KR20120114224A - Ｉｋｋ 엡실론 및/또는 ｔｂｋ１의 억제제로서의 아미노-피리미딘 화합물 - Google Patents

Ｉｋｋ 엡실론 및/또는 ｔｂｋ１의 억제제로서의 아미노-피리미딘 화합물 Download PDF

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KR20120114224A
KR20120114224A KR1020127012283A KR20127012283A KR20120114224A KR 20120114224 A KR20120114224 A KR 20120114224A KR 1020127012283 A KR1020127012283 A KR 1020127012283A KR 20127012283 A KR20127012283 A KR 20127012283A KR 20120114224 A KR20120114224 A KR 20120114224A
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amino
pyrimidin
phenyl
benzonitrile
yloxy
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Korean (ko)
Inventor
리안 홀컴
가즈유키 스즈키
로버트 제이. 홀터
폴 알. 세바하
도날드 에이. 맥러드
마크 디. 쉔데로비치
크레이그 엠. 예이거
매튜 그레고리 부르사비치
아샨타이 제이. 윤가이
버트 리처즈
폴 엘. 바텔
다니엘 에이. 베트슈타인
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마이렉시스 인코포레이티드
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020127012283A 2009-10-12 2010-10-12 Ｉｋｋ 엡실론 및/또는 ｔｂｋ１의 억제제로서의 아미노-피리미딘 화합물 Withdrawn KR20120114224A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25084209P 2009-10-12 2009-10-12
US61/250,842 2009-10-12
US32524510P 2010-04-16 2010-04-16
US61/325,245 2010-04-16

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KR20120114224A true KR20120114224A (ko) 2012-10-16

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KR1020127012283A Withdrawn KR20120114224A (ko) 2009-10-12 2010-10-12 Ｉｋｋ 엡실론 및/또는 ｔｂｋ１의 억제제로서의 아미노-피리미딘 화합물

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US (2) US20120238540A1 (https=)
EP (1) EP2488503A1 (https=)
JP (1) JP2013507449A (https=)
KR (1) KR20120114224A (https=)
CN (1) CN102791697A (https=)
AU (1) AU2010306927A1 (https=)
BR (1) BR112012008677A2 (https=)
CA (1) CA2777762A1 (https=)
MX (1) MX2012004313A (https=)
NZ (1) NZ599826A (https=)
WO (1) WO2011046970A1 (https=)

Cited By (1)

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KR20170049609A (ko) * 2014-09-26 2017-05-10 길리애드 사이언시즈, 인코포레이티드 Tank-결합 키나제 억제제 화합물로서 유용한 아미노트리아진 유도체

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WO2012142329A1 (en) * 2011-04-12 2012-10-18 Myrexis, Inc. Compositions and therapeutic uses of ikk-related kinase epsilon and tankbinding kinase 1 inhibitors
CN103476759B (zh) 2011-04-19 2016-03-16 拜耳知识产权有限责任公司 取代的4-芳基-n-苯基-1,3,5-三嗪-2-胺
TW201636330A (zh) 2011-05-24 2016-10-16 拜耳知識產權公司 含有硫醯亞胺基團之４－芳基－ｎ－苯基－１，３，５－三氮雜苯－２－胺
GB201114051D0 (en) 2011-08-15 2011-09-28 Domainex Ltd Compounds and their uses
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EP2755948B1 (en) 2011-09-16 2016-05-25 Bayer Intellectual Property GmbH Disubstituted 5-fluoro pyrimidine derivatives containing a sulfoximine group
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HRP20161578T1 (hr) 2012-02-09 2016-12-30 Merck Patent Gmbh Derivati furo[3, 2-b]piridina kao inhibitori tbk1 i ikk
WO2013175415A1 (en) * 2012-05-23 2013-11-28 Piramal Enterprises Limited Substituted pyrimidine compounds and uses thereof
EP2904119B1 (en) * 2012-10-02 2020-06-17 The General Hospital Corporation d/b/a Massachusetts General Hospital Methods relating to dna-sensing pathway related conditions
HK1209414A1 (en) 2012-10-18 2016-04-01 Bayer Pharma Aktiengesellschaft 5-fluoro-n-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group
CN105102434A (zh) 2012-10-18 2015-11-25 拜耳药业股份公司 含砜基团的4-(邻)-氟苯基-5-氟嘧啶-2-基胺
TW201418243A (zh) 2012-11-15 2014-05-16 Bayer Pharma AG 含有磺醯亞胺基團之ｎ－（吡啶－２－基）嘧啶－４－胺衍生物
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