KR20120113219A - (메틸술포닐)에틸 벤젠 이소인돌린 유도체 및 그의 치료 용도 - Google Patents
(메틸술포닐)에틸 벤젠 이소인돌린 유도체 및 그의 치료 용도 Download PDFInfo
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- KR20120113219A KR20120113219A KR1020127016076A KR20127016076A KR20120113219A KR 20120113219 A KR20120113219 A KR 20120113219A KR 1020127016076 A KR1020127016076 A KR 1020127016076A KR 20127016076 A KR20127016076 A KR 20127016076A KR 20120113219 A KR20120113219 A KR 20120113219A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
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- Health & Medical Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
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| US28935609P | 2009-12-22 | 2009-12-22 | |
| US61/289,356 | 2009-12-22 |
Publications (1)
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| KR20120113219A true KR20120113219A (ko) | 2012-10-12 |
Family
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Family Applications (1)
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| KR1020127016076A Withdrawn KR20120113219A (ko) | 2009-12-22 | 2010-12-21 | (메틸술포닐)에틸 벤젠 이소인돌린 유도체 및 그의 치료 용도 |
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| US (1) | US8716252B2 (OSRAM) |
| EP (1) | EP2516395A1 (OSRAM) |
| JP (1) | JP5760008B2 (OSRAM) |
| KR (1) | KR20120113219A (OSRAM) |
| CN (1) | CN102770412A (OSRAM) |
| AU (1) | AU2010333767A1 (OSRAM) |
| BR (1) | BR112012015129A2 (OSRAM) |
| CA (1) | CA2783616A1 (OSRAM) |
| CL (1) | CL2012001671A1 (OSRAM) |
| CO (1) | CO6640204A2 (OSRAM) |
| CR (1) | CR20120335A (OSRAM) |
| EC (1) | ECSP12011987A (OSRAM) |
| MX (1) | MX2012007217A (OSRAM) |
| PH (1) | PH12012501237A1 (OSRAM) |
| RU (1) | RU2012131164A (OSRAM) |
| SG (1) | SG181891A1 (OSRAM) |
| WO (1) | WO2011079091A1 (OSRAM) |
| ZA (1) | ZA201203944B (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020036386A1 (ko) * | 2018-08-16 | 2020-02-20 | 한국화학연구원 | 이소인돌린-1온 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 |
Families Citing this family (7)
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| AU2012236655B2 (en) | 2011-03-28 | 2016-09-22 | Deuterx, Llc, | 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds |
| CA2935495C (en) | 2013-01-14 | 2021-04-20 | Deuterx, Llc | 3-(5-substituted-4-oxoquinazolin-3(4h)-yl)-3-deutero-piperidine-2,6-dione derivatives |
| US9290475B2 (en) | 2013-03-14 | 2016-03-22 | Deuterx, Llc | 3-(substituted-4-oxoquinazolin-3(4H)-yl)-3-deutero-piperidine-2,6-dione derivatives and compositions comprising and methods of using the same |
| US9809603B1 (en) | 2015-08-18 | 2017-11-07 | Deuterx, Llc | Deuterium-enriched isoindolinonyl-piperidinonyl conjugates and oxoquinazolin-3(4H)-yl-piperidinonyl conjugates and methods of treating medical disorders using same |
| MY195528A (en) | 2016-03-17 | 2023-01-30 | Hoffmann La Roche | 5-Ethyl-4-Methyl-Pyrazole-3-Carboxamide Derivative Having Activity as Agonist of Taar |
| US20190008837A1 (en) * | 2016-12-15 | 2019-01-10 | University Of Utah Research Foundation | Ophthalmic compositions and associated methods |
| AU2020353984B2 (en) | 2019-09-27 | 2025-09-25 | Takeda Pharmaceutical Company Limited | 2-isoindol-1,3,4-oxadiazole derivatives useful as HDAC6 inhibitors |
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| JP2007533761A (ja) | 2004-04-23 | 2007-11-22 | セルジーン・コーポレーション | 肺高血圧症を治療し管理するための、免疫調節性化合物の使用方法及び免疫調節性化合物を含む組成物 |
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| CN101111234A (zh) | 2004-12-01 | 2008-01-23 | 细胞基因公司 | 包含免疫调节化合物的组合物及其治疗免疫缺陷疾病的用途 |
| JP2009507030A (ja) | 2005-09-01 | 2009-02-19 | セルジーン・コーポレーション | ワクチン及び抗感染症療法のための免疫調節性化合物の免疫学的使用 |
| WO2008044027A2 (en) * | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical compounds having hsp90 inhibitory or modulating activity |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020036386A1 (ko) * | 2018-08-16 | 2020-02-20 | 한국화학연구원 | 이소인돌린-1온 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 |
| KR20200020607A (ko) * | 2018-08-16 | 2020-02-26 | 한국화학연구원 | 이소인돌린-1온 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 |
| CN112839937A (zh) * | 2018-08-16 | 2021-05-25 | 韩国化学研究院 | 异吲哚啉-1-酮衍生物、其制备方法、和包含其作为有效组分的用于预防或治疗癌症的药物组合物 |
| CN112839937B (zh) * | 2018-08-16 | 2023-08-22 | 韩国化学研究院 | 异吲哚啉-1-酮衍生物、其制备方法及其用途 |
| US11976059B2 (en) | 2018-08-16 | 2024-05-07 | Korea Research Institute Of Chemical Technology | Isoindolin-1-on derivative, method for preparing same, and pharmaceutical composition comprising same as effective component for preventing or treating cancer |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5760008B2 (ja) | 2015-08-05 |
| ECSP12011987A (es) | 2012-09-28 |
| CO6640204A2 (es) | 2013-03-22 |
| BR112012015129A2 (pt) | 2019-09-24 |
| PH12012501237A1 (en) | 2012-11-26 |
| ZA201203944B (en) | 2013-08-28 |
| CR20120335A (es) | 2012-10-31 |
| MX2012007217A (es) | 2012-07-10 |
| CL2012001671A1 (es) | 2012-11-23 |
| US20130116204A1 (en) | 2013-05-09 |
| CA2783616A1 (en) | 2011-06-30 |
| EP2516395A1 (en) | 2012-10-31 |
| CN102770412A (zh) | 2012-11-07 |
| JP2013515073A (ja) | 2013-05-02 |
| SG181891A1 (en) | 2012-07-30 |
| WO2011079091A1 (en) | 2011-06-30 |
| US8716252B2 (en) | 2014-05-06 |
| AU2010333767A1 (en) | 2012-07-05 |
| RU2012131164A (ru) | 2014-01-27 |
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