPP. In such a situation, conventionally, the injector 400 is positioned in a direction perpendicular to the paper surface to extract plasma, so that the PRP 500 as well as the red blood cells 600 may be extracted depending on the position of the needle of the injector 400 there was. In addition, the position of the needle of the syringe 400 may be changed due to the minute hand motion of the extracting person. That is, in the vertical direction, it is difficult to properly place the tip of the syringe needle 400 at any point intended by the PRP extraction tube 200, and even if it is positioned, It was difficult to maintain. However, the blood separation container 1 according to the present invention is advantageous in that the PRP 500 is extracted by coupling the syringe 400 on the side. That is, since the needle of the syringe 400 is inserted from the side, it is easy to position the needle of the syringe 400 at a position intended by the person extracting from the PRP extraction tube 200, and when the needle of the syringe 400 is inserted, Since the extraction tool 201 supports the needle of the syringe 400, it is possible to prevent some of the needle of the syringe 400 from being shaken as compared with a situation where the needle is held by the hand without a supporting means as in the prior art. Therefore, compared to the conventional extraction method, the needle of the syringe 400 can be precisely positioned at an intended position of the PRP extraction tube 200, and it is easy to maintain the position of the needle. Therefore, the PRP 500 can be precisely Can be extracted.

In addition, the PRP 500 can be efficiently extracted with respect to a constant amount of blood. Conventionally, in order to prevent the extraction of the red blood cells 600 described in the first effect, the PRP 500 has to be extracted at a predetermined distance from the red blood cells 600. After the extraction, the PRP 500 adjacent to the red blood cell 600 may not be extracted because the red blood cells 600 are extracted together. Therefore, it is impossible to extract PRP (500) as much as possible from the amount of extracted blood. However, in the blood separation container 1 according to the present invention, the lower housing 300 is provided with the height adjusting means 310, and the PRP 500 is extracted from the side, and the red blood cells 600 and the PRP 500 are pushed up by the extracted amount It is possible to extract the PRP 500 again so that more PRP 500 can be extracted as compared with the conventional method.

In addition, extraction is easy by fixing the injector 400 to be extracted. In the present invention, a mounting groove 220 is formed at a horizontal position with respect to the PRP extraction port 201. This mounting groove 220 is a groove for coupling and mounting the needle of the syringe 400 to the PRP extracting hole 201. The syringe 400 thus mounted stably extracts plasma from the blood separation container 1 can do.

The foregoing description of the preferred embodiments of the present invention has been presented for the purpose of illustration and it will be apparent to those skilled in the art that various modifications, additions and substitutions are possible within the spirit and scope of the invention, And additions should be considered as falling within the scope of the claims of the present invention.

1: blood separation container
100: upper housing
101: Upper bottleneck
110: Plug
111: Blood inlet
112: air outlet
113: Sealing means
200: PRP extraction tube
201: PRP extraction port
210: Magnifying glass
220: Mounting groove
300: Lower housing
301: Lower bottleneck
302: Bracket fixing groove
310: height adjustment means
311: Adjusting bolt
312: snap ring seat portion
313: Male threads
314: Fixed bracket
315: housing coupling projection
316: Snap ring
317: Female threads
318:
400: syringe
500: PRP
600: red blood cells
700: Buffy coat

Claims (5)

An upper housing providing a space in which blood components are located when the blood is centrifuged;
A lower housing providing a space in which blood components are located when the blood is centrifuged; And
And a PRP extraction pipe connecting the upper housing and the lower housing and having a PRP extraction port for extracting the PRP.
The method according to claim 1,
Wherein the PRP extraction tube is made of a transparent material and can visually confirm that the PRP is extracted.
The method according to claim 1,
Wherein the PRP extraction port and the PRP extraction port are formed horizontally and vertically so that the syringe needle inserted into the PRP extraction port can be mounted.
The method according to claim 1,
And a height adjustment means is provided at a lower end of the lower housing to adjust a height at which erythrocytes and PRP are positioned through a change in the volume of the lower housing.
The method according to claim 1,
And a magnifying glass connecting the upper housing and the lower housing together with the PRP extracting tube and observing the PRP extracted from the PRP extracting tube. .

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