KR20120127475A - 유체 여과를 위한 조립체와 방법 및 현미경 검사시의 사용 - Google Patents
유체 여과를 위한 조립체와 방법 및 현미경 검사시의 사용 Download PDFInfo
- Publication number
- KR20120127475A KR20120127475A KR1020127022389A KR20127022389A KR20120127475A KR 20120127475 A KR20120127475 A KR 20120127475A KR 1020127022389 A KR1020127022389 A KR 1020127022389A KR 20127022389 A KR20127022389 A KR 20127022389A KR 20120127475 A KR20120127475 A KR 20120127475A
- Authority
- KR
- South Korea
- Prior art keywords
- support
- filter membrane
- carrier
- filtration
- fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000001914 filtration Methods 0.000 title claims abstract description 67
- 238000000034 method Methods 0.000 title claims abstract description 18
- 238000000386 microscopy Methods 0.000 title claims description 9
- 239000007788 liquid Substances 0.000 title description 2
- 239000012528 membrane Substances 0.000 claims abstract description 111
- 239000012530 fluid Substances 0.000 claims abstract description 68
- 210000004369 blood Anatomy 0.000 claims abstract description 12
- 239000008280 blood Substances 0.000 claims abstract description 12
- 210000004027 cell Anatomy 0.000 claims description 16
- 238000004891 communication Methods 0.000 claims description 7
- 210000000265 leukocyte Anatomy 0.000 claims description 6
- 239000004033 plastic Substances 0.000 claims description 6
- 229920003023 plastic Polymers 0.000 claims description 6
- 238000000799 fluorescence microscopy Methods 0.000 claims description 5
- 238000000399 optical microscopy Methods 0.000 claims description 5
- 239000000919 ceramic Substances 0.000 claims description 4
- 210000003743 erythrocyte Anatomy 0.000 claims description 4
- 238000005530 etching Methods 0.000 claims description 4
- 239000000706 filtrate Substances 0.000 claims description 4
- 239000011521 glass Substances 0.000 claims description 4
- 239000004417 polycarbonate Substances 0.000 claims description 4
- 229920000515 polycarbonate Polymers 0.000 claims description 4
- 229920006289 polycarbonate film Polymers 0.000 claims description 4
- 206010028980 Neoplasm Diseases 0.000 claims description 3
- 201000011510 cancer Diseases 0.000 claims description 3
- 239000008004 cell lysis buffer Substances 0.000 claims description 3
- 230000009089 cytolysis Effects 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 abstract description 12
- 239000012466 permeate Substances 0.000 abstract 1
- 239000010408 film Substances 0.000 description 8
- 238000003384 imaging method Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000001419 dependent effect Effects 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 239000000969 carrier Substances 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 108020004414 DNA Proteins 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 230000032823 cell division Effects 0.000 description 2
- 230000006037 cell lysis Effects 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
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- 238000003754 machining Methods 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 230000010076 replication Effects 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000008093 supporting effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 description 1
- 108020004635 Complementary DNA Proteins 0.000 description 1
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- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000010804 cDNA synthesis Methods 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 239000006059 cover glass Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000018732 detection of tumor cell Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
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- 238000010820 immunofluorescence microscopy Methods 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000002101 lytic effect Effects 0.000 description 1
- 229960000907 methylthioninium chloride Drugs 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
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- 102000004169 proteins and genes Human genes 0.000 description 1
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Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/10—Supported membranes; Membrane supports
- B01D69/107—Organic support material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0822—Slides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
- G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Sampling And Sample Adjustment (AREA)
- Filtering Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102010001322A DE102010001322A1 (de) | 2010-01-28 | 2010-01-28 | Anordnung und Verfahren zur Filtration einer Flüssigkeit und Verwendung in der Mikroskopie |
| DE102010001322.6 | 2010-01-28 | ||
| PCT/EP2011/051064 WO2011092201A1 (de) | 2010-01-28 | 2011-01-26 | Anordnung und verfahren zur filtration einer flüssigkeit und verwendung in der mikroskopie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20120127475A true KR20120127475A (ko) | 2012-11-21 |
Family
ID=43901344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127022389A Abandoned KR20120127475A (ko) | 2010-01-28 | 2011-01-26 | 유체 여과를 위한 조립체와 방법 및 현미경 검사시의 사용 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20120315664A1 (enExample) |
| EP (1) | EP2528686A1 (enExample) |
| JP (1) | JP2013517932A (enExample) |
| KR (1) | KR20120127475A (enExample) |
| CN (1) | CN102791378A (enExample) |
| DE (1) | DE102010001322A1 (enExample) |
| WO (1) | WO2011092201A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011076238A1 (de) * | 2011-05-20 | 2012-11-22 | Siemens Ag | Anordnung und Verfahren zur optischen Analyse und spezifischen Isolierung von biologischen Proben |
| DE102011083215A1 (de) | 2011-09-22 | 2013-03-28 | Siemens Aktiengesellschaft | Probenträger und Verfahren zur mikroskopischen Untersuchung biologischer Proben |
| ES2751454T3 (es) | 2013-05-17 | 2020-03-31 | Siemens Healthcare Diagnostics Inc | Liberación y recogida de partículas |
| EP3011304B8 (en) | 2013-06-19 | 2018-05-16 | Brightwake Limited | Cell collecting device |
| EP3361254B1 (en) | 2013-12-18 | 2019-10-23 | Siemens Healthcare Diagnostics Inc. | Detection of endothelial disease |
| US9968738B2 (en) | 2014-03-24 | 2018-05-15 | Fenwal, Inc. | Biological fluid filters with molded frame and methods for making such filters |
| US9782707B2 (en) | 2014-03-24 | 2017-10-10 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
| US10376627B2 (en) | 2014-03-24 | 2019-08-13 | Fenwal, Inc. | Flexible biological fluid filters |
| US10159778B2 (en) | 2014-03-24 | 2018-12-25 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
| US9796166B2 (en) | 2014-03-24 | 2017-10-24 | Fenwal, Inc. | Flexible biological fluid filters |
| WO2017143310A1 (en) * | 2016-02-18 | 2017-08-24 | Siemens Healthcare Diagnostics Inc. | Rack for a filtration device |
| US20200188906A1 (en) * | 2016-02-18 | 2020-06-18 | Siemens Healthcare Diagnostics Inc. | Container for a filtration assembly |
| EP3417267A4 (en) * | 2016-02-18 | 2019-03-27 | Siemens Healthcare Diagnostics Inc. | GAS IN / OUT ADAPTER SYSTEM FOR A FILTRATION DEVICE |
| CN105717310A (zh) * | 2016-04-15 | 2016-06-29 | 肖乐义 | 一种检测白细胞中结核分枝杆菌的免疫荧光染色方法及试剂盒 |
| CN105759038A (zh) * | 2016-04-15 | 2016-07-13 | 肖乐义 | 一种检测生物样品中结核分枝杆菌的免疫检测方法及试剂盒 |
| EP3496842B1 (en) | 2016-08-11 | 2022-04-27 | Siemens Healthcare Diagnostics Inc. | Heating device for a filtration assembly |
| US20180283998A1 (en) * | 2017-04-01 | 2018-10-04 | Mike Joseph Pugia | Methods and apparatus for removal of small volume from a filtration device |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1102497A (en) * | 1965-05-11 | 1968-02-07 | Douglas Dean Fairey | Filter for liquids |
| US3386585A (en) * | 1965-11-09 | 1968-06-04 | Millipore Corp | Filter holder and support |
| US3731806A (en) * | 1971-03-01 | 1973-05-08 | Pelam Inc | Specimen analysis device |
| US4124449A (en) * | 1977-02-07 | 1978-11-07 | Barta Kent S | Method and apparatus for bacterial microscopy |
| FR2638240B1 (fr) * | 1988-10-21 | 1991-10-18 | Biocom Sa | Platine pour l'analyse rapide et indexee sous microscope de filtres et d'autres supports porteurs d'echantillons multiples et procede d'analyse de ces echantillons utilisant cette platine |
| US5269917A (en) * | 1992-02-28 | 1993-12-14 | Millipore Corporation | Filtration apparatus having stress relief groove |
| US5454951A (en) * | 1993-03-05 | 1995-10-03 | Minnesota Mining And Manufacturing Company | Separation-science medium support plate |
| NO180658C (no) * | 1994-03-10 | 1997-05-21 | Oeystein Fodstad | Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner |
| US5603900A (en) * | 1995-05-19 | 1997-02-18 | Millipore Investment Holdings Limited | Vacuum filter device |
| US5807481A (en) * | 1995-12-21 | 1998-09-15 | Parker-Hannifin Corporation | Oil filter assembly with support for removable planar filter |
| US6734012B2 (en) * | 2000-07-05 | 2004-05-11 | Cuno Incorporated | Low fluorescence nylon/glass composites for micro-analytical diagnostic applications |
| US6750039B1 (en) * | 2001-03-21 | 2004-06-15 | Boston Probes, Inc. | Filtration apparatus and method for the separation of microscopic entities from a fluid |
| US20050164188A1 (en) * | 2002-01-24 | 2005-07-28 | Jeffrey Kane | Analysis device |
| US20060108287A1 (en) * | 2004-09-21 | 2006-05-25 | Arnold Todd E | Discrete zoned microporous nylon coated glass platform for use in microwell plates and methods of making and using same |
| US7507578B2 (en) * | 2004-10-21 | 2009-03-24 | Cytyc Corporation | Reduced aperture biological specimen collection and transfer device |
| DE202006009728U1 (de) * | 2005-07-12 | 2006-11-16 | Sartorius Ag | Mikroarray-Anordnung, die eine mikroporöse Membran und eine spezifische Inkubationskammeranordnung umfaßt |
| GB0614297D0 (en) * | 2006-07-19 | 2006-08-30 | Shaw Water Engineering Ltd | Apparatus, system and method for detecting particles |
| WO2009134509A2 (en) * | 2008-02-15 | 2009-11-05 | 3M Innovative Properties Company | Sample acquisition device |
-
2010
- 2010-01-28 DE DE102010001322A patent/DE102010001322A1/de not_active Withdrawn
-
2011
- 2011-01-26 KR KR1020127022389A patent/KR20120127475A/ko not_active Abandoned
- 2011-01-26 EP EP11701813A patent/EP2528686A1/de not_active Withdrawn
- 2011-01-26 CN CN2011800135465A patent/CN102791378A/zh active Pending
- 2011-01-26 JP JP2012550426A patent/JP2013517932A/ja not_active Ceased
- 2011-01-26 US US13/575,651 patent/US20120315664A1/en not_active Abandoned
- 2011-01-26 WO PCT/EP2011/051064 patent/WO2011092201A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011092201A1 (de) | 2011-08-04 |
| JP2013517932A (ja) | 2013-05-20 |
| US20120315664A1 (en) | 2012-12-13 |
| DE102010001322A1 (de) | 2011-08-18 |
| EP2528686A1 (de) | 2012-12-05 |
| CN102791378A (zh) | 2012-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20120827 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20120828 Comment text: Request for Examination of Application |
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| PG1501 | Laying open of application | ||
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20130905 Patent event code: PE09021S01D |
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| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 20140325 |
|
| NORF | Unpaid initial registration fee | ||
| PC1904 | Unpaid initial registration fee |