KR20110014952A - The method of preparing sexual-vigormedicine using composition of medical plants - Google Patents

Abstract

PURPOSE: A method for manufacturing aphrodisiac using herbal compositions is provided to strengthen body energy and to maintain continuous improved sexual function. CONSTITUTION: A method for manufacturing aphrodisiac comprises: a step of removing foreign materials and washing and drying; a step of mixing 20 weight parts of Corni Fructus, 18 weight parts of Eucommia ulmoides, 12 weight parts of Lycii Fructus, 10 weight parts of Dioscorea nipponica Makino, 10 weight parts of ginseng, and 6 weight parts of Acanthopanacis Cortex in 3-4 times weight of water; a step of boiling the herbs at room temperature for 12-24 hours; a step of cooling at room temperature and centrifuging to obtain an extract; a step of filtering and centrifuging; a step of concentrating by 10-15 wt% of surfactant; a step of freeze-drying in a thickness of 2-3 mm and drying in a freeze-drier; and a step of pulverizing and drying.

Description

Method of manufacturing a tablet using herbal herbal composition {THE METHOD OF PREPARING SEXUAL-VIGORMEDICINE USING COMPOSITION OF MEDICAL PLANTS}

The present invention, unlike the synthetic sexual enhancer having a temporary sexual function and side effects that have been recently released in large quantities in recent years, a method of preparing a herbal tablet made of a herbal herbal medicine that can maintain continuous sexual function by helping to bleeding and vigorously invigorating the source Specifically, based on the consent of the folk remedies and orthodox medicines, Dongbogum, Cornus, Dungchung, Gojija by identifying the components and functions of various herbal medicines that make the blood donating and vigorous and strengthen the sex. Centrifuged extracts obtained by heat-treating herbal extracts of ginseng medicinal herbs (ginseng), ginseng, ogapi and ginseng tree (ground) with water or alcoholic aqueous solution to obtain a filtrate, and the supernatant of this filtrate was concentrated under reduced pressure and lyophilized to be powdered. It relates to a method for producing a tablet using a herbal herbal composition.

Since ancient times, the desire to maintain strong energetics while maintaining youthfulness is inevitable for men's instincts. Moreover, in recent years, women's social participation rate has increased and women's status has become more prominent. Older men are taking medicine and trying to improve their physical fitness by exercise. In some cases, Viagra, Cialis, Liviro, etc., are using various synthetic stiffeners. Therefore, in order to maintain a continuous sexual function effect should be worn. As a result, the physical balance is lost and side effects occur and the use is extremely limited.

In addition, the product being released as a natural reinforcing agent is called "Sea Horse Sanxin Ring" in China, and extracts about 40 kinds of natural medicines such as Haikou Sin, Sea Horse Noxin, Deer Antler, Yin Yanggak, Pagekcheon, and Mountain medicinal extracts. Under the trade name "Oubu Undefeated", tablets of several kinds of natural pharmaceutical compositions have been released.

In addition, the domestic registration patent (Registration No. 0522176) contains 48 plant herbal medicine extracts and honey compositions including bellflower, ginseng, hawthorn, gupan, donkey, baekchul, tangerine, earthworm, casualty, sewage, etc. "Introduced in the domestic patent publication (Registration No. 10-0688252) as an animal drug as a deer antler and vegetable herbal medicine white ginseng, earthenware, Astragalus, dermis, donkey, breeding, Hodoin, white paper, ginger, bokyeong, dansam, mountain medicine Men's sexual enhancement composition consisting of more than 20 herbal ingredients and honey composition, including licorice, pageokcheon are being introduced. In addition, the domestic registration patent (registration No. 0463313) introduces "functional food for improving male sexual function" as a health functional food, and penis as an oral erectile dysfunction in which muse, loquat and euprima are developed as synthetic stabilizers. Diena is developed and released to induce erection through selective inhibition of phosphoesterase, a small enzyme in the.

Erectile dysfunction of the synthetic materials in the existing products as the sexual enhancer as described above, although most of them are temporary jeongjeonggyeong showing a certain effect on sexual function, but one or two side effects appear over a period of time and the natural animal or plant developed to date Herbal medicines are widely available and used, but it is hard to find products that have proven to be effective.

The present invention systematically analyzes the ingredients contained in the herbal herbal medicines based on Dongbobom, which is an aggregate of oriental medicine, by escaping the temporary tablets having temporary erectile function by conventional synthetic materials, and grasping the pharmacological functions and actions of the ingredients. By selecting the herbal medicine that helps blood donation and energizes the source naturally, it activates normal physiological function of nervous system, vascular system and endocrine system, and selects non-toxic herbal ingredient that produces strong positive effect. The present invention provides a method for preparing a tablet using a herbal herbal composition which gradually improves and continuously maintains it.

Remove foreign substances from vegetable herbal medicines consisting of large yellow spot, cornus oil, tofu, wolfberry, panaxima, ginseng, ogapi and ginseng tree, and dry them, and then dry them by weight to 3 ~ 4 Extract pear water by immersion at room temperature for 12-24 hours and extract it, boil it for 60-80 minutes in high pressure part maintained at 1100 Torr, cool to room temperature, centrifuge the extract and filter the supernatant of the extract filtered by filtration device. Concentrated under reduced pressure at the temperature of ℃ and then lyophilized powder is sterilized by far-infrared radiation treatment and sealed packaging or, optionally, 3 ~ 6wt% of alginic acid solution or honey to the weight of the powder to round and spherical shape It was possible to solve the method of preparing the tablet using the herbal herbal medicine formed.

The medicinal tablets made from the herbal herbal composition according to the present invention are harmless to the human body, including side effects, and are naturally sourced from the herbal composition by the ingredients and functions of the herbal composition to maintain the sexual function improvement effect and have healing effects of various adult diseases. It may be referred to as a medicinal tablet made of a vegetable herbal composition.

In the embodiment of the present invention, after removing the foreign substance from the herbal medicines and washing and drying, 20 parts by weight of large yellow spot, 20 parts by weight of cornus oil, 18 parts by weight of head worms, 12 parts by weight of goji berry, 10 parts by weight of fantail, ginseng 10 parts by weight, 3 ~ 4 times of water is added to the total weight of the herbal medicine consisting of 6 parts by weight of ogapi and 4 parts by weight of ginseng tree (Ginseng tree), followed by extraction for 12 to 24 hours at room temperature, and then boiled for 60 to 80 minutes in a high pressure part maintained at 1100 Torr. After cooling to room temperature, open the high-pressure part, centrifuge to obtain the crude drug extract extract, and then filter the filtered extract to stand still, separate the supernatant to maintain a range of 40 ~ 50 ℃ concentrated under reduced pressure to 10wt% Concentrate to ~ 15wt%, and then spread or disperse this concentrate on a flat plate made of metal or plastic with a thickness of 2 ~ 3mm. Highly laminated and dried by freeze-drying method to obtain a spongy plate-like body, pulverized it to obtain a powder, and put the powder into a far-infrared radiation chamber maintained at a temperature of 80 ~ 100 ℃, dried and sterilized with drying to less than 2wt% moisture Powders can be obtained and vacuum packed or, optionally, 3-6 wt% of a binder of honey or alginic acid with respect to powder stabilizers, to obtain cyclic or spherical tabletted tablets.

The use of a high pressure part in the above increases the temperature of the extract water to as high as 100 ℃ or more, so that the herbal components are dissolved at a high temperature of more than 100 ℃ can increase the extraction efficiency.

In addition, the quenching of the concentrated extract liquid on the plate is frozen at -40 to -70 ℃ instantaneously and freeze-drying is carried out by a conventional vacuum vacuum method.

In another embodiment of the present invention, instead of the water used as the extract of the herbal composition used in the basic example, 10-15 wt% alcohol aqueous solution as an extract and extracted at room temperature for 12 to 24 hours and then 60 to 80 at a high pressure maintained at 1100 Torr. Boil for minutes, cool to room temperature, open the high-pressure part, and centrifuge the liquid solution to obtain an extract. The filtered supernatant obtained by standing still is filtered and concentrated under reduced pressure in the temperature range of 40-50 ° C. The concentrated solution concentrated in% was sprayed and dispersed in a plate plate (stainless steel plate, synthetic resin plate) to 2 ~ 3mm thickness into a freeze dryer, and the concentrate was quenched and dried by lyophilization method to obtain a cavernous plate-like body. The powders were collected and pulverized from to obtain a powder, which was then placed in a far-infrared radiation chamber maintained at 80 to 100 ° C to within 2wt% of water. Powdered tablets sterilized with drying can be obtained and vacuum-packed or, in some cases, cyclic or spherical tablet tablets can be obtained as in the basic embodiment.

The method of the other embodiment is the same method except that 10-15wt% alcohol aqueous solution is used as the extract instead of the water used as the extract of the plant herbal composition used in the method of the basic example.

The alcohol used here is all evaporated during the room temperature extraction treatment, fermentation extraction treatment, reduced pressure concentration, freeze-drying process of the herbal herbal composition. In addition, the powder sterilized and dried in the far-infrared radiation chamber is less than 2wt% of water.

Another embodiment of the present invention is mixed with a medicinal powder obtained by extracting the plant herbal composition with water in the basic embodiment of the present invention and the medicinal powder obtained by extracting the vegetable herbal composition with an aqueous alcohol solution in another embodiment of the present invention in a 1: 1 ratio In addition, the effect of the hardener extracted with water or the alcoholic solution extracted with water according to the present invention is homogeneous.

Such a reinforcing powder may be a variety of pharmacological components as having both the component dissolved in water and the component dissolved in alcohol in the herbal plant composition.

In the present invention, when increased in the high pressure portion maintained at 1100 Torr, the temperature can be raised to 120 ° C. to increase the elution temperature, thereby increasing the elution efficiency of pharmacologically active ingredients. Alginate aqueous solution used is an extract obtained by boiling seaweed. It is viscous, cohesive and harmless, and contains high quality protein, polysaccharides, mineral trace ingredients, vitamins and medicinal ingredients. Since 0.1 ~ 0.11ppm is contained, the function of cancer suppression, heart disease prevention, anti-aging, immune strengthening, oxide reducing agent has been important recently.

In addition, the pharmacological components of the herbal medicines are eluted by water, but they are not eluted by water, but there are pharmacological components that are eluted by alcohol (ethanol), so that the extraction (elution) efficiency of the pharmacological components can be improved and alcohol has a boiling point (78.3 ℃). This lowers them completely during heat treatment or vacuum concentration.

In addition, looking at the components and functions of the medicinal tablets of the herbal composition,

The large yellow spot is also called fenugreek and planted herb in Korea and contains 6 ~ 10% of aromatic oil, 0.13% of algonoid trigonelin (C ₇ H ₇ O ₂ N), 0.05% of choline, and steroid sapogenin There are genine, diosgenin and 28% mannogalactan, which is mucus when wet. There are also 22% protein and vitamins.

In the treatment of copper, it is used as a medicine to treat tonic medicine, pore medicine, kidney and bladder diseases. Recently, research is being conducted to obtain steroid sapongenin and use it as a hormone synthesis material.

Cornus tree inhabits all mountainous areas of Korea. It is 4m high and is a small tall tree. The leaves are long oval and 6-7 pairs of branch lines are clear. Early spring yellow small flowers. Fruits are oval and ripe red.

Fruits include crystalline organic acids, glutarium, malic acid, and uric acid. The fruit peel contains the iridoid glycosides such as moronisid and loganan, and there is 13% of saponin called cornine.

Its function is to nourish the kidneys with nourishment tonic and astringent in motion therapy. It is used when sweating frequently and urinating little by little, when the back hurts, when the distance is irregular, and the acorn lacquer decoction is used as a tonic for nervous breakdown and dizziness. In addition, the medicinal tablets, which consisted of dried hawthorn roots, maple roots, stalk stems, peony roots, cinnamon tree branches, non-automatic roots, and honey, are used for the treatment of elderly back pain, diabetes mellitus, chronic kidney kidney disease, arteriosclerosis. The effect is great.

In addition, tortoiseum is also called wild birch, tortoise, obsidian tree, cotton, cotton bark, and slope bark. The composition is 2 ~ 3% of chlorogenic acid (C ₁₆ H ₁₈ O ₉ ), caffeic acid, aquabin: C ₁₅ H ₂₂ O ₉ (soluble in water, insoluble in alcohol ester acetone, benzene), rubbery, and glycosides include loganine: C ₁₇ H ₂₆ O ₁₀ (water soluble in alcohol).

In addition, there are herpagide acetate C ₂₆ H ₃₂ O ₁₂ , eucommiol C ₉ H ₁₆ O ₄ , ayugoside, leptoside, flavonoids, alkaloids, organic acids, resins, vitamin C and the like.

In addition, the skin contains organic acid, chlorogenic acid and vitamin C, a small amount of alkaloids, and 7% resin. There is also a 2% bitter taste.

Actions and functions of the bark and leaf decoction, alcohol extracts when feeding the rabbit has a distinct blood pressure lowering action. After injecting atropine, the medication will not change blood pressure. The central nervous system is excited in a small amount and suppressed in a large amount. It is believed that this drug lowers blood pressure by inhibiting the training of blood, the central and vagus nerves.

The effects of blood pressure lowering on the extracts from the rabbits and dogs and the extraction solvents were compared. That is less than what is less. Decoction with water is stronger in blood pressure than we do with alcohol.

In motion therapy, it is said that the skin is touted with regular tonic, gangjeong, soothing and pain medicine.

It is also used for hypertension (1 ~ 3 stages). It is good to use it with honey grass and decaying grass roots.

In the private sector, the bark of the cedar bark is roasted on low heat and powdered to increase postpartum blood pressure 5g at a time 2 ~ 3 times a day in hot water.

Tooth bark decoction is divided into three times a day. It is used when blood pressure (1 ~ 3 stages), arteriosclerosis, nerve pain, myositis, back pain.

Peel bark 45g (70% alcohol cold), cedar leaf 133g, appropriate amount of alcohol, 1000g total amount, high blood pressure 3-6ml at a time, eat three times a day.

Since the cedar leaf has a blood pressure lowering effect, if you decide exactly how much to use, I think it can be as much as a medicinal herb.

24kg each of bark and motherwort, 14.4kg of deciduous grass roots and lamiaceae, and 4.5kg of boiled with water, soaked with horses in a stew (15kg) to make 50,000 pills (0.3g). Take 5 tablets 3 times a day as a high blood pressure medication.

Goji berry is a well-known medicinal herb, and its fruit contains 0.1% of vitamins, the cartinoid jake xanthine (C ₄₀ H ₅₆ O ₂ ), and the fruit peel contains pisalien (C ₇₂ H ₁₁₆ O ₄ ). The first biologically active substance, scoplatin, was isolated from the Goji berries.

In addition, carotenoids and sterins were also isolated, pisalien and β-cytosterin. Leafy branches contain 1.5% diosgenin.

The leaves contain betaine, doucosterin and ascorbic acid. In the ash, Si, K, Na, Ca, Mg, Fe, P, S, Zn, F and the like were confirmed. Root bark also has betaine.

As such, some of the ingredients of wolfberry are still unknown and it is necessary to identify the active ingredient in the future. It is remarkable that the leaves obtained Dowosterone, which is found in ginseng and other okapi family.

The effect is that the fruit lowers blood pressure and has some positive effects on blood sugar.

The tonic effect of goji berries is not yet known.

Betaine is a lipid-affinity substance as one of the metabolites of choline.

Betaine hydrochloride has anti-interstitial action as a methyl group feeder for choline metabolism.

Rats given goji berry extract (1.0%) reduced total cholesterol and cognitive mass and slightly triglycerides. In control rats, total lipid mass increases in the liver. In particular, triglycerides are markedly increased and phospholipids are decreased, but liver lipid suppression is suppressed in rats given 1% and 0.1% of Goji extract. In other words, Gojijax anti-interstitial, hepatic function can be seen to be protective.

Boil the water extract of the fruits, leaves, and stems, and rub them with alcohol to make black brown powder like sand grains. This substance reduces the amount of cholesterol in the blood, so it is used to prevent and treat arteriosclerosis. The leaves are decocted like tea and drink with medicine.

Both fruit and root bark are used as a medicine. Root bark is also used for pulmonary tuberculosis and diabetes.

In motion therapy, the fruit is used as a supplement to lower back pain, helplessness, dizziness, head pain, and small calories.It is said that if you eat it for a long time, you will strengthen your bones, lighten your body, blacken your gray hair, brighten your eyes, and live long without cold and heat. have.

Goji berry fruit decoction (6 ~ 5: 200)-It is divided into three times a day as a blood tonic medicine.

Gojiberry fruit links are made of 50-60% alcohol, making 1: 5 solution. As a remedy, take 2-3 ml of water at a time and eat it three times a day.

Gugija ginseng jigolpitang is made of ginseng, goji tree root bark, shiho root, danner ginseng root, raw green onion root, 4g each, 3g each of ginseng root stem, gypsum 3g each, sol pungyeongryeong 2g, ginger, jujube, 200ml of hot water for tuberculosis disease Divided three times a day with a medicine to drink when hot.

Leaf and eggplant extract (5% diosgenin)-Has a distinctly lowering lipid activity and lowers the activity of lysozyme than atherosclerosis drugs made with fan. Thus, the branches that come as by-products during spring pruning can be used as a treatment for atherosclerosis.

Cannabis medicine is also known as Fanta and contains saponins and flavonoids in the outpost. Root stem contains glycosides such as dioxin (melting point 248 ~ 250 ℃, water decomposition, diosgenin and glucose, 2 molecules of lamnose), graziline, trilin and diosgenin C ₂₇ H ₄₂ O ₃ [(recording point 204-207 degreeC, [α] _D ²⁰ -1229 ° (chloroform)], tocologinin C ₃₁ H ₄₈ O ₇ , tocoronin, yonogenin, yononin, cogagenin, tocorogogeninic acid.

In addition, there are a lot of substances such as horses and oil in the roots and stems.

The saponin content of the rhizome varies from 0.9 to 2.2% depending on the growing season, which is high in early spring and autumn and low in summer.

When the total saponin content is 1.7%, saponin, dioschin, is about 1% and diosgenin is 0.2 ~ 0.4%.

Total saponin content was 0.9% in the root stem of D.septemloba Thunb, 0.8 (0.7)% in the root stem of D.tokoro Makino, and root of D.quinqueloba Thunb. 1.2 (0.9)% in the stem and 0.4 (0.3)% in the rhizome of D.Giraldii Kunth.

Functions and functions of the root stem water and alcohol extracts lower arterial pressure in animal experiments. The mechanism of action is to inhibit M-choline-like action and the chemosensitizer of carotid sinus. Root stem extract also increases gastrointestinal motility and resistance to radiation. The rats fed this drug died of 42% (animal fed with alcohol extract) and 52% (animal fed with water extract) when killed by 400 lengens and 90% died in the control. It is thought that the therapeutic effect of the drug against radiation damage improves metabolism and excretion function by improving blood-tissue osmoticity.

Alcohol extraction is about twice as toxic as water extract, but overall is less toxic. Saponins from root stems are less toxic and, like other saponins, are irritating to the mucous membranes.

Fanzasaponin has a prophylactic and therapeutic effect against cholesteric atherosclerosis. Recently, it has been known that many saponins act on plasma lipoproteins, causing plasma cholesterol to change dispersibility and inhibit esterification. This prevents the cholesterine from depositing on the blood wall. For example, fig tree saponin inhibits the esterification of serum cholesterol in 0.01-0.02%. Soap grass saponin and calendula saponin also have high anti-lipidemic activity. Digitonin and chycramine make cholesterine and insoluble compounds. Injecting or feeding fan masaponin (polyphonin) into rabbits normally restores experimentally induced hypercholesterolemia and the resulting increased arterial pressure. In other words, the cholesterol content is reduced from 1,040 ± 271mg% to 310 ± 78mg% and blood pressure is reduced by 40 ~ 60mmHg. It also prevents lipoid deposition and cholesteric atherosclerosis in the arteries. This mechanism is thought to be due to the combination of fan masaponin with cholesterin to make insoluble compounds and to expand peripheral cortex.

Fantasaponin also acts as a pee but does not affect the functioning of the kidneys. It also enlarges peripheral blood vessels, hardens heart contractions, slows heart rhythms, and deepens breathing.

In general, substances that enhance tissue permeability improve metabolic processes in tissues. Fantasaponin increases blood vessel-tissue permeability and improves metabolic processes in tissues, especially cholesterine metabolism. In arteriosclerosis, blood line-tissue permeability is severely reduced. Fanzamasponin is therefore considered a good atherosclerosis drug.

Used for the prevention and treatment of cerebrovascular sclerosis. In addition to general arteriosclerosis, high blood pressure arteriosclerosis, it is used for sclerosis.

Polysponin-Root stems are oiled with benzol or extract gasoline and rinsed with water. Boil the extract and dry. Or, with alcohol, we make the X with an organic solvent and drain it with water. Root stem contains saponin which is released in water and saponin which is not released. The product should contain 30-40% of saponin in water. Yellowish or light ash brown powder. It loosens well in water and shakes the aqueous solution, creating bubbles that do not go out. The hemolysis index is 2,000.

Make and write a pill. In 0.3g, 0.2g of polysponin, 0.05g of magnesium carbonate, 0.05g of horses, 0.025g of stearate, 0.03g of stearic acid, 0.009g of mulberry, or 0.1g of diosponin, 0.007g of magnesium oxide, 0.013g of horses, 0.017 g of candy and 0.003 g of calcium stearate are added.

Write from 20mg (minimum) to 0.2g (maximum) at a time. Eat twice a day after meals.

Often eat 0.1g at a time. The treatment period is 10 days in 3-4 months, then 4-5 days off and eat again.

Diosgenin is separated and used as a steroid hormone synthesis material. It is used as a root stem of big horse, chrysanthemum horse, and maple horse as well as fan horse.

Diosponin-Eat 0.1 ~ 0.2g twice a day for the purpose of preventive treatment of atherosclerosis. Take 4 days off, then eat again for 10 days to eat 2-3 months.

Ginseng is also known as ginseng, ear muffs, shoots, ginseng, sajeong, blood ginseng and is a world-famous medicine.

Roots include glycosides, essential oils, oils, amino acids, alkaloids, carbohydrates, resins, and trace elements.

Glycosides in ginseng have been studied for a long time. Glycosides previously known to be isolated from ginseng such as panakuilon, panaxin, panaxol, and ginsenin are mixtures of glycosides or panaxadiol-2-glucoside, and panacicon and α-panaxin are known as panaxadiol- It is recognized as 3-glucoside.

The glycoside components known these days are as follows.

The glycosides are named differently by researchers called panaxoxide or ginsenosides. However, all were made from protopananadiol, protopananatriol, and oleanoic acid as genes, and glucose, rhamnose, and arabinose as combined sugars.

Panaxitose has so far been separated into more than 10 individual glycosides. For example, Panaxocide A (3 molecules of glucose), Propanacanadiol, which consists of Genin, Panaxoxide B (2 molecules of Glucose, and 1 molecule of Rhamnose), Panaxousse C (3 molecules of Glucose, and 1 molecule of Rhamnose) And panaxanthide D (four molecules of glucose), panaxanthide E (four molecules of glucose and one molecule of arabinose), and panaxanthide F (six molecules of glucose), each of which has a genine as a protophanaxanatriol.

Ginsenosides are named Ginsenosides R _b1 (four molecules of glucose), R _b2 (three molecules of glucose and one molecule of _{arabinopyranose} ), and R _b3 (generated from 20- (S) -protopanaxadiol) Ginsenoside containing 3 molecules _of glucose and 1 molecule of xylose), R _{c (} 3 molecules _of glucose and 1 molecule of arabinofuranose), R _d (3 molecules of glucose) and 20 (S) -protopanaxatriol R _e (1 molecule glucose, 1 rhamnose molecule), R _f (2 molecules glucose), R _g1 (2 molecules glucose), R _g2 (1 molecule glucose, 1 molecule rhamnose), 20-Glu-R _f (glucose 3 molecules), ginsenoside R _o (2 glucose and 1 molecule of glucuronic acid) known as oleanoic acid is known.

The hydrolysis of panaxoxides (ginsenosides) with acids results in the oxidation of sugars and genes. In other words, a panaxanadiol is produced in a glycoside that uses protopanaxanadiol as a genine, and a panaxanatriol occurs in a glycoside that uses a protopanaxanatriol as a genine. As such, the genomes of panoxoxides are unstable and have not obtained the original sapogenin. Thus, it was determined by considering the structure of the original sapogenin from the composition and structure of the degradation product.

Nowadays, enzymes have been used to obtain the original sapogenin, revealing its structure. Glycosides are affected by enzymes in plants, resulting in higher or lower bound sugars. Therefore, the type of panaxoxide also varies according to the seawater, season, site and soil conditions of ginseng. The ginseng roots and fine roots of young ginseng are relatively higher in glycosides containing oleanolic acid and protopanaxanalyse diol than those of long-growing ginseng and coarse roots. Also, the longer the ginseng grows and the thicker the root, the more glycosides that contain protopanaxanatriol and protopanaxanadiol as genins.

Korean ginseng contains more glycosides that contain ProtoPanaxtriol and ProtoPanacodiol than Ginseng than P. quinquefolium L., P. japonicus C.A.Meyer and P. pseudoginseng Wall. Western ginseng, bamboo shoot ginseng, and samchil contain mainly glycosides based on oleanoic acid.

The root also contains 0.025% of Dowosterone (C ₃₅ H ₆₀ O ₆ ) as a glycoside. The root contains 0.055 ~ 0.25% of essential oils. Essential oils are terpene compounds that have the smell and bitter taste of ginseng and are called panaxen. The composition of the essential oil is not yet known. Recently, β-elemen (C ₁₅ H ₂₄ ) and falcarinol [CH ₂ = CH-CHOH- (C≡C) ₂ -CH ₂ -CH = CH- (CH ₂ ) ₆ -CH ₃ (panaxinol C ₁₇ H ₂₄ O)]. Falcarinol is found in the roots of the shell and is an unstable liquid that easily resins in the air.

The roots also contain 1.5% oil and resinous substances and 0.35 ~ 0.45% ginseng acid. Ginseng acid is a mixture of fatty acids such as palmitic acid, stearic acid, and linoleic acid, which is an ester of phytosterol. Phytoserine was about 0.29% and β-sitosterol and stigmasterol were separated. In addition, glucose, fructose and disaccharides (sucrose, maltose), trisaccharide [trisaccharide A, glucose (1α)-(2β) fructose (1β)-(2β) fructose; Trisaclide B, glucose (1α)-(6) glucose (1α)-(4); Trisaclide C, glucose (1α)-(4) glucose (1α)-(2β) tructose], about 20% of horses, vitamin B ₁ , B ₂ , B ₁₂ , C, nicotinic acid, pantothenic acid, and the like. The monosaccharide content is 1 ~ 4% in white ginseng and higher in red ginseng. Total polysaccharides are about 40% when boiled and boiled in water. 80-90% of the total polysaccharides are pectin. Pectin breaks down into about 70% of galacturonic acid, galactose, arabinose and xylose.

Roots contain amino acids such as choline 0.1-0.2%, arginine about 1%, glutamic acid, chisteine, tyrosine, and α-aminobutyric acid. And there are more than seven alkaloids. Some of them have experimental antitumor activity. Fresh roots have enzymes such as amylase.

Root has 3.7% ash. 53% of the ash is lean acid and there are many other elements. The content is more than 1% is Mg, Ca, Na, 0.1-1% is Sr, Ba, Fe, 0.05 ~ 0.01% is Al, 0.01 ~ 0.001% is Mn, Pt, Si, Ti, 0.005 ~ 0.0001 Cu being% and Pb, V and Ni below 0.0001%. And Zn, Co, B, and F.

The stem, leaves, flowers, and fruits also contain panaxoxide. In particular, there are many panasocside C (ginsenoside Rb) in the outpost and fruit flesh. The leaves have 1.5% of ginsenosides R _d , R _g1 , R _e . In addition, ginsenosides R _b1 , R _b2 , R _C , F ₁ , F ₂ , F ₃ , F6 _a - _c were identified in the leaves. Ginsenoside F does not separate from the roots. Outposts include camphorol and astragalin (camphorol-3-glucoside), glycosides of trierol, panacenoside (camphorol-3-0-glucolactoside), and luteolin-7-glucoside There are, nonacoic acid, octacosanol, clioastenol.

Function and action of ginseng acts on the nervous system. Ginseng water or alcoholic nutrient solution acts on the central nervous system, especially the high-level central nervous system. As a way of looking at EEG and conditional reflections, animal experiments show that the cerebral cortex exacerbates the excitement process and at the same time strengthens the suppression process. Thus neural activity is smooth. It also increases reflex excitability. Fatigue recovery is the pulling force and hesitation time of white mice, which shows that white mice fed ginseng are stronger than untreated white mice.

Ginseng affects the endocrine system. Pituitary gland-has a certain effect on the nerves that control the cortical system. Ginseng glycosides increase the weight of the thyroid gland, thymus, thyroid and gland in white mice. The non-saponin fraction of the roots is said to have insulin free action.

In addition, ginseng has no action similar to gonadotropin, but excites the pituitary gland to stimulate the secretion of gonadotropin from it. Thus, the maturation process of rats is accelerated and the estrous period of female rats is increased. However, this effect does not appear in rats that have had their ovaries removed.

Ginseng does not have a significant effect on blood pressure in small amounts, but it is slightly higher and lowers blood pressure in large amounts. The action of lowering blood pressure is associated with blood vessel dilation. Ginseng dilates the coronary artery, brain and fundus, which is associated with exciting the sympathetic nerve.

Water, alcohol, and ether extracts of ginseng have contractile action similar to acetylcholine and antihistamine for intestinal smooth muscle. Ginseng also acts as an Idam and increases the concentration of bilirubin and heat products. Ginseng water extract hardly inhibits respiratory movement, but alcohol extract has little effect, and runners have respiratory excitement. In addition, ginseng does not have a clear effect on the peripheral blood erythrocytes, white blood cell counts and plasma, but a small amount of long-term use increases the function of the endothelial system. But if you use a large amount of the opposite will appear. Ginseng has a prophylactic and therapeutic effect on experimental gastric ulcer in rats. Ginseng glycosides and polysaccharides have the effect of preventing and treating radiation damage in animal experiments.

Ether extract of ginseng inhibits white mouse sarcoma 180 and adenocarcinoma 755.

Ginseng is very toxic. When injected subcutaneously in white mice, the LD50 is 16.5 mg / kg. If you eat 100ml of 3% ginseng alcoholic urine solution, you will feel weak anxiety and excitement. If you eat 200ml, there are poisoning symptoms such as hives, itching, dizziness, and headache.

The components that represent the pharmacological action of ginseng have not yet been identified, but there are data that can be seen as the action of the following components. In other words, ginseng acid speeds up metabolism and excites the heart. In particular, it helps the process of oil decomposition and oxidation. Glycosides have an excitatory and gonadotropic effect on the central nervous system. In other words, there is excitement for the endocrine system. It also has carbohydrate metabolism, reduces blood sugar and speeds up glycogen synthesis. Essential oils are said to work mainly on the brain and training.

Among the glycosides, the glycosides that contain protopa-nac triol have a greater pulling force and gonadotropin than white glycosides. Pectin has anti-inflammatory and therapeutic effects on gastroduodenal ulcers.

Ginseng has long been used as a tonic, gangjeong, and blood. To examine this in more depth, the effects of ginseng on sugar, lipids, and protein metabolism are being examined.

Ginseng extracts (mostly glycosides) slowly reduce blood glucose and hepatic glycogen levels in rats that cause alloxan diabetes. Liver glycogen content is reduced to 60% in 12 hours. This shows that the glucose metabolism of ginseng is similar to insulin. The action of reducing blood sugar levels also occurs in animals that have been removed from the gland. Also, feeding ginseng with cortizone does not reduce blood sugar levels. This suggests that ginseng hypoglycemic activity is not related to corticosteroids or antagonizes each other.

Ginseng also has a good effect on lipid metabolism. Feeding ginseng glycosides into rats fed cholesterol-containing diets reduces plasma cholesterol and triglycerides. This action is in promoting catabolism and excretion of cholesterol. Licorice's glycirizine and shiho saponin also have a similar effect, which is considered to be a common action of saponin compounds.

Ginseng has been experimentally found to accelerate protein biosynthesis. As a result of feeding and comparing 20 kinds of water extracts, which are used as supplements, to rats, the effect of promoting liver biosynthesis on liver ribonucleic acid was obvious in ginseng. Ginseng glycosides enhance the activity of ribonucleic acid polymerase and accelerate the synthesis of nuclear ribonucleic acid, cytoplasmic nucleic acid, and serum proteins. It also accelerates denucleic acid synthesis and lipid synthesis in bone marrow cells of rats and doubles the division of bone marrow nucleated cells. The activity of this protein biosynthesis is expressed in saponins, or glycosides of ginseng, and weak or absent in the part without saponin reaction. Among ginseng glycosides, ginsenosides R _b2 , R _c and R _g1 were also effective. The effect was weak at R _b1 and R _e .

Therefore, the effect of ginseng glycosides on protein biosynthesis is not related to the type of gene, but to the type and number of sugars in the gene. This is inconsistent with data indicating that pananaxtriol has a greater gonadotropin and fatigue recovery effect than a glycoside that contains panaxadiol. In this regard, more specific research is needed in the future.

Ginseng glycoside extracts were used in patients with anemia based on animal experimental data on the protein biosynthesis-promoting effect of ginseng, especially the myeloid nucleus cell division, and showed little effect on aplastic anemia and nephropathy. In patients with chronic arthritis, hematocrit increased and hemoglobulin improved.

Extract containing ginseng glycosides accelerated denucleic acid synthesis and protein synthesis in testicular sperm cells of rats. Thus, ginseng extract was used for 1 ~ 5 months in patients with less sperm, the number of sperm increased 2-3 times, sperm movement became active, and testosterone-like effect was obtained. However, it did not work in patients with no sperm or very few sperm counts.

Extracts containing glycosides of ginseng accelerated the biosynthesis of total lipids and fatty acids in liver and adipose tissue in rats with ascites liver cancer, but had little effect on denucleic acid, protein, lipid and biosynthesis in cancer cells. Ginseng extract was used for 3 months in patients with gastric cancer, colon cancer, colorectal cancer, mammary cancer, and thyroid cancer. The anemia was eliminated, the taste was improved, and cancer development was suppressed in about 70% of patients. And leukopenia, which is a side effect of anticancer drugs, was improved. Since ginseng has no side effects and can be used for a long time, it is recommended to use it for the purpose of preventing cancer recurrence and the growth of cancer tissue after surgery.

Ginseng saponin has a hemolytic action and hemolytic action. Among ginseng glycosides, ginsenoside R _O containing oleanoic acid as gene is hemolytic action. Among the damalan glycosides, they appear to be different depending on the structure. Glycosides mainly composed of ProtoPanaxatriol are hemolytic action (Rh, Rg), and glycosides that contain ProtoPanaxadiol have a hemolytic action (Rb). Cenoside Rd has hemolytic action and antihemolytic activity. This example can also be seen in β-sitosterol. That is, β-sitosterol has a hemolytic action, but 3-β-D-glycoside has a clear antihemolytic activity. Anti-hemolytic components have stabilization, anti-inflammatory, and sedative effects (central inhibition) of erythrocytes and are thought to have a good effect on stabilization of cell membranes and intracellular granules.

Among the ginseng glycosides, the glycosides of the protopa-naxatriol system with hemolytic activity are centrally excited, and the glycosides of the protopa-naxadiol system with antihemolytic activity are sedative.

The fact that ginseng contains antagonistic ingredients is interpreted as a data that interprets both sides in the therapeutic effect of copper pills.

Taken together, the ginseng is good for basic metabolism, such as promoting glucose metabolism and lipid synthesis, and promoting nucleic acid and protein synthesis in nonspecific tissues and cells. This action is said to be suitable for improving the taste of rice, strengthening the stomach, healing diabetes, restoring fatigue and refreshing. In addition, the weakness of various organs in the body will have a good therapeutic effect.

This is thought to be related to the use of ginseng in ischemia and yin and not in demonstration and yang. In addition, the action of increasing the number of sperm is considered to be the basic biochemical data that explain what ginseng has been written as tonic, blood and pill.

* Application in the treatment of motion to weaken the body as a tonic weakness, disease weakness, chronic diseases, etc. 2 ~ 10g, when using a large amount of 15 ~ 35g to eat. It is very weak, and it is weak, bloated, tasteless, and it has a nausea, ginseng, white shochu, pine sprinkle, licorice, and mixes the same amount to make 7g of water and drink it (Sagunjatang).

Ginseng has no side effects. However, excessive use or long use sometimes has side effects. My head hurts, I can't sleep, and my heart hurts. Therefore, the amount of writing should be well determined.

Ginseng has been used for the treatment of various diseases as his pharmacological action is revealed.

First of all, ginseng is also used as gukdo medicine. A large amount of 12 to 35% of ginseng is poured into the water and eated at once, or 2 to 4 ml of ginseng injection (1 ml contains 0.57 g of ginseng) is injected into muscle or vein. In particular, if you mix ginseng and rich well can be used as a first aid to collapse.

Ginseng is also used for cardiovascular diseases. When ginseng is used for dysfunction of the cardiac blood system, heart sound is cleared, heart contraction rhythm is restored to normal and hypotension is eliminated. Hypertension, cardiac nutrition disorders, heart pain, cirrhosis, and angina also have certain therapeutic effects. Ginseng does not affect normal blood pressure, but it increases blood pressure in small amounts and lowers blood pressure in large amounts.

Ginseng is used to treat diseases of the stomach and liver. If you use chronic gastritis with little gastric acid, stomach pain stops and tastes better. However, there is data that gastric juice secretion and gastric juice acidity has no obvious effect and data that gastric juice acidity increases. Using ginseng in acute infectious hepatitis can prevent some of the transition to chronic.

Ginseng improves the general condition of diabetics. If you use ginseng in mild diabetics, your urine sugar will decrease after two weeks and your blood sugar will drop to 40-50mg%. In people with moderate diabetes, blood sugar levels are not significantly lowered, but systemic conditions, such as thirst and symptoms, are improved.

Ginseng is also used to treat psychosis. It is effective in schizophrenia, infectious diseases and psychosis caused by addiction. But it is not effective for organic neuropathy. In addition, ginseng treats nervous breakdowns, general weakness, head pain, and decreased vision, thereby increasing weight.

Ginseng is also used to treat vulgaris. It is effective in cortical and spinal phonation and paralytic encephalopathy caused by nervous breakdown.

Ginseng also brightens the eyes and is used to treat Adison disease. Ginseng stems or leaves with 20% ethanol and make 50% tincture. First, eat 60 ~ 90ml three times a day, cool it and eat 150 ~ 300ml a day. This increases blood sugar and blood pressure in two to four months, and improves cortical hormones.

In addition, the ginseng tree (ground elm) is about 1m high and is a leafing bush. Root stock extends to the side and stem is straight and thorny. The leaves are round and shallowly divided into 5-6 branches. In June-July, small, full-colored flowers gather like umbrellas. Fruits ripen round and yellow red in August-September.

In the northern and central seas, 500 ~ 2,000m deep, deep mountain trees grow in rich soil.

Roots and rhizomes-Casseroles in autumn, washed in water and dried in the sun.

Ingredients include saponins, flavonoids and essential oils on stems, leaflets and roots. Essential oils are about 0.5% in leaves, 1% in stems and 1.8-2.4% in roots.

The stem has 2% tannins, and the roots have oil, gum and horses.

Other data suggest that the stem contains 5.5% of the essential oil, 2.7-5.1% essential oil, 6.9% of the glycosides, 0.2% of coumarin, and 11% of the resin.

In the root essential oil, sesquiterpene, echinophanaxene (C ₁₅ H ₂₄ ), sesquiterpene alcohol, echinopanerac (C ₁₅ H ₂₆ O), and sesquiterpene ketone Oflophanone were separated. It has a characteristic smell.

Function and action of alcohol extract of the root (root stem) shell has an excitatory effect on the central nervous system and antagonistic action on the median. In addition, ginseng stimulation, such as ginseng and reducing blood sugar (a component released in the water) and rats are prone to prolonged time.

Glycosides and essential oils from the roots have excitement effects on the central nervous system. Therefore, the pharmacological action component of ground root is considered to be a comprehensive composition. Root bark extract lowers blood pressure in small amounts and raises in large amounts. And exciting breathing. Glycosides lower blood pressure, stimulate the respiratory tract, and increase heart contraction. However, it does not have a marked effect on the contraction rate of the heart. There is also a pronounced pee in large quantities. Essential oils, like other essential oils, stimulate the epithelium of the kidneys to increase the amount of urine.

When the body is weakened by application, nervous breakdown, schizophrenia, mental and physical fatigue, hypogonadism, diabetes is used. Diabetes has a good therapeutic effect when used with insulin.

In folklore, stems and leaves are used as fever lowering, coughing and inflammatory drugs. Also, the plaster made from the extract of the root bark is a pain medicinal herb, which is used for decaying wounds, mowing, and rheumatism.

Ground Dull Tincture is made from 70% alcohol. General weakness, nervous breakdown, hypotension, schizophrenia, mental and physical fatigue 30-40 drops at a time before eating three times a day.

Summarizing the components, functions, and actions of the herbal medicines described above, the large yellow spots treat diseases of the kidneys and bladder, and the components contain steroid sapogenin sapogenin, which is used as a hormonal synthetic raw material. Phosphorus is contained in mornicit and loganan, and cornin contains 13% of saponin, and its functions and functions are effective for nervous breakdown, diabetes, chronic kidney disease, cystitis, and atherosclerosis. There is a glycoside, loganine and flavonoids, which have important physiological and pharmacological effects.

Gojiberry has the function of lowering blood pressure and blood sugar. Betaine, which is a component of choline metabolites, is a lipid-friendly substance, and betaine hydrochloride is a methyl-based supply to choline metabolism. Has the ability to inhibit and is available to diabetes. In addition, saponins have saponins and flavonoids in the outpost, and various free sapongenins in the embryo, such as diosgenin, glucose, grazilin, and trillin, and these saponins change the dispersibility of plasma cholesterol by acting on plasma lipoprotein. By doing so, it has a function of preventing cholesterine from depositing on the bloodline wall. Therefore, fan-masponin has a great effect on the treatment of atherosclerosis. And it works to expand the peripheral cortex and harden the heart contraction. Diosgenin, a contained ingredient, is used as a steroid hormone synthesis material.

In addition, Ogapi tree is known to restore mental and physical fatigue in the treatment of motion, improve blood pressure, improve liver function, lower anti-diabetic effect, lower cholesterol, and antioxidant effect. Ginseng tree has excitement effect on the central nervous system and Gonadotropin and blood sugar reducing action, the glycosides extracted from the roots and essential oils have excitement effects on the central nervous system, nervous breakdown, schizophrenia, mental and physical fatigue, hypogonadism, diabetes is supposed to be effective.

As described above, most of the plant medicines constituting the above-described medicinal tablet composition improve or improve the function of hypertension, diabetes, urinary tract diseases, neurological diseases, etc., which are factors that lower sexual function. The function and action of the cornus tree, which has a regular effect, the ogapi tree, which is effective in reducing sexual function, the cedar and ginseng having the function and function of gangjeong, and the large yellow and wolfberry tree, which are used as a hormonal compound, Fantoma, which has the function of expanding and hardening heart contraction, promotes the secretion of gonadotropin and stimulates blood donation by the complex action such as blood vessel expansion, endocrine excitability and gonadotropin and function. It is thought to have the function and action of tablets.

In order to determine the effect of the medicinal tablets prepared with the above herbal composition, herbal preparations were prepared in the same manner as in Example (1), and the rabbits were ingested to investigate the experimental results.

20 kg of large yellow urine selected by washing with water, 20 kg of cornus oil, 18 kg of worms, 12 kg of goji yam, 10 kg of fantail, 10 kg of ginseng, 6 kg of ogapi, 4 kg of shredded oak, 100 kg of whole herbal medicines were immersed in 350 kg of water and left to stand for 20 hours. Charged in a high-pressure part maintained at 1100 Torr of 1.5m ³ and increased for 70 minutes, cooled to room temperature, opened the high-pressure part, centrifuged and filtered, the filtrate was left still, and the filtrate was allowed to stand, and the supernatant was obtained. Concentrated and concentrated under reduced pressure to 15wt% of the supernatant weight by lyophilizing the frozen platelet, which was quenched in a state where it was spray-dispersed to a thickness of 3mm on the plate, and then lyophilized to obtain a platelet on the sponge. The crude tablet powder was dried.

Clover dry powder 50kg rabbit foods, 50kg dry rice powder 50kg, dry powder 30kg, soybean leaf dry powder 20kg, 30kg of rice bran added to the feed (A) by adding 18kg of the jeongjeongje prepared in Example (1) Added feed (B) was prepared.

Three rabbits A1, A2, A3, A4, A5 and A5, B3, B2, B3, B4, B5 in male A, 3 and 3 and a half years old. B5 was fed for three months the feed supplement (B). Separately, 10 female rabbits (C1 ~ C10) in estrous periods grown for 1 year were prepared.

Female rabbits (C1 to C10) were put into breeding barrels of male rabbits (A1 to A5) and (B1 to B5) one by one, and observed for 2 days, and the number of matings was measured to obtain the results as shown in Tables (1) and (2).

Number of rabbit copulations in group A fed mixed feed (A). Japanese group A is divided A1 A2 A3 A4 A5 One One One 0 One One 2 0 One 0 One 0 system One 2 0 2 One

Number of rabbit copulations in group B fed with fertilizer feed (B). Group B is divided into B1 B2 B3 B4 B5 One 3 2 One 3 4 2 2 One 2 One One system 5 3 3 4 5

Observing Tables (1) and (2) above, group A rabbits fed the mixed feed (A) had a total number of copulations of 6 times for 2 days, and the total number of group B rabbits fed the feed (B) with the addition of the tablets The number of copulations was 20, and the number of copulations in group B was much higher than that of group A rabbits.

In addition, after two days elapsed mating due to the rebellion of female rabbits.

On the contrary, the mixed feed (A) was fed to the rabbits B1 to B5 of the group B, and the feed supplement (B) was fed to the rabbits A1 to A5 of the group A to breed for 3 months. Put into the breeding barrels of group A and B and observed for 2 days to measure the number of mating to obtain the same results as Table (3) and Table (4).

Number of rabbit copulations in group B fed with mixed feed (A). Group B is divided into B1 B2 B3 B4 B5 One 2 One 0 2 2 2 2 One One One One system 4 2 One 3 3

Number of rabbit copulations in group A fed with fertilizer feed (B). Japanese group A is divided A1 A2 A3 A4 A5 One 2 2 2 3 2 2 One 2 One 2 2 system 3 4 3 5 4

In Table (3), the group B did not eat the fertilizer feed (B) for 13 months with 13 times of rabbit mating. Ingestion of fermented dietary supplement (B) for 3 months, 13 times the number of mating three months ago when the mixed feed (A) showed that the number of mating was significantly better than 6 times.

In addition, when comparing the condition of group A rabbits in table (1) and group B rabbits in table (2), the rabbits in group A have a lot of time to lie down and the rabbits in group B have a lot of time to stand and act. Could.

In addition, Examples (5) to (7) will be given to determine the effect of the tablets extracted with an aqueous alcohol solution.

20 kg of large yellow urine selected by washing with water, 20 kg of cornus oil, 18 kg of tofu, 12 kg of wolfberry, 10 kg of fantail, 10 kg of ginseng, 10 kg of cucumber, 6 kg of ginseng and 4 kg of shredded whole vegetable herbal medicines immersed in 300 kg of 15wt% alcohol solution After standing still, it was charged to a high-pressure part maintained at 1100 Torr and increased for 80 minutes. After cooling to room temperature, the high-pressure part was opened, centrifugation of the liquid solution, the filtrate was left still, the supernatant was obtained, and the temperature was maintained at 50 ° C under reduced pressure. After condensation under reduced pressure, the concentrated solution concentrated to 12wt% with respect to the total weight of the supernatant was lyophilized and lyophilized the frozen platelet, which was quenched in a state of uniform distribution at a thickness of 3mm on the plate, to obtain a corpus cavernosum, and then pulverized. The crude powder dried to% was obtained.

18 kg of fertilizer was added to the mixed feed (D) which mixed rabbit's favorite clover dry powder 50kg, fingerlings 50kg, bitter dry powder 30kg, cabbage leaf dry powder 20kg, and rice bran 30kg. .

E1, E2, E3, E4, E5, male E group 3 ~ 3 and a half years old, F1, F2, F3, F4, F5 10 rabbits E1 ~ E5 fed mixed feed (D) and F group F1 to F5 were fed with fermented feed (D ') and bred for 3 months. Separately, 10 female rabbits (G1 ~ G5) in estrous periods grown for 1 year were prepared.

Female rabbits (G1 to G10) were put into breeding barrels of male rabbits (E1 to E5) and (F1 to F5) one by one, and the number of matings was measured for 2 days to obtain the results as shown in Tables (5) and (6).

Number of copulations of group E rabbits fed a mixed feed (D). Day ＼ classification E1 E2 E3 E4 E5 One One One 0 One One 2 0 One One One 0 system One 2 2 2 One

The number of copulations of group F rabbits fed D 'fertilizer. Day ＼ classification F1 F2 F3 F4 F5 One 2 3 2 2 2 2 3 One 2 One 4 system 5 4 4 3 6

Observing Tables (5) and (6) above, E group rabbits fed mixed feed (D) had 8 times of mating for 2 days, and the total number of fertilizations of group F fed rabbit fertilizer (D ') At 22 times, the number of matings in group F was much higher than that of group D.

The measurement method was equipped with a sound recorder in each breeding room was measured by the sound of copulation.

Claims (2)

After removing the foreign matter and washing with water, dried 20 large parts of large yellow spot, 20 parts by weight of cornus oil, 18 parts by weight of worms, 12 parts by weight of goji berry, 10 parts by weight of fantail, 10 parts by weight of ginseng, 6 parts by weight of Ogapi, ginseng (Ginseng tree) ) Add 3 ~ 4 times of water to the total weight of the herbal medicine consisting of 4 parts by weight, extract it for 12 ~ 24 hours at room temperature, boil it for 60 ~ 80 minutes in the high pressure part maintained at 1100 Torr, and then cool it to room temperature to open the high pressure part. Centrifuged to obtain the extract of the herbal composition, and the filtered filtrate was left to stand, and the supernatant was separated. The supernatant was maintained at a temperature of 40 to 50 ° C. and concentrated under reduced pressure to obtain a concentrated extract which was concentrated to 10-15 wt%. The concentrated solution was sprayed and dispersed on a plate plate to form a thickness of 2 to 3 mm, and then quenched and dried in a freeze drying room to obtain a dry matter on a spongy body. Method for producing a tablet (A) characterized in that the vacuum packing the sterilized powder with drying and sterilization in a far-infrared radiation chamber to be maintained in 2wt% moisture.
The method of claim 1, wherein the extract is 10-15 wt% alcohol aqueous solution instead of water.