KR20120121303A - Anthocyanine Water Hair Care - Google Patents

Anthocyanine Water Hair Care Download PDF

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Publication number
KR20120121303A
KR20120121303A KR1020110039204A KR20110039204A KR20120121303A KR 20120121303 A KR20120121303 A KR 20120121303A KR 1020110039204 A KR1020110039204 A KR 1020110039204A KR 20110039204 A KR20110039204 A KR 20110039204A KR 20120121303 A KR20120121303 A KR 20120121303A
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Prior art keywords
hair
anthocyanin
water
hair loss
cosmetic composition
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KR1020110039204A
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Korean (ko)
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노효만
이영수
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노효만
이영수
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Priority to KR1020110039204A priority Critical patent/KR20120121303A/en
Publication of KR20120121303A publication Critical patent/KR20120121303A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/002Preparations for repairing the hair, e.g. hair cure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof

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  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a hair cosmetic composition for preventing hair loss containing anthocyanin water extracted from anthocyanin, a natural antioxidant, by extracting an anthocyanin-rich cornice husk nano-crush by a low temperature elution method. Hair loss prevention hair cosmetic composition according to the present invention is very excellent in the effect of inhibiting hair loss by acting on all and the scalp to nourish and restore the healthy hair root and scalp damaged by the oxidation reaction.

Description

Hair loss prevention hair composition containing anthocyanin water {Anthocyanine Water Hair Care}

The present invention relates to an anti-hair loss hair cosmetic composition containing anthocyanin water, and more particularly, anthocyanin obtained by extracting anthocyanin, which is a natural antioxidant, by extracting a deciduous bean hull nanoparticle containing rich anthocyanin by low temperature elution method. It relates to a hair loss preventing hair composition for containing water as an active ingredient. Hair loss prevention hair cosmetic composition according to the present invention is very excellent in the effect of inhibiting hair loss by acting on all and the scalp to nourish and restore the healthy hair root and scalp damaged by the oxidation reaction.

In modern society that emphasizes beauty, many people, regardless of age or gender, use hair dye and perm to satisfy their individual expression needs. However, some of the sensitive scalp are treated by chemical treatment such as dyeing and perm. Stimulation and inflammation, such as itching and stinging, can also be caused. This irritation phenomenon and inflammation leads to environmental hair loss, and various studies are being actively conducted to prevent hair loss and promote hair growth of men or women who are suffering from severe mental pain.

Therefore, it is urgent to develop a composition that is effective in strengthening the hair root, preventing hair loss, and promoting hair growth, with the effect of alleviating scalp irritation and light inflammation caused by the use of various hair dyes and permants.

Hair and scalp are part of the body, and as they age, skin and aging appear as aging, and as aging progresses, various changes and problems appear. In recent years, attempts have been made to nourish hair roots other than washing and antistatic in hair cosmetics such as shampoos, conditioners and tonics, and to prevent hair loss and aging of the scalp. . In general, the herbal extract extracted from hydrothermal is used to enhance this effect, and these ingredients are insufficient to restore hair damage caused by destabilization of the active ingredient, which is effective in providing nutrition to weakened and aged hair and scalp effectively. There is a limit.

Accordingly, the present inventors have solved the above problems and provide a hair cosmetic composition for hair loss prevention containing stabilizing the anthocyanin contained in a large amount of eyelids, and as a result, the anthocyanin water eluted at low temperature by nano-crushing the bean shells. It was found that the hair cosmetic material composition containing a large amount provides an excellent hair loss prevention effect and completed the present invention.

Therefore, it is an object of the present invention to provide a hair cosmetic composition having an excellent hair loss prevention effect by containing a large amount of anthocyanin water extracted by low temperature elution by grinding the mouse skin with nanoparticles.

The hair cosmetic composition prepared according to the present invention, unlike the formulation containing the conventional hot water extract, contains the anthocyanin water extracted by low temperature elution by crushing the rat's skin, which is the main water-soluble efficacy ingredient of the rat's skin. It can stably contain large amount of anthocyanin and prevent hair damage of hair root, scalp and hair caused by oxidation which causes hair loss, nourish hair root, and restore damaged hair root and scalp to healthy and excellent hair loss prevention effect.

The present invention provides a hair cosmetic composition for preventing hair loss, containing anthocyanin water extracted from the mouse skin.

Hereinafter, the present invention will be described in more detail.

Rat eye bean used as an active ingredient in the present invention is known to be effective in gray hair or hair loss because it contains a component that facilitates blood circulation of peripheral blood vessels. That is, it contains a lot of unsaturated fatty acid that inhibits 5-reductase, which causes hair loss, and prevents cholesterol from accumulating in blood vessels and cleans blood vessels like saponins. The unsaturated fatty acid has been reported by the University of Chicago to find that essential fatty acids found in vegetable oils, gamma linoleic acid, alpha linoleic acid and oleic acid, inhibit both types 1 and 2. In addition, it is said that it belongs to water in Yin-Yang five fives, makes the function of kidney and bladder smooth, and detoxifies specially. Arginine, a nutrient essential for hair growth, is a metabolic precursor of Nitric Oxide that promotes hair growth and prevents the side effects of sexual function caused by anti-androgens and is essential for hair growth. Cysteine has been shown to be effective in preventing hair loss. In addition, according to the five-point theory, the color of the food is closely related to each function of our body, of which black food is closely related to the god (intestine). In addition to the urinary and reproductive organs of the body and the function of maintaining the vitality of the whole body refers to the organs. Especially in Chinese medicine, Shin is known to be involved in hair. Black is a very special color in nature that absorbs the sun and heats itself. Black food with this property has a far-infrared effect that warms the body from the inside when it enters our body. The most notable functionalities include antioxidant activity that removes free radicals. Anthocyanins, which are representative antioxidants, are excellent for suppressing blood pressure rise, improving liver function, improving eyesight, inhibiting absorption of excess lipids that cause obesity, and skin care. Efficacy has been shown in recent studies.

In the present invention, unlike the formulations containing hot water extract through heating, the rat eye is crushed into nanoparticles and extracted at low temperature, so that the mouse eye is stably contained an anthocyanin water containing a large amount of water-soluble active ingredient in the bean shell. It contains in a composition.

It will be described in more detail the manufacturing method of the anthocyanin water used in the present invention.

Buy domestic rats soybeans and dry them in a dryer (Korean powder HKV-500) to remove impurities and dust through the air shower and to ease peeling. The dried rat eye keeps the moisture content of about 3 ~ 4% and then separates the shell separately using a peeler (produce). The thickness of the shell is adjusted to 5.5 ~ 7.0% of the total weight. Only the separated shells are processed to a particle size of 500 ~ 1,000 mesh using a Micro Air Jet Mill. The processed rat bean powder is again nano-crushed into particles of 200-1,000 nm using a nano grinder (manufactured by Korean powder). The nano-sized pulverized soybean hull powder has a large surface area per particle and can extract a large amount of anthocyanin in a short time during low temperature elution. Anthocyanin water can be prepared by the low-temperature elution method known in the art as the soybean hull-shell nano-crushed thus produced, and the method is not particularly limited. In general, the mouse eye can be obtained by adding purified water to the soybean shell nano-crushed water eluted for 12 hours or more at room temperature.

Anthocyanin water of the present invention is contained in 1.0 to 50.0% by weight, more preferably 5.0 to 30.0% by weight relative to the total weight of the hair cosmetic composition. If the content is less than 1.0% by weight it is difficult to expect the efficacy, if it exceeds 50.0% by weight may cause problems in formulation stability.

There is no particular limitation in formulating the hair cosmetic composition of the present invention, but hair shampoo, hair rinse, hair tonic, hair nutrient lotion, hair essence, hair serum, hair ampoule, hair treatment, hair conditioner, hair lotion, hair It may be a cosmetic composition having a formulation such as a hair dye, hair perming agent and the like.

In addition, in each formulation, components other than anthocyanin water can be suitably selected and mix | blended by a person skilled in the art according to the kind of other external preparations, or the purpose of use.

Hereinafter, the present invention will be described in more detail with reference to Examples and Test Examples, but the scope of the present invention is not limited only to these examples.

EXAMPLE 1 AND COMPARATIVE EXAMPLES 1-4

In order to evaluate the hair loss prevention effect of the anthocyanin water prepared by low temperature elution of the mouse skin nano-crush, Example 1 and Comparative Examples 1 to 4 were prepared. Example 1 was prepared by putting 25 g of mouse bean nanoparticles in 1,000 ml of purified water and then eluting at room temperature (18-25) for 12 hours, filtration twice with 0.45 filter, and once again with 0.2 filter.

Comparative Example 1 is purified water containing no corn crushed nanoparticles, Comparative Example 2 is 25g of uncrushed mouse skin in 1,000ml of purified water and heated (90-100) for 1 hour, and twice with 0.45 filter, Prepared by filtration once with 0.2 filter.

Comparative Example 3 was prepared by eluting 25 g of uncrushed rat bean shells in 1,000 ml of purified water at low temperature for 12 hours at room temperature (18-25) and filtration twice with 0.45 filter and once with 0.2 filter.

Comparative Example 4 was prepared by putting 25 g of the mouse hull bean nano grinding into 1,000 ml of purified water, heating (90-100) for 1 hour, filtering twice with 0.45 filter, and once with 0.2 filter.

Table 1

Figure pat00001

Test Example 1 Anthocyanin Content Analysis

As shown in Table 1, to analyze the content of the anthocyanin contained in Comparative Example 1, Comparative Example 2, Comparative Example 3, Comparative Example 4, Example 1 was analyzed using HPLC (Agilent 1100).

 HPLC analysis conditions

  Detector: UV520nm

  Column: Eclipse C18 * BB (Agilent)

  Column Temperature: 25

  Injection Volumn: 20uL

  Mobile Phase: A-5% formic acid, B-Methanol + 5% formic acid

  Gradient: 1min-5% B

             29min-40% B

             10min-100% B

Flow Rate: 1.0m / min

Table 2

Figure pat00002

Comparative Example 2 HPLC Analysis

Figure pat00003

Comparative Example 3 HPLC Analysis

Figure pat00004

Comparative Example 4 HPLC Analysis

Figure pat00005

Example 1 HPLC Analysis

Figure pat00006

As can be seen from Table 2 and the HPLC analysis contents 1, 2, 3, and 4. As compared with Comparative Example 2 and Comparative Example 4, or Comparative Example 3 and Example 1, the nano-bean hulls were not crushed. It can be seen that the anthocyanin was contained during the heat extraction or low temperature elution while pulverized into particles, and the content of anthocyanin during low temperature elution was higher than that in the heat extraction as in Comparative Example 2 and Comparative Example 3, or Comparative Example 4 and Example 1. Found to be high. This suggests that in order to obtain anthocyanin with anthocyanin water having a stable high concentration of anthocyanin, the rat's eye shell should be prepared by low temperature elution with the nanoparticles.

Reference Example Preparation of Shampoo Formulations

Shampoo of Comparative Example 5, Example 2 was prepared by a conventional shampoo preparation method according to the formulation of Table 3 as a hair cosmetic composition.

TABLE 3

Figure pat00007

Example 2 was prepared by containing the anthocyanin water eluted at low temperature with the mouse skin soybean shell nano Example 1, Comparative Example 5 was prepared without the addition of anthocyanin water.

Test Example 2 Hair Loss Prevention Effect Test

A 20-year-old female alopecia with alopecia was selected for 10 out of 20 subjects with comparative example 5 and the remaining 10 with example 2 were given shampoo every day for 4 weeks. The results were evaluated in a way of answering the 5-point scale (the higher the score, the better the result), and the results are shown in Table 4, where the evaluation criteria are significant when visualizing hair loss, subjective symptoms, and hair loss at trituration. The overall score was 5 points, 4 points for moderate, 3 points for mild, 2 points for discomfort, and 1 point for alopecia worsening.

Table 4

Figure pat00008

The results of the reviews in Table 4 show that the use of Example 2 containing anthocyanin water exhibits better hair loss prevention effect than that of Comparative Example 5 containing no anthocyanin water.

Claims (5)


Hair loss prevention hair composition containing anthocyanin water as an active ingredient

The hair cosmetic composition for preventing hair loss of claim 1, wherein the anthocyanin water is extracted from rat bean nanocrack.

The anti-hair loss hair cosmetic composition according to claim 1, wherein the anthocyanin water is extracted by a low-temperature elution method by adding soybean hull nano-crushed water to purified water.

The hair cosmetic composition for preventing hair loss of claim 1, wherein the anthocyanin water is contained in an amount of 1.0 to 50% by weight based on the total weight of the composition.

The method of claim 1, wherein the anthocyanin water is formulated as a hair shampoo, hair rinse, hair tonic, hair nourishing cosmetics, hair essence, hair serum, hair ampoule, hair treatment, hair conditioner, hair lotion, hair dye, hair perm Hair loss prevention hair composition for preventing hair loss, characterized in that
KR1020110039204A 2011-04-26 2011-04-26 Anthocyanine Water Hair Care KR20120121303A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019030955A1 (en) * 2017-08-09 2019-02-14 有限会社オービット Black raspberry extract, hair loss suppressing agent including black raspberry extract, food and beverage, production method for black raspberry extract, and hair loss suppression method using black raspberry extract
WO2019078646A3 (en) * 2017-10-20 2019-06-06 (주)아모레퍼시픽 Composition, containing extract from bean culture, for prevention of hair loss or promotion of hair growth and method for preparing same
CN110200837A (en) * 2019-06-20 2019-09-06 华熙生物科技股份有限公司 A kind of hair growth composition

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019030955A1 (en) * 2017-08-09 2019-02-14 有限会社オービット Black raspberry extract, hair loss suppressing agent including black raspberry extract, food and beverage, production method for black raspberry extract, and hair loss suppression method using black raspberry extract
WO2019078646A3 (en) * 2017-10-20 2019-06-06 (주)아모레퍼시픽 Composition, containing extract from bean culture, for prevention of hair loss or promotion of hair growth and method for preparing same
CN111246868A (en) * 2017-10-20 2020-06-05 株式会社爱茉莉太平洋 Composition for preventing hair loss or promoting hair growth comprising extract of cultured tissue of beans and preparation method thereof
CN110200837A (en) * 2019-06-20 2019-09-06 华熙生物科技股份有限公司 A kind of hair growth composition
CN110200837B (en) * 2019-06-20 2022-04-29 华熙生物科技股份有限公司 Hair growth composition

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