KR20140054179A - 핵산 나노- 및 마이크로-기술에 관한 조성물 및 방법 - Google Patents

핵산 나노- 및 마이크로-기술에 관한 조성물 및 방법 Download PDF

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Publication number
KR20140054179A
KR20140054179A KR1020147005854A KR20147005854A KR20140054179A KR 20140054179 A KR20140054179 A KR 20140054179A KR 1020147005854 A KR1020147005854 A KR 1020147005854A KR 20147005854 A KR20147005854 A KR 20147005854A KR 20140054179 A KR20140054179 A KR 20140054179A
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South Korea
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dna
nucleic acid
artificial sequence
synthetic oligonucleotide
oligonucleotides
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Korean (ko)
Inventor
펭 인
디밍 웨이
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프레지던트 앤드 펠로우즈 오브 하바드 칼리지
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
KR1020147005854A 2011-08-05 2012-08-02 핵산 나노- 및 마이크로-기술에 관한 조성물 및 방법 Withdrawn KR20140054179A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161515435P 2011-08-05 2011-08-05
US61/515,435 2011-08-05
US201261612018P 2012-03-16 2012-03-16
US61/612,018 2012-03-16
PCT/US2012/049306 WO2013022694A1 (en) 2011-08-05 2012-08-02 Compositions and methods relating to nucleic acid nano-and micro-technology

Publications (1)

Publication Number Publication Date
KR20140054179A true KR20140054179A (ko) 2014-05-08

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KR1020147005854A Withdrawn KR20140054179A (ko) 2011-08-05 2012-08-02 핵산 나노- 및 마이크로-기술에 관한 조성물 및 방법

Country Status (9)

Country Link
US (1) US9796749B2 (https=)
EP (1) EP2739638B1 (https=)
JP (1) JP2014525921A (https=)
KR (1) KR20140054179A (https=)
CN (2) CN103889998A (https=)
AU (1) AU2012294724B2 (https=)
CA (1) CA2849072A1 (https=)
SG (1) SG10201606482TA (https=)
WO (1) WO2013022694A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2633071B1 (en) 2010-10-27 2016-10-12 President and Fellows of Harvard College Compositions of toehold primer duplexes and methods of use
US9796748B2 (en) 2011-05-02 2017-10-24 President And Fellows Of Harvard College Spatial sequestration of dynamic nucleic acid circuits
JP2014525921A (ja) 2011-08-05 2014-10-02 プレジデント アンド フェローズ オブ ハーバード カレッジ 核酸ナノテクノロジー及びマイクロテクノロジーに関する組成物及び方法
US9073962B2 (en) 2012-07-12 2015-07-07 Massachusetts Institute Of Technology Methods of serial assembly of DNA bricks into larger structures
WO2014018675A1 (en) 2012-07-24 2014-01-30 President And Fellows Of Harvard College Self-assembly of nucleic acid nanostructures
WO2014074597A1 (en) 2012-11-06 2014-05-15 President And Fellows Of Harvard College Compositions and methods relating to complex nucleic acid nanostructures
EP3594363A1 (en) 2014-04-23 2020-01-15 Children's Medical Center Corporation High-throughput structure determination using nucleic acid calipers
JP2017523594A (ja) 2014-05-22 2017-08-17 プレジデント アンド フェローズ オブ ハーバード カレッジ スケーラブルな核酸をベースにしたナノファブリケーション
US11639522B2 (en) 2015-01-30 2023-05-02 President And Fellows Of Harvard College Microscope-free imaging
WO2016144755A1 (en) 2015-03-07 2016-09-15 President And Fellows Of Harvard College Single-stranded dna nanostructures
CN105602949A (zh) * 2016-01-29 2016-05-25 同济大学 链间交换由支架dna达成的核酸结构及其合成方法
US11079388B2 (en) 2016-04-26 2021-08-03 Ultivue, Inc. Super-resolution immunofluorescence with diffraction-limited preview
CN109563539A (zh) 2016-06-15 2019-04-02 慕尼黑路德维希马克西米利安斯大学 使用dna纳米技术的单分子检测或定量
CN106517087B (zh) * 2017-01-06 2018-09-28 中国科学院苏州纳米技术与纳米仿生研究所 纳米颗粒螺旋和纳米棒组合结构及其构建方法
WO2018213372A1 (en) 2017-05-16 2018-11-22 President And Fellows Of Harvard College Nucleic acid-lined nanodiscs
WO2018218646A1 (zh) * 2017-06-02 2018-12-06 清华大学 Dna折纸单元分步组装法
EP3696275B1 (en) * 2017-10-11 2025-12-24 MGI Tech Co., Ltd. Method for improving loading and stability of nucleic acid on solid support
CN112189055B (zh) 2018-03-22 2024-07-19 哈佛学院院长及董事 用于分子认证的方法和组合物
EP3775196A4 (en) 2018-04-04 2021-12-22 Nautilus Biotechnology, Inc. METHOD FOR GENERATING NANOARRAYS AND MICROARRAYS
MA52750A (fr) 2018-06-05 2021-04-14 Univ Muenchen Tech Nouveau procédé de stabilisation de nanostructures d'acide nucléique
CA3135206A1 (en) 2019-04-29 2020-11-05 Pierre Indermuhle Methods and systems for integrated on-chip single-molecule detection
US10777381B1 (en) * 2019-08-08 2020-09-15 Ut-Battelle, Llc Beam controlled nano-robotic device
AU2021378290B2 (en) 2020-11-11 2025-10-30 Nautilus Subsidiary, Inc. Affinity reagents having enhanced binding and detection characteristics
IL305336B2 (en) 2021-03-11 2025-09-01 Nautilus Subsidiary Inc Systems and methods for preserving biomolecules
CA3227872A1 (en) 2021-09-09 2023-03-16 James Henry JOLY Characterization and localization of protein modifications
AU2022402132A1 (en) 2021-11-30 2024-05-30 Nautilus Subsidiary, Inc. Particle-based isolation of proteins and other analytes

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444650B1 (en) 1996-10-01 2002-09-03 Geron Corporation Antisense compositions for detecting and inhibiting telomerase reverse transcriptase
US6031098A (en) 1997-08-11 2000-02-29 California Institute Of Technology Detection and treatment of duplex polynucleotide damage
US6255469B1 (en) 1998-05-06 2001-07-03 New York University Periodic two and three dimensional nucleic acid structures
AU782880B2 (en) 1999-11-13 2005-09-08 Merck Patent Gmbh High order nucleic acid based structures
JP4340779B2 (ja) 2000-10-05 2009-10-07 独立行政法人理化学研究所 可変突出部位を含むオリゴヌクレオチドリンカー及び前記リンカーを用いたポリヌクレオチドライブラリーの調製方法
US7612184B2 (en) * 2002-02-22 2009-11-03 New York University Polynucleic acid nanomechanical device controlled by hybridization topology
JP4061401B2 (ja) * 2002-03-07 2008-03-19 国立大学法人九州大学 Dnaの自己組織化によるdnaナノケージ及びその製造方法、並びにそれを用いたdnaナノチューブ、分子キャリアー
WO2005024018A1 (ja) 2003-09-08 2005-03-17 Zoegene Corporation 核酸構築物およびその製造方法
CA2570108A1 (en) * 2004-06-10 2006-08-17 New York University Polygonal nanostructures of polynucleic acid multi-crossover molecules and assembly of lattices based on double crossover cohesion
WO2006017432A2 (en) * 2004-08-02 2006-02-16 New York University A polynucleotide nanomechanical device that acts as an artificial ribosome and translates dna signals into polymer assembly instructions
US7842793B2 (en) 2005-06-14 2010-11-30 The California Institute Of Technology Methods of making nucleic acid nanostructures
US7745594B2 (en) 2005-07-21 2010-06-29 California Institute Of Technology Nucleic acid-based logic circuits
WO2007012807A2 (en) 2005-07-27 2007-02-01 University Of Leeds Dna structures
WO2007103558A2 (en) 2006-03-09 2007-09-13 The Regents Of The University Of California Hybrid energy transfer for nucleic acid detection
CN101541961A (zh) * 2006-10-04 2009-09-23 布鲁克哈文科学协会 Dna指导的纳米颗粒组装体
US20080221315A1 (en) * 2006-12-07 2008-09-11 New York University Nucleic acid-based translation system and method for decoding nucleic acid encrypted message
WO2008130585A2 (en) 2007-04-17 2008-10-30 Dana-Farber Cancer Institute Wireframe nanostructures
WO2009093558A1 (ja) * 2008-01-22 2009-07-30 Tokyo Institute Of Technology 核酸構造体及びその核酸構造体を用いた核酸構造物、並びにその核酸構造物の作製方法
US20100291485A1 (en) 2008-09-14 2010-11-18 Troy Lapsys Nanoscale molecule synthesis
WO2010148085A1 (en) * 2009-06-16 2010-12-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Rna nanoparticles and methods of use
WO2011106057A2 (en) 2009-12-04 2011-09-01 Trustees Of Boston University Nanostructure biosensors and systems and methods of use thereof
US8877438B2 (en) 2010-07-20 2014-11-04 California Institute Of Technology Self-assembled polynucleotide structure
WO2012058638A2 (en) 2010-10-29 2012-05-03 President And Fellows Of Harvard College Nucleic acid nanostructure barcode probes
US20130316358A1 (en) 2011-01-31 2013-11-28 Yeda Research And Development Co. Ltd. Methods of diagnosing disease using overlap extension pcr
GB201111237D0 (en) 2011-06-30 2011-08-17 Isis Innovation Nanochip
JP2014525921A (ja) 2011-08-05 2014-10-02 プレジデント アンド フェローズ オブ ハーバード カレッジ 核酸ナノテクノロジー及びマイクロテクノロジーに関する組成物及び方法
WO2014018675A1 (en) 2012-07-24 2014-01-30 President And Fellows Of Harvard College Self-assembly of nucleic acid nanostructures
WO2014074597A1 (en) 2012-11-06 2014-05-15 President And Fellows Of Harvard College Compositions and methods relating to complex nucleic acid nanostructures
CN106459132A (zh) 2014-03-08 2017-02-22 哈佛学院院长及董事 由自组装的含顶点的固定角度核酸结构形成的核酸多面体

Also Published As

Publication number Publication date
EP2739638A1 (en) 2014-06-11
JP2014525921A (ja) 2014-10-02
WO2013022694A1 (en) 2013-02-14
CN107698640A (zh) 2018-02-16
AU2012294724A1 (en) 2014-03-06
US9796749B2 (en) 2017-10-24
SG10201606482TA (en) 2016-10-28
CN103889998A (zh) 2014-06-25
EP2739638B1 (en) 2017-10-04
CA2849072A1 (en) 2013-02-14
EP2739638A4 (en) 2015-04-08
US20140213778A1 (en) 2014-07-31
AU2012294724B2 (en) 2017-05-04

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Patent event date: 20140304

Patent event code: PA01051R01D

Comment text: International Patent Application

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