KR20120006063A - 셀룰라이트 치료용 아교질분해효소 - Google Patents

셀룰라이트 치료용 아교질분해효소 Download PDF

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Publication number
KR20120006063A
KR20120006063A KR1020117028099A KR20117028099A KR20120006063A KR 20120006063 A KR20120006063 A KR 20120006063A KR 1020117028099 A KR1020117028099 A KR 1020117028099A KR 20117028099 A KR20117028099 A KR 20117028099A KR 20120006063 A KR20120006063 A KR 20120006063A
Authority
KR
South Korea
Prior art keywords
gelatinase
cellulite
purified
injected
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020117028099A
Other languages
English (en)
Korean (ko)
Inventor
마리 에이. 바데일멘테
알렉산더 비. 다굼
Original Assignee
더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕 filed Critical 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕
Publication of KR20120006063A publication Critical patent/KR20120006063A/ko
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/06Preparations for care of the skin for countering cellulitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
KR1020117028099A 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소 Ceased KR20120006063A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US77569006P 2006-02-22 2006-02-22
US60/775,690 2006-02-22
US11/703,269 2007-02-07
US11/703,269 US20070224184A1 (en) 2006-02-22 2007-02-07 Method for treating cellulite

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020087022877A Division KR20080108996A (ko) 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소

Publications (1)

Publication Number Publication Date
KR20120006063A true KR20120006063A (ko) 2012-01-17

Family

ID=38325147

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020117028099A Ceased KR20120006063A (ko) 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소
KR1020087022877A Ceased KR20080108996A (ko) 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020087022877A Ceased KR20080108996A (ko) 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소

Country Status (19)

Country Link
US (4) US20070224184A1 (enExample)
EP (1) EP1991258B1 (enExample)
JP (5) JP5775658B2 (enExample)
KR (2) KR20120006063A (enExample)
AU (1) AU2007221225B2 (enExample)
BR (1) BRPI0708186A2 (enExample)
CA (1) CA2643171C (enExample)
DK (1) DK1991258T3 (enExample)
ES (1) ES2553184T3 (enExample)
HR (1) HRP20151182T1 (enExample)
HU (1) HUE025918T2 (enExample)
IL (1) IL193639A (enExample)
MX (1) MX2008010767A (enExample)
NZ (1) NZ570642A (enExample)
PL (1) PL1991258T3 (enExample)
PT (1) PT1991258E (enExample)
RS (1) RS54372B1 (enExample)
SI (1) SI1991258T1 (enExample)
WO (1) WO2007100675A2 (enExample)

Families Citing this family (25)

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US6958150B2 (en) 1994-12-15 2005-10-25 Advance Biofactures Of Curacao, N.V. Reduction of adipose tissue
KR20090130158A (ko) * 2005-01-21 2009-12-17 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕 유착 관절낭염을 치료하는 방법
US20070224184A1 (en) * 2006-02-22 2007-09-27 The Research Foundation Of The State University Of New York Method for treating cellulite
US20090233885A1 (en) * 2006-07-14 2009-09-17 Duncan Diane I Compositions and Methods for Fat Reduction
US10071143B1 (en) 2007-05-03 2018-09-11 The Research Foundation For The State University Of New York Methods for non-surgical treatment of carpal tunnel syndrome
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
WO2010102262A1 (en) 2009-03-06 2010-09-10 Halozyme, Inc. Temperature sensitive mutants of matrix metalloprotease 1 und uses thereof
JP5284239B2 (ja) * 2009-10-07 2013-09-11 株式会社メタコ スクリーン装置
FR2966734B1 (fr) * 2010-10-29 2014-07-18 Max Rombi Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides
EP3581199B1 (en) * 2011-10-21 2023-05-31 Endo Global Ventures Methods of treatment or reduction of edematous-fibrosclerotic panniculopathy
CA2861033C (en) 2012-01-12 2017-07-25 Auxilium International Holdings, Inc. Clostridium histolyticum enzymes and methods for the use thereof
WO2014066622A2 (en) 2012-10-24 2014-05-01 The Research Foundation For The State University Of New York Use of collagenase to treat glaucoma
WO2014107745A1 (en) 2013-01-07 2014-07-10 Halozyme, Inc. Metal sensitive mutants of matrix metalloproteases and uses thereof
EP2968484B1 (en) 2013-03-15 2020-11-25 BioSpecifics Technologies Corporation Treatment method and product for uterine fibroids using purified collagenase
US10117892B2 (en) 2013-08-29 2018-11-06 Allergan, Inc. Devices and methods for reducing the appearance of cellulite
CN103751102A (zh) 2014-01-15 2014-04-30 上海交通大学 一种胶原酶温敏水凝胶及其制备方法和应用
KR20230003601A (ko) * 2017-03-01 2023-01-06 엔도 벤쳐즈 리미티드 셀룰라이트를 평가하고 치료하기 위한 장치 및 방법
CN118325876A (zh) 2017-03-28 2024-07-12 恩多风投有限公司 生产胶原酶的改进方法
WO2020021332A2 (en) * 2018-07-12 2020-01-30 Endo Global Aesthetics Limited Injection techniques for the treatment of cellulite
WO2020021330A2 (en) * 2018-07-12 2020-01-30 Endo Global Aesthetics Limited Injection techniques for the treatment of cellulite
KR20210079291A (ko) * 2018-09-18 2021-06-29 엔도 글로벌 에스테틱스 리미티드 셀룰라이트를 치료하기 위한 조성물 및 방법
US20220305094A1 (en) 2019-01-06 2022-09-29 Endo Global Aesthetics Limited Collagenase formulations and methods of producing the same
EP4045078A1 (en) 2019-10-15 2022-08-24 The Johns Hopkins University Treatment of uterine fibroids using purified collagenase
BR112022010042A2 (pt) * 2019-11-26 2022-08-16 Standard Of Care Corp Composições de hialuronidase e métodos de uso da mesma para tratar celulite
IL316852A (en) * 2022-05-10 2025-01-01 Endo Global Aesthetics Ltd Methods for reducing collagenase-mediated bruising in a subject with cellulite

Family Cites Families (19)

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US4338300A (en) * 1981-02-05 1982-07-06 The Regents Of The University Of California Use of purified clostridial collangenase in the treatment of Peyronie's disease
US4524065A (en) * 1983-08-04 1985-06-18 Bio-Specifics N.V. Method for the prevention and treatment of scars with enzymes
US4645668A (en) * 1983-08-04 1987-02-24 Biospecifics, Nv Method for the prevention and treatment of scars with enzymes
US5393792A (en) * 1991-11-20 1995-02-28 Advance Biofactures Of Curacao, N.V. High dosage topical forms of collagenase
US5332503A (en) * 1993-04-16 1994-07-26 Baxter International Inc. Process for purifying collagenase
JP3028852B2 (ja) * 1994-06-24 2000-04-04 ロシュ ダイアグノスティックス コーポレーション ヒストリチクス菌から得られるコラゲナーゼおよび2つの他のプロテアーゼの精製混合物
US5589171A (en) * 1994-08-22 1996-12-31 Advance Biofactures Of Curacao Treatment of Dupuytren's disease with collagenase
CA2158822C (en) * 1994-09-27 2008-12-23 Kusuki Nishioka Therapeutic agent for rheumatic disease
US6958150B2 (en) * 1994-12-15 2005-10-25 Advance Biofactures Of Curacao, N.V. Reduction of adipose tissue
US5830741A (en) * 1996-12-06 1998-11-03 Boehringer Mannheim Corporation Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease
US6086872A (en) * 1997-03-27 2000-07-11 Advance Biofactures Of Curacao, Nv Amelioration of dupuytren's disease
TR200001789T2 (tr) * 1997-10-03 2000-10-23 Lavipharm Laboratories, Inc. Prolamin-bitki kutuplu lipit kompozisyonu, bunun hazırlama ve uygulama metodu
US6022539A (en) * 1999-06-03 2000-02-08 Advance Biofactures Of Curacao Amelioration of peyronie's disease
US6358539B1 (en) * 1999-08-20 2002-03-19 Howard Murad Pharmaceutical compositions for reducing the appearance of cellulite
KR20090130158A (ko) * 2005-01-21 2009-12-17 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕 유착 관절낭염을 치료하는 방법
US20070224184A1 (en) * 2006-02-22 2007-09-27 The Research Foundation Of The State University Of New York Method for treating cellulite
US7811560B2 (en) * 2006-01-30 2010-10-12 Auxilium Us Holdings, Llc Compositions and methods for treating collagen-mediated diseases
JO3400B1 (ar) * 2010-09-30 2019-10-20 Ferring Bv مركب صيدلاني من كاربيتوسين
US20210169844A1 (en) * 2019-12-10 2021-06-10 Tulex Pharmaceuticals Inc. Compositions and methods for treating epilepsy, seizures and other conditions

Also Published As

Publication number Publication date
US20190053995A1 (en) 2019-02-21
NZ570642A (en) 2012-03-30
JP2018199733A (ja) 2018-12-20
EP1991258B1 (en) 2015-08-12
US20070224184A1 (en) 2007-09-27
JP2016204396A (ja) 2016-12-08
RS54372B1 (sr) 2016-04-28
JP6649449B2 (ja) 2020-02-19
JP5775658B2 (ja) 2015-09-09
HRP20151182T1 (hr) 2016-01-01
WO2007100675A2 (en) 2007-09-07
US10123959B2 (en) 2018-11-13
IL193639A0 (en) 2011-08-01
JP2020015771A (ja) 2020-01-30
EP1991258A2 (en) 2008-11-19
AU2007221225B2 (en) 2010-02-11
JP6498167B2 (ja) 2019-04-10
IL193639A (en) 2015-01-29
JP2009527570A (ja) 2009-07-30
US20160279046A1 (en) 2016-09-29
CA2643171C (en) 2018-10-02
MX2008010767A (es) 2008-09-01
JP6853331B2 (ja) 2021-03-31
WO2007100675A3 (en) 2007-11-15
KR20080108996A (ko) 2008-12-16
PL1991258T3 (pl) 2016-04-29
US20220249348A1 (en) 2022-08-11
BRPI0708186A2 (pt) 2011-05-24
AU2007221225A1 (en) 2007-09-07
ES2553184T3 (es) 2015-12-04
DK1991258T3 (en) 2015-11-16
HUE025918T2 (en) 2016-05-30
JP2015134840A (ja) 2015-07-27
PT1991258E (pt) 2015-11-24
CA2643171A1 (en) 2007-09-07
SI1991258T1 (sl) 2016-02-29

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