KR20140063861A - 조혈줄기세포 및 조혈전구세포의 생체 외 증식 방법 - Google Patents

조혈줄기세포 및 조혈전구세포의 생체 외 증식 방법 Download PDF

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KR20140063861A
KR20140063861A KR1020147010617A KR20147010617A KR20140063861A KR 20140063861 A KR20140063861 A KR 20140063861A KR 1020147010617 A KR1020147010617 A KR 1020147010617A KR 20147010617 A KR20147010617 A KR 20147010617A KR 20140063861 A KR20140063861 A KR 20140063861A
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cells
picoline
hpc
hsc
hematopoietic
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Korean (ko)
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멜린다 엘. 터스키
마크 에이. 커클랜드
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사이토메트릭스 피티와이 리미티드
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Publication of KR20140063861A publication Critical patent/KR20140063861A/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/145—Thrombopoietin [TPO]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2306—Interleukin-6 (IL-6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/59—Lectins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020147010617A 2011-09-22 2012-09-21 조혈줄기세포 및 조혈전구세포의 생체 외 증식 방법 Withdrawn KR20140063861A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2011903899 2011-09-22
AU2011903899A AU2011903899A0 (en) 2011-09-22 Cell culture & expansion
PCT/AU2012/001135 WO2013040644A1 (en) 2011-09-22 2012-09-21 Method for the ex vivo expansion of hematopoietic stem and progenitor cells

Publications (1)

Publication Number Publication Date
KR20140063861A true KR20140063861A (ko) 2014-05-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147010617A Withdrawn KR20140063861A (ko) 2011-09-22 2012-09-21 조혈줄기세포 및 조혈전구세포의 생체 외 증식 방법

Country Status (10)

Country Link
US (1) US9518250B2 (https=)
EP (1) EP2748309A4 (https=)
JP (1) JP6112462B2 (https=)
KR (1) KR20140063861A (https=)
CN (1) CN104114694A (https=)
AU (1) AU2012313347A1 (https=)
CA (1) CA2885665A1 (https=)
IL (1) IL231668A0 (https=)
SG (1) SG11201400851PA (https=)
WO (1) WO2013040644A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016178914A1 (en) * 2015-05-01 2016-11-10 Cesca Therapeutics, Inc. Intramuscular adaminstration of autologous bone marrw for treatment
US10669528B2 (en) * 2015-06-25 2020-06-02 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
US20180230433A1 (en) * 2015-08-05 2018-08-16 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Use of dermatopontin for maintaining hematopoietic stem and/or progenitor cells in culture
WO2018191440A1 (en) * 2017-04-11 2018-10-18 President And Fellows Of Harvard College In vivo gene editing of blood progenitors
CN110093313B (zh) * 2018-01-29 2023-04-14 华南生物医药研究院 促进造血干/祖细胞分化为红系细胞的诱导培养基及应用
US12486519B2 (en) 2018-08-18 2025-12-02 President And Fellows Of Harvard College In situ gene editing
WO2021247749A1 (en) * 2020-06-02 2021-12-09 Cornell University Methods for expanding hematopoietic stem cells
CN115861151B (zh) * 2021-09-23 2025-10-17 鸿海精密工业股份有限公司 细胞采收提醒方法及系统

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US20050137126A1 (en) * 2003-04-09 2005-06-23 Natlmmune A/S Treatment of SARS in individuals
US20060205071A1 (en) * 2003-07-17 2006-09-14 Gamida-Cell Ltd. Methods for ex-vivo expanding stem/progenitor cells
IL161903A0 (en) * 2003-07-17 2005-11-20 Gamida Cell Ltd Ex vivo progenitor and stem cell expansion for usein the treatment of disease of endodermally- deri ved organs
CN1297659C (zh) * 2004-02-11 2007-01-31 上海伯瑞生物技术发展有限公司 一种造血细胞灌注培养方法和装置
WO2006045064A2 (en) 2004-10-20 2006-04-27 Whitehead Institute For Biomedical Research Cultured hematopoietic stem cells and method for expansion and analysis thereof
WO2007066352A1 (en) * 2005-12-06 2007-06-14 Department Of Biotechnology A method for preservation of human hematopoietic stem or progenitor cells
JP2008237136A (ja) * 2007-03-28 2008-10-09 Foundation For Biomedical Research & Innovation ヒト造血細胞の培養方法
WO2008149129A1 (en) * 2007-06-08 2008-12-11 Nova Thera Limited Cell expansion
CN101508975A (zh) * 2009-03-26 2009-08-19 大连理工大学 一种低氧条件下微囊化成骨细胞支持和调控造血干/祖细胞体外扩增的方法
EP2440930B1 (en) * 2009-06-10 2014-08-13 Rigshospitalet Ficolin-3 assay
WO2011030581A1 (ja) 2009-09-09 2011-03-17 シャープ株式会社 ジェスチャー判定装置およびその方法
US9062287B2 (en) 2009-09-11 2015-06-23 Takara Bio Inc. Process for production of natural killer cells

Also Published As

Publication number Publication date
AU2012313347A1 (en) 2014-05-08
EP2748309A4 (en) 2015-03-11
US20140286915A1 (en) 2014-09-25
WO2013040644A1 (en) 2013-03-28
IL231668A0 (en) 2014-05-28
CN104114694A (zh) 2014-10-22
JP2014527820A (ja) 2014-10-23
JP6112462B2 (ja) 2017-04-12
EP2748309A1 (en) 2014-07-02
SG11201400851PA (en) 2014-04-28
US9518250B2 (en) 2016-12-13
CA2885665A1 (en) 2013-03-28

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