KR20150060579A - 4-(3-(3-플루오로페닐)-5,5-디메틸-4-옥소-4,5-디하이드로푸란-2-일)벤젠설폰아마이드의 제조 방법 - Google Patents

4-(3-(3-플루오로페닐)-5,5-디메틸-4-옥소-4,5-디하이드로푸란-2-일)벤젠설폰아마이드의 제조 방법 Download PDF

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Publication number
KR20150060579A
KR20150060579A KR1020140165226A KR20140165226A KR20150060579A KR 20150060579 A KR20150060579 A KR 20150060579A KR 1020140165226 A KR1020140165226 A KR 1020140165226A KR 20140165226 A KR20140165226 A KR 20140165226A KR 20150060579 A KR20150060579 A KR 20150060579A
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South Korea
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compound
formula
reaction
carried out
hours
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KR1020140165226A
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English (en)
Korean (ko)
Inventor
홍용래
노성구
조중명
Original Assignee
화일약품주식회사
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Publication of KR20150060579A publication Critical patent/KR20150060579A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58—One oxygen atom, e.g. butenolide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020140165226A 2013-11-26 2014-11-25 4-(3-(3-플루오로페닐)-5,5-디메틸-4-옥소-4,5-디하이드로푸란-2-일)벤젠설폰아마이드의 제조 방법 KR20150060579A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20130144940 2013-11-26
KR1020130144940 2013-11-26

Publications (1)

Publication Number Publication Date
KR20150060579A true KR20150060579A (ko) 2015-06-03

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ID=53199334

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020140165226A KR20150060579A (ko) 2013-11-26 2014-11-25 4-(3-(3-플루오로페닐)-5,5-디메틸-4-옥소-4,5-디하이드로푸란-2-일)벤젠설폰아마이드의 제조 방법

Country Status (2)

Country Link
KR (1) KR20150060579A (fr)
WO (1) WO2015080435A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200091980A (ko) * 2019-01-23 2020-08-03 주식회사 엔지켐생명과학 폴마콕시브의 제조 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6222048B1 (en) * 1995-12-18 2001-04-24 Merck Frosst Canada & Co. Diaryl-2-(5H)-furanones as Cox-2 inhibitors
DZ3265A1 (fr) * 1999-04-14 2000-10-19 Pacific Corp Derives de 4,5-diaryl-3(2h)-furanone comme inhibiteurs de cyclo-oxygenase-2
KR20100096512A (ko) * 2009-02-24 2010-09-02 크리스탈지노믹스(주) 4,5-디아릴-3(2ｈ)-퓨라논 유도체 또는 그의 약학적으로 허용가능한 염을 포함하는 인지능력 개선용 약학 조성물

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200091980A (ko) * 2019-01-23 2020-08-03 주식회사 엔지켐생명과학 폴마콕시브의 제조 방법

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WO2015080435A1 (fr) 2015-06-04

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