KR20110053354A - 폐동맥 고혈압의 치료 - Google Patents
폐동맥 고혈압의 치료 Download PDFInfo
- Publication number
- KR20110053354A KR20110053354A KR1020117005744A KR20117005744A KR20110053354A KR 20110053354 A KR20110053354 A KR 20110053354A KR 1020117005744 A KR1020117005744 A KR 1020117005744A KR 20117005744 A KR20117005744 A KR 20117005744A KR 20110053354 A KR20110053354 A KR 20110053354A
- Authority
- KR
- South Korea
- Prior art keywords
- lower alkyl
- phenyl
- substituted
- amino
- pulmonary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| CA2671029A1 (en) | 2009-06-30 | 2010-12-30 | James S. Baldassarre | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
| EP3007689B1 (en) | 2013-01-10 | 2018-03-07 | Pulmokine, Inc. | Non-selective kinase inhibitors |
| JP6799201B2 (ja) * | 2013-07-31 | 2020-12-16 | アヴァリン ファーマ インク． | エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用 |
| US9925184B2 (en) | 2013-10-11 | 2018-03-27 | Pulmokine, Inc. | Spray-dry formulations |
| RU2763525C2 (ru) | 2016-10-27 | 2021-12-30 | Пульмокин, Инк. | Комбинированная терапия для лечения легочной гипертензии |
| KR102486434B1 (ko) | 2016-11-08 | 2023-01-09 | 리아타 파마슈티컬즈 홀딩스, 엘엘씨 | 바독솔론 메틸 또는 이의 유사체를 사용하는 알포트 증후군의 치료 방법 |
| WO2019157337A1 (en) * | 2018-02-08 | 2019-08-15 | Pulmokine, Inc. | Formulations of kinase inhibitors and prostanoids |
| EP3968963A4 (en) | 2019-05-16 | 2023-02-01 | Aerovate Therapeutics, Inc. | IMATINIB FORMULATIONS, THEIR PREPARATION AND USES |
| US11464776B2 (en) | 2019-05-16 | 2022-10-11 | Aerovate Therapeutics, Inc. | Inhalable imatinib formulations, manufacture, and uses thereof |
| WO2021108303A1 (en) * | 2019-11-25 | 2021-06-03 | PHPrecisionMed, LLC | Pharmaceutical compositions for the treatment of pulmonary hypertension |
| TWI893032B (zh) | 2019-12-13 | 2025-08-11 | 日商日本新藥股份有限公司 | 作為pdgf受體激酶抑制劑之化合物及組合物 |
| JP2023542298A (ja) * | 2020-09-11 | 2023-10-06 | プルモシム セラピューティクス リミテッド ライアビリティ カンパニー | 肺高血圧症を治療又は予防する組成物及び方法 |
| CA3199324A1 (en) | 2020-11-17 | 2022-05-27 | Adam Marc Silverstein | Inhaled imatinib for pulmonary hypertension field |
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| US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| GB0215676D0 (en) * | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
| US20060154936A1 (en) * | 2002-10-25 | 2006-07-13 | Lasky Joseph A | Use of n-'5-'4-(4-methylpiperaziomethyl)-benzoylamido!-2-methylphenyl!-4-(3-pyridyl)2-pyridine-amine for the treatment of pulmonary hypertension |
| GB0325031D0 (en) * | 2003-10-27 | 2003-12-03 | Novartis Ag | Organic compounds |
| ES2373912T3 (es) * | 2005-01-28 | 2012-02-10 | Novartis Ag | Uso de pirimidilaminobenzamidas para el tratamiento de enfermedades que responden a la modulación de la actividad de quinasa tie-2. |
| MX2007013738A (es) * | 2005-05-02 | 2008-01-24 | Novartis Ag | Derivados de pirimidilaminobenzamida para sindrome hipereosinofilico. |
| ES2549327T3 (es) * | 2005-12-06 | 2015-10-27 | Novartis Ag | Derivados de pirimidilaminobenzamida para el tratamiento de la neurofibromatosis |
| WO2008058037A1 (en) * | 2006-11-03 | 2008-05-15 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
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| US20110190313A1 (en) | 2011-08-04 |
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| NZ590839A (en) | 2013-02-22 |
| CN102123711A (zh) | 2011-07-13 |
| MX2011001668A (es) | 2011-03-25 |
| CA2732789A1 (en) | 2010-02-18 |
| MA32617B1 (fr) | 2011-09-01 |
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| JP2011530607A (ja) | 2011-12-22 |
| WO2010019540A1 (en) | 2010-02-18 |
| AU2009282104A1 (en) | 2010-02-18 |
| IL210922A0 (en) | 2011-04-28 |
| RU2011109078A (ru) | 2012-09-20 |
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