KR20110086705A - 생리학적 조건 하에 거대분자의 응집을 감소시키는 방법 및 제제 - Google Patents
생리학적 조건 하에 거대분자의 응집을 감소시키는 방법 및 제제 Download PDFInfo
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- KR20110086705A KR20110086705A KR1020117011124A KR20117011124A KR20110086705A KR 20110086705 A KR20110086705 A KR 20110086705A KR 1020117011124 A KR1020117011124 A KR 1020117011124A KR 20117011124 A KR20117011124 A KR 20117011124A KR 20110086705 A KR20110086705 A KR 20110086705A
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- Prior art keywords
- antibody
- ser
- val
- cyclodextrin
- thr
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Life Sciences & Earth Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11544108P | 2008-11-17 | 2008-11-17 | |
| US61/115,441 | 2008-11-17 |
Publications (1)
| Publication Number | Publication Date |
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| KR20110086705A true KR20110086705A (ko) | 2011-07-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020117011124A Ceased KR20110086705A (ko) | 2008-11-17 | 2009-11-16 | 생리학적 조건 하에 거대분자의 응집을 감소시키는 방법 및 제제 |
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| US (2) | US20110305639A1 (enExample) |
| EP (1) | EP2358395A4 (enExample) |
| JP (2) | JP2012509269A (enExample) |
| KR (1) | KR20110086705A (enExample) |
| CN (1) | CN102281903B (enExample) |
| AR (1) | AR074357A1 (enExample) |
| AU (1) | AU2009313754A1 (enExample) |
| BR (1) | BRPI0916072A2 (enExample) |
| CA (1) | CA2742988A1 (enExample) |
| CL (1) | CL2011001132A1 (enExample) |
| IL (1) | IL212533A0 (enExample) |
| MX (1) | MX2011005051A (enExample) |
| PE (1) | PE20120169A1 (enExample) |
| RU (1) | RU2563823C2 (enExample) |
| TW (1) | TW201032826A (enExample) |
| WO (1) | WO2010057107A1 (enExample) |
| ZA (1) | ZA201103006B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10854528B2 (en) | 2017-11-03 | 2020-12-01 | Samsung Electronics Co., Ltd. | Semiconductor package including organic interposer |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ME01775B (me) | 2003-11-05 | 2011-02-28 | Glycart Biotechnology Ag | Cd20 antitijela sa povećanim afinitetom vezivanja za fc receptor i efektornom funkcijom |
| TW201438738A (zh) | 2008-09-16 | 2014-10-16 | Genentech Inc | 治療進展型多發性硬化症之方法 |
| JP5341059B2 (ja) | 2010-11-09 | 2013-11-13 | 株式会社大塚製薬工場 | 幹細胞懸濁液 |
| SG11201405475UA (en) * | 2012-03-07 | 2014-10-30 | Cadila Healthcare Ltd | Pharmaceutical formulations of tnf-alpha antibodies |
| US8883979B2 (en) | 2012-08-31 | 2014-11-11 | Bayer Healthcare Llc | Anti-prolactin receptor antibody formulations |
| MX385713B (es) | 2013-03-13 | 2025-03-18 | Seagen Inc | Ciclodextrina y formulaciones de conjugados anticuerpo-fármaco. |
| US10525137B2 (en) * | 2015-12-30 | 2020-01-07 | Genentech, Inc. | Formulations with reduced degradation of polysorbate |
| GB201604124D0 (en) * | 2016-03-10 | 2016-04-27 | Ucb Biopharma Sprl | Pharmaceutical formulation |
| MX2021009851A (es) | 2019-02-18 | 2021-09-10 | Lilly Co Eli | Formulacion de anticuerpos terapeuticos. |
| US20230236199A1 (en) * | 2020-04-23 | 2023-07-27 | Eli Lilly And Company | Subcutaneous absorption and bioavailability of antibodies |
| RU2754509C1 (ru) * | 2020-12-21 | 2021-09-02 | федеральное государственное бюджетное образовательное учреждение высшего образования "Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации | Способ лечения первичной мембранозной нефропатии с нефротическим синдромом и повышенным уровнем анти-plar2 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5997856A (en) * | 1988-10-05 | 1999-12-07 | Chiron Corporation | Method and compositions for solubilization and stabilization of polypeptides, especially proteins |
| AU6818094A (en) * | 1993-04-22 | 1994-11-08 | Depotech Corporation | Cyclodextrin liposomes encapsulating pharmacologic compounds and methods for their use |
| JP2000226336A (ja) * | 1998-11-30 | 2000-08-15 | Sankyo Co Ltd | 免疫グロブリン製剤 |
| CN100389821C (zh) * | 1999-10-04 | 2008-05-28 | 希龙公司 | 稳定化的含多肽的液体药物组合物 |
| MXPA03011793A (es) * | 2001-06-29 | 2004-04-02 | Maxygen Holdings Ltd | Formulaciones de interferon. |
| DE10228049A1 (de) * | 2002-06-24 | 2004-01-15 | Merck Patent Gmbh | Flüssige Zubereitung enthaltend Oligopeptide |
| US7960512B2 (en) * | 2003-01-09 | 2011-06-14 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
| JP4817068B2 (ja) * | 2003-01-14 | 2011-11-16 | イエダ・リサーチ・アンド・ディベロップメント・カンパニー・リミテッド | 全身性エリテマトーデスの治療のためのペプチドの非経口製剤 |
| US20050158303A1 (en) * | 2003-04-04 | 2005-07-21 | Genentech, Inc. | Methods of treating IgE-mediated disorders comprising the administration of high concentration anti-IgE antibody formulations |
| DK1610820T4 (da) * | 2003-04-04 | 2013-11-04 | Genentech Inc | Høj-koncentration antistof- og proteinformuleringer |
| HRP20090325T1 (en) * | 2003-04-09 | 2009-07-31 | Genentech | Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor |
| DE10361599A1 (de) * | 2003-12-24 | 2005-07-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Flüssigformulierung von Antikörperkonjugaten |
| US7318918B2 (en) * | 2004-05-19 | 2008-01-15 | Maxygen, Inc. | Interferon-alpha polypeptides and conjugates |
| US20060128654A1 (en) * | 2004-12-10 | 2006-06-15 | Chunlin Tang | Pharmaceutical formulation of cytidine analogs and derivatives |
| DOP2006000029A (es) * | 2005-02-07 | 2006-08-15 | Genentech Inc | Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas) |
| WO2007019232A2 (en) * | 2005-08-03 | 2007-02-15 | Immunogen, Inc. | Immunoconjugate formulations |
| CN101553504A (zh) * | 2006-12-11 | 2009-10-07 | 豪夫迈·罗氏有限公司 | Aβ抗体胃肠外制剂 |
| CN101204374A (zh) * | 2006-12-18 | 2008-06-25 | 宜兴市天石饲料有限公司 | 一种包被复合型多价高效蛋黄抗体 |
| CA2701032C (en) * | 2007-09-27 | 2021-01-26 | Amgen Inc. | Pharmaceutical formulations |
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2009
- 2009-11-16 KR KR1020117011124A patent/KR20110086705A/ko not_active Ceased
- 2009-11-16 PE PE2011001040A patent/PE20120169A1/es not_active Application Discontinuation
- 2009-11-16 JP JP2011536560A patent/JP2012509269A/ja active Pending
- 2009-11-16 MX MX2011005051A patent/MX2011005051A/es not_active Application Discontinuation
- 2009-11-16 CA CA2742988A patent/CA2742988A1/en not_active Abandoned
- 2009-11-16 CN CN2009801546640A patent/CN102281903B/zh not_active Expired - Fee Related
- 2009-11-16 WO PCT/US2009/064610 patent/WO2010057107A1/en not_active Ceased
- 2009-11-16 TW TW098138926A patent/TW201032826A/zh unknown
- 2009-11-16 EP EP09826919.4A patent/EP2358395A4/en not_active Withdrawn
- 2009-11-16 BR BRPI0916072A patent/BRPI0916072A2/pt not_active IP Right Cessation
- 2009-11-16 AR ARP090104434A patent/AR074357A1/es unknown
- 2009-11-16 RU RU2011124550/15A patent/RU2563823C2/ru not_active IP Right Cessation
- 2009-11-16 AU AU2009313754A patent/AU2009313754A1/en not_active Abandoned
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2011
- 2011-04-20 ZA ZA2011/03006A patent/ZA201103006B/en unknown
- 2011-04-28 IL IL212533A patent/IL212533A0/en unknown
- 2011-05-13 US US13/107,137 patent/US20110305639A1/en not_active Abandoned
- 2011-05-16 CL CL2011001132A patent/CL2011001132A1/es unknown
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2013
- 2013-06-10 US US13/914,094 patent/US20140093493A1/en not_active Abandoned
-
2015
- 2015-07-30 JP JP2015150264A patent/JP2016020350A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10854528B2 (en) | 2017-11-03 | 2020-12-01 | Samsung Electronics Co., Ltd. | Semiconductor package including organic interposer |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010057107A1 (en) | 2010-05-20 |
| CN102281903B (zh) | 2013-11-13 |
| ZA201103006B (en) | 2012-07-25 |
| JP2016020350A (ja) | 2016-02-04 |
| BRPI0916072A2 (pt) | 2015-11-10 |
| RU2011124550A (ru) | 2012-12-27 |
| RU2563823C2 (ru) | 2015-09-20 |
| US20140093493A1 (en) | 2014-04-03 |
| JP2012509269A (ja) | 2012-04-19 |
| IL212533A0 (en) | 2011-06-30 |
| CN102281903A (zh) | 2011-12-14 |
| CL2011001132A1 (es) | 2012-07-20 |
| AR074357A1 (es) | 2011-01-12 |
| AU2009313754A1 (en) | 2010-05-20 |
| CA2742988A1 (en) | 2010-05-20 |
| TW201032826A (en) | 2010-09-16 |
| EP2358395A4 (en) | 2013-11-20 |
| US20110305639A1 (en) | 2011-12-15 |
| PE20120169A1 (es) | 2012-02-29 |
| EP2358395A1 (en) | 2011-08-24 |
| MX2011005051A (es) | 2011-06-01 |
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