KR20130136988A - 지혈 장애를 치료하기 위한 인자 ii 및 피브리노겐 - Google Patents

지혈 장애를 치료하기 위한 인자 ii 및 피브리노겐 Download PDF

Info

Publication number
KR20130136988A
KR20130136988A KR1020137008520A KR20137008520A KR20130136988A KR 20130136988 A KR20130136988 A KR 20130136988A KR 1020137008520 A KR1020137008520 A KR 1020137008520A KR 20137008520 A KR20137008520 A KR 20137008520A KR 20130136988 A KR20130136988 A KR 20130136988A
Authority
KR
South Korea
Prior art keywords
fii
fibrinogen
coagulation
fviia
blood
Prior art date
Application number
KR1020137008520A
Other languages
English (en)
Korean (ko)
Inventor
안 로브그렌
케니 한손
Original Assignee
메디뮨 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44677879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20130136988(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 메디뮨 리미티드 filed Critical 메디뮨 리미티드
Publication of KR20130136988A publication Critical patent/KR20130136988A/ko

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
KR1020137008520A 2010-10-06 2011-09-19 지혈 장애를 치료하기 위한 인자 ii 및 피브리노겐 KR20130136988A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39022410P 2010-10-06 2010-10-06
US61/390,224 2010-10-06
PCT/EP2011/066241 WO2012045569A1 (en) 2010-10-06 2011-09-19 Factor ii and fibrinogen for treatment of haemostatic disorders

Publications (1)

Publication Number Publication Date
KR20130136988A true KR20130136988A (ko) 2013-12-13

Family

ID=44677879

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137008520A KR20130136988A (ko) 2010-10-06 2011-09-19 지혈 장애를 치료하기 위한 인자 ii 및 피브리노겐

Country Status (16)

Country Link
US (1) US9433664B2 (de)
EP (1) EP2624859B1 (de)
JP (1) JP6000259B2 (de)
KR (1) KR20130136988A (de)
CN (1) CN103221061A (de)
AU (1) AU2011313505B2 (de)
BR (1) BR112013008034A2 (de)
CA (1) CA2812888A1 (de)
DK (1) DK2624859T3 (de)
ES (1) ES2625153T3 (de)
HU (1) HUE033204T2 (de)
MX (1) MX343784B (de)
PL (1) PL2624859T3 (de)
RU (1) RU2606155C2 (de)
SG (2) SG10201508159SA (de)
WO (1) WO2012045569A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103221061A (zh) 2010-10-06 2013-07-24 米迪缪尼有限公司 用于治疗止血障碍的因子ii以及纤维蛋白原
IL230150A0 (en) 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One-component fibrin glue containing zymogens
DK3579857T3 (da) * 2017-02-09 2022-06-07 Csl Behring Gmbh Et blodkoagulationsfaktorerstatningsprodukt til anvendelse ved behandling eller profylakse af blødninger
CN116059431A (zh) * 2021-10-29 2023-05-05 丁琴琴 一种含凝血因子的双层止血敷料及其制备方法
WO2023220412A1 (en) * 2022-05-13 2023-11-16 Cedars-Sinai Medical Center Hemostatic monitor

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981002105A1 (en) * 1980-01-28 1981-08-06 Baxter Travenol Lab Therapeutic compositions & methods for manufacture and use
US4501731A (en) 1983-06-27 1985-02-26 Tishkoff Garson H Treatment of disparate bleeding disorders with factor X zymogen
DE4430204A1 (de) * 1994-08-26 1996-02-29 Behringwerke Ag Arzneimittel, welches als Gegenmittel für Blut-Antikoagulanzien geeignet ist und seine Verwendung
DK0796623T3 (da) * 1996-03-20 2005-08-01 Baxter Ag Farmaceutisk præparat til behandling af blodkoagulationslidelser
AT409334B (de) * 1997-09-19 2002-07-25 Immuno Ag Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren
US7094428B2 (en) 2000-06-16 2006-08-22 The University Of Medicine And Dentistry Of New Jersey Hemostatic compositions, devices and methods
US6825323B2 (en) 2001-01-10 2004-11-30 The United States Of America As Represented By The Secretary Of The Army Compositions for treatment of hemorrhaging with activated factor VIIa in combination with fibrinogen and methods of using same
IL156842A0 (en) 2001-02-05 2004-02-08 Novo Nordisk Healthcare Ag Combined use of factor vii polypeptides and factor ix polypeptides
US20060025336A1 (en) 2001-07-16 2006-02-02 Novo Nordisk A/S Pharmaceutical compositions comprising combinations of factor VII polypeptides and aprotinin polypeptides
HUP0400976A3 (en) 2001-07-20 2006-01-30 Novo Nordisk Healthcare Ag Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides
US20040101546A1 (en) 2002-11-26 2004-05-27 Gorman Anne Jessica Hemostatic wound dressing containing aldehyde-modified polysaccharide and hemostatic agents
AU2003303522B2 (en) 2002-12-31 2009-05-28 Marine Polymer Technologies, Inc. Hemostatic compositions and uses therefor
GB0324044D0 (en) 2003-10-14 2003-11-19 Astrazeneca Ab Protein
US7211559B2 (en) 2003-10-31 2007-05-01 University Of Maryland, Baltimore Factor VIII compositions and methods
EP1748781B1 (de) 2004-05-27 2012-12-19 Baxter International Inc. Verfahren zur behandlung von blutungsstörungen mittels sulfatierter polysaccharide
WO2006114105A2 (en) 2005-04-26 2006-11-02 Maxygen Holdings Ltd. Use of modified factor vii for treating bleeding
MX336958B (es) 2005-11-15 2016-02-05 Philadelphia Children Hospital Metodos y composiciones para modular la hemostasia.
CN101501216B (zh) * 2006-03-06 2013-10-02 胡玛基因公司 制备重组人凝血酶的方法
US20080014251A1 (en) 2006-07-14 2008-01-17 Advanced Vascular Dynamics Hemostatic compound and its use
US20090148502A1 (en) 2006-10-23 2009-06-11 Hemo Nanoscience, Llc Compositions and methods for treating lacerations, abrasions, avulsions, burns, ulcers, and cases of excessive bleeding
EP1935429A1 (de) 2006-12-22 2008-06-25 CSL Behring GmbH Synergistische therapeutische Anwendung von Prothrombin-Komplexkonzentraten mit FVIII-Konzentraten
WO2008121330A1 (en) 2007-03-30 2008-10-09 Thrombodyne, Inc. Methods of making concentrated fibrinogen containing compositions and associated systems for preparing fibrin glue
WO2008127702A2 (en) 2007-04-13 2008-10-23 Catalyst Biosciences, Inc. Modified factor vii polypetides and uses thereof
US8852558B2 (en) 2008-03-11 2014-10-07 Materials Modification, Inc. In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide and platinum catalyst
EP2337793A4 (de) 2008-10-08 2013-04-10 Thrombodyne Inc Verfahren zur herstellung von konzentriertem fibrinogen und plättchenhaltigen zusammensetzungen
CN103221061A (zh) 2010-10-06 2013-07-24 米迪缪尼有限公司 用于治疗止血障碍的因子ii以及纤维蛋白原

Also Published As

Publication number Publication date
RU2013120033A (ru) 2014-11-20
JP6000259B2 (ja) 2016-09-28
EP2624859B1 (de) 2017-03-01
WO2012045569A9 (en) 2016-01-07
AU2011313505A1 (en) 2013-04-11
MX343784B (es) 2016-11-23
WO2012045569A1 (en) 2012-04-12
HUE033204T2 (en) 2017-11-28
US20130280236A1 (en) 2013-10-24
SG10201508159SA (en) 2015-10-29
RU2606155C2 (ru) 2017-01-10
US9433664B2 (en) 2016-09-06
CN103221061A (zh) 2013-07-24
DK2624859T3 (en) 2017-06-06
SG188639A1 (en) 2013-05-31
AU2011313505B2 (en) 2015-09-17
MX2013003715A (es) 2013-09-26
BR112013008034A2 (pt) 2016-06-14
PL2624859T3 (pl) 2017-09-29
ES2625153T3 (es) 2017-07-18
EP2624859A1 (de) 2013-08-14
CA2812888A1 (en) 2012-04-12
JP2013538863A (ja) 2013-10-17

Similar Documents

Publication Publication Date Title
Solomon et al. Fibrin formation is more impaired than thrombin generation and platelets immediately following cardiac surgery
US20100279939A1 (en) Recombinant human fibrinogen for treatment of bleeding in trauma and platelet disorders
KR20130136988A (ko) 지혈 장애를 치료하기 위한 인자 ii 및 피브리노겐
US20090018082A1 (en) Use of Factor VIIa or Factor VIIa Equivalents for Treating Trauma
JP7227905B2 (ja) 出血の処置または予防における使用のための血液凝固因子代替製品
KR20120022717A (ko) 피브리노겐의 신규 용도
Chiba Serum transfusion as a hemostatic procedure
Parameswaran et al. The use of recombinant factor VIIa in gastrointestinal bleeding
Marcucci et al. 11 Hematologic Risk Assessment
MXPA06008483A (en) Use of factor viia factor for treating trauma
MXPA06008482A (es) Uso de reactor viia para el tratamiento de complicaciones posteriores por traumatismo

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application