KR20160135230A - 암의 치료를 위한 병용 요법으로서의 에리불린 및 mTOR 억제제의 용도 - Google Patents

암의 치료를 위한 병용 요법으로서의 에리불린 및 mTOR 억제제의 용도 Download PDF

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KR20160135230A
KR20160135230A KR1020167027369A KR20167027369A KR20160135230A KR 20160135230 A KR20160135230 A KR 20160135230A KR 1020167027369 A KR1020167027369 A KR 1020167027369A KR 20167027369 A KR20167027369 A KR 20167027369A KR 20160135230 A KR20160135230 A KR 20160135230A
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South Korea
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pharmaceutically acceptable
cancer
acceptable salt
eribulin
tumor
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KR1020167027369A
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Korean (ko)
Inventor
브루스 에이. 리틀필드
야스히로 후나하시
토시미츠 우에나카
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에자이 알앤드디 매니지먼트 가부시키가이샤
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Publication of KR20160135230A publication Critical patent/KR20160135230A/ko
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020167027369A 2014-03-03 2015-03-02 암의 치료를 위한 병용 요법으로서의 에리불린 및 mTOR 억제제의 용도 Withdrawn KR20160135230A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461947398P 2014-03-03 2014-03-03
US61/947,398 2014-03-03
PCT/US2015/018335 WO2015134399A1 (en) 2014-03-03 2015-03-02 Use of eribulin and mtor inhibitors as combination therapy for the treatment of cancer

Publications (1)

Publication Number Publication Date
KR20160135230A true KR20160135230A (ko) 2016-11-25

Family

ID=54055761

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167027369A Withdrawn KR20160135230A (ko) 2014-03-03 2015-03-02 암의 치료를 위한 병용 요법으로서의 에리불린 및 mTOR 억제제의 용도

Country Status (11)

Country Link
US (1) US20170071903A1 (OSRAM)
EP (1) EP3113775A4 (OSRAM)
JP (1) JP2017507151A (OSRAM)
KR (1) KR20160135230A (OSRAM)
CN (1) CN106029070A (OSRAM)
AU (1) AU2015225436A1 (OSRAM)
CA (1) CA2940983A1 (OSRAM)
IL (1) IL247586A0 (OSRAM)
RU (1) RU2016136504A (OSRAM)
SG (1) SG11201607298QA (OSRAM)
WO (1) WO2015134399A1 (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2522663T3 (pl) 2004-06-03 2015-08-31 Eisai R&D Man Co Ltd Produkty pośrednie do otrzymywania halichondryny B
HRP20161157T1 (hr) 2009-03-30 2016-11-18 Eisai R&D Management Co., Ltd. Liposomski pripravak
AU2014299699B2 (en) 2013-06-26 2019-10-10 Eisai R&D Management Co., Ltd. Use of eribulin and lenvatinib as combination therapy for treatment of cancer
WO2017188350A1 (ja) * 2016-04-28 2017-11-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 腫瘍の成長を抑制する方法
EP3713565A1 (en) 2017-11-20 2020-09-30 Basilea Pharmaceutica International AG Pharmaceutical combinations for use in the treatment of neoplastic diseases
JP2022506829A (ja) * 2018-11-09 2022-01-17 ジー1、セラピューティクス、インコーポレイテッド エリブリンと選択的cdk4/6阻害剤との組合せを使用する癌の処置のための治療レジメン
US11083705B2 (en) 2019-07-26 2021-08-10 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
US12036204B2 (en) 2019-07-26 2024-07-16 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009532503A (ja) * 2006-04-05 2009-09-10 ノバルティス アクチエンゲゼルシャフト 癌を処置するための治療剤の組合せ
EP2470177B1 (en) * 2009-08-27 2015-07-15 Bionomics Limited Combination therapy for treating proliferative diseases
EP2680839A1 (en) * 2011-03-02 2014-01-08 Morphotek, Inc. Co -administration of eribulin and farletuzumab for the treatment of breast cancer
EP2833915A1 (en) * 2012-04-02 2015-02-11 Merrimack Pharmaceuticals, Inc. Dosage and administration of monospecific and bispecific anti-igf-1r and anti-erbb3 antibodies

Also Published As

Publication number Publication date
WO2015134399A1 (en) 2015-09-11
RU2016136504A (ru) 2018-04-03
EP3113775A1 (en) 2017-01-11
IL247586A0 (en) 2016-11-30
CA2940983A1 (en) 2015-09-11
AU2015225436A1 (en) 2016-09-08
CN106029070A (zh) 2016-10-12
RU2016136504A3 (OSRAM) 2018-10-25
EP3113775A4 (en) 2017-08-23
SG11201607298QA (en) 2016-09-29
JP2017507151A (ja) 2017-03-16
US20170071903A1 (en) 2017-03-16

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Date Code Title Description
PA0105 International application

Patent event date: 20160930

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination