KR20140109430A - Casp2에 대한 이중-가닥 rna 화합물 및 그 용도 - Google Patents

Casp2에 대한 이중-가닥 rna 화합물 및 그 용도 Download PDF

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KR20140109430A
KR20140109430A KR1020147019172A KR20147019172A KR20140109430A KR 20140109430 A KR20140109430 A KR 20140109430A KR 1020147019172 A KR1020147019172 A KR 1020147019172A KR 20147019172 A KR20147019172 A KR 20147019172A KR 20140109430 A KR20140109430 A KR 20140109430A
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eye
compound
glaucoma
administered
ocular
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샤이 에를리치
제임스 디. 톰슨
라비아 오즈덴
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쿠아크 파마수티칼스 인코퍼레이티드
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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KR1020147019172A 2012-01-04 2013-01-03 Casp2에 대한 이중-가닥 rna 화합물 및 그 용도 Ceased KR20140109430A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261582886P 2012-01-04 2012-01-04
US61/582,886 2012-01-04
US201261596231P 2012-02-08 2012-02-08
US61/596,231 2012-02-08
PCT/US2013/020012 WO2013103632A1 (en) 2012-01-04 2013-01-03 Double-stranded rna compounds to casp2 and uses thereof

Related Child Applications (1)

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KR1020197035560A Division KR102202004B1 (ko) 2012-01-04 2013-01-03 Casp2에 대한 이중-가닥 rna 화합물 및 그 용도

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KR20140109430A true KR20140109430A (ko) 2014-09-15

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KR1020147019172A Ceased KR20140109430A (ko) 2012-01-04 2013-01-03 Casp2에 대한 이중-가닥 rna 화합물 및 그 용도
KR1020197035560A Active KR102202004B1 (ko) 2012-01-04 2013-01-03 Casp2에 대한 이중-가닥 rna 화합물 및 그 용도

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US (2) US9382542B2 (enExample)
EP (1) EP2800812A1 (enExample)
JP (2) JP2015507478A (enExample)
KR (2) KR20140109430A (enExample)
CN (1) CN104053776A (enExample)
AU (1) AU2013206951B2 (enExample)
BR (1) BR112014016640A2 (enExample)
CA (1) CA2858627C (enExample)
EA (1) EA036003B1 (enExample)
IL (1) IL233142B (enExample)
NZ (1) NZ625980A (enExample)
WO (1) WO2013103632A1 (enExample)

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Publication number Priority date Publication date Assignee Title
WO2015136255A1 (en) * 2014-03-11 2015-09-17 The University Of Birmingham Combined inhibition of caspase-2 and caspase-6 in neuroprotection and axon regeneration
US20180193270A1 (en) 2016-11-29 2018-07-12 PureTech Health LLC Exosomes for delivery of therapeutic agents
CN118460652B (zh) * 2024-07-10 2024-10-22 凯莱英医药集团(天津)股份有限公司 一种治疗非动脉性缺血性视神经病变的siRNA的制备方法

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US6444776B1 (en) 1998-12-21 2002-09-03 Novartis Ag Organic polymers
IT1305306B1 (it) * 1999-03-17 2001-05-04 Farmigea Spa Uso della pirenoxina per la protezione dei tessuti corneali ininterventi di fotocheratectomia.
US6444676B1 (en) * 1999-12-20 2002-09-03 Iok-Hou Pang Use of PARP inhibitors in the treatment of glaucoma
JP2005527639A (ja) * 2001-11-02 2005-09-15 インサート セラピューティクス インコーポレイテッド Rna干渉の治療的利用のための方法及び組成物
EP2530155B1 (en) * 2002-11-25 2016-03-16 Masafumi Matsuo ENA nucleic acid drugs modifying splicing in mRNA precursor
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GB0403041D0 (en) * 2004-02-11 2004-03-17 Milner Anne J Induction of apoptosis
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NZ625980A (en) 2015-05-29
JP6774928B2 (ja) 2020-10-28
CA2858627C (en) 2020-12-01
CN104053776A (zh) 2014-09-17
WO2013103632A1 (en) 2013-07-11
CA2858627A1 (en) 2013-07-11
US20140371439A1 (en) 2014-12-18
EP2800812A1 (en) 2014-11-12
IL233142A0 (en) 2014-07-31
AU2013206951A1 (en) 2014-07-03
JP2018099117A (ja) 2018-06-28
EA036003B1 (ru) 2020-09-11
US9382542B2 (en) 2016-07-05
KR20190137940A (ko) 2019-12-11
US10570394B2 (en) 2020-02-25
US20160304879A1 (en) 2016-10-20
IL233142B (en) 2019-01-31
BR112014016640A2 (pt) 2021-03-16
AU2013206951B2 (en) 2016-11-24
JP2015507478A (ja) 2015-03-12
EA201491048A1 (ru) 2015-09-30
KR102202004B1 (ko) 2021-01-12

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