KR20160047521A - 세포 증식성 질환의 치료를 위한 alk 억제제 및 cdk 억제제의 조합물 - Google Patents
세포 증식성 질환의 치료를 위한 alk 억제제 및 cdk 억제제의 조합물 Download PDFInfo
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US201361871275P | 2013-08-28 | 2013-08-28 | |
| US61/871,275 | 2013-08-28 | ||
| PCT/US2014/053244 WO2015031666A1 (en) | 2013-08-28 | 2014-08-28 | Combination of an alk inhibitor and a cdk inhibitor for the treatment of cell proliferative diseases |
Publications (1)
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| KR20160047521A true KR20160047521A (ko) | 2016-05-02 |
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| KR1020167007656A Withdrawn KR20160047521A (ko) | 2013-08-28 | 2014-08-28 | 세포 증식성 질환의 치료를 위한 alk 억제제 및 cdk 억제제의 조합물 |
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| KR101772134B1 (ko) | 2015-04-14 | 2017-08-29 | 한국화학연구원 | N2-(2-메톡시페닐)피리미딘 유도체, 이의 제조 방법 및 이를 유효 성분으로 함유하는 암의 예방 또는 치료용 약학적 조성물 |
| WO2016167511A2 (ko) * | 2015-04-14 | 2016-10-20 | 한국화학연구원 | N2-(2-메톡시페닐)피리미딘 유도체, 이의 제조 방법 및 이를 유효 성분으로 함유하는 암의 예방 또는 치료용 약학적 조성물 |
| WO2017112948A1 (en) * | 2015-12-24 | 2017-06-29 | University Of Florida Research Foundation, Inc. | Improved aav production using suspension adapted cells |
| US11395821B2 (en) | 2017-01-30 | 2022-07-26 | G1 Therapeutics, Inc. | Treatment of EGFR-driven cancer with fewer side effects |
| WO2019136451A1 (en) | 2018-01-08 | 2019-07-11 | G1 Therapeutics, Inc. | G1t38 superior dosage regimes |
| BR112021018168B1 (pt) | 2019-03-21 | 2023-11-28 | Onxeo | Composição farmacêutica, combinação e kit compreendendo uma molécula dbait e um inibidor de quinase para o tratamento de câncer |
| CA3130706A1 (en) * | 2019-04-04 | 2020-10-08 | Dana-Farber Cancer Institute, Inc. | Cdk2/5 degraders and uses thereof |
| CA3159348A1 (en) | 2019-11-08 | 2021-05-14 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| US20230019999A1 (en) | 2019-11-18 | 2023-01-19 | Chugai Seiyaku Kabushiki Kaisha | Combination drug |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| WO2021176349A1 (en) * | 2020-03-05 | 2021-09-10 | Pfizer Inc. | Combination of an anaplastic lymphoma kinase inhibitor and a cyclin dependent kinase inhibitor |
| CN116261455B (zh) * | 2020-09-25 | 2024-11-01 | 苏州亚盛药业有限公司 | 一种药物组合物及其在治疗癌症中的用途 |
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| ME00811B (me) * | 2006-12-08 | 2012-03-20 | Novartis Ag | JEDINJENJA l KOMPOZICIJE KAO INHIBITORI PROTEIN KINAZE |
| KR101364277B1 (ko) * | 2006-12-08 | 2014-02-21 | 아이알엠 엘엘씨 | 단백질 키나제 억제제로서의 화합물 |
| KR101353857B1 (ko) * | 2008-08-22 | 2014-01-21 | 노파르티스 아게 | Ｃｄｋ 억제제로서 피롤로피리미딘 화합물 |
| CA2761896A1 (en) * | 2009-05-13 | 2010-11-18 | The University Of North Carolina At Chapel Hill | Cyclin dependent kinase inhibitors and methods of use |
| AU2011240735B2 (en) * | 2010-04-13 | 2015-01-29 | Novartis Ag | Combination comprising a cyclin dependent kinase 4 or cyclin dependent kinase (CDK4/6) inhibitor and an mTOR inhibitor for treating cancer |
| BR112013019643B1 (pt) * | 2011-02-02 | 2022-04-19 | Novartis Ag | Uso de inibidores de álcali |
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- 2014-08-28 KR KR1020167007656A patent/KR20160047521A/ko not_active Withdrawn
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- 2014-08-28 US US14/913,828 patent/US20160361314A1/en not_active Abandoned
- 2014-08-28 CA CA2922684A patent/CA2922684A1/en not_active Abandoned
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- 2018-07-16 US US16/035,774 patent/US20180318305A1/en not_active Abandoned
- 2018-09-27 AU AU2018236813A patent/AU2018236813A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN106029099A (zh) | 2016-10-12 |
| RU2016110874A3 (enExample) | 2018-06-27 |
| RU2016110874A (ru) | 2017-10-04 |
| MX2016002580A (es) | 2016-10-26 |
| JP6479812B2 (ja) | 2019-03-06 |
| AU2018236813A1 (en) | 2018-10-18 |
| EP3038652A1 (en) | 2016-07-06 |
| US20160361314A1 (en) | 2016-12-15 |
| WO2015031666A1 (en) | 2015-03-05 |
| CA2922684A1 (en) | 2015-03-05 |
| JP2016529285A (ja) | 2016-09-23 |
| US20180318305A1 (en) | 2018-11-08 |
| AU2017219093A1 (en) | 2017-09-14 |
| AU2014312261A1 (en) | 2016-03-10 |
| BR112016004358A8 (pt) | 2020-02-11 |
| EP3038652B1 (en) | 2018-03-21 |
| ES2674361T3 (es) | 2018-06-29 |
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