RU2011105724A - Медицинские клеящие вещества для остановки тяжелых кровотечений и герметизация от утечки жидкости - Google Patents
Медицинские клеящие вещества для остановки тяжелых кровотечений и герметизация от утечки жидкости Download PDFInfo
- Publication number
- RU2011105724A RU2011105724A RU2011105724/15A RU2011105724A RU2011105724A RU 2011105724 A RU2011105724 A RU 2011105724A RU 2011105724/15 A RU2011105724/15 A RU 2011105724/15A RU 2011105724 A RU2011105724 A RU 2011105724A RU 2011105724 A RU2011105724 A RU 2011105724A
- Authority
- RU
- Russia
- Prior art keywords
- component
- isocyanate
- aspartic acid
- polyols
- functional
- Prior art date
Links
- 239000000853 adhesive Substances 0.000 title 1
- 230000000740 bleeding effect Effects 0.000 title 1
- 239000007788 liquid Substances 0.000 title 1
- 238000007789 sealing Methods 0.000 title 1
- 239000012530 fluid Substances 0.000 claims abstract 10
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims abstract 9
- 235000003704 aspartic acid Nutrition 0.000 claims abstract 9
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims abstract 9
- 150000002148 esters Chemical class 0.000 claims abstract 9
- 239000012766 organic filler Substances 0.000 claims abstract 9
- 229920005862 polyol Polymers 0.000 claims abstract 8
- 150000003077 polyols Chemical class 0.000 claims abstract 8
- 206010052428 Wound Diseases 0.000 claims abstract 5
- 208000027418 Wounds and injury Diseases 0.000 claims abstract 5
- -1 aliphatic isocyanates Chemical class 0.000 claims abstract 5
- 239000008280 blood Substances 0.000 claims abstract 5
- 210000004369 blood Anatomy 0.000 claims abstract 5
- 239000012948 isocyanate Substances 0.000 claims abstract 5
- 239000000203 mixture Substances 0.000 claims abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 4
- 150000001412 amines Chemical class 0.000 claims abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 4
- 239000001257 hydrogen Substances 0.000 claims abstract 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims abstract 4
- 230000003993 interaction Effects 0.000 claims abstract 3
- 230000001413 cellular effect Effects 0.000 claims abstract 2
- 238000000034 method Methods 0.000 claims abstract 2
- 229920000728 polyester Polymers 0.000 claims 2
- 239000000047 product Substances 0.000 claims 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- 239000004721 Polyphenylene oxide Substances 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 239000012084 conversion product Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims 1
- 229920001281 polyalkylene Polymers 0.000 claims 1
- 229920000570 polyether Polymers 0.000 claims 1
- 239000003106 tissue adhesive Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 abstract 2
- 210000000056 organ Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
- A61L24/0094—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/10—At least partially resorbable materials containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/089—Reaction retarding agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/48—Polyethers
- C08G18/4833—Polyethers containing oxyethylene units
- C08G18/4837—Polyethers containing oxyethylene units and other oxyalkylene units
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
- C08L75/04—Polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J175/00—Adhesives based on polyureas or polyurethanes; Adhesives based on derivatives of such polymers
- C09J175/04—Polyurethanes
- C09J175/12—Polyurethanes from compounds containing nitrogen and active hydrogen, the nitrogen atom not being part of an isocyanate group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Composite Materials (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Polyurethanes Or Polyureas (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Adhesives Or Adhesive Processes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08012901A EP2145634A1 (de) | 2008-07-17 | 2008-07-17 | Medizinische Klebstoffe zur Stillung schwerwiegender Blutungen und Abdichtung von Leckagen |
| EP08012901.8 | 2008-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2011105724A true RU2011105724A (ru) | 2012-08-27 |
Family
ID=39877989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011105724/15A RU2011105724A (ru) | 2008-07-17 | 2009-07-04 | Медицинские клеящие вещества для остановки тяжелых кровотечений и герметизация от утечки жидкости |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9764058B2 (https=) |
| EP (2) | EP2145634A1 (https=) |
| JP (1) | JP2011527915A (https=) |
| KR (1) | KR20110052573A (https=) |
| CN (1) | CN102089015A (https=) |
| AU (1) | AU2009270521A1 (https=) |
| BR (1) | BRPI0916192A2 (https=) |
| CA (1) | CA2730850A1 (https=) |
| DK (1) | DK2307063T3 (https=) |
| ES (1) | ES2533077T3 (https=) |
| RU (1) | RU2011105724A (https=) |
| TW (1) | TW201016248A (https=) |
| WO (1) | WO2010006714A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2145634A1 (de) * | 2008-07-17 | 2010-01-20 | Bayer MaterialScience AG | Medizinische Klebstoffe zur Stillung schwerwiegender Blutungen und Abdichtung von Leckagen |
| DE102010019504A1 (de) | 2010-05-06 | 2011-11-10 | Bayer Materialscience Ag | Polyisocyanatprepolymere und deren Verwendung |
| WO2012013673A1 (de) | 2010-07-29 | 2012-02-02 | Bayer Materialscience Ag | Bioabbaubarer gewebekleber |
| PL2673311T3 (pl) | 2011-02-09 | 2015-02-27 | Bayer Materialscience Ag | Kleje tkankowe na bazie trójfunkcjonalnych asparginianów |
| WO2012107375A1 (de) | 2011-02-09 | 2012-08-16 | Bayer Materialscience Ag | Gewebekleber auf basis stickstoffmodifizierter aspartate |
| WO2012107376A1 (de) | 2011-02-09 | 2012-08-16 | Bayer Materialscience Ag | Gewebekleber auf basis aminosubstituierter triacetale |
| EP2699615B1 (de) | 2011-04-19 | 2015-06-17 | Medical Adhesive Revolution GmbH | Medizinischer klebstoff zur stillung von blutungen |
| WO2012143358A1 (de) * | 2011-04-19 | 2012-10-26 | Bayer Materialscience Ag | Gewebekleber mit beschleunigter aushärtung |
| EP2543395A1 (de) * | 2011-07-04 | 2013-01-09 | Bayer MaterialScience AG | Schichtaufbau zum Verschließen von Gewebeleckagen |
| ES2694826T3 (es) * | 2011-12-20 | 2018-12-27 | Adhesys Medical Gmbh | Prepolímero con funcionalidad isocianato para un adhesivo de tejidos biodegradable |
| ES2576702T3 (es) * | 2012-01-09 | 2016-07-08 | Adhesys Medical Gmbh | Agentes de curado (a base de aspartato) modificados por ésteres de beta-aminoácido y su uso en adhesivos de tejido de poliurea |
| EP2695900B1 (en) * | 2012-08-06 | 2019-03-20 | Novachem Industriale S.r.l. | Process for preparing a two-component polyurethane adhesive system |
| KR20170134572A (ko) | 2015-04-06 | 2017-12-06 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 제거가능한 필름 형성 겔 조성물 및 이의 적용 방법 |
| JP7155544B2 (ja) * | 2018-03-02 | 2022-10-19 | 東洋紡株式会社 | ポリカルボン酸誘導体 |
| WO2019241484A1 (en) | 2018-06-14 | 2019-12-19 | Ecolab Usa Inc. | Carboxy alkyl-ester anti-agglomerants for the control of natural gas hydrates |
| EP3698723A1 (de) | 2019-02-20 | 2020-08-26 | Adhesys Medical GmbH | Applikator für einen zwei-komponenten gewebekleber |
| WO2022013345A1 (de) | 2020-07-17 | 2022-01-20 | Adhesys Medical Gmbh | Kit aus einem zwei-komponenten gewebekleber und einer textilen struktur zur stärkung des bindegewebes nach einer operation sowie dessen verwendung |
| CN116782959A (zh) * | 2020-12-23 | 2023-09-19 | 彼得斯外科公司 | 包括nco封端的氨基甲酸酯预聚物的止血组织粘合剂组合物 |
| DE102021102484A1 (de) | 2021-02-03 | 2022-08-04 | Adhesys Medical Gmbh | Kit für die Gefäßanastomose aus einem zwei-Komponenten Gewebekleber und einer Gefäßprothese sowie dessen Verwendung |
| DE102021106358A1 (de) | 2021-03-16 | 2022-09-22 | Adhesys Medical Gmbh | Gewebekleber in Form eines Zweikomponenten-Klebstoffs zur Verwendung bei der Pankreasanastomose im Rahmen der Pankreasresektion |
| EP4104870A1 (de) | 2021-06-15 | 2022-12-21 | Adhesys Medical GmbH | Gewebekleber in form eines zweikomponenten-klebstoffs zur verwendung als bakterielle barriere bei der wundbehandlung, insbesondere nach chirurgischen eingriffen |
| CN114053474A (zh) * | 2021-11-24 | 2022-02-18 | 华南理工大学 | 一种具备止血功能的医用胶粘剂及其使用方法 |
| EP4591856A1 (en) | 2023-03-28 | 2025-07-30 | POSTECH Research and Business Development Foundation | Polymer nanoparticles of metabolites and use thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4740534A (en) * | 1985-08-30 | 1988-04-26 | Sanyo Chemical Industries, Ltd. | Surgical adhesive |
| ES2062188T3 (es) * | 1989-06-23 | 1994-12-16 | Bayer Ag | Procedimiento para la elaboracion de revestimientos. |
| US5243012A (en) | 1992-06-10 | 1993-09-07 | Miles Inc. | Polyurea coating compositions having improved pot lives |
| WO1998054224A1 (en) * | 1997-05-28 | 1998-12-03 | Tapic International Co., Ltd. | Collagen gel |
| US6355829B2 (en) * | 1999-09-02 | 2002-03-12 | Bayer Corporation | Aspartate-terminated urea/urethane prepolymers and their use in coating compositions |
| DE10246708A1 (de) * | 2002-10-07 | 2004-04-15 | Bayer Ag | Zweikomponenten-Systeme für die Herstellung elastischer Beschichtungen |
| US20050129733A1 (en) * | 2003-12-09 | 2005-06-16 | Milbocker Michael T. | Surgical adhesive and uses therefore |
| US8044234B2 (en) * | 2005-05-05 | 2011-10-25 | Tyco Healthcare Group Lp | Bioabsorbable surgical composition |
| ES2669059T3 (es) * | 2005-07-28 | 2018-05-23 | Bioptigen, Inc. | Sistema de formación de imagen de tomografía de coherencia óptica en el dominio de la frecuencia |
| WO2007127198A2 (en) * | 2006-04-24 | 2007-11-08 | Incept, Llc | Protein crosslinkers, crosslinking methods and applications thereof |
| EP2011808A1 (de) * | 2007-07-03 | 2009-01-07 | Bayer MaterialScience AG | Medizinische Klebstoffe für die Chirurgie |
| EP2095832A1 (de) * | 2008-02-28 | 2009-09-02 | Bayer MaterialScience AG | Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile. |
| EP2145634A1 (de) * | 2008-07-17 | 2010-01-20 | Bayer MaterialScience AG | Medizinische Klebstoffe zur Stillung schwerwiegender Blutungen und Abdichtung von Leckagen |
| EP2275466A1 (de) * | 2009-07-16 | 2011-01-19 | Bayer MaterialScience AG | Polyharnstoff-basierter Gewebekleber |
| WO2012107375A1 (de) * | 2011-02-09 | 2012-08-16 | Bayer Materialscience Ag | Gewebekleber auf basis stickstoffmodifizierter aspartate |
-
2008
- 2008-07-17 EP EP08012901A patent/EP2145634A1/de not_active Ceased
-
2009
- 2009-07-04 CN CN2009801273319A patent/CN102089015A/zh active Pending
- 2009-07-04 RU RU2011105724/15A patent/RU2011105724A/ru not_active Application Discontinuation
- 2009-07-04 US US13/054,673 patent/US9764058B2/en not_active Expired - Fee Related
- 2009-07-04 DK DK09776953.3T patent/DK2307063T3/en active
- 2009-07-04 EP EP09776953.3A patent/EP2307063B1/de not_active Not-in-force
- 2009-07-04 CA CA2730850A patent/CA2730850A1/en not_active Abandoned
- 2009-07-04 JP JP2011517778A patent/JP2011527915A/ja not_active Withdrawn
- 2009-07-04 WO PCT/EP2009/004833 patent/WO2010006714A2/de not_active Ceased
- 2009-07-04 BR BRPI0916192-9A patent/BRPI0916192A2/pt not_active IP Right Cessation
- 2009-07-04 KR KR1020117001034A patent/KR20110052573A/ko not_active Withdrawn
- 2009-07-04 AU AU2009270521A patent/AU2009270521A1/en not_active Abandoned
- 2009-07-04 ES ES09776953.3T patent/ES2533077T3/es active Active
- 2009-07-16 TW TW098124025A patent/TW201016248A/zh unknown
-
2017
- 2017-08-03 US US15/667,744 patent/US10117963B2/en not_active Expired - Fee Related
-
2018
- 2018-10-01 US US16/148,272 patent/US10391198B2/en not_active Expired - Fee Related
-
2019
- 2019-06-25 US US16/451,283 patent/US10722609B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2307063B1 (de) | 2014-12-31 |
| KR20110052573A (ko) | 2011-05-18 |
| BRPI0916192A2 (pt) | 2018-05-29 |
| US10391198B2 (en) | 2019-08-27 |
| CA2730850A1 (en) | 2010-01-21 |
| US10117963B2 (en) | 2018-11-06 |
| AU2009270521A1 (en) | 2010-01-21 |
| EP2307063A2 (de) | 2011-04-13 |
| US20190030206A1 (en) | 2019-01-31 |
| US20110123479A1 (en) | 2011-05-26 |
| US20200046875A1 (en) | 2020-02-13 |
| US20170326268A1 (en) | 2017-11-16 |
| TW201016248A (en) | 2010-05-01 |
| US9764058B2 (en) | 2017-09-19 |
| WO2010006714A3 (de) | 2010-09-30 |
| EP2145634A1 (de) | 2010-01-20 |
| US10722609B2 (en) | 2020-07-28 |
| WO2010006714A2 (de) | 2010-01-21 |
| CN102089015A (zh) | 2011-06-08 |
| JP2011527915A (ja) | 2011-11-10 |
| DK2307063T3 (en) | 2015-04-07 |
| ES2533077T3 (es) | 2015-04-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2011105724A (ru) | Медицинские клеящие вещества для остановки тяжелых кровотечений и герметизация от утечки жидкости | |
| AU2008202473B2 (en) | Foam control for synthetic adhesive/sealant | |
| US8324292B2 (en) | Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant | |
| CA2738494C (en) | Multi-armed catechol compound blends | |
| Chen et al. | Elastomeric nanocomposites as cell delivery vehicles and cardiac support devices | |
| Guo et al. | The multifaceted nature of catechol chemistry: Bioinspired pH-initiated hyaluronic acid hydrogels with tunable cohesive and adhesive properties | |
| RU2010140659A (ru) | Медицинские клеи с биоактивными соединениями для хирургии | |
| US20070276121A1 (en) | Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | |
| EP1973957A1 (en) | Diisocyanate terminated macromer and method of making | |
| ES2370513T3 (es) | Macrómetro terminado en diisocianato y formulación del mismo para uso como adhesivo o agente de selladura interno. | |
| US20230001046A1 (en) | Biocompatible adhesives and methods of manufacture thereof | |
| WO2017044896A1 (en) | Biomedical adhesive and sealant compositions and methods of use | |
| Liu et al. | A tunable multifunctional hydrogel with balanced adhesion, toughness and self-healing ability prepared by photopolymerization under green LED irradiation for wound dressing | |
| Zeng et al. | Versatile underwater pressure sensitive adhesive: UV curing synthesis and substrate-independent adhesion | |
| Ates et al. | Biomimetic approach to tunable adhesion of polyurethane adhesives through Fe3+ crosslinking and hydrophobic tween units with balance of adhesion/cohesion forces | |
| Nuswantoro et al. | Bio-based adhesives for orthopedic applications: Sources, preparation, characterization, challenges, and future perspectives | |
| Boursier et al. | Biocompatible Glues: Recent Progress and Emerging Frontiers in Surgical Adhesion | |
| KR20250093395A (ko) | 자극-반응성 의료용 접착제 조성물, 물품, 및 방법 | |
| CN101343527B (zh) | 可溶胀的聚合物用于密封的用途 | |
| US20060281874A1 (en) | Method of making a diisocyanate terminated macromer | |
| US8071663B2 (en) | Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant | |
| RU2018111319A (ru) | Клей для восстановления мениска | |
| WO2005092404A1 (ja) | 医療用接着剤 | |
| US20070167617A1 (en) | Method of making a diisocyanate terminated macromer | |
| RU2583936C1 (ru) | Медицинский клей |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA94 | Acknowledgement of application withdrawn (non-payment of fees) |
Effective date: 20131202 |