KR20150089005A - H1n1에 대한 계산적으로 최적화되고 넓은 반응성의 항원 - Google Patents

H1n1에 대한 계산적으로 최적화되고 넓은 반응성의 항원 Download PDF

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KR20150089005A
KR20150089005A KR1020157012693A KR20157012693A KR20150089005A KR 20150089005 A KR20150089005 A KR 20150089005A KR 1020157012693 A KR1020157012693 A KR 1020157012693A KR 20157012693 A KR20157012693 A KR 20157012693A KR 20150089005 A KR20150089005 A KR 20150089005A
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ser
asn
leu
influenza
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테드 엠. 로스
도날드 엠. 카터 제이알.
코레이 제이. 크레바르
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유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션
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    • C07—ORGANIC CHEMISTRY
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
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    • C12N2760/16011—Orthomyxoviridae
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01018—Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020157012693A 2012-11-27 2013-11-27 H1n1에 대한 계산적으로 최적화되고 넓은 반응성의 항원 Withdrawn KR20150089005A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261730186P 2012-11-27 2012-11-27
US61/730,186 2012-11-27
PCT/US2013/072279 WO2014085616A1 (en) 2012-11-27 2013-11-27 Computationally optimized broadly reactive antigens for h1n1 influenza

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KR20150089005A true KR20150089005A (ko) 2015-08-04

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KR1020157012693A Withdrawn KR20150089005A (ko) 2012-11-27 2013-11-27 H1n1에 대한 계산적으로 최적화되고 넓은 반응성의 항원

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US (3) US9309290B2 (enExample)
EP (1) EP2925773B1 (enExample)
JP (2) JP2016505538A (enExample)
KR (1) KR20150089005A (enExample)
CN (1) CN104797594A (enExample)
AU (2) AU2013352179B2 (enExample)
CA (1) CA2891682A1 (enExample)
HK (1) HK1212708A1 (enExample)
IN (1) IN2015DN03070A (enExample)
MX (1) MX2015005056A (enExample)
RU (1) RU2015124805A (enExample)
SG (1) SG11201503989PA (enExample)
WO (1) WO2014085616A1 (enExample)

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* Cited by examiner, † Cited by third party
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US8883171B2 (en) * 2010-09-14 2014-11-11 University of Pittsburgh—of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for influenza
EP2721158B1 (en) * 2011-06-20 2017-05-03 University of Pittsburgh - Of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for h1n1 influenza
IN2014DN07399A (enExample) 2012-03-30 2015-04-24 Univ Pittsburgh
WO2016100922A1 (en) * 2014-12-19 2016-06-23 Oregon Health & Science University Synergistic co-administration of computationally optimized broadly reactive antigens for h1n1 influenza
CN108290932A (zh) 2015-06-09 2018-07-17 圣诺菲·帕斯图尔公司 优化编码工程改造的流感蛋白的核苷酸序列的方法
US11116832B2 (en) 2016-06-03 2021-09-14 Sanofi Pasteur Inc. Modification of engineered influenza hemagglutinin polypeptides

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ATE376059T1 (de) 2000-06-23 2007-11-15 Wyeth Corp Assemblierung von wildtyp und chimären influenzavirus-ähnlichen partikeln (vlps)
US20050181459A1 (en) 2002-06-11 2005-08-18 Matthew Baker Method for mapping and eliminating T cell epitopes
US8592197B2 (en) 2003-07-11 2013-11-26 Novavax, Inc. Functional influenza virus-like particles (VLPs)
EP1851238A4 (en) 2005-02-24 2008-12-31 Univ Massachusetts FLUID NUCLEIC ACIDS, POLYPEPTIDES AND USES THEREOF
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US8883171B2 (en) * 2010-09-14 2014-11-11 University of Pittsburgh—of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for influenza
EP2721158B1 (en) * 2011-06-20 2017-05-03 University of Pittsburgh - Of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for h1n1 influenza
AU2013217166B2 (en) 2012-02-07 2017-04-06 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Computationally optimized broadly reactive antigens for H3N2, H2N2, and B influenza viruses
US9566327B2 (en) 2012-02-13 2017-02-14 University of Pittsburgh—of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for human and avian H5N1 influenza
IN2014DN07399A (enExample) * 2012-03-30 2015-04-24 Univ Pittsburgh

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CA2891682A1 (en) 2014-06-05
AU2013352179A8 (en) 2015-05-28
US20160166677A1 (en) 2016-06-16
RU2015124805A (ru) 2017-01-13
EP2925773B1 (en) 2018-12-26
US10017544B2 (en) 2018-07-10
SG11201503989PA (en) 2015-06-29
AU2013352179A1 (en) 2015-05-14
IN2015DN03070A (enExample) 2015-10-02
EP2925773A4 (en) 2016-06-08
JP2016505538A (ja) 2016-02-25
EP2925773A1 (en) 2015-10-07
US20140147459A1 (en) 2014-05-29
HK1212708A1 (zh) 2016-06-17
US9566328B2 (en) 2017-02-14
WO2014085616A1 (en) 2014-06-05
JP2018183149A (ja) 2018-11-22
AU2018201876A1 (en) 2018-04-12
AU2013352179B2 (en) 2017-12-21
MX2015005056A (es) 2015-07-23
CN104797594A (zh) 2015-07-22
US20170114102A1 (en) 2017-04-27
US9309290B2 (en) 2016-04-12

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Patent event date: 20150514

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