KR20110026237A - Skin wash comprising extract of sunflower seed - Google Patents

Abstract

PURPOSE: A skin cleansing composition containing Helianthus annuus seed extract is provided to prevent moisture loss and to suppress skin irritation and allergy. CONSTITUTION: A skin cleansing composition contains Helianthus annuus seed extract as an active ingredient. The Helianthus annuus extract is obtained by solvent extraction, supercritical extraction, or sonication extraction. The used solvents in solvent extraction are water, anhydrous or hydrous low alcohol of 104 carbon atoms, ethylene glycol, glycerol, propylene glycol, acetone, tetrahydrofuran, acetonitrile, pyridine, and acetic acid.

Description

Skin cleanser composition containing sunflower seed extract {SKIN WASH COMPRISING EXTRACT OF SUNFLOWER SEED}

The present invention relates to a skin cleanser composition containing the sunflower seed extract as an active ingredient, which can contain a large amount of water in the stratum corneum, and excellent moisture retention effect of the skin by blocking moisture loss to the outside, and moisturizes the skin. And it is excellent in the softening effect and relates to a skin cleanser composition that can be used safely without side effects on the skin, such as irritation to the skin, allergens.

The skin is divided into three layers of epidermis, dermis, and subcutaneous fat tissue in order from the outside, and serves to protect the human body from physical and chemical stimuli of the external environment. Controls the evaporation of moisture out of the body The stratum corneum of the epidermis contains 10 to 20% of moisture and exists at the outermost part of the human body to suppress evaporation of moisture from the body, while preventing excess moisture from penetrating from the outside. Maintaining the proper level of water loss is known as the sebaceous component and epidermal lipid, which are the lipid membrane components of the keratinocyte layer.

The stratum corneum layer contains a hydrophilic, water-retaining substance called Natural Moisturizing Factor (NMF), which helps the skin to maintain flexibility and maintain proper moisture. However, when the moisture content of the stratum corneum is less than 10%, the skin becomes rough and the body loses its protective function, causing aging. For example, in the case of dry skin, the aggregation of keratinocytes is weakened, and scaling phenomenon in which keratinocytes are peeled off from the surface of the skin like a scale fragment appears. The dry skin is because the moisture content of the keratinocyte layer is less than that of normal skin. In addition, due to changes in the environment or changes in life patterns, various stresses and environmental pollution from social life, frequent facial washing caused by makeup habits, and natural skin aging due to age increase, moisture in the stratum corneum decreases and the skin dries. Problems related to moisturizing the skin are becoming more and more important as phenomena such as surface roughness, skin loss, and dullness appear.

For this reason, it is very important to properly maintain the moisture content of the stratum corneum, and conventionally, as a moisturizer, a humectant or NMF component having a property of absorbing moisture is added, or a natural water-soluble component containing these components is added. Was used. These humectants include polyols, such as glycerin, sorbitol, dipropylene glycol, and 1,3-butylene glycol. They exhibit excellent moisturizing properties when applied to the skin, but are very sticky or unpleasant due to their inherent viscosity and physical properties. I can feel it. On the other hand, NMF components such as sodium pyrrolidone carboxylic acid, sodium lactate, urea, or natural water-soluble components containing these components have a strong electrolytic problem that impairs the stability of the composition.

Another way to maintain the water content of the stratum corneum is to increase the water retention in the stratum corneum by using a closed moisturizer that prevents moisture evaporation. Closed moisturizers include lipids such as oils, waxes, ceramides, and the like. These closed moisturizers tend to form oily membranes on the skin and suppress evaporation of moisture, so that the moisturizing effect is sustained.

Recently, many products for skin using natural products have been developed to reduce skin irritation caused by various chemicals. Natural ingredients have less side effects on the skin, and the development value is increasing as consumers' response to products using natural ingredients has recently increased.

In the present invention, in consideration of the above problems of the skin products, the skin moisturizing effect and supple effect is excellent, and an object of the present invention is to provide a skin cleanser that can be safely used without side effects such as skin irritation or allergy.

The skin cleanser composition of the present invention for achieving the above object is characterized in that it contains a sunflower seed extract as an active ingredient.

Here, the sunflower seed extract is preferably contained in 0.0001 to 30.0% by weight based on the whole composition, more preferably 0.1 to 15.0% by weight.

In addition, sunflower seed extract is water, anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms, liquid polyhydric alcohols such as ethylene glycol, glycerin, propylene glycol, hydrophilic solvents such as acetone, tetrahydrofuran, acetonitrile, pyridine and acetic acid and hexane Solvent extraction using an extraction solvent selected from the group consisting of hydrophobic solvents such as cyclohexane, benzene, and toluene; Supercritical extraction method; Or by ultrasonic extraction.

The present invention provides a skin cleanser containing the sunflower seed extract having a skin moisturizing effect and a softening effect as an active ingredient. Skin cleanser that contains sunflower seed extract as an active ingredient can contain a large amount of moisture in the stratum corneum and has excellent moisture retention effect and excellent skin moisturizing effect and softening effect by blocking moisture loss to the outside. In addition, there are no side effects on the skin, such as irritation and allergy, can be used safely.

Hereinafter, the present invention will be described in more detail.

Sunflower seed extract used in the skin cleanser of the present invention is obtained from sunflower (Helianthus annuus) seeds. Sunflower seeds contain about 50% oil, which contains linolenic acid, phospholipids, beta-sitosterol, glycolipids, and ceramides. Sugars contained in phosphorus range from monosaccharides to trisaccharides, and contain organic acids such as citric acid and tartaric acid and beta carotene. The protein constituting sunflower seeds is characterized by high essential amino acids, especially arginine. Phospholipids, beta sitosterol, glycolipids, and ceramides are components of the lipid membrane of the stratum corneum layer that maintains water loss at an appropriate level.

Such a sunflower seed extract is prepared by a conventional method of producing a plant extract, for example, may be prepared by extracting a pulverized product obtained by drying or grinding the sunflower seeds using a hydrophilic organic solvent or a hydrophobic organic solvent.

The hydrophilic organic solvent is a monohydric alcohol such as methyl alcohol, ethyl alcohol, 1-propanol and 1-butanol, and a dihydric alcohol such as 2-propanol and 2-butanol: trihydric alcohol such as 2-methyl-2-propanol. : Liquid polyhydric alcohols such as ethylene glycol, glycerin, propylene glycol and 1,3-butylene glycol: one or more selected from the group consisting of acetone, tetrahydrofuran, acetonitrile, pyridine and acetic acid can be used.

As the hydrophobic organic solvent, one or more selected from the group consisting of hexane, cyclohexane, carbon tetrachloride, chloroform, dichloromethane, 1,2-dichloroethane, diethyl ether, ethyl acetate, benzene, and toluene can be used.

The above extraction solvent may be used in an amount of 1 to 15% by volume based on the dry weight of the sunflower seed crushed product. After the addition of the solvent to the pulverized product using a warming method of extraction by heating for 1 to 24 hours at a temperature of 5 to 95 ℃, preferably 10 to 90 ℃, or 1 to 20 days at a low temperature of 4 to 25 ℃ A cold soak method is used.

In addition, the sunflower seed extract in the composition of the present invention includes not only the extract by the above-described extraction solvent, but also the extract that has undergone a conventional purification process. For example, decompression by carbon dioxide, extraction by supercritical extraction by high temperature, extraction by ultrasonic extraction, separation using ultrafiltration membranes with constant molecular weight cut-off values, separation by various chromatography, etc. Further active fractions obtained through various purification methods carried out are also included in the extracts in the compositions of the present invention.

In addition, the composition of the present invention provides a skin cleansing composition, characterized in that the extract is obtained by cold washing at room temperature, heat filtration, or further obtained by concentrating the solvent under reduced pressure or lyophilization.

In the skin cleanser composition according to the present invention, the sunflower seed extract is included in an amount of 0.0001 to 30.0% by weight, preferably 0.1 to 15.0% by weight based on the total composition. If the content of the extract is less than 0.0001% by weight, the moisturizing effect of the use of the sunflower seed extract is not obtained, and when the content of the extract is more than 30.0% by weight, the degree of effect increase due to the increase of the content is insignificant. There is a problem with stability and it is not economical.

The skin cleanser composition of the present invention may be prepared in any formulation commonly used in the art, and may be prepared, for example, in a liquid, solid and paste form, but is not limited thereto. Specifically, the skin cleanser composition of the present invention may be prepared with soap, liquid cleanser, face wash, bath detergent, shampoo, rinse, hair treatment, hair mousse, aftershave lotion, shaving cream, toothpaste, mouse washer and the like. In this case, fragrances, pigments, fungicides, antioxidants, preservatives, moisturizers, thickeners, inorganic salts, synthetic polymer materials and the like can be further used to improve the physical properties of the composition.

Skin cleansing agent containing the sunflower seed extract according to the present invention as an active ingredient can contain a large amount of water in the stratum corneum and excellent moisture retention effect of the skin by blocking moisture loss to the outside, skin moisturizing effect and supple effect Not only is excellent, there are no side effects on the skin, such as irritation and allergy, can be used safely.

Hereinafter, the present invention will be described in more detail with reference to Examples. The following examples are intended to illustrate the present invention more specifically, but the scope of the present invention is not limited by these examples.

Production Example : Sunflower Seed Extract

1 L of ethanol was added to 100 g of sunflower seed ground products, and the mixture was heated and extracted for 3 hours in a reflux extractor with a cooling condenser. The resultant was then filtered through a 100 mesh filter cloth, and the residue was extracted once more in the same manner. Each extract was combined and filtered with Whatman No. 2 filter paper at room temperature to remove insoluble matters, and then concentrated under reduced pressure in a distillation apparatus equipped with a cooling condenser to finally obtain 300 g of sunflower seed extract.

Example  1 to 3 and Comparative example  1 and 2

To prepare a skin cleanser composition of Examples and Comparative Examples according to a conventional method using the components shown in Table 1. In Table 1 the units are weight percent.

division Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 Sodium Laureth Sulfate 10.0 10.0 10.0 10.0 10.0 Cocamidopropyl Betaine 6.0 6.0 6.0 6.0 6.0 glycerin 3.0 3.0 3.0 3.0 3.0 Citric acid 0.6 0.6 0.6 0.6 0.6 Metal Ion Blocker 0.05 0.05 0.05 0.05 0.05 Thickener 0.5 0.5 0.5 0.5 0.5 antiseptic 0.05 0.05 0.05 0.05 0.05 Spices 0.5 0.5 0.5 0.5 0.5 Sunflower Seed Extract 0.1 5 15.0 - 35.0 Distilled water Up to 100% by weight

With respect to the skin cleanser composition prepared in Examples and Comparative Examples, the following experiment was conducted to confirm the skin moisturizing effect, skin supplement effect and skin irritation.

Effect Test Example 1 : Water retention capacity evaluation experiment

In order to evaluate the moisturizing power of the skin cleanser compositions of Examples 1 to 3 and Comparative Examples 1 and 2, a method of measuring moisture retention after washing the skin using a quantitative measure was used.

At this time, the device used a skin moisture content measuring device Skicon 200 (high frequency: 3.5 MHz) to measure the electrical conductivity of the skin. The Skicon 200 is a device for measuring the moisture content of the skin (corresponding to the keratinocyte layer) of shallow thickness at a frequency of 3.5 MHz.

In the test method, the compositions of Examples 1 to 3 and Comparative Examples 1 and 2 were used in a constant temperature and humidity chamber of 22 ° C and a relative humidity of 45% for 30 minutes by using a predetermined amount (2 mg / cm 2) in the inside of the arm of 20 test subjects, respectively. After washing three times at intervals, the water retention before and after washing was measured to compare and evaluate the increase and decrease. The results are as shown in Table 2 below.

division Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 Change rate (%) -39.8 -28.7 -16.0 -43.5 -15.6

As shown in Table 2, it can be seen that the composition of Examples 1 to 3 containing the sunflower seed extract according to the present invention has a much smaller decrease in water retention due to repeated washing, compared to the composition of Comparative Example 1. On the other hand, the composition of Comparative Example 2 containing an excessive amount of sunflower seed extract can be seen that the degree of effect increase according to the increase in content compared to Example 3 is insignificant.

Effect Test Example 2 Skin Softening Effect Experiment

In order to evaluate the softening effects on the skin of the skin cleanser compositions of Examples 1 to 3 and Comparative Examples 1 and 2, 30 soft panels were divided into samples and used to confirm the softening effect on the skin.

The score was assessed on a 5-point scale, with the following criteria:

1 point | piece: Very soft skin.

2 points | pieces: The skin is inflexible.

3 points: Normal.

4 points | pieces: The softness of skin is good.

5 points | pieces: The softness | flexibility of skin is very good.

The results obtained at this time are as shown in Table 3 below.

division Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 score 3.5 4.2 4.7 3.3 4.7

As shown in Table 3, it can be seen that the composition of Examples 1 to 3 containing sunflower seed extract according to the present invention has a higher skin softening effect than the composition of Comparative Example 1.

Effect Test Example 3 skin irritation evaluation experiment

In order to evaluate skin irritation of the skin cleanser compositions of Examples 1 to 3 and Comparative Examples 1 and 2, a closed patch test was conducted on 50 healthy adults and men.

Each sample was added to the pin chamber (approximately 0.2 g) and attached to the subject's skin for 24 hours to prevent loss of the sample using a filter paper of appropriate size. The condition was judged by two experts. By this method, the degree of stimulation and the stimulation response were evaluated according to the criteria in Table 4 below, calculated by the following equation, and the results are shown in Table 5.

Stimulus
(score) Irritation
(Reaction) Criteria 0 - No symptoms One + - Have only slight erythema reactions 2 + Clear erythema, edema but no blisters 3 ++ Clear erythema, edema, blisters 4 +++ If you have a cannon

Skin irritation index = irritation rate × (number of subjects responding) / (number of subjects)

division Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 Skin irritation 0.13 0.10 0.09 0.14 0.08

As shown in Table 5, it can be seen that the composition of Examples 1 to 3 according to the present invention exhibits a stable skin irritation index without significant difference when compared with the composition of Comparative Example.

As shown in the above results, it can be seen that the skin cleanser composition containing the sunflower seed extract of the present invention has excellent skin moisturizing effect and softening effect and low skin irritation.

Claims (4)

A skin cleanser composition containing an sunflower seed extract as an active ingredient. The skin cleanser composition of claim 1, wherein the sunflower seed extract is contained in an amount of 0.0001 to 30.0% by weight based on the total composition. The skin cleanser composition of claim 1, wherein the sunflower seed extract is contained in an amount of 0.1 to 15.0% by weight based on the total composition. The method according to any one of claims 1 to 3, wherein the sunflower seed extract is water, a liquid polyhydric alcohol containing anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms, ethylene glycol, glycerin, propylene glycol, acetone, tetrahydrofuran Solvent extraction using an hydrophilic solvent comprising acetonitrile, pyridine and acetic acid and an extraction solvent selected from the group consisting of hydrophobic solvents including hexane, cyclohexane, benzene and toluene; Supercritical extraction method; Or a skin cleanser composition obtained by an ultrasonic extraction method.