KR20110110097A - 수난용성 성분을 위한 메조포러스 물질 부형제 - Google Patents
수난용성 성분을 위한 메조포러스 물질 부형제 Download PDFInfo
- Publication number
- KR20110110097A KR20110110097A KR1020117012169A KR20117012169A KR20110110097A KR 20110110097 A KR20110110097 A KR 20110110097A KR 1020117012169 A KR1020117012169 A KR 1020117012169A KR 20117012169 A KR20117012169 A KR 20117012169A KR 20110110097 A KR20110110097 A KR 20110110097A
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- South Korea
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- mesoporous
- active ingredient
- composition
- pharmaceutically active
- pharmaceutical composition
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- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/02—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10901608P | 2008-10-28 | 2008-10-28 | |
| US61/109,016 | 2008-10-28 |
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| KR20110110097A true KR20110110097A (ko) | 2011-10-06 |
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| EP (1) | EP2349336B1 (https=) |
| JP (1) | JP2012506904A (https=) |
| KR (1) | KR20110110097A (https=) |
| WO (1) | WO2010050897A1 (https=) |
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| DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| US10952965B2 (en) * | 2009-05-15 | 2021-03-23 | Baxter International Inc. | Compositions and methods for drug delivery |
| AU2011303849A1 (en) * | 2010-09-14 | 2013-04-04 | Nanologica Ab | Super-saturating delivery vehicles for poorly water-soluble pharmaceutical and cosmetic active ingredients |
| PL3135656T3 (pl) | 2011-06-20 | 2019-07-31 | H. Lundbeck A/S | Deuterowane 1-piperazyno-3-fenyloindany do leczenia schizofrenii |
| GB201212866D0 (en) * | 2012-07-20 | 2012-09-05 | Formac Pharmaceuticals Nv | Dry granulates of mesoporous silica powders |
| CA3024640A1 (en) * | 2012-11-06 | 2014-05-15 | Sigrid Therapeutics Ab | A porous silica material for use as a pharmaceutical or dietary active ingredient |
| EP2934495B1 (en) * | 2012-12-21 | 2017-07-19 | National Health Research Institutes | Mesoporous silica nanoparticles for oil absorption |
| KR20160137626A (ko) * | 2014-03-31 | 2016-11-30 | 메사추세츠 인스티튜트 오브 테크놀로지 | 제약상 활성 종을 포함하는 화합물을 함유한 다공성 물질 |
| CN104027814B (zh) * | 2014-05-29 | 2016-02-24 | 福州大学 | 一种通过氨基修饰后双重载药的介孔二氧化硅 |
| RU2017106094A (ru) * | 2014-08-01 | 2018-09-04 | Джонсон энд Джонсон Консьюмер Инк. | Композиции ядер |
| JP6696082B2 (ja) * | 2014-08-01 | 2020-05-20 | イクノス サイエンシズ エスエー | Ｍｐｇｅｓ−１阻害剤を含むナノ粒子製剤 |
| GB201502073D0 (en) | 2015-02-09 | 2015-03-25 | Cubic Pharmaceuticals Ltd And Delta Pharmaceuticals Ltd | HDEG technology |
| US10252251B2 (en) | 2015-08-28 | 2019-04-09 | Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno | Production of organic materials using solid catalysts |
| EP3463375A1 (en) * | 2016-06-03 | 2019-04-10 | M Et P Pharma AG | Nasal pharmaceutical compositions with a porous excipient |
| CN106755231B (zh) * | 2016-11-29 | 2020-11-24 | 大连工业大学 | 一种血管紧张素转化酶抑制肽的提取方法 |
| CN110461340A (zh) | 2017-01-20 | 2019-11-15 | 马特恩制药股份公司 | 用于降低暴露于空气污染物的风险的鼻用药物组合物 |
| CN110678206B (zh) * | 2017-05-19 | 2023-03-21 | 株式会社德山 | 医药原料药载体及其制造方法 |
| BR112021008732A2 (pt) | 2018-11-07 | 2021-08-03 | Disruptive Materials Pharma Ab | ingredientes farmacêuticos amorfos ativos compreendendo carbonato de magnésio mesoporoso substancialmente amorfo |
| US11123309B2 (en) | 2018-11-15 | 2021-09-21 | Imam Abdulrahman Bin Faisal University | Methods for drug delivery, tumor imaging, and oxidative dehydrogenation using hierarchical ZSM-5 complex |
| EP3891134A1 (en) | 2018-12-03 | 2021-10-13 | H. Lundbeck A/S | Prodrugs of 4-((1r,3s)-6-chloro-3-phenyl-2,3-dihydro-1h-inden-1-yl)-1,2,2-trimethylpiperazine and 4-((1/r,3s)-6-chloro-3-(phenyl-d5)-2,3-dihydro-1h-inden-1-yl)-2,2-dimethy-1-(methyl-d3)piperazine |
| US11458092B2 (en) | 2018-12-14 | 2022-10-04 | NuVessl, Inc. | Composition with enhanced passenger molecule loading |
| WO2020154770A1 (en) * | 2019-01-31 | 2020-08-06 | Macquarie University | Complexes and compositions comprising probucol and uses thereof |
| JP7260353B2 (ja) * | 2019-03-25 | 2023-04-18 | 株式会社ファンケル | コエンザイムｑ１０の固体分散体 |
| GB201909137D0 (en) * | 2019-06-25 | 2019-08-07 | Univ Aston | Mesoporous polymeric particulate material |
| JP2021042173A (ja) * | 2019-09-12 | 2021-03-18 | 株式会社ファンケル | クルクミン固体分散体 |
| WO2021224313A1 (en) * | 2020-05-06 | 2021-11-11 | Disruptive Materials Pharma Ab | Novel amorphous active pharmaceutical ingredients |
| EP4333817A4 (en) * | 2021-05-06 | 2025-12-31 | Univ Hong Kong Chinese | REALIZATION OF THE NANO-AMORPHIC STATE OF MATERIALS INSIDE NANOPOROUS MATRICES |
| US12458602B2 (en) * | 2021-05-06 | 2025-11-04 | The Chinese University Of Hong Kong | Realizing the nano-amorphous state of materials inside nano-porous templates |
| CN115300448A (zh) * | 2021-05-06 | 2022-11-08 | 香港中文大学 | 在纳米多孔模板内实现材料的纳米非晶态 |
| US20240180838A1 (en) * | 2022-12-05 | 2024-06-06 | Rutgers, The State University Of New Jersey | Nanoparticle (np) compositions and methods of use thereof |
Family Cites Families (11)
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| IT1227626B (it) * | 1988-11-28 | 1991-04-23 | Vectorpharma Int | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
| DE4327063A1 (de) | 1993-08-12 | 1995-02-16 | Kirsten Dr Westesen | Ubidecarenon-Partikel mit modifizierten physikochemischen Eigenschaften |
| US5922299A (en) * | 1996-11-26 | 1999-07-13 | Battelle Memorial Institute | Mesoporous-silica films, fibers, and powders by evaporation |
| US7919119B2 (en) | 1999-05-27 | 2011-04-05 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| US7172770B2 (en) * | 2001-02-19 | 2007-02-06 | Board Of Regents, The University Of Texas System | Mesoporous compositions for use in drug delivery |
| US6630170B2 (en) * | 2001-04-26 | 2003-10-07 | Board Of Regents The University Of Texas System | Mesoporous compositions and method of preparation |
| EE200400034A (et) * | 2001-06-22 | 2004-06-15 | Pfizer Products Inc. | Amorfse ravimaine adsorbaatide farmatseutilised kompositsioonid |
| US6653319B1 (en) | 2001-08-10 | 2003-11-25 | University Of Kentucky Research Foundation | Pharmaceutical formulation for poorly water soluble camptothecin analogues |
| GB0315012D0 (en) * | 2003-06-27 | 2003-07-30 | Leuven K U Res & Dev | Zeotiles |
| US7981441B2 (en) | 2004-02-18 | 2011-07-19 | The Board Of Trustees Of The Leland Stanford Junior University | Drug delivery systems using mesoporous oxide films |
| WO2005110592A1 (en) | 2004-05-17 | 2005-11-24 | Yki, Ytkemiska Institutet Ab | Mesoporous particles loaded with active substance |
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- 2009-02-18 WO PCT/SG2009/000053 patent/WO2010050897A1/en not_active Ceased
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- 2009-02-18 JP JP2011534455A patent/JP2012506904A/ja active Pending
- 2009-02-18 KR KR1020117012169A patent/KR20110110097A/ko not_active Withdrawn
Also Published As
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| WO2010050897A1 (en) | 2010-05-06 |
| EP2349336B1 (en) | 2017-11-22 |
| US8778401B2 (en) | 2014-07-15 |
| US20110244002A1 (en) | 2011-10-06 |
| EP2349336A4 (en) | 2013-10-23 |
| EP2349336A1 (en) | 2011-08-03 |
| JP2012506904A (ja) | 2012-03-22 |
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