KR20160086818A - 요법에 대한 반응의 결정 방법 - Google Patents

요법에 대한 반응의 결정 방법 Download PDF

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Publication number
KR20160086818A
KR20160086818A KR1020167009042A KR20167009042A KR20160086818A KR 20160086818 A KR20160086818 A KR 20160086818A KR 1020167009042 A KR1020167009042 A KR 1020167009042A KR 20167009042 A KR20167009042 A KR 20167009042A KR 20160086818 A KR20160086818 A KR 20160086818A
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South Korea
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mice
erk
ratio
subject
fmr1
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Korean (ko)
Inventor
야론 다니엘리
조안나 추만
조나단 루빈
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알코브라 리미티드
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Priority claimed from US14/038,258 external-priority patent/US20150073023A1/en
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Publication of KR20160086818A publication Critical patent/KR20160086818A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
KR1020167009042A 2013-09-09 2014-09-09 요법에 대한 반응의 결정 방법 Withdrawn KR20160086818A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361875384P 2013-09-09 2013-09-09
US61/875,384 2013-09-09
US14/038,258 US20150073023A1 (en) 2013-09-09 2013-09-26 Method Of Treating Fragile X Syndrome And Related Disorders
US14/038,258 2013-09-26
US201461991351P 2014-05-09 2014-05-09
US61/991,351 2014-05-09
PCT/US2014/054816 WO2015035402A1 (en) 2013-09-09 2014-09-09 Methods of determining response to therapy

Publications (1)

Publication Number Publication Date
KR20160086818A true KR20160086818A (ko) 2016-07-20

Family

ID=52629036

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020167009042A Withdrawn KR20160086818A (ko) 2013-09-09 2014-09-09 요법에 대한 반응의 결정 방법
KR1020167009040A Withdrawn KR20160078956A (ko) 2013-09-09 2014-09-09 취약 x 증후군 및 관련 장애의 치료 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020167009040A Withdrawn KR20160078956A (ko) 2013-09-09 2014-09-09 취약 x 증후군 및 관련 장애의 치료 방법

Country Status (12)

Country Link
EP (2) EP3043792A2 (OSRAM)
JP (2) JP2016530536A (OSRAM)
KR (2) KR20160086818A (OSRAM)
CN (2) CN105917225A (OSRAM)
AU (2) AU2014315026A1 (OSRAM)
CA (2) CA2922901A1 (OSRAM)
EA (2) EA201690557A1 (OSRAM)
IL (2) IL244343A0 (OSRAM)
MX (2) MX2016003006A (OSRAM)
SG (2) SG11201601605YA (OSRAM)
TW (2) TW201606304A (OSRAM)
WO (2) WO2015033224A2 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015014835A1 (en) * 2013-07-31 2015-02-05 Basf Se Luminescent diazabenzimidazole carbene metal complexes
US20150073023A1 (en) 2013-09-09 2015-03-12 Alcobra Ltd. Method Of Treating Fragile X Syndrome And Related Disorders
CN108538365A (zh) * 2017-03-24 2018-09-14 华东师范大学 一种基于数据分析技术的自闭症社交能力评估系统
EP3773538A1 (en) * 2018-04-13 2021-02-17 Healx Limited Treatment of fragile x syndrome
KR20190121569A (ko) * 2018-04-18 2019-10-28 건국대학교 글로컬산학협력단 아그마틴 및 이의 약학적으로 허용 가능한 염을 포함하는 취약 x 증후군 예방 또는 치료용 약학조성물
AU2019280980B2 (en) 2018-06-07 2025-02-27 Ovid Therapeutics Inc. Use of (S)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid and related compounds, (1S,3S)-3-amino-4-(difluoromethylidene) cyclopentane-1-carboxylic acid and vigabatrin in the treatment of developmental disorders
EP4088721B1 (en) * 2020-01-08 2025-09-17 Neuroventi Composition for treating fragile x syndrome or related developmental disorders, comprising lisuride compound as active ingredient
WO2021158059A1 (ko) * 2020-02-07 2021-08-12 건국대학교 글로컬산학협력단 릴메니딘 화합물을 유효성분으로 포함하는 취약 x 증후군 또는 관련 발달 장애 치료용 조성물
AU2021301406A1 (en) * 2020-06-29 2023-02-02 Harmony Biosciences Management, Inc. Treatment of fragile x syndrome with cannabidiol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1131856B (it) 1980-06-30 1986-06-25 Baldacci Lab Spa Composizione farmaceutica per il trattamento di intossicazioni alcooliche
WO2002043507A2 (en) * 2000-11-30 2002-06-06 The Health Research Institute Nutrient supplements and methods for treating autism and for preventing the onset of autism
IL187159A0 (en) 2007-07-03 2009-02-11 Gur Megiddo Use of metadoxine in relief of alcohol intoxication
BRPI1015231A2 (pt) * 2009-06-25 2018-02-20 Alcobra Ltd método para tratamento, suavização de sintomas, alívio, melhoria e prevenção de uma doença, distúrbio ou condição cognitiva

Also Published As

Publication number Publication date
TW201606304A (zh) 2016-02-16
CA2923421A1 (en) 2015-03-12
IL244453A0 (en) 2016-04-21
EA201690557A1 (ru) 2016-07-29
EP3043792A2 (en) 2016-07-20
WO2015033224A2 (en) 2015-03-12
WO2015033224A3 (en) 2015-07-02
JP2016530291A (ja) 2016-09-29
CN105517546A (zh) 2016-04-20
CA2922901A1 (en) 2015-03-12
JP2016530536A (ja) 2016-09-29
KR20160078956A (ko) 2016-07-05
AU2014316779A1 (en) 2016-03-17
CN105917225A (zh) 2016-08-31
AU2014315026A1 (en) 2016-03-24
IL244343A0 (en) 2016-04-21
EA201690559A1 (ru) 2016-08-31
EP3044589A1 (en) 2016-07-20
TW201605443A (zh) 2016-02-16
MX2016003002A (es) 2016-09-08
SG11201601830PA (en) 2016-04-28
MX2016003006A (es) 2016-06-10
WO2015035402A1 (en) 2015-03-12
SG11201601605YA (en) 2016-04-28

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PA0105 International application

Patent event date: 20160406

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid