KR20160029128A - 이중특이적 cd3 및 cd19 항원 결합 구조체 - Google Patents

이중특이적 cd3 및 cd19 항원 결합 구조체 Download PDF

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KR20160029128A
KR20160029128A KR1020167003567A KR20167003567A KR20160029128A KR 20160029128 A KR20160029128 A KR 20160029128A KR 1020167003567 A KR1020167003567 A KR 1020167003567A KR 20167003567 A KR20167003567 A KR 20167003567A KR 20160029128 A KR20160029128 A KR 20160029128A
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antigen
binding
cell
construct
cells
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고든 유곤 엔지
서짓 비마라오 디지트
토마스 스프레터 폰 그루덴스타인
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자임워크스 인코포레이티드
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    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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KR1020167003567A 2013-07-12 2014-07-11 이중특이적 cd3 및 cd19 항원 결합 구조체 Withdrawn KR20160029128A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361845948P 2013-07-12 2013-07-12
US61/845,948 2013-07-12
US201461927877P 2014-01-15 2014-01-15
US61/927,877 2014-01-15
US201461978719P 2014-04-11 2014-04-11
US61/978,719 2014-04-11
PCT/US2014/046436 WO2015006749A2 (en) 2013-07-12 2014-07-11 Bispecific cd3 and cd19 antigen binding contructs

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Publication Number Publication Date
KR20160029128A true KR20160029128A (ko) 2016-03-14

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KR1020167003567A Withdrawn KR20160029128A (ko) 2013-07-12 2014-07-11 이중특이적 cd3 및 cd19 항원 결합 구조체

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US (1) US20160355588A1 (enExample)
EP (1) EP3019622A4 (enExample)
JP (1) JP2016531100A (enExample)
KR (1) KR20160029128A (enExample)
CN (1) CN105531374A (enExample)
AU (1) AU2014287011A1 (enExample)
BR (1) BR112016000666A2 (enExample)
CA (1) CA2917886A1 (enExample)
MX (1) MX2016000272A (enExample)
RU (1) RU2016104130A (enExample)
WO (1) WO2015006749A2 (enExample)

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US9914785B2 (en) 2012-11-28 2018-03-13 Zymeworks Inc. Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
TWI682941B (zh) 2013-02-01 2020-01-21 美商再生元醫藥公司 含嵌合恆定區之抗體
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KR102813816B1 (ko) * 2013-07-05 2025-05-29 젠맵 에이/에스 인간화 또는 키메라 cd3 항체
HUE050159T2 (hu) 2013-12-17 2020-11-30 Genentech Inc Anti-CD3 antitestek és alkalmazási eljárások
US20160326249A1 (en) * 2014-01-15 2016-11-10 Zymeworks Inc. Bi-specific cd3 and cd19 antigen-binding constructs
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TWI754319B (zh) * 2014-03-19 2022-02-01 美商再生元醫藥公司 用於腫瘤治療之方法及抗體組成物
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ES2809455T3 (es) 2014-11-17 2021-03-04 Regeneron Pharma Métodos para tratamiento tumoral usando anticuerpo biespecífico CD3xCD20
CN107660214B (zh) * 2015-01-08 2022-02-08 根马布股份公司 针对cd3和cd20的双特异性抗体
DK3277725T3 (da) 2015-03-30 2021-01-11 Regeneron Pharma Konstante tungkædeområder med reduceret binding til FC-gammareceptorer
HRP20191800T1 (hr) * 2015-05-13 2019-12-27 Ablynx N.V. Polipeptidi koji regrutiraju t stanice koji se temelje na tcr alfa/beta reaktivnosti
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TW201718647A (zh) 2015-06-16 2017-06-01 建南德克公司 抗-cll-1抗體及使用方法
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