KR20110074870A - 간염을 치료하기 위한 peg-인터페론, 리바비린 및 vx-950을 포함하는 치료 요법 - Google Patents

간염을 치료하기 위한 peg-인터페론, 리바비린 및 vx-950을 포함하는 치료 요법 Download PDF

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KR20110074870A
KR20110074870A KR1020117008799A KR20117008799A KR20110074870A KR 20110074870 A KR20110074870 A KR 20110074870A KR 1020117008799 A KR1020117008799 A KR 1020117008799A KR 20117008799 A KR20117008799 A KR 20117008799A KR 20110074870 A KR20110074870 A KR 20110074870A
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South Korea
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weeks
peginterferon
administered
ribavirin
patients
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Korean (ko)
Inventor
로버트 에스 카우프만
시릴 장 카미유 티튜
라몬 폴로
히스바이크 루돌프 피터 게르하르트 반
마리아 글로리아 부몬트
가스통 라파엘 피치오
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버텍스 파마슈티칼스 인코포레이티드
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Publication of KR20110074870A publication Critical patent/KR20110074870A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020117008799A 2008-09-24 2009-09-24 간염을 치료하기 위한 peg-인터페론, 리바비린 및 vx-950을 포함하는 치료 요법 Withdrawn KR20110074870A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US9984908P 2008-09-24 2008-09-24
US61/099,849 2008-09-24
US10965508P 2008-10-30 2008-10-30
US61/109,655 2008-10-30
US24304109P 2009-09-16 2009-09-16
US61/243,041 2009-09-16

Publications (1)

Publication Number Publication Date
KR20110074870A true KR20110074870A (ko) 2011-07-04

Family

ID=41396114

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117008799A Withdrawn KR20110074870A (ko) 2008-09-24 2009-09-24 간염을 치료하기 위한 peg-인터페론, 리바비린 및 vx-950을 포함하는 치료 요법

Country Status (11)

Country Link
US (2) US20110236351A1 (https=)
EP (1) EP2328656A1 (https=)
JP (1) JP2012503669A (https=)
KR (1) KR20110074870A (https=)
CN (1) CN102316935A (https=)
AU (1) AU2009296653A1 (https=)
CA (1) CA2738477A1 (https=)
EA (1) EA201170484A1 (https=)
IL (1) IL211810A0 (https=)
MX (1) MX2011003121A (https=)
WO (1) WO2010036799A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8399615B2 (en) 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates
EP2358736A1 (en) * 2008-10-15 2011-08-24 Intermune, Inc. Therapeutic antiviral peptides
WO2010093843A2 (en) * 2009-02-12 2010-08-19 Vertex Pharmaceuticals Incorporated Hcv combination therapies
TW201116540A (en) * 2009-10-01 2011-05-16 Intermune Inc Therapeutic antiviral peptides
DE202012012955U1 (de) 2011-10-21 2014-07-14 Abbvie Inc. Eine Kombination aus mindestens zwei direkt wirkenden antiviralen Wirkstoffen (DAAs) für die Verwendung zur Behandlung von HCV
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
EP2583677A3 (en) 2011-10-21 2013-07-03 Abbvie Inc. Methods for treating HCV comprising at least two direct acting antiviral agent, ribavirin but not interferon.
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR049297A1 (es) * 2004-06-08 2006-07-12 Vertex Pharma Una composicion farmaceutica y dispersiones solidas de vx-950 (inhibidor de la proteasa de hcv ns3/4a) y proceso de obtencion
TW201424733A (zh) * 2004-10-29 2014-07-01 Vertex Pharma 劑量型式
CN101479389A (zh) * 2006-04-26 2009-07-08 沃泰克斯药物股份有限公司 丙肝病毒感染生物标记
JP2010528013A (ja) * 2007-05-21 2010-08-19 バーテックス ファーマシューティカルズ インコーポレイテッド Vx−950を含む用量形態およびそれらの投与レジメン

Also Published As

Publication number Publication date
EP2328656A1 (en) 2011-06-08
AU2009296653A1 (en) 2010-04-01
CA2738477A1 (en) 2010-04-01
US20110236351A1 (en) 2011-09-29
IL211810A0 (en) 2011-06-30
US8871812B2 (en) 2014-10-28
US20130101554A1 (en) 2013-04-25
EA201170484A1 (ru) 2012-03-30
JP2012503669A (ja) 2012-02-09
CN102316935A (zh) 2012-01-11
WO2010036799A1 (en) 2010-04-01
MX2011003121A (es) 2011-04-21

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PA0105 International application

Patent event date: 20110418

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 20111006

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid