KR20110052573A - 심한 출혈을 멈추게 하고 누출을 봉합하기 위한 의료용 접착제 - Google Patents

심한 출혈을 멈추게 하고 누출을 봉합하기 위한 의료용 접착제 Download PDF

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Publication number
KR20110052573A
KR20110052573A KR1020117001034A KR20117001034A KR20110052573A KR 20110052573 A KR20110052573 A KR 20110052573A KR 1020117001034 A KR1020117001034 A KR 1020117001034A KR 20117001034 A KR20117001034 A KR 20117001034A KR 20110052573 A KR20110052573 A KR 20110052573A
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KR
South Korea
Prior art keywords
component
functional
tissue
isocyanate
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020117001034A
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English (en)
Korean (ko)
Inventor
하이케 헤크로트
부르크하르트 쾨흘러
세바스티안 되르
Original Assignee
바이엘 머티리얼사이언스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 바이엘 머티리얼사이언스 아게 filed Critical 바이엘 머티리얼사이언스 아게
Publication of KR20110052573A publication Critical patent/KR20110052573A/ko
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0094Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing macromolecular fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/04Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06At least partially resorbable materials
    • A61L17/10At least partially resorbable materials containing macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/089Reaction retarding agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/10Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/48Polyethers
    • C08G18/4833Polyethers containing oxyethylene units
    • C08G18/4837Polyethers containing oxyethylene units and other oxyalkylene units
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04Polyurethanes
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09JADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J175/00Adhesives based on polyureas or polyurethanes; Adhesives based on derivatives of such polymers
    • C09J175/04Polyurethanes
    • C09J175/12Polyurethanes from compounds containing nitrogen and active hydrogen, the nitrogen atom not being part of an isocyanate group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Composite Materials (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
KR1020117001034A 2008-07-17 2009-07-04 심한 출혈을 멈추게 하고 누출을 봉합하기 위한 의료용 접착제 Withdrawn KR20110052573A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08012901A EP2145634A1 (de) 2008-07-17 2008-07-17 Medizinische Klebstoffe zur Stillung schwerwiegender Blutungen und Abdichtung von Leckagen
EP08012901.8 2008-07-17

Publications (1)

Publication Number Publication Date
KR20110052573A true KR20110052573A (ko) 2011-05-18

Family

ID=39877989

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117001034A Withdrawn KR20110052573A (ko) 2008-07-17 2009-07-04 심한 출혈을 멈추게 하고 누출을 봉합하기 위한 의료용 접착제

Country Status (13)

Country Link
US (4) US9764058B2 (https=)
EP (2) EP2145634A1 (https=)
JP (1) JP2011527915A (https=)
KR (1) KR20110052573A (https=)
CN (1) CN102089015A (https=)
AU (1) AU2009270521A1 (https=)
BR (1) BRPI0916192A2 (https=)
CA (1) CA2730850A1 (https=)
DK (1) DK2307063T3 (https=)
ES (1) ES2533077T3 (https=)
RU (1) RU2011105724A (https=)
TW (1) TW201016248A (https=)
WO (1) WO2010006714A2 (https=)

Cited By (1)

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KR20240145909A (ko) 2023-03-28 2024-10-07 포항공과대학교 산학협력단 대사물의 고분자 나노입자 및 이의 용도

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EP2145634A1 (de) * 2008-07-17 2010-01-20 Bayer MaterialScience AG Medizinische Klebstoffe zur Stillung schwerwiegender Blutungen und Abdichtung von Leckagen
DE102010019504A1 (de) 2010-05-06 2011-11-10 Bayer Materialscience Ag Polyisocyanatprepolymere und deren Verwendung
WO2012013673A1 (de) 2010-07-29 2012-02-02 Bayer Materialscience Ag Bioabbaubarer gewebekleber
PL2673311T3 (pl) 2011-02-09 2015-02-27 Bayer Materialscience Ag Kleje tkankowe na bazie trójfunkcjonalnych asparginianów
WO2012107375A1 (de) 2011-02-09 2012-08-16 Bayer Materialscience Ag Gewebekleber auf basis stickstoffmodifizierter aspartate
WO2012107376A1 (de) 2011-02-09 2012-08-16 Bayer Materialscience Ag Gewebekleber auf basis aminosubstituierter triacetale
EP2699615B1 (de) 2011-04-19 2015-06-17 Medical Adhesive Revolution GmbH Medizinischer klebstoff zur stillung von blutungen
WO2012143358A1 (de) * 2011-04-19 2012-10-26 Bayer Materialscience Ag Gewebekleber mit beschleunigter aushärtung
EP2543395A1 (de) * 2011-07-04 2013-01-09 Bayer MaterialScience AG Schichtaufbau zum Verschließen von Gewebeleckagen
ES2694826T3 (es) * 2011-12-20 2018-12-27 Adhesys Medical Gmbh Prepolímero con funcionalidad isocianato para un adhesivo de tejidos biodegradable
ES2576702T3 (es) * 2012-01-09 2016-07-08 Adhesys Medical Gmbh Agentes de curado (a base de aspartato) modificados por ésteres de beta-aminoácido y su uso en adhesivos de tejido de poliurea
EP2695900B1 (en) * 2012-08-06 2019-03-20 Novachem Industriale S.r.l. Process for preparing a two-component polyurethane adhesive system
KR20170134572A (ko) 2015-04-06 2017-12-06 쓰리엠 이노베이티브 프로퍼티즈 컴파니 제거가능한 필름 형성 겔 조성물 및 이의 적용 방법
JP7155544B2 (ja) * 2018-03-02 2022-10-19 東洋紡株式会社 ポリカルボン酸誘導体
WO2019241484A1 (en) 2018-06-14 2019-12-19 Ecolab Usa Inc. Carboxy alkyl-ester anti-agglomerants for the control of natural gas hydrates
EP3698723A1 (de) 2019-02-20 2020-08-26 Adhesys Medical GmbH Applikator für einen zwei-komponenten gewebekleber
WO2022013345A1 (de) 2020-07-17 2022-01-20 Adhesys Medical Gmbh Kit aus einem zwei-komponenten gewebekleber und einer textilen struktur zur stärkung des bindegewebes nach einer operation sowie dessen verwendung
CN116782959A (zh) * 2020-12-23 2023-09-19 彼得斯外科公司 包括nco封端的氨基甲酸酯预聚物的止血组织粘合剂组合物
DE102021102484A1 (de) 2021-02-03 2022-08-04 Adhesys Medical Gmbh Kit für die Gefäßanastomose aus einem zwei-Komponenten Gewebekleber und einer Gefäßprothese sowie dessen Verwendung
DE102021106358A1 (de) 2021-03-16 2022-09-22 Adhesys Medical Gmbh Gewebekleber in Form eines Zweikomponenten-Klebstoffs zur Verwendung bei der Pankreasanastomose im Rahmen der Pankreasresektion
EP4104870A1 (de) 2021-06-15 2022-12-21 Adhesys Medical GmbH Gewebekleber in form eines zweikomponenten-klebstoffs zur verwendung als bakterielle barriere bei der wundbehandlung, insbesondere nach chirurgischen eingriffen
CN114053474A (zh) * 2021-11-24 2022-02-18 华南理工大学 一种具备止血功能的医用胶粘剂及其使用方法

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EP2145634A1 (de) * 2008-07-17 2010-01-20 Bayer MaterialScience AG Medizinische Klebstoffe zur Stillung schwerwiegender Blutungen und Abdichtung von Leckagen
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240145909A (ko) 2023-03-28 2024-10-07 포항공과대학교 산학협력단 대사물의 고분자 나노입자 및 이의 용도

Also Published As

Publication number Publication date
EP2307063B1 (de) 2014-12-31
BRPI0916192A2 (pt) 2018-05-29
US10391198B2 (en) 2019-08-27
CA2730850A1 (en) 2010-01-21
US10117963B2 (en) 2018-11-06
AU2009270521A1 (en) 2010-01-21
EP2307063A2 (de) 2011-04-13
US20190030206A1 (en) 2019-01-31
US20110123479A1 (en) 2011-05-26
US20200046875A1 (en) 2020-02-13
US20170326268A1 (en) 2017-11-16
TW201016248A (en) 2010-05-01
US9764058B2 (en) 2017-09-19
RU2011105724A (ru) 2012-08-27
WO2010006714A3 (de) 2010-09-30
EP2145634A1 (de) 2010-01-20
US10722609B2 (en) 2020-07-28
WO2010006714A2 (de) 2010-01-21
CN102089015A (zh) 2011-06-08
JP2011527915A (ja) 2011-11-10
DK2307063T3 (en) 2015-04-07
ES2533077T3 (es) 2015-04-07

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Date Code Title Description
PA0105 International application

Patent event date: 20110114

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid